EF1A1 and RPL7 were also listed as the best reference genes when exploring the expression levels of the six genes in various ... Real time RT-PCR has become an important tool for analyzing gene expression in fish. Although several housekeeping genes have ... Results: The expression of all six genes was relatively stable from the unfertilized egg until 12 day degrees post ... None of the six reference genes can be recommended as reference gene candidates in ConA-PMA stimulated leucocytes. However, ...

This was associated with increased total antioxidant capacity in plasma and increased liver gene expression of mitochondrial ...

Methods and Results: The study includes 11 open access gene expression data sets which collectively provide information on 2423 ... Also, the vascular invasion signature was associated with several other gene expression profiles related to vascular biology ... An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer. ... The 18-gene signature showed consistent associations with aggressive features of breast cancer, like high tumor grade, hormone ...

Gene expression is regulated through cis-regulatory elements (CREs), among which are promoters, enhancers, Polycomb/Trithorax ... Objective Properties of gene products can be described or annotated with Gene Ontology (GO) terms. But for many genes we have ... GAPGOM-an R package for gene annotation prediction using GO metrics  van Mourik, Casper; Ehsani, Rezvan; Drabløs, Finn ( ...

Furthermore, we found a positive correlation between AXL expression and autophagy-associated gene signatures in a large cohort ... AXL kinase inhibition by the small molecule inhibitor bemcentinib or siRNA mediated AXL gene silencing was reported to inhibit ... and AXL expression is associated with drug resistance and diminished long-term survival in a wide range of malignancies, ... and abrogated the transcription of autophagy-associated genes in vivo. ...

Plasma and gut samples for histology, gene expression and biochemical analyses were collected at weeks 2 and 4 during H2S ... Specifically, the high dose of 5 µg/L H2S upregulated the expression of sulfide: quinone oxidoreductase (sqor2), bclassociated ...

... we decided to analyse the mRNA expression of genes known to be involved in control of feed intake, appetite and digestion in ... Npy mRNA expression indicated a central orexigenic role. The expression profile of pyyb indicate that this hormone is involved ... We investigated the spatial (brain and gut) and temporal (10 and 20 dpff) expression profile of cholecystokinin paralogues ( ... we also analysed how their expression profile was affect by feeding. Our results suggest that cck1 is involved in the ...

Cap analysis of gene expression (CAGE) is a high-throughput method for transcriptome analysis that provides a single base-pair ...

To identify genes with differential expression in BD, we performed expression quantitative trait loci (eQTL) analysis on BD- ... using three different gene expression databases. We found 307 unique eQTL genes regulated by BD-associated variants, of which ... Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to ... we performed differential expression analysis of these genes in brain tissue samples from BD patients (n = 42) and healthy ...

The number of differentially expressed genes (DEGs) having at least 0.75 log2-fold change was elevated in high, compared to low ... the highest PFOS concentration showed almost similar transcript expression patterns compared to the highest mixture exposure ... Shortlisted DEGs that were specifically annotated to reproduction associated gene ontology (GO) terms were observed only in the ...

The FKBP5 expression and the FKBP51 protein levels in leukocytes was determined before and after intravenous infusion of 100 mg ... rs1360780 in the FKBP5 gene encoding FKBP51 and the individual glucocorticoid sensitivity in patients with Addisons disease. ... The FKBP5 expression, FKBP51 protein levels and ACTH and cortisol levels showed no genotype specific pattern in our study. ...

Fabry disease is a rare disorder caused by variations in the alpha-galactosidase gene. To a degree, Fabry disease is manageable ... Here we show how hormone therapy affects CACNA1D expression and CaV1.3 .... * Increased Plasma Levels of Triglyceride-Enriched ...

Genomic Signatures of Local Adaptation under High Gene Flow in Lumpfish-Implications for Broodstock Provenance Sourcing and ... and brain expression of selected neuropeptides and one receptor ... ... sea temperature combined with dietary methionine levels affect feed intake and appetite-related neuropeptide expression in the ...