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*  Frontiers | Molecular Recognition of Gangliosides and Their Potential for Cancer Immunotherapies | Immunology
In this review, we describe how proteins recognize gangliosides, focusing on the molecular recognition of gangliosides ... In this review, we describe how proteins recognize gangliosides, focusing on the molecular recognition of gangliosides ... Gangliosides perform important functions through carbohydrate-specific interactions with proteins, for example as receptors in ... Gangliosides perform important functions through carbohydrate-specific interactions with proteins, for example as receptors in ...
https://www.frontiersin.org/articles/10.3389/fimmu.2014.00325/full
*  1,4-alpha-D-glucan maltotriohydrolase - WikiVisually
3. The mechanism of the hydrolysis of a G M2 ganglioside and removal of a GalNAc residue to produce G M3 ganglioside. ... 2. Hydrolysis of G M2 ganglioside to G M3 ganglioside catalyzed by hexosaminidase A. ... It may play a role in modulating the ganglioside content of the lipid bilayer, NEU3 has been shown to interact with Grb2 ... It is localized in the membrane, and its activity is specific for gangliosides. It may play a role in modulating the ...
https://wikivisually.com/wiki/1%2C4-alpha-D-glucan_maltotriohydrolase
*  MEDICA
Promotion of neuritogenesis in mouse neuroblastoma cells by ganglioside GM3: involvement of three signal pathways ... G(M3) Ganglioside;Neuroblastoma;Academic Dissertations. * 1989. * * * Effects of direct autonomic nerve stimulation on the cat ...
http://digital.library.musc.edu/cdm/search/searchterm/unstimulated
*  MEDICA
Promotion of neuritogenesis in mouse neuroblastoma cells by ganglioside GM3: involvement of three signal pathways ... G(M3) Ganglioside;Neuroblastoma;Academic Dissertations. * 1989. * * * Phosphodiesterase inhibition and adenosine A (subscript ...
http://digital.library.musc.edu/cdm/search/searchterm/coupled
*  Justin L. Sonnenburg | Stanford Medicine Profiles
While pursuing this, we found that alpha2-3-linked Neu on chemically de-N-acetylated G(M3) ganglioside resists acid hydrolysis ... De-N-acetyl-gangliosides in humans: Unusual subcellular distribution of a novel tumor antigen CANCER RESEARCH Chammas, R., ... Unsubstituted Neu is thought to occur on native gangliosides of certain tumors and cell lines, and synthetic de-N-acetyl- ... Characterization of the acid stability of glycosidically linked neuraminic acid - Use in detecting de-N-acetyl-gangliosides in ...
https://med.stanford.edu/profiles/justin-sonnenburg
*  Inhibition of GM2 and GD3 Synthase of End-Product Gangliosides in Vitro | Springer for Research & Development
... on the activities of two key enzymes in ganglioside biosynthesis, namely GM2 synthase and GD3synthase in rat liver Golgi ... The effect of end-product gangliosides (GD1a,GT1b, GQ1b) ... At all GM3 concentrations gangliosides GD1a, GT1b, and GQ1b ... The effect of end-product gangliosides (GD1a,GT1b, GQ1b) on the activities of two key enzymes in ganglioside biosynthesis, ... the activity reached a maximum at GM3 concentration of 80 µM and came sharply down with increasing concentration of GM3. ...
https://rd.springer.com/chapter/10.1007/978-3-642-71932-5_25
*  HEXA - Wikipedia
... amino acids that cause the formation of the loop allow the alpha subunit to hydrolyze GM2 gangliosides into GM3 gangliosides by ... People with Tay-Sachs disease are unable to remove the GalNAc residue from the GM2 ganglioside, and as a result, they end up ... Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules ... The alpha subunit can hydrolyze GM2 gangliosides because it contains a loop structure consisting of the amino acids: Gly-280, ...
https://en.m.wikipedia.org/wiki/HEXA
*  NAVER Academic > Search...
Animals, Cattle, Ceramides, G(M1) Ganglioside, G(M3) Ganglioside, Gangliosides, Glycosphingolipids, Mathematics, ... Molecular parameters and physical state of neutral glycosphingolipids and gangliosides in monolayers at different temperatures. ...
https://academic.naver.com/search.naver?field=3&query=Biochimica+et+Biophysica+Acta+854%EA%B6%8C+2%ED%98%B8
*  List of MeSH codes (D09) - Wikipedia
... ganglioside MeSH D09.400.410.420.025.475.400 --- g(m2) ganglioside MeSH D09.400.410.420.025.475.510 --- g(m3) ganglioside MeSH ... gangliosides MeSH D09.400.410.420.025.475.390 --- g(m1) ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D09)
*  List of MeSH codes (D10) - Wikipedia
... ganglioside MeSH D10.390.470.025.475.400 --- g(m2) ganglioside MeSH D10.390.470.025.475.510 --- g(m3) ganglioside MeSH D10.390. ... ganglioside MeSH D10.570.877.360.025.475.400 --- g(m2) ganglioside MeSH D10.570.877.360.025.475.510 --- g(m3) ganglioside MeSH ... gangliosides MeSH D10.570.877.360.025.475.390 --- g(m1) ... gangliosides MeSH D10.390.470.025.475.390 --- g(m1) ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D10)
*  Markers of sympathetic nervous system activity associate with complex plasma lipids in metabolic syndrome subjects<...
