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*  Abordagem clínico-laboratorial no diagnóstico diferencial de hipercalcemia
Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism: Effects of mutant gene dosage and phenotype. J ... A maioria dos casos são mutações inativadoras do gene do receptor sensor de cálcio. Indivíduos homozigotos para o gene ... Mutatios in the human Ca2+-sensingreceptor gene that cause familial hypocalciuric hypercalcemia. Am J Hum Genet 1995;56:1075-9 ... Hereditary hyperparathyroidism-jaw tumor syndrome: The endocrine tumor gene HRPT2 maps to chromosome 1q21-q31. Am J Hum Genet ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27301999000600014
*  ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice
Diabetic Nephropathy Induced by Increased Ace Gene Dosage Is Associated with High Renal Levels of Angiotensin (1-7) and ... ACE gene polymorphisms might also account for these discrepancies since ACE gene variance is associated with increased risk of ... or insert an extra copy of a gene adjacent to the existing gene (knock in). ... ACE gene titration in mice uncovers a new mechanism for ACE on the control of body weight. Physiol Genomics. 2005;20(2):173-82 ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100245&lng=es&nrm=iso&tlng=es
*  Clinics - vol.73
ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice. Moraes ...
http://www.scielo.br/scielo.php?script=sci_issuetoc&pid=1807-593220180001&lng=en&nrm=iso
*  DOSE NÃO USUAL DE VARFARINA PARA ALCANÇAR RNI TERAPÊUTICA EM UMA CRIANÇA DE QUATRO MESES: FATORES DE RISCO NÃO GENÉTICOS AINDA...
6. Zhang J, Tian L, Zhang Y, Shen J. The influence of VKORC1 gene polymorphism on warfarin maintenance dosage in pediatric ... 8 It is worth noting that VKORC and CYP2C9 gene polymorphism screening have been issued as an essential laboratory test before ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822017000400472&lng=pt&nrm=iso&tlng=en
*  Clinical, cytogenetic and toxicological studies in rural workers exposed to pesticides in Botucatu, São Paulo, Brazil
Toxicological dosages of copper, zinc and manganese (metals found in some pesticides), hepatic enzyme dosage (GOT, GPT, AR) and ... Pesticides can cause gene mutations and chromosomal aberrations in exposed individuals. We have investigated 24 workers exposed ... The exposed group showed significantly lower manganese dosage and acetylcholinesterase activity, and significantly higher ...
http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-311X1998000700011&lng=en&nrm=iso&tlng=en
*  Hypothyroidism in children: diagnosis and treatment
TH receptor proteins are coded by two genes: a gene, located in chromosome 17, and b gene, located in chromosome 3. The ... Currently, T4 and TSH dosages may also be carried out. TSH values are considered significant when around 20 to 25 µU/mL. Taking ... Damante G. Thyroid defects due to Pax 8 gene mutation. Eur J Endocrinol. 1998;139:563-6. [ Links ]. 13. Macchia PE, Lapi P, ... Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia. Nat Genet. 1998; ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572007000700013&lng=en&nrm=iso&tlng=en
*  The effect of eurycoma longifolia jack on spermatogenesis in estrogen-treated rats
... genes.37 Admittedly, the present study did not look into P450 aromatase enzyme levels, signaling pathways or the estrogen gene ... the dosages used in various studies were much higher than that used in the present study. The present study shows that even low ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000100014&lng=en&nrm=iso&tlng=en
*  Posterior reversible leukoencephalopathy syndrome (PRES) after kidney transplantation: a case report
Our patient was never exposed to toxic levels of tacrolimus, which prevented us from trying a lower dosage regimen of such drug ... Tacrolimus is a substrate for the P-glycoprotein efflux pump encoded by the multidrug resistance gene-1. Although tacrolimus is ... Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1(MDR1) gene. ... Previous studies have indicated that polymorphisms in drug metabolizing genes could explain the propensity towards ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002018000100091
*  What determines mortality in malignant pheochromocytoma? - Report of a case with eighteen-year survival and review of the...
Although approximately 14 confirmed genes are associated with pheochromocytoma and paraganglioma susceptibility, the genes ... Repeated intermediate-dosage of 131I-MIBG is considered an efficient and well-tolerated treatment in patients with malignant ... Accordingly, it has been shown that only 40% of patients carry germline mutations in the susceptibility genes, and up to two ... The absence of germline mutations in the main predisposing genes suggests that other mechanisms are related to the development ...
http://www.scielo.br/scielo.php?lng=en&script=sci_arttext&pid=S2359-39972018000200264
*  O papel dos produtos finais da glicação avançada (AGEs) no desencadeamento das complicações vasculares do diabetes
... via dos AGEs e via da proteína quinase C-, entre as quais destaca-se a via de formação dos AGEs (2,17). ... estando seu gene localizado no cromossomo 6 no complexo principal de histocompatibilidade entre os genes para as classes II e ... MECANISMOS DE AÇÃO DOS AGEs. Os AGEs podem danificar as células por três mecanismos básicos. O primeiro é a modificação de ... A remoção dos AGEs formados nos componentes teciduais é realizada pela proteólise extracelular ou pelas células scavenger, como ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302008000600005
*  Bioremediation of polyaromatic hydrocarbons (PAHs) using rhizosphere technology
Secondly, isolates can be identified that degrade PAHs but do not contain genes with high homology to known genes implicated in ... It was found to be actively growing over high dosages of phenanthrene with comlete removal of the pollutant in a period of 30 ... Tsuda M, Iino T (1990) Naphthalene degrading genes on plasmid NAH7 are on a defective transposon. Mole Gene Genet 223:34-39. [ ... Shim et al. (2000) introduced the toluene o-monooxygenase genes (TOM) from B. cepacia G4 into several bacteria isolated from ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100007&lng=pt&nrm=iso&tlng=en
*  Green Tea Attenuates Hypotension Induced by Physical Exercise: A Randomized, Placebo Controlled Study
The higher exercise intensity and the presence of allele I of ACE gene elicit a higher post-exercise blood pressure reduction ... other dosages of green tea should be tested, to analyze whether doses lower than 2 g (used in this study) would prevent the ...
