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*  Deletion of the GATA domain of TRPS1 causes an absence of facial hair" by T H. Malik, Stechow D. Von et al.
... and activate transcription. TRPS1, the only other vertebrate protein with the GATA motif, is a large, multitype zinc finger ... GATA transcription factors mediate cell differentiation in diverse tissues, and their dysfunction is associated with certain ... protein that harbors a single DNA-binding GATA domain and represses transcription. Monoallelic TRPS1 mutations cause two ... GATA transcription factors mediate cell differentiation in diverse tissues, and their dysfunction is associated with certain ...
https://mouseion.jax.org/stfb2000_2009/408/
*  GATA6 Antibody | GATA Transcription Factor | Abgent
... or GATA Transcription Factor, manufactured and designed by Abgent, are available for research purposes only. Contact us for a ... GATA6; Transcription factor GATA-6; GATA-binding factor 6. Target/Specificity This Phospho-GATA6-Y271 antibody is generated ... Phospho-GATA6(Y271) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. ... GATA6. Function Transcriptional activator (PubMed:19666519, PubMed:27756709, PubMed:22750565, PubMed:22824924). Regulates ...
http://www.abgent.com/products/AP3766a-Phospho-GATA6Y271-Antibody
*  GATA6 - Transcription factor GATA-6 - Homo sapiens (Human) - GATA6 gene & protein
sp,Q92908,GATA6_HUMAN Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 ... RNA polymerase II transcription factor binding Source: GO_Central. *transcription factor binding Source: UniProtKBInferred from ... RNA polymerase II repressing transcription factor binding Source: Ensembl. *RNA polymerase II transcription factor activity, ... Transcription factor GATA-6Add BLAST. 595. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ...
https://www.uniprot.org/uniprot/Q92908
*  TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data...
... on the long form of the transcription factor GATA6. Phosphorylation of GATA6 on Ser(37) promoted its degradation, thereby ... TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data ... and the growth factors insulin and epidermal growth factor (EGF) to investigate signal integration and transcriptional ... We stimulated colon adenocarcinoma cells with various combinations of the cytokine tumor necrosis factor (TNF) ...
https://www.sigmaaldrich.com/catalog/papers/27273097
*  Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa
... Haveri, Hanna; Westerholm-Ormio ... Both factors were also present in Barrett's esophagus and metaplasia of the stomach. GATA-6 expression was reduced in colon ... We studied in detail the expression patterns of these two GATA factors and a GATA-6 down-stream target, Indian hedgehog (Ihh), ... GATA transcription factors direct cell proliferation and differentiation in many organs, and are implicated in tumorigenesis. ...
http://tampub.uta.fi/handle/10024/65816
*  RePub, Erasmus University Repository: The transcription factor GATA6 is essential for branching morphogenesis and epithelial...
The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal ... Recent loss-of-function studies in mice show that the transcription factor GATA6 is important for visceral endoderm ... GATA6 Transcription Factor, Gene Deletion, Histocytochemistry, In Situ Hybridization, Lung/cytology/*embryology/metabolism, ... The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal ...
https://repub.eur.nl/pub/9590
*  Transcription factor GATA-6
GO Process for Transcription factor GATA-6. positive regulation of transcription from RNA polymerase II promoter 932 ... RNA polymerase II transcription factor activity, sequence-specific DNA binding 174 transcription factor activity, RNA ... This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of ... transcription regulatory region DNA binding 205 transcriptional activator activity, RNA polymerase II transcription regulatory ...
https://pharos.nih.gov/idg/targets/Q92908
*  GATA6 Transcription Factor | Colorado PROFILES
"GATA6 Transcription Factor" by people in this website by year, and whether "GATA6 Transcription Factor" was a major or minor ... "GATA6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH ( ... GATA6 Transcription Factor*GATA6 Transcription Factor. *Transcription Factor, GATA6. *Transcription Factor GATA6 ... Below are the most recent publications written about "GATA6 Transcription Factor" by people in Profiles. ...
