Look up quadruplex in Wiktionary, the free dictionary. Quadruplex may refer to: Quadruplex (New Orleans), a softball complex in ... a four-stranded nucleic acid structure rich in guanine C-quadruplex, a four-stranded nucleic acid structure rich in cytosine, ... found in I-motif DNA Quadruplex, a building split into four apartments, similar to a duplex This disambiguation page lists ... an improvement on the electrical telegraph patented in 1874 by Thomas Edison Two-inch quadruplex videotape, the first practical ...
G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that have been first observed decades ago. Over the ... RNA G-quadruplexes (rG4s): genomics and biological functions Nucleic Acids Res. 2021 Jun 4;49(10):5426-5450. doi: 10.1093/nar/ ... G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that have been first observed decades ago. Over the ...
G-rich sequences have a propensity for forming highly stable quadruplex structures in both RNA and DNA termed G-quadruplexes. G ... Here we show using NMR and CD spectroscopy that the C9orf72 hexanucleotide expansion can form a stable G-quadruplex, which has ... quadruplexes have been shown to be involved in a range of processes including telomere stability and RNA transcription, ... With regards to quadruplex topology, in contrast to DNA G-quadruplexes, RNA G-quadruplexes generally disfavour folded ...
... at Ohio State University and Ilia State University in the country of Georgia have created a method called quadruplex priming ... Isothermal Quadruplex Priming Amplification Moves Closer to Point-of-Care MDx Applications Oct 30, 2014 , Madeleine Johnson ... The QPA reaction is based on formation of "an unusually stable monomolecular quadruplex" by a guanine rich sequence constructed ... These are quenched by neighbor nucleotides until a quadruplex is formed.. Interestingly, unlike other isothermal methods, such ...
Home / Shop / Books / Science and Technology / Chemistry / Biochemistry / G-Quadruplex Structures, Formation and Role in ... Chapter 2. G-Quadruplexes and i-Motifs as Scaffolds for Molecular Engineering of DNA Aptamers. Elena Zavyalova and Alexey ... Chapter Five reviews the historical aspect of how major biological roles of G-quadruplexes have been uncovered by the use of ... Chapter 4. G-Quadruplex-Induced Fluorescence Signal. Rajen Kundu (Department of Chemistry and Biochemistry, University of ...
In this review we summarize the current state of the art in detailing the three main categories of quadruplex-binding ... they fit nicely with the external G-quartets of quadruplexes. Stimulated by the pioneering studies on the cationic porphyrin ... rapidly leading to a large diversity of macrocyclic structures with remarkable-quadruplex binding properties and biological ... Macrocyclic scaffolds are particularly attractive for designing selective G-quadruplex ligands essentially because, on one hand ...
Since G-quadruplexes assemble from certain G-rich single-stranded sequences, they might arise when duplex DNA is unwound such ... These intramolecular G quadruplexes are somewhat dynamic in nature and stabilized by increasing KCl concentrations and ... In this study, single-stranded telomeric templates with the potential to form G-quadruplexes were examined for their effects on ... Our results demonstrate that single-stranded templates containing four telomeric GGG runs fold into intramolecular G-quadruplex ...
607px-Telomere_quadruplex_without_fog. By James Levin , Published December 23, 2013 , Full size is 607 × 599 pixels ...
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We investigated G-quadruplex and i-motif formation in single-stranded DNA and long double-stranded DNA. The promoter region ... Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression. By Yue Li, Junetha Syed, Yuki ... G-quadruplex stabilizers hemin and TMPyP4 reduced the luciferase activity, whereas expression of ATRX led to a recovery in ... Home / KnowledgeBase Articles / Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression ...
We have also compared the melting of inter- and intramolecular quadruplexes. This record has no associated files available for ... We have also compared the melting of inter- and intramolecular quadruplexes. resonance energy-transfer, double-stranded dna, g- ... High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler ... High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler ...
It has been shown that folding singlestranded telomeric DNA into a quadruplex structu ... Stabilisation of G-Quadruplex DNA by Small Molecules. Author(s): Anna Arola and Ramon Vilar Volume 8, Issue 15, 2008 ... Keywords: Quadruplex DNA, telomerase inhibition, oncogene regulation, small molecule Abstract: Guanine-rich sequences of DNA ... This review aims to discuss the different types of ligands that have been recently developed as quadruplex DNA stabilisers. The ...
... Kuželov seminár. Katedra genetiky PriF UK a Katedra biochémie PriF UK v ... Ying and Yang of G-quadruplexes for genome stability. ktora sa uskutocni 1. juna 2021 (utorok) o 16:00 ako webinar: meet.google ... Prírodovedecká fakulta , Aktuality , Kalendár , Kuželove semináre , Kuželove semináre 2021 , Ying and Yang of G-quadruplexes ... 2021/06/01 Ying and Yang of G-quadruplexes for genome stability ...
