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*  Home | G3: Genes | Genomes | Genetics
Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System Yuanyuan Xu, Yong Wang, Yuning Song ... The Effect of Balancing Selection on Population Differentiation: A Study with HLA Genes Débora Y. C. Brandt, Jônatas César, ... A Missense Mutation in the Vacuolar Protein Sorting 11 (VPS11) Gene Is Associated with Neuroaxonal Dystrophy in Rottweiler Dogs ... Cotton Late Embryogenesis Abundant (LEA2) Genes Promote Root Growth and Confer Drought Stress Tolerance in Transgenic ...
http://www.g3journal.org
*  Gene regulatory networks | PNAS
Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression ... The Special Feature on gene regulatory networks in this issue of PNAS highlights an emerging field in the biosciences: gene ... Environmental factors, not genes constitute most disease risk. Myriad approaches are attempting to use the latest science and ... Causality in the regulatory genome: The reasons why genes are expressed when and where they are in the spatial domains of the ...
http://www.pnas.org/content/102/14/4935.full
*  Identification of a new hearing impairment gene implicates the involvement of the S1PR gene family in human disease | Baylor...
An international group of researchers led by those at Baylor College of Medicine find gene mutation associated with hearing ... Regie Lyn P. Santos-Cortez said that the foot abnormality is most likely caused by a gene near S1PR2 and not the gene itself. ... Identification of a new hearing impairment gene implicates the involvement of the S1PR gene family in human disease. ... Identification of a new hearing impairment gene implicates the involvement of the S1PR gene family in human disease ...
https://www.bcm.edu/news/molecular-and-human-genetics/hearing-impairment-gene-implicates-s1pr-gene
*  Histones Gene Family | HUGO Gene Nomenclature Committee
Genes contained within the family: 116 Approved Symbol. Approved Name. Previous Symbols. Synonyms. Chromosome. ... They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation ...
https://www.genenames.org/cgi-bin/genefamilies/set/864
*  Cathepsins (CTS) Gene Family | HUGO Gene Nomenclature Committee
Genes contained within the family: 15 Approved Symbol. Approved Name. Previous Symbols. Synonyms. Chromosome. ...
https://www.genenames.org/cgi-bin/genefamilies/set/470
*  EF-hand domain containing Gene Family | HUGO Gene Nomenclature Committee
Genes contained within the family: 219 Approved Symbol. Approved Name. Previous Symbols. Synonyms. Chromosome. ...
https://www.genenames.org/cgi-bin/genefamilies/set/863
*  Protein phosphatase 1 regulatory subunits (PPP1R) Gene Family | HUGO Gene Nomenclature Committee
Please see our Protein phosphatases, catalytic subunits page to view the PPP1C genes, along with all other PPP genes. ... Genes contained within the family: 181 Approved Symbol. Approved Name. Previous Symbols. Synonyms. Chromosome. ...
https://www.genenames.org/cgi-bin/genefamilies/set/694
*  RAS type GTPase family (RAS) Gene Family | HUGO Gene Nomenclature Committee
Genes contained within the family: 31 Approved Symbol. Approved Name. Previous Symbols. Synonyms. Chromosome. ...
https://www.genenames.org/cgi-bin/genefamilies/set/389
*  BRCA2 gene - Genetics Home Reference - NIH
BRCA2 gene. BRCA2, DNA repair associated. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All Close ... Most BRCA2 gene mutations lead to the production of an abnormally small, nonfunctional version of the BRCA2 protein from one ... The BRCA2 gene provides instructions for making a protein that acts as a tumor suppressor. Tumor suppressor proteins help ... As a result, less of this protein is available to help repair damaged DNA or fix mutations that occur in other genes. As these ...
https://ghr.nlm.nih.gov/gene/BRCA2
*  NCI Researchers Discover Genes That Are Turned On at High Levels in Tumor-Associated Blood Vessels of Mice and Humans |...