https://profiles.ucdenver.edu/display/210151
*  GATA6 GATA binding protein 6 [Homo sapiens (human)] - Gene - NCBI
Title: TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic ... Title: The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients. ... DNA-binding transcription factor activity, RNA polymerase II-specific IMP Inferred from Mutant Phenotype. more info ... DNA-binding transcription factor activity, RNA polymerase II-specific ISA Inferred from Sequence Alignment. more info ...
https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=2627&ordinalpos=2&itool=EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVDocSum
*  Table of Contents - May 09, 2014, 344 (6184) | Science
The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal. By Marcela Rosas, Luke C. Davies, ... Three new studies found that giving old mice blood from young mice-or a factor found in young blood-improved the function of ... Structural Basis for Protein Antiaggregation Activity of the Trigger Factor Chaperone. By Tomohide Saio, Xiao Guan, Paolo Rossi ... A nuclear magnetic resonance study shows how the bacterial chaperone trigger factor can dynamically bind and release many ...
http://science.sciencemag.org/content/344/6184
*  Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics
GATA6 Transcription Factor Regulates Lipid Metabolism in Tissue Resident Macrophages. Opeyemi Stella Ademowo, University of ...
http://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&meetingid=1456
*  GATA4 Mutations Are a Cause of Neonatal and Childhood-Onset Diabetes | Diabetes
The GATA family zinc finger transcription factors GATA4 and GATA6 are known to play important roles in the development of the ... GATA4 is a zinc finger transcription factor closely related to GATA6. Mutations in GATA4 have been described in familial and ... The GATA family of transcription factors, including GATA4 and GATA6, plays important roles in the development of several ... A transcription factor regulatory circuit in differentiated pancreatic cells. Proc Natl Acad Sci U S A 2001;98:14481-14486pmid: ...
http://diabetes.diabetesjournals.org/content/63/8/2888.full
*  The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester | SpringerLink
GATA6 is a zinc finger transcription factor which works in concert with SF-1 [61] to activate steroidogenic enzyme expression ... NR5A1 encodes steroidogenic factor 1 (SF-1), which is a nuclear receptor transcription factor essential for development and ... Maternal smoking was associated with increased levels of the transcription factor GATA6 (P , 0.001; n = 56) in both male and ... its accessory protein MRAP and the key steroidogenic transcription factors NR5A1 and GATA6 were also detectable in all adrenals ...
https://link.springer.com/article/10.1186/s12916-018-1009-7
*  Dissecting direct reprogramming through integrative genomic analysis. - PubMed - NCBI
d, The endodermal transcription factor Gata6 inappropriately lost H3K27me3 and is activated in MCV6 cells. e, The autocrine ... b, The transcription factor Zeb2 is marked by H3K4me3 and expressed in MEFs, but gains H3K27me3 and is silenced in partially ... c, The mesoderm/neural-crest transcription factor Sox9 is marked by H3K4me3 only and remains active in MCV6. ... Somatic cells can be reprogrammed to a pluripotent state through the ectopic expression of defined transcription factors. ...
https://www.ncbi.nlm.nih.gov/pubmed/18509334?access_num=18509334&link_type=MED&dopt=Abstract
*  The interaction of anticancer therapies with tumor-associated macrophages | JEM
The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science. 344:645-648. doi:10.1126/ ... The recent identification of key transcription factors involved in the differentiation of tissue macrophages, such as GATA6 for ... Transcription factors involved in M1 polarization include NF-κB, STAT1, and IRF5 (Krausgruber et al., 2011), whereas IRF4, ... Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine ...
http://jem.rupress.org/content/early/2015/03/03/jem.20150295
*  adenocarcinoma in situ of thyroid 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Expression of GATA-6 was examined in relation to thyroid transcription factor-1 expression, survival, proliferation and ... PURPOSE: Thyroid transcription factor 1 (TTF1) is a transcription factor that regulates the expression of multiple genes ... PAX8 Transcription Factor. Paired Box Transcription Factors. RNA, Messenger / metabolism. RNA, Neoplasm / analysis. Reverse ... PAX8 Transcription Factor; 0 / PAX8 protein, human; 0 / PPAR gamma; 0 / Paired Box Transcription Factors; 0 / RNA, Messenger; 0 ...
http://www.bmlsearch.com/?kwr=adenocarcinoma+in+situ+of+thyroid+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Frontiers | N-acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced...
