Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two...
Genetic hearing loss is a common sensory disorder, and its cause is highly heterogeneous. In this study, by targeted next- ... Reestablishing Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells for Hearing Loss 2020. View this ... I. A. Belyantseva, E. T. Boger, and T. B. Friedman, "Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and ... Genetic hearing loss is a common sensory disorder, and its cause is highly heterogeneous. In this study, by targeted next- ...
Long-Standing Motor and Sensory Recovery following Acute Fibrin Sealant Based Neonatal Sciatic Nerve Repair
Sensory-motor recovery was behaviorally studied. Coaptation preserved synaptic covering on lesioned motoneurons and led to ... Brachial plexus lesion results in loss of motor and sensory function, being more harmful in the neonate. Therefore, this study ... acute repair of neonatal peripheral nerves with fibrin sealant results in neuroprotection and regeneration of motor and sensory ... results in significant degeneration of spinal motoneurons as well as sensory neurons present in the dorsal root ganglia. Also, ...
P2X3 Receptor in Primary Afferent Neurons Mediates the Relief of Visceral Hypersensitivity by Electroacupuncture in an...
i,Objective,/i,. To reveal the neurobiological mechanism that P2X,sub,3,/sub, receptor of colonic primary sensory neurons in ... the dorsal root ganglia of the lumbosacral segment is involved in the alleviation of visceral hypersensitivity by EA in an IBS ... L. Y. M. Huang, Y. Gu, and Y. Chen, "Communication between neuronal somata and satellite glial cells in sensory ganglia," Glia ... To reveal the neurobiological mechanism that P2X3 receptor of colonic primary sensory neurons in the dorsal root ganglia of the ...
Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the...
T cells are selectively activated and retained in latently infected sensory ganglia," Immunity, vol. 18, no. 5, pp. 593-603, ...
Obesity and Appetite Control
Cell bodies of afferent fibres of the abdominal vagus nerve are located in the nodose ganglia, which project to the DVC of ... A. DelParigi, K. Chen, A. D. Salbe, E. M. Reiman, and P. A. Tataranni, "Sensory experience of food and obesity: a positron ... G. Burdyga, D. Spiller, R. Morris et al., "Expression of the leptin receptor in rat and human nodose ganglion neurones," ... Transection of all gut sensory vagal fibres results in increased meal size and meal duration, but does not block gastric ...
Autism Research and Treatment | Hindawi
Results from sensory organization test (SOT) or modified clinical test for sensory integration of balance (mCTSIB) found that ... Visual and somatosensory processing deficits, hypotonia, basal ganglia dysfunction, and anxiety are some of the concurrent ... Enhancing motor skills, cerebellum function, and sensory input integration were some of the main mechanisms of these ... Of the children who successfully completed each vestibular test, abnormal responses were observed in 12 (80%) sensory ...
Risk Factors of Fatigue in Idiopathic Parkinson's Disease in a Polish Population
A. Chaudhuri and P. O. Behan, "Fatigue and basal ganglia," Journal of the Neurological Sciences, vol. 179, no. 1-2, pp. 34-42, ... and sensory symptoms have shown that at least one symptom occurs in 88% of the patients with PD, two or more occur in 59%, ... R. Levy and V. Czernecki, "Apathy and the basal ganglia," Journal of Neurology, vol. 253, no. 7, pp. vii54-vii61, 2006. ... Damage to the basal ganglia may affect limbic integration for voluntary actions controlled by the cortex. ...
Quantitative EEG Markers in Mild Cognitive Impairment: Degenerative versus Vascular Brain Impairment
Subscores of 0, 1, 2, and 3 were assigned in basal ganglia for no WMC, 1 focal lesion, more than 1 focal lesion, and confluent ... sensory loss, and gait or balance disturbances. Exclusion criteria were any one of the following: (i) age of 90 years and older ... These lesions in basal ganglia, thalamus, or connecting white matter induce interruption of thalamocortical and striatocortical ... and infratentorial areas and basal ganglia on a 4-point scale. The observer of white matter changes was blind to the clinical ...
