Quadruplex - Wikipedia
Look up quadruplex in Wiktionary, the free dictionary. Quadruplex may refer to: Quadruplex (New Orleans), a softball complex in ... a four-stranded nucleic acid structure rich in guanine C-quadruplex, a four-stranded nucleic acid structure rich in cytosine, ... found in I-motif DNA Quadruplex, a building split into four apartments, similar to a duplex This disambiguation page lists ... an improvement on the electrical telegraph patented in 1874 by Thomas Edison Two-inch quadruplex videotape, the first practical ...
RNA G-quadruplexes (rG4s): genomics and biological functions
G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that have been first observed decades ago. Over the ... RNA G-quadruplexes (rG4s): genomics and biological functions Nucleic Acids Res. 2021 Jun 4;49(10):5426-5450. doi: 10.1093/nar/ ... G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that have been first observed decades ago. Over the ...
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G...
G-rich sequences have a propensity for forming highly stable quadruplex structures in both RNA and DNA termed G-quadruplexes. G ... Here we show using NMR and CD spectroscopy that the C9orf72 hexanucleotide expansion can form a stable G-quadruplex, which has ... quadruplexes have been shown to be involved in a range of processes including telomere stability and RNA transcription, ... With regards to quadruplex topology, in contrast to DNA G-quadruplexes, RNA G-quadruplexes generally disfavour folded ...
Isothermal Quadruplex Priming Amplification Moves Closer to Point-of-Care MDx Applications | GenomeWeb
... at Ohio State University and Ilia State University in the country of Georgia have created a method called quadruplex priming ... Isothermal Quadruplex Priming Amplification Moves Closer to Point-of-Care MDx Applications Oct 30, 2014 , Madeleine Johnson ... The QPA reaction is based on formation of "an unusually stable monomolecular quadruplex" by a guanine rich sequence constructed ... These are quenched by neighbor nucleotides until a quadruplex is formed.. Interestingly, unlike other isothermal methods, such ...
G-Quadruplex Structures, Formation and Role in Biology - Nova Science Publishers
Home / Shop / Books / Science and Technology / Chemistry / Biochemistry / G-Quadruplex Structures, Formation and Role in ... Chapter 2. G-Quadruplexes and i-Motifs as Scaffolds for Molecular Engineering of DNA Aptamers. Elena Zavyalova and Alexey ... Chapter Five reviews the historical aspect of how major biological roles of G-quadruplexes have been uncovered by the use of ... Chapter 4. G-Quadruplex-Induced Fluorescence Signal. Rajen Kundu (Department of Chemistry and Biochemistry, University of ...
"One Ring to Bind Them All"-Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA...
In this review we summarize the current state of the art in detailing the three main categories of quadruplex-binding ... they fit nicely with the external G-quartets of quadruplexes. Stimulated by the pioneering studies on the cationic porphyrin ... rapidly leading to a large diversity of macrocyclic structures with remarkable-quadruplex binding properties and biological ... Macrocyclic scaffolds are particularly attractive for designing selective G-quadruplex ligands essentially because, on one hand ...
Intramolecular Telomeric G-Quadruplexes Dramatically Inhibit DNA Synthesis by Replicative and Translesion Polymerases,...
Since G-quadruplexes assemble from certain G-rich single-stranded sequences, they might arise when duplex DNA is unwound such ... These intramolecular G quadruplexes are somewhat dynamic in nature and stabilized by increasing KCl concentrations and ... In this study, single-stranded telomeric templates with the potential to form G-quadruplexes were examined for their effects on ... Our results demonstrate that single-stranded templates containing four telomeric GGG runs fold into intramolecular G-quadruplex ...
607px-Telomere quadruplex without fog | Yang-Sheng.com
quadruplex Archives * RealtyBizNews: Real Estate Marketing & Beyond
Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression - JASCO
We investigated G-quadruplex and i-motif formation in single-stranded DNA and long double-stranded DNA. The promoter region ... Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression. By Yue Li, Junetha Syed, Yuki ... G-quadruplex stabilizers hemin and TMPyP4 reduced the luciferase activity, whereas expression of ATRX led to a recovery in ... Home / KnowledgeBase Articles / Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression ...
High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler -...
We have also compared the melting of inter- and intramolecular quadruplexes. This record has no associated files available for ... We have also compared the melting of inter- and intramolecular quadruplexes. resonance energy-transfer, double-stranded dna, g- ... High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler ... High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler ...
Stabilisation of G-Quadruplex DNA by Small Molecules | Bentham Science
It has been shown that folding singlestranded telomeric DNA into a quadruplex structu ... Stabilisation of G-Quadruplex DNA by Small Molecules. Author(s): Anna Arola and Ramon Vilar Volume 8, Issue 15, 2008 ... Keywords: Quadruplex DNA, telomerase inhibition, oncogene regulation, small molecule Abstract: Guanine-rich sequences of DNA ... This review aims to discuss the different types of ligands that have been recently developed as quadruplex DNA stabilisers. The ...
Ying and Yang of G-quadruplexes for genome stability
... Kuželov seminár. Katedra genetiky PriF UK a Katedra biochémie PriF UK v ... Ying and Yang of G-quadruplexes for genome stability. ktora sa uskutocni 1. juna 2021 (utorok) o 16:00 ako webinar: meet.google ... Prírodovedecká fakulta , Aktuality , Kalendár , Kuželove semináre , Kuželove semináre 2021 , Ying and Yang of G-quadruplexes ... 2021/06/01 Ying and Yang of G-quadruplexes for genome stability ...