2012). Transcription factor GATA-6 recruits PPARα to cooperatively activate Glut4 gene expression. J. Mol. Biol. 415, 143-158. ... nuclear factor kappa B (NFKB) activation and the expression of inflammatory genes and Ager (RAGE) propagating the AGE/RAGE axis ... nuclear factor kappa B subunit 1; Rn01399583_m1), Il6 (interleukin 6; Rn01410330_m1), Tnf (tumor necrosis fator; Rn01525859_g1 ... tumor necrosis factor alpha (TNFα) and monocyte chemoattractant protein 1 (MCP-1) rather than the M2 (alternatively activated) ...
https://www.frontiersin.org/articles/10.3389/fphys.2017.00723/full
*  Diversity of Lung Stem and Progenitor Cell Types | SpringerLink
2002). GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. The ... Chen, L., Acciani, T., Le Cras, T., Lutzko, C., & Perl, A. K. (2012b). Dynamic regulation of platelet-derived growth factor ...
https://link.springer.com/chapter/10.1007%2F978-3-319-95279-6_2
*  ESRRB gene - Genetics Home Reference - NIH
Plays a role as transcription factor activator of GATA6, NR0B1, POU5F1 and PERM1 (PubMed:23836911). Plays a role as ... Isoform 1: Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter ... Isoform 3: Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter ... Can coassemble on structured DNA elements with other transcription factors like SOX2, POU5F1, KDM1A and NCOA3 to trigger ESRRB- ...
https://ghr.nlm.nih.gov/gene/ESRRB
*  UniProtKB/SwissProt variant VAR 067384
Transcription factor GATA-6. Gene: GATA6 Chromosomal location: 18q11.1-q11.2 Feedback/Comment? ... GATA6 haploinsufficiency causes pancreatic agenesis in humans. Allen H.L.; Flanagan S.E.; Shaw-Smith C.; De Franco E.; Akerman ...
http://web.expasy.org/variant_pages/VAR_067384.html
*  Trey Westbrook, Ph.D. | People | Houston, Texas
"Control of Alveolar Differentiation by the Lineage Transcription Factors GATA6 and HOPX Inhibits Lung Adenocarcinoma Metastasis ... "A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors." ...
https://www.bcm.edu/people/view/trey-westbrook-ph-d/b26b8e5c-ffed-11e2-be68-080027880ca6
*  GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation. | Sigma-Aldrich
GATA-6 is a zinc-finger transcription factor essential for early embryogenesis. Ablation of GATA-6 in mice impairs endoderm ... GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation.. [Li Rong, Jie Liu ... Last, activation of SMAD1/5 by phosphorylation is significantly inhibited in the absence of GATA-6, and this is reversed by ... Collectively these results suggest that GATA-6 promotes cell survival by regulating endoderm expression of BMP-2 and BM during ...
https://www.sigmaaldrich.com/catalog/papers/22855527
*  Gata4 regulates the formation of multiple organs | Development
... a single transcription factor regulates the formation of many organs. Gata6 is a closely related transcription factor with an ... Koutsourakis, M., Langeveld, A., Patient, R., Beddington, R. and Grosveld, F. (1999). The transcription factor GATA6 is ... Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas. Mol. Cell. Endocrinol. 226,51 - ... Gata factors and early endoderm development. Early endoderm development appears to be normal in both the Gata4 and Gata6 ...
http://dev.biologists.org/content/132/17/4005
*  008875 - B6.129P2-Lgr5|tm1(cre/ERT2)Cle|/J
The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression. Nat Cell ... Transcription factor achaete scute-like 2 controls intestinal stem cell fate. Cell 136(5):903-12. PubMed: 19269367MGI: J:148715 ... Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling. Cancer Cell 31(1):21-34. PubMed: ... Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells. Curr Biol 22(18):1705-10. PubMed: ...
https://www.jax.org/strain/008875