Ribonucleic Acid News, Research  Ribonucleic Acid News, Research
NIH scientists zero in on genes associated with AMD National Eye Institute scientists led a collaborative study and zeroed in ... A protein with a role in sensing cell damage and viral infections is a new target for the treatment of pulmonary hypertension, ... Study offers new insight on mechanism underlying control of gene expression Researchers have provided new insight on the ... New analytic method can precisely detect viral infections using immune responses Cytomegalovirus is widespread and remains in ...
https://www.news-medical.net/?tag=/Ribonucleic+Acid
Pagets Disease News, Research  Paget's Disease News, Research
New study reveals measles viral gene plays key role in development of PD A gene from the measles virus plays a key role in the ... VCP gene mutations cause neurological conditions including IBMPFD and ALS New research, published in Neuron, gives insight into ... Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone Researchers supported by The ALS ... Connection to HIV treatment services helps gay, bisexual population to achieve viral suppression ...
https://www.news-medical.net/?tag=/Pagets-Disease
Lentivirus Applications  Lentivirus Applications
The most important application of lentiviral vectors is gene therapy which includes the transfer of therapeutic genes into the ... Lentivirus is a genus in the family of Retroviridae that is very suitable for remodeling into gene transfer vectors due to its ... Designing Lentiviral Gene Vectors. In: Xu K (Ed). Viral Gene Therapy. InTech, 2011; pp. 263-284. ... The most important application of lentiviral vectors is gene therapy which includes the transfer of therapeutic genes into the ...
https://www.news-medical.net/life-sciences/Lentivirus-Applications.aspx
Passive Smoking News, Research  Passive Smoking News, Research
Study identifies genetic factors linked to severity of acute viral bronchiolitis A scientific study conducted at the State ... has identified genetic factors associated with the severity of acute viral bronchiolitis. The study was supported by the Sao ... Researchers discover new genes involved in Alzheimer's Disease. Exosomes: Are They All Alike and Why Does it Matter?. Haiying ...
https://www.news-medical.net/?tag=/Passive+Smoking
What Causes Cancer?  What Causes Cancer?
Viral and bacterial infections. Some cancers can be caused by infections with pathogens. Notable among these include liver ... Common examples are inherited breast cancer and ovarian cancer genes including BRCA1 and 2. Li-Fraumeni syndrome includes ... what seems to happen is that certain vital genes which control how cells divide and multiply are damaged or altered; many ... defects in the p53 gene that leads to bone cancers, breast cancers, soft tissue sarcomas, brain cancers etc. Those with Down's ...
https://www.news-medical.net/health/What-Causes-Cancer.aspx
Analytical and Preparative Chromatography  Analytical and Preparative Chromatography
toxicology, biology, medicine (purification of monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for gene ...
https://www.news-medical.net/life-sciences/Analytical-and-Preparative-Chromatography.aspx
Affibody Molecule Discovery and Uses  Affibody Molecule Discovery and Uses
Viral particles. Viruses, such as human adenoviruses have been used as vector for gene therapy in cancer. To improve their ... Association found between gene variant and lung disease in the form of systemic vasculitis ... These particles consist of polymers, vesicular components, or viral particles. Due to the properties of affibodies, they can ...
https://www.news-medical.net/life-sciences/Affibody-Molecule-Discovery-and-Uses.aspx
CRISPR Interference (CRISPRi) for Gene Suppression  CRISPR Interference (CRISPRi) for Gene Suppression
... providing adaptive immunity against viral infection. Using these sequences, scientists have recently developed a new genetic ... To allow specific genes to be targeted, synthesis single guide RNAs (sgRNA) can be manufactured, composed of chimeric noncoding ... It can affect the nearby genes, sometimes leading to unexpected adverse effects. Additionally, it relies on the use of PAM and ... In conclusion, the use of CRISPRi technique would greatly help in the field of germline gene therapy and in developing sequence ...
https://www.news-medical.net/life-sciences/CRISPR-Interference-
Liver Cancer News, Research  Liver Cancer News, Research
Breast cancer gene could be key to developing targeted therapy for hepatoblastoma Hepatoblastoma is a rare form of liver cancer ... Hepatitis C is a viral infection that affects the liver and is usually acquired from infected blood. Formerly called non-A, non ... Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis ...
https://www.news-medical.net/?tag=/Liver+Cancer
RNA Interference (RNAi) in Biotechnology  RNA Interference (RNAi) in Biotechnology
RNA interference is a rapidly developing method of gene silencing. It is used to genetically engineer plants against stress, ... Later, the vsiRNAs target and conceal gene expression and protein translation of the viral and target genes. ... RNA interference utilizes a virus-induced gene silencing (VIGS) system to improve resistance to viral diseases in plants. This ... Host gene silencing-hair pin RNAi (HGS-hpRNAi) is considered to be a more stable method of gene silencing in plants. The ...
