Rescuing biologically relevant consensus regions across replicated samples | BMC Bioinformatics | Full Text
... and HDAC2-GATA1 regulatory networks on rescued regions in K562 cell line. We argue the biological relevance of weak binding ... We observe several master transcription regulators (e.g., SP1 and GATA3) ... GATA1-HDAC2 are among the most enriched transcription factors in MSPC-specific dataset, and are both known to be involved in ... HDAC2-GATA1 rescued regulatory network. For many transcription factors, the biological enrichment of the peaks rescued by MSPC ...
Arena-Idb: a platform to build human non-coding RNA interaction networks | BMC Bioinformatics | Full Text
Guo Z, Maki M, Ding R, Yang Y, Zhang B, Xiong L. Genome-wide survey of tissue-specific microRNA and transcription factor ... LC D, JD A, CO DS, Z Z, X G, JW T, et al.A gata-1- regulated microrna locus essential for erythropoiesis. Proc Natl Acad Sci ... transcription and the corresponding gene. The box on the left side of the image shows the right selection of the transcript ... such as regulation of transcription, RNA processing, nuclear-cytoplasmic transport, translation control and modulation of ...