Effect of Electroacupuncture on Bladder Dysfunction via Regulation of MLC and MLCK Phosphorylation in a Rat Model of Type 2...
The internal wall of the bladder detrusor smooth muscle is covered by mucosa, which also provides a sensory function to monitor ... The efferent signal from the spinal micturition center is sent to the intramural ganglion of the bladder wall along with the ... the degree of bladder filling and composition of urine [54]. There is evidence that the gain of dynamic sensory structure ...
Pathophysiology of Motor Dysfunction in Parkinson's Disease as the Rationale for Drug Treatment and Rehabilitation
2. The Functional Anatomy and Pathophysiology of the Basal Ganglia and the Role of the Cerebellum. The basal ganglia (BG) ... and abnormalities in peripheral sensory inputs that may influence the response to muscle stretch [83-86]. Studies on spinal ... A. C. Bostan, R. P. Dum, and P. L. Strick, "The basal ganglia communicate with the cerebellum," Proceedings of the National ... H. H. Yin and B. J. Knowlton, "The role of the basal ganglia in habit formation," Nature Reviews Neuroscience, vol. 7, no. 6, ...
Recent Advances in the Endogenous Brain Renin-Angiotensin System and Drugs Acting on It
Pain is defined as hyperexcitation of sensory neurons that arises because of injury, trauma, inflammation, and nerve damage. ... and p44/p42 MAPK activation in the dorsal root ganglia," Pain Medicine (Malden, Mass.), vol. 14, no. 10, pp. 1557-1568, 2013. ... sensory, and motor performances [54, 55]. It increases cholinergic transmission and improves cognitive improvement abilities [ ... such as the basal ganglia, cerebral cortex, and hippocampus [16]. The review explains the recent advances in the brain RAS ...
TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA
E. S. Fernandes, M. A. Fernandes, and J. E. Keeble, "The functions of TRPA1 and TRPV1: moving away from sensory nerves," ... "Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture," British Journal ... inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia," Neuroscience Letters, vol. 228, no. 1, pp. 29-32, 1997. ...
Toxic Effects of Mercury on the Cardiovascular and Central Nervous Systems
C. S. Huang and T. Narahashi, "Mercury chloride modulation of the GABA(A) receptor-channel complex in rat dorsal root ganglion ... sensory disturbance, deafness, blindness, tremors, involuntary movements, mental retardation, coma, and death. Infants whose ... mercury has the ability to increase the permeability of chloride channels of GABA A receptors in the dorsal root ganglion, ...
Taurine Increases Zinc Preconditioning-Induced Prevention of Nitrosative Stress, Metabolic Alterations, and Motor Deficits in...
"The glutamatergic system in primary somatosensory neurons and its involvement in sensory input-dependent plasticity," ... "Histochemical localization of aspartate aminotransferase activity in the hippocampal formation and in peripheral ganglia of the ...
Determination of Polyphenols, Capsaicinoids, and Vitamin C in New Hybrids of Chili Peppers
J. N. Wood, J. Winter, I. F. James, H. Rang, J. Yeats, and S. Bevan, "Capsaicin-induced ion fluxes in dorsal root ganglion ... in sensory receptor membrane [4], evokes pain, and activates autonomic reflexes [5]. Environmental factors and the circumstance ...
GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia
R. Chittajallu and J. T. Isaac, "Emergence of cortical inhibition by coordinated sensory-driven plasticity at distinct synaptic ... Another MRS study reported reduced GABA concentration in basal ganglia but not frontal cortex of schizophrenia patients [237]. ... coordinating incoming sensory and motor information with representations of internal goals and rules to select a context- ... which may occur in any sensory modality but are most commonly auditory and experienced as hearing voices distinct from ones ...