http://www.scielo.br/scielo.php?pid=S2359-56472017000400325&script=sci_arttext&tlng=en
*  Oral creatine supplementation attenuates muscle loss caused by limb immobilization: a systematic review
Dosage. Results. Aoki et al. 2004. hind paw, 7 days. Creatine added in the drinking water, ad libitum 5g / kg / day for 3 doses ... The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-51502017000400831&lng=en&tlng=en
*  Efficacy of psychoeducation in bipolar patients: systematic review of randomized trials
Alternatively, differences in the "dosage" and duration of PE between studies or, perhaps more importantly, the individual ... Bipolar disorder likely results from an interplay among multiple genes that interact with environmental and developmental ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000300014&lng=en&nrm=iso&tlng=en
*  Polyunsaturated fatty acids omega-3 supplementation reduces inflammatory markers andimproves insulin action in liver of mice
... compared with other dosages. Thus, this dosage was selected for molecular analysis. This dosage significantly decreased ... 9. Schmoll D, Walker KS, Alessi DR, Grempler R, Burchell A, Guo S, et al. Regulation of glucose6phosphatase gene expression by ... METHODS: Swiss mice were divided into six groups given different dosages of fish oil containing ômega-3 (1mg, 5mg, 10mg and ... RESULTS: The results showed that the dosage of 10mg leads to greater reduction in blood glucose at 14 and 21 days when ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732012000500007&lng=en&nrm=iso&tlng=pt
*  Contracepção hormonal e sistema cardiovascular
The risk of VTE is dependent on the EE dosage. The high dose of EE (, 50 mcg) is associated with a twofold increase in risk of ... Venous thrombosis: the role of genes, environment, and behavior. Hematology Am Soc Hematol Educ Program. 2005; 1-12. [ Links ] ... Hormonal contraceptives are available in various dosage forms and for different routes of administration (oral, intramuscular, ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2011000400021&lng=pt&nrm=iso&tlng=en
*  Post-partum testosterone administration partially reverses the effects of perinatal cadmium exposure on sexual behavior in rats
1999). Cadmium-induced apoptosis and changes in expression of p53, c-jun and MT-I genes in testes and ventral prostate of rats ... performed in the Laboratory of Hormonal Dosages, Department of Animal Reproduction, School of Veterinary Medicine, University ... Lack of functional estrogen receptor beta gene disrupts pubertal male sexual behavior. Hormones and Behavior, 44(5), 427-434 ... regulation of AR gene expression and activity. Endocrinology, 143(1), 263-275. [ Links ]. ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882012000200013
*  Metabolic acidosis and its association with nutritional status in hemodialysis
Albumin dosage was performed by the green bromocresol method.7 Patients with albumin , 4 g/dl were considered malnourished.6 ... The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002015000400458&lng=en&tlng=en
*  Effect of the treatment of Copaifera duckei oleoresin (copaiba) in streptozotocin-induced diabetic rats
Enhanced GLUT 2 gene expression in an oleic acid-induced in vitro fatty liver model. Hepatol. Res. 23, 138-144. [ Links ] ... The glucose dosage was performed using the photocolorimetry glucose-oxidase method (Glucox 500, Doles Reagents and Equipment ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2018000600724&lng=&nrm=iso&tlng=
*  Use of biomarkers in pediatric sepsis: literature review
Regarding to the use of CRP as a diagnostic biomarker, when considered in a single dosage, its sensitivity and specificity are ... 59 Linscheid P, Seboek D, Zulewski H, Keller U, Mülller B. Autocrine/paracrine role of inflammation-mediated calcitonin gene- ... bacterial endotoxins and pro-inflammatory cytokines lead to increased ADM gene expression in several tissues.(59) Furthermore, ... ADM synthesis increases during severe infections because it is a peptide related to the calcitonin gene; and (2) ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-507X2016000400472&lng=en&tlng=en
*  Body composition, resting energy expenditure and inflammatory markers: impact in users of depot medroxyprogesterone acetate...
The blood samples were centrifuged, and serum was immediately stored in small aliquots in a freezer at -80°C. Dosages of ... Variable number of tandem repeat of the 5'-flanking region of type-C human natriuretic peptide receptor gene influences blood ... Human uncoupling protein 2 and 3 genes are associated with obesity in Japanese. Endocrine. 2008;34(1-3):87-95. [ Links ] ...
http://www.scielo.br/scielo.php?lng=en&script=sci_arttext&pid=S2359-39972017000100070