These genes, and the proteins they encode, are important new potential targets for novel drugs that could selectively cut off a ... has uncovered a set of genes that are turned on, or expressed, at high levels only in the blood vessels that feed tumors in ... Among the genes identified was CD276, a gene that encodes a protein located on the cell surface, as well as other known and ... NCI Researchers Discover Genes That Are Turned On at High Levels in Tumor-Associated Blood Vessels of Mice and Humans. ...
https://www.nih.gov/news-events/news-releases/nci-researchers-discover-genes-are-turned-high-levels-tumor-associated-blood-vessels-mice-humans
*  London Regional Transgenic and Gene Targeting Facility - Western University
Gene Targeting Facility (LRTGT) was established in 2003 as a collaborative endeavor between Western University, Lawson Health ... The Transgenic and Gene Targeting Facility in London has generated four targeted gene replacements and more than a dozen ... London Regional Transgenic and Gene Targeting Facility. Victoria Research Laboratories, A5-134. London, Ontario, Canada, Tel: ... London Regional Transgenic and Gene Targeting Facility. Schulich Medicine & Dentistry,. Western University. London, Ontario. ...
http://www.schulich.uwo.ca/lrtgt/
*  PSEN1 gene - Genetics Home Reference
Almost all PSEN1 gene mutations change single building blocks of DNA (nucleotides) in a particular segment of the PSEN1 gene. ... Wang B, Yang W, Wen W, Sun J, Su B, Liu B, Ma D, Lv D, Wen Y, Qu T, Chen M, Sun M, Shen Y, Zhang X. Gamma-secretase gene ... PSEN1 gene. presenilin 1. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All Close All ... The PSEN1 gene provides instructions for making a protein called presenilin 1. This protein is one part (subunit) of a complex ...
https://ghr.nlm.nih.gov/gene/PSEN1
*  qPCR INFO PORTAL - the reference in real-time PCR
Gene-Quantification.com Gene-Quantification.info - The reference in qPCR - Academic & Industrial Information Platform ... Gene-Quantification.com Gene-Quantification.info - The reference in qPCR - Academic & Industrial Information Platform - ...
http://infoportal.gene-quantification.info
*  Nature
Gene editing reveals the effect of thousands of variants in a key cancer gene Gene editing has now been used to introduce every ... possible single-nucleotide mutation into key protein-coding regions in the cancer-predisposition gene BRCA1, to identify the ...
http://www.nature.com
*  APC gene - Genetics Home Reference - NIH
Senda T, Shimomura A, Iizuka-Kogo A. Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene. Anat Sci ... APC gene mutations can cause tumors in individuals without this inherited disease. APC gene mutations are found in about 10 to ... APC gene. APC, WNT signaling pathway regulator. Enable Javascript to view the expand/collapse boxes.. Printable PDF Open All ... APC gene mutations typically cause formation of desmoid tumors in the abdomen, but these tumors can also occur in other parts ...
https://ghr.nlm.nih.gov/gene/APC
*  ATP1A2 gene - Genetics Home Reference - NIH
The ATP1A2 gene provides instructions for making one part (the alpha-2 subunit) of a protein known as a Na+/K+ ATPase. This ... ATP1A2 gene. ATPase Na+/K+ transporting subunit alpha 2. Enable Javascript to view the expand/collapse boxes.. Printable PDF ... ATP1A2 gene mutations can also cause sporadic hemiplegic migraine. The signs and symptoms of this condition are identical to ... Others prevent the production of any protein from one copy of the ATP1A2 gene in each cell. As a result, less potassium is ...
https://ghr.nlm.nih.gov/gene/ATP1A2
*  HLA-DPB1 gene - Genetics Home Reference - NIH
The HLA-DPB1 gene belongs to a group of MHC genes called MHC class II. MHC class II genes provide instructions for making ... The HLA-DPB1 gene provides instructions for making a protein that plays a critical role in the immune system. The HLA-DPB1 gene ... The protein produced from the HLA-DPB1 gene attaches (binds) to the protein produced from another MHC class II gene, HLA-DPA1. ... HLA-DPB1 gene. major histocompatibility complex, class II, DP beta 1. Enable Javascript to view the expand/collapse boxes.. ...
https://ghr.nlm.nih.gov/gene/HLA-DPB1
*  Induction of Immunity to Prostate Cancer Antigens: Results of a Clinical Trial of Vaccination with Irradiated Autologous...