G-quadruplexes (G4s) are non-canonical secondary structures in nucleic acids that are formed by guanine-rich sequences. G4 ... Biology of RNA G-quadruplexes. Ivanov, Pavel / Brigham and Womens Hospital. NIH 2020. R01 GM. Biology of RNA G-quadruplexes. ... G-quadruplexes (G4S) are extremely stable DNA and RNA secondary structures formed by sequences rich in guanine. RNA G4s are ... G-quadruplexes (G4s) are non-canonical secondary structures in nucleic acids that are formed by guanine-rich sequences. G4 ...
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... a right-handed double helix under physiological conditions but can also form higher-order structures such as a G-quadruplex (G4 ...
Biaryl polyamides as a new class of DNA quadruplex-binding ligands. K.M. Rahman, A.P. Reszka, M. Gunaratnam, Shozeb Haider, P.W ... Biaryl polyamides as a new class of DNA quadruplex-binding ligands. / Rahman, K.M.; Reszka, A.P.; Gunaratnam, M. et al. ... Biaryl polyamides as a new class of DNA quadruplex-binding ligands. In: Chemical Communications. 2009 ; Vol. 27, No. 27. pp. ... Dive into the research topics of Biaryl polyamides as a new class of DNA quadruplex-binding ligands. Together they form a ...
Crystal structure of parallel quadruplexes from human telomeric DNA. dc.contributor.author. Parkinson, GN. ... Telomeric DNA sequences can form four-stranded (quadruplex) structures(2-4), which may be involved in the structure of telomere ... The folding and appearance of the DNA in this intramolecular quadruplex is fundamentally different from the published Na+- ... containing quadruplex structures(2,4,6). All four DNA strands are parallel, with the three linking trinucleotide loops ...
N2 - G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex ... AB - G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex ... G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex formation ... G-quadruplex formation in a DNA template can be assessed using polymerase stop assays, which measure polymerase stalling at G- ...
G-quadruplexes mediate local translation in neurons James P.R. Schofield; James P.R. Schofield 1 ... James P.R. Schofield, Joanne L. Cowan, Mark J. Coldwell; G-quadruplexes mediate local translation in neurons. Biochem Soc Trans ... fragile X mental retardation protein (FMRP), G-quadruplex, heterogeneous nuclear ribonucleoprotein (hnRNP) A2, messenger RNA ( ... There has recently been a huge increase in interest in the formation of stable G-quadruplex structures in mRNAs and their ...
Get editable icons and illustrations of G-quadruplex (hybrid 2). Create professional science figures in minutes with BioRender ... ":"https://icons.biorender.com/w550xh620/5f1f029a9b7b74002845b0cf/g-quadruplex-hybrid-2.png"},{"image":"https://icons.biorender ... w75xh75/5f1f029a9b7b74002845b0ce/g-quadruplex-hybrid-2.png","waterMarkImage":"https://icons.biorender.com/w550xh620/ ... 5f1f029a9b7b74002845b0ce/g-quadruplex-hybrid-2.png"},{"image":"https://icons.biorender.com/w75xh75/5f1f029a9b7b74002845b0cd/g- ...
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Long, K. J. (2018). ,i,c-MYC G-quadruplex DNA structures: Characterization and photocleavage,/i, (Unpublished thesis). Texas ...
Barium in PDB 6tzr: A Dna G-Quadruplex/I-Motif Hybrid. Protein crystallography data. The structure of A Dna G-Quadruplex/I- ... B.Chu, D.Zhang, P.J.Paukstelis. A Dna G-Quadruplex/I-Motif Hybrid. Nucleic Acids Res. 2019. ISSN: ESSN 1362-4962 PubMed: ... The structure of A Dna G-Quadruplex/I-Motif Hybrid also contains other interesting chemical elements:. Bromine. (Br). 2 atoms. ... A full contact list of Barium with other atoms in the Ba binding site number 1 of A Dna G-Quadruplex/I-Motif Hybrid within 5.0Å ...
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Targeting canine c-KIT promoter by a candidate DNA G-quadruplex ligand. GIANTIN, MERY;ZORZAN, ELEONORA;DA ROS, SILVIA;Zorro ... Introduction G-quadruplexes (G-quad) are DNA secondary structures formed by stacked G-tetrads frequently located in telomeres ... Introduction G-quadruplexes (G-quad) are DNA secondary structures formed by stacked G-tetrads frequently located in telomeres ... Comparative studies about the efficacy of this and other G-quad ligands in blocking human kit G-quadruplex are currently ...