Biology of RNA G-quadruplexes - Pavel Ivanov
G-quadruplexes (G4s) are non-canonical secondary structures in nucleic acids that are formed by guanine-rich sequences. G4 ... Biology of RNA G-quadruplexes. Ivanov, Pavel / Brigham and Womens Hospital. NIH 2020. R01 GM. Biology of RNA G-quadruplexes. ... G-quadruplexes (G4S) are extremely stable DNA and RNA secondary structures formed by sequences rich in guanine. RNA G4s are ... G-quadruplexes (G4s) are non-canonical secondary structures in nucleic acids that are formed by guanine-rich sequences. G4 ...
Palm Breeze Drive Quadruplex
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G-quadruplex Archives | IonOpticks
Biaryl polyamides as a new class of DNA quadruplex-binding ligands<...
Biaryl polyamides as a new class of DNA quadruplex-binding ligands. K.M. Rahman, A.P. Reszka, M. Gunaratnam, Shozeb Haider, P.W ... Biaryl polyamides as a new class of DNA quadruplex-binding ligands. / Rahman, K.M.; Reszka, A.P.; Gunaratnam, M. et al. ... Biaryl polyamides as a new class of DNA quadruplex-binding ligands. In: Chemical Communications. 2009 ; Vol. 27, No. 27. pp. ... Dive into the research topics of Biaryl polyamides as a new class of DNA quadruplex-binding ligands. Together they form a ...
Crystal structure of parallel quadruplexes from human telomeric DNA
Crystal structure of parallel quadruplexes from human telomeric DNA. dc.contributor.author. Parkinson, GN. ... Telomeric DNA sequences can form four-stranded (quadruplex) structures(2-4), which may be involved in the structure of telomere ... The folding and appearance of the DNA in this intramolecular quadruplex is fundamentally different from the published Na+- ... containing quadruplex structures(2,4,6). All four DNA strands are parallel, with the three linking trinucleotide loops ...
Predicting G-quadruplexes from DNA sequences using multi-kernel convolutional neural networks<...
N2 - G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex ... AB - G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex ... G-quadruplexes are nucleic acid secondary structures that form within guanine-rich DNA or RNA sequences. G-quadruplex formation ... G-quadruplex formation in a DNA template can be assessed using polymerase stop assays, which measure polymerase stalling at G- ...
G-quadruplexes mediate local translation in neurons | Biochemical Society Transactions | Portland Press
G-quadruplexes mediate local translation in neurons James P.R. Schofield; James P.R. Schofield 1 ... James P.R. Schofield, Joanne L. Cowan, Mark J. Coldwell; G-quadruplexes mediate local translation in neurons. Biochem Soc Trans ... fragile X mental retardation protein (FMRP), G-quadruplex, heterogeneous nuclear ribonucleoprotein (hnRNP) A2, messenger RNA ( ... There has recently been a huge increase in interest in the formation of stable G-quadruplex structures in mRNAs and their ...
Free G-quadruplex (hybrid 2) Icons, Symbols & Images | BioRender
Get editable icons and illustrations of G-quadruplex (hybrid 2). Create professional science figures in minutes with BioRender ... ":"https://icons.biorender.com/w550xh620/5f1f029a9b7b74002845b0cf/g-quadruplex-hybrid-2.png"},{"image":"https://icons.biorender ... w75xh75/5f1f029a9b7b74002845b0ce/g-quadruplex-hybrid-2.png","waterMarkImage":"https://icons.biorender.com/w550xh620/ ... 5f1f029a9b7b74002845b0ce/g-quadruplex-hybrid-2.png"},{"image":"https://icons.biorender.com/w75xh75/5f1f029a9b7b74002845b0cd/g- ...
'DNA G-quadruplex: Structure, Function, and Drug...
Advantage X - Quadruplex Industrial Vacuum System Archives - Becker Pumps
c-MYC G-Quadruplex DNA Structures: Characterization and Photocleavage
Long, K. J. (2018). ,i,c-MYC G-quadruplex DNA structures: Characterization and photocleavage,/i, (Unpublished thesis). Texas ...
FTMB-Metal-SM-SCA Series (Quadruplex Adapter) | Eight Limited
Barium in PDB 6tzr: A Dna G-Quadruplex/I-Motif Hybrid
Barium in PDB 6tzr: A Dna G-Quadruplex/I-Motif Hybrid. Protein crystallography data. The structure of A Dna G-Quadruplex/I- ... B.Chu, D.Zhang, P.J.Paukstelis. A Dna G-Quadruplex/I-Motif Hybrid. Nucleic Acids Res. 2019. ISSN: ESSN 1362-4962 PubMed: ... The structure of A Dna G-Quadruplex/I-Motif Hybrid also contains other interesting chemical elements:. Bromine. (Br). 2 atoms. ... A full contact list of Barium with other atoms in the Ba binding site number 1 of A Dna G-Quadruplex/I-Motif Hybrid within 5.0Å ...
IEC60502 Aerial Bundled Cable XLPE insulated Quadruplex Service Drop Wire
Targeting canine c-KIT promoter by a candidate DNA G-quadruplex ligand
Targeting canine c-KIT promoter by a candidate DNA G-quadruplex ligand. GIANTIN, MERY;ZORZAN, ELEONORA;DA ROS, SILVIA;Zorro ... Introduction G-quadruplexes (G-quad) are DNA secondary structures formed by stacked G-tetrads frequently located in telomeres ... Introduction G-quadruplexes (G-quad) are DNA secondary structures formed by stacked G-tetrads frequently located in telomeres ... Comparative studies about the efficacy of this and other G-quad ligands in blocking human kit G-quadruplex are currently ...