GM3 ganglioside, sphingomyelin, phosphatidylcholine, alkyl- and alkenylphosphatidylcholine, phosphatidylinositol and free ... GM3 ganglioside, sphingomyelin, lysophosphatidylcholine, phosphatidylinositol, lysophosphatidylinositol and free cholesterol. ... N2 - Background and aims Plasma sphingolipids including ceramides, and gangliosides are associated with insulin resistance (IR ... AB - Background and aims Plasma sphingolipids including ceramides, and gangliosides are associated with insulin resistance (IR ...
https://research.monash.edu/en/publications/markers-of-sympathetic-nervous-system-activity-associate-with-com
*  NAVER Academic > Search...
M3) Ganglioside, Gangliosides, isolation &... ... Gangliosides as diagnostic markers of human astrocytomas and ... Adult, Aged, Astrocytoma, metabolism, pathology, Brain Neoplasms, Female, G(M1) Ganglioside, analogs & derivatives, analysis, G ...
https://academic.naver.com/search.naver?field=3&query=Cancer+74%EA%B6%8C+11%ED%98%B8&page=3
*  Synthetic Sphingolipids as Bioactive Molecules: Roles in Regulation of Cell Function - CHEMICAL BIOLOGY
... four in GM1 and two in GM3. GM3 is the principal ganglioside found in human T lymphocytes. GM1 is a principal ganglioside in ... Figure 5. The structures of (1) glycosphingolipids and (2) the gangliosides GM3 and GM1. GM3 contains ceramide, one glucose ... Ganglioside GM3 binds to insulin receptors; in fact, the accumulation of GM3 in membrane microdomains (rafts) of adipocytes ... Figure 5 shows the structures of the gangliosides GM1 and GM3. In ganglioside nomenclature, the subscript letter "M" refers to ...
http://schoolbag.info/chemistry/chemical_biology/156.html
*  楯 真一(大学院理学研究科)
TISSUE ACCUMULATION OF SULFATIDE AND G(M3) GANGLIOSIDE IN A PATIENT WITH VARIANT FARBER-DISEASE, CLINICA CHIMICA ACTA, 234巻, pp ... NOVEL GANGLIOSIDES CONTAINING THE SIALYL-LE(A) STRUCTURE FROM A HUMAN RECTAL ADENOCARCINOMA, JOURNAL OF BIOLOGICAL CHEMISTRY, ...
http://seeds.office.hiroshima-u.ac.jp/profile/ja.675e3840f2d38097520e17560c007669.html
*  TREATMENT OF CNS DISORDERS ASSOCIATED WITH MUTATIONS IN GENES ENCODING LYSOSOMAL ENZYMES - Patent application
GM2 and GM3 gangliosides, accumulated in the same neurons, but were consistently located in separate populations of cytoplasmic ... gangliosides). Accumulation of gangliosides can results in dystonia and parkinsonism in humans (Roze et al., Movement Disorders ... 2003; 14(4):551-4. Such accumulation of gangliosides can also lead to α-synuclein accumulation, as well as neuronal death ... 2005; 20(10): 1366-1369). A mouse model that accumulates GM2 ganglioside also accumulated α-synuclein (Suzuki et al., ...
http://www.patentsencyclopedia.com/app/20110105560
*  n-Butyrate Mediation of Ganglioside Expression of Human and Murine Cancer Cells Demonstrates Relative Cell Specificity |...
... n-butyrate did not mediate expression of all gangliosides and specifically did not mediate expression of GM3. This effect ... 2. Because of the importance of gangliosides in cancer pathogenesis, we investigated the effects of n-butyrate on ganglioside ... Gangliosides are amphipathic, sialylated glycosphingolipids that undergo profound changes in many transformed cells and may ... n-Butyrate Mediation of Ganglioside Expression of Human and Murine Cancer Cells Demonstrates Relative Cell Specificity. Charles ...
http://www.clinsci.org/content/88/4/491
*  Preparation of radioactive Tay-Sachs ganglioside labeled in the sialic acid moiety - Request PDF
Preparation of radioactive Tay-Sachs ganglioside labeled in the sialic acid moiety ... Aubin, Y.; Ito, Y.; Paulson, J.C.; Prestegard, J.H., 1993: Structure and dynamics of the sialic acid moiety of G-M3-ganglioside ... Quirk J.M.; Tallman J.F.; Brady R.O., 1972: The preparation of tri hexosyl ganglioside and tetra hexosyl ganglioside ... Tallman, J.F.; Kolodny, E.H.; Brady, R.O., 1975: The preparation of Tay-Sachs ganglioside specifically labeled in either the N- ...
https://eurekamag.com/research/044/014/044014927.php
*  Uperin elisa and antibody
Ganglioside M3 Antibody (GM3) ELISA Kit. • Intrinsic Factor Antibody (IF) ELISA Kit. • Matrix Metalloproteinase 28 (MMP-28) ...
https://www.mybiosource.com/protein_family.php?root=uperin
*  Paternally-expressed gene 3 protein elisa and antibody
Anti-Ganglioside M3 Antibody (GM3) ELISA Kit. • Interleukin-1 receptor type 1 (IL1R1) Recombinant Protein. • W-3 Unsaturated ...
https://www.mybiosource.com/protein_family.php?root=paternally-expressed-gene-3-protein
*  Normal
Cell cycle analysis by FACS indicated that EAC-cell associated gangliosides and its anti-idiotype antibody were acting both at ... the M2 i.e. S and M3 i.e. G2/M phases of the cell cycle to arrest tumor growth. ... Inhibition of subcutaneous growth of Ehrlich ascites carcinoma (EAC) tumor by post-immunization