https://www.news-medical.net/life-sciences/RNA-interference-in-biotechnology.aspx
UCLA research could lead to simple saliva test for early diagnosis of deadly diseases  UCLA research could lead to simple saliva test for early diagnosis of deadly diseases
Tags: Bioinformatics, Blood, Body Fluids, Cancer, Cell, Dentistry, Diabetes, Diagnostics, DNA, Enzyme, Gastric Cancer, Genes, ... Although their function is not yet known, Xiao said they may protect the body from viral infection. ... One microRNA can regulate hundreds of genes, she said.. The scientists compared microRNA levels in saliva to those in the blood ...
https://www.news-medical.net/news/20141030/UCLA-research-could-lead-to-simple-saliva-test-for-early-diagnosis-of-deadly-diseases.aspx
DNA and Technology  DNA and Technology
Usually viral DNA is used as the vehicle that goes and gets introduced into a foreign gene. This is called transfection. ... Gene therapy involves using tiny molecules that carry the corrective enzyme or medication to the exact defective gene and ... The expression of these genes, i.e., the amount of protein products to be made in a cell, is tightly regulated so as to meet ... It is estimated that the human genome has about 30,000 genes, which, surprisingly, only account for ~3% of the genome. ...
https://www.news-medical.net/life-sciences/DNA-and-Technology.aspx
Northern Blot / RNA Blot  Northern Blot / RNA Blot
Gene expression studies - to observe overexpression of cancer-causing genes and gene expression in case of transplant rejection ... For detection of viral microRNAs that play key roles in viral infection ... Study identifies more than 6,000 antibiotic resistance genes found in gut bacteria ...
https://www.news-medical.net/life-sciences/Northern-Blot-RNA-Blot.aspx
RNA Types  RNA Types
On the other hand small interfering RNAs (siRNA; 20-25 nt) are often produced by breakdown of viral RNA, there are also ... These RNAs serve to regulate the process of gene expression. MicroRNAs (miRNA; 21-22 nt) for example are found in eukaryotes ... Study points at lysosomal storage disorder genes as potential key contributors to Parkinson's ... These are encoded by RNA genes and also derived from mRNA introns. ...
https://www.news-medical.net/life-sciences/RNA-Types.aspx
Seqüências de manipulação do RNA usando CRISPR-Cas13  Seqüências de manipulação do RNA usando CRISPR-Cas13
Desde que as mudanças aos níveis do gene são somente transientes, esta permite que os cientistas investiguem o gene possível ... Com o sistema de CRISPR-CAS, o ADN viral é cortado nos fragmentos que são armazenados em um locus de CRISPR. Estes locus podem ... Spatial Gene Expression Profiling of Neurological Disorders. Cedric Uytingco, PhD. In this interview, Cedric Uytingco discusses ... Os genes associados CRISPR (Cas) do sistema são encontrados igualmente próximo, codificando para endonucleases e helicases. ...
https://www.news-medical.net/life-sciences/Manipulating-RNA-sequences-using-CRISPR-Cas13-
Lentivirus Genome  Lentivirus Genome
Gene vectors are also used extensively in basic biomedical research. ... Vectors derived from lentiviruses can be used for treatment strategies dependent on both transgene expression and gene ... The complex lentiviruses contain other accessory genes as well, responsible for precise orchestration of viral replication, ... It contains the elements required for vector packaging such as structural proteins, HIV genes (except the gene env because its ...
https://www.news-medical.net/life-sciences/Lentivirus-Genome.aspx
Scientists identify novel way to target lung cancer through KRAS gene  Scientists identify novel way to target lung cancer through KRAS gene
... one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully. ... UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, ... The KRAS gene (Kirsten rat sarcoma viral oncogene homolog), produces proteins called K-Ras that influence when cells divide. ... Tags: Cancer, Cancer Prevention, Cell, Children, Education, Enzyme, Fatty Acids, Gene, Genes, Genetic, Genetics, Geriatrics, ...
https://www.news-medical.net/news/20160729/Scientists-identify-novel-way-to-target-lung-cancer-through-KRASc2a0gene.aspx
What is MicroRNA?  What is MicroRNA?
... contain different gene expression profiles, thus proper understanding of regulatory mechanisms involved in such expression ... Gene expression in cells and tissues of every complex organism is precisely controlled and largely dependent on different ... Almost all siRNAs (regardless of their viral or other origin) silence the same locus from which they were derived. On the other ... laboratory in 1993 while studying the gene lin-14. At the same time, Gary Ravkun identified the first miRNA target gene. Those ...
https://www.news-medical.net/life-sciences/What-is-MicroRNA.aspx
Herpes Simplex Virus 2 News, Research - Page 14  Herpes Simplex Virus 2 News, Research - Page 14
Experts on the Gene Therapy Advisory Committee have given the go ahead for a large clinical trial of a new treatment for ... Promising lead in developing anti-viral drugs with the potential to fight HIV and HSV Dr Norelle Daly, from UQ's Institute for ... New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients ... Herpes Simplex Virus-2 is a sexually transmitted viral infection, which often produces painful sores, usually in the genital ...
https://www.news-medical.net/?tag=/Herpes-Simplex-Virus-2&page=14
The Baculovirus Expression Vector System (BEVS)  The Baculovirus Expression Vector System (BEVS)
The baculovirus polyhedrin or p10 can be replaced with a gene of interest, which allows for the promoters to expresses the gene ... This is due to the structural changes within a host following a viral infection (referred to as the cytopathogenic effect). ... Vectors for gene delivery. AcMNPV is a virus that can only infect insects. Past studies discovered that mammalian cells were ... Baculovirus can mediate gene expression in the immortal HeLa cell line or the fibroblast-like COS-7 cells, by using chimeric ...
https://www.news-medical.net/life-sciences/The-Baculovirus-Expression-Vector-System-
Cas9 News, Research  Cas9 News, Research
New gene-editing study finds protective genes against Zika virus Tel Aviv scientists have discovered certain genes that protect ... New tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral ... SATI gene editing could replace CRISPR Scientists have developed a new gene editing tool called SATI that is safer than CRISPR. ... Salk researchers develop new gene-editing tool to target broad range of mutations, cell types The ability to edit genes in ...
https://www.news-medical.net/?tag=/Cas9
Researchers unravel how Zika virus manipulates the human immune system  Researchers unravel how Zika virus manipulates the human immune system
Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that ... these approaches allow Zika virus to stop macrophages from making many genes involved in immune cell recruitment and anti-viral ... Tags: Allergy, Bacteria, Brain, Cell, Gene, Genes, Immunology, Laboratory, Macrophage, Macrophages, microcephaly, Molecule, ... a crucial part of the cell's gene transcription machinery. The loss of RNA Pol II is especially notable at genes responsible ...
https://www.news-medical.net/news/20180911/Researchers-unravel-how-Zika-virus-manipulates-the-human-immune-system.aspx
Herpes Simplex Virus 2 News, Research - Page 5  Herpes Simplex Virus 2 News, Research - Page 5
Novel viral therapy to treat specific types of cancer in children Parents do everything they can to protect their children ... Researchers find that people affected by cold sores have mutation in gene Why some people are troubled by cold sores while ... Spatial Gene Expression Profiling of Neurological Disorders. Cedric Uytingco, PhD. In this interview, Cedric Uytingco discusses ... Discovery of pressure-driven infection mechanism opens door to new treatments for viral infections The virus that causes those ...
https://www.news-medical.net/?tag=/Herpes-Simplex-Virus-2&page=5
Innovative handheld genetic sequencing device helps scientists track evolution of Zika virus  Innovative handheld genetic sequencing device helps scientists track evolution of Zika virus
... with the genes comparable to clocks in that their mutations indicate when different viral isolates diverged. ... Tags: Blood, Chikungunya, Evolution, Fever, Gene, Genes, Genetic, Genome, Genomic, Laboratory, Light, Pathogen, Public Health, ... At the time, we had sequenced seven viral isolates. The number of samples was insufficient to give us a broad notion of Zika's ... According to the scientists, their aim is to monitor the viral genome's evolution and to understand what has happened, so as to ...
https://www.news-medical.net/news/20170810/Innovative-handheld-genetic-sequencing-device-helps-scientists-track-evolution-of-Zika-virus.aspx
A tecnologia da descoberta oferece a esperança nova aos povos com glaucoma, retinite e degeneração macular  A tecnologia da descoberta oferece a esperança nova aos povos com glaucoma, retinite e degeneração macular
... www.polymtl.ca/salle-de-presse/en/newsreleases/major-step-toward-non-viral-ocular-gene-therapy-using-laser-and-nanotechnology ... www.polymtl.ca/salle-de-presse/en/newsreleases/major-step-toward-non-viral-ocular-gene-therapy-using-laser-and-nanotechnology ... tornando o possível injectar eficazmente drogas ou genes em áreas específicas do olho. Era uma outra vitória para o Meunier de ...
https://www.news-medical.net/news/20181120/17452/Portuguese.aspx