... which target c-MYC, and also due to miR-302b-dependent c-MYC induction. c-Myc transactivates SOX2, providing yet another feed- ... MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity. Cell Stem Cell 2010;7:31-5. ... Cytokine exposures increased c-MYC, SOX2, and NANOG expression in both ER− and ER+ breast cancer lines (Fig. 5A). Because Src ... Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008;134:521-33. ...