... and ex vivo gene transfer. This was the first NIH Office of Recombinant DNA Activities-approved trial of human gene therapy for ... Carducci M. A., Ayyagari S. R., Sanda M. G., Simons J. W. Gene therapy for human prostate cancer. Cancer (Phila.), 75: 2013- ... GM-CSF gene-transduced PCA vaccines represent only one of several new approaches to active specific immunotherapy of PCA, which ... GM-CSF gene-transduced PCA vaccines increased antibody titers against prostate tumor cell line-associated antigens. This ...
http://cancerres.aacrjournals.org/content/59/20/5160
*  Preclinical and clinical advances in transposon-based gene therapy | Bioscience Reports
... gene addition') or correcting non-functional mutated genes in the target genome (referred to as 'gene correction'). Gene ... in RefSeq genes) compared with SB (~25-45% in RefSeq genes) and Tol2 (~40% in RefSeq genes). In addition, PB and Tol2 ... 2017) Gene therapy for ADA-SCID, the first marketing approval of an ex vivo gene therapy in Europe: paving the road for the ... Transposon-based gene therapy in clinical trials. The clinical use of transposon systems for gene transfer was pioneered by Dr ...
http://www.bioscirep.org/content/37/6/BSR20160614
*  Restless Genes
The classic culture-gene example is the rapid rise of a gene for digesting lactose. If you lack this gene, you'll have trouble ... Culture and genes started selecting for each other: A new culture made a gene more valuable, and as the gene spread through the ... no one gene or set of genes can hardwire us for exploration. More likely, different groups of genes contribute to multiple ... Sometimes a gene rides such a wave passively, more or less by accident-the gene just happens to be common in the leading ...
https://www.nationalgeographic.com/magazine/2013/01/restless-genes/
*  Understanding Plant Genes
Mendelian Genes Define the Commitment to Flowering- Understanding Plant Genes-The Cauliflower Gene-The "fruit-full" gene. A ... Understanding Plant Genes. Photos: (1) phenotype of the APETALA1 CAULIFLOWER double mutant. (A) phenotype of the APETALA1 ... Caption: Genes control Flowering Development in Plants: ...
https://www.nsf.gov/news/speeches/colwell/rc03_marymount/tsld014.htm
*  Proneural genes - Wikipedia
Once Notch is activated, the activity of proneural genes decreases in these cells, probably due to the activation of genes in ... On the other hand, proneural genes mutants fail to develop neural precursor cells. The proneural genes are expressed in groups ... Skeath, J. B.; Panganiban, G. F.; Carroll, S. B. (1994). "The ventral nervous system defective gene controls proneural gene ... Co-expression of proneural genes in brain neuroblasts is transient and varies with the developmental stage. Proneural gene ...
https://en.wikipedia.org/wiki/Proneural_genes
*  Stolen Genes
... Award-Winning Author Speaks About Her Bestselling Book The Immortal Life of Henrietta Lacks ... What would you do if you discovered that one of your family members' genes had been harvested for medical testing without her ... HeLa cells helped develop the polio vaccine and aided in the success of in vitro fertilization, cloning, and gene mapping. And ...
http://www.independent.com/news/2011/apr/05/stolen-genes/
*  Jewish Genes
main questions was:community of J.genes,links to neighbours of diaspora and Middle East genes.As allways these links must be ... If your gene pool and your history say you are then you are, no one should ever have that right and their history taken away ... For one, genes of course do not make a cultural identity or religoius identity. They can however show a link to a particular ... I would say you have more Jewish genes then I do, frankly I would consider you as a Jew. It makes me angry that we don't accept ...
http://www.aish.com/ci/sam/48937817.html
*  Guardian genes | New Scientist
They injected trout with the genes for antibodies against viral. haemorrhagic septicaemia virus. This protected the fish from ... Conventional DNA vaccines contain genes that code for proteins resembling. those of viruses or bacteria. These proteins trigger ...
https://www.newscientist.com/article/mg16822633-300-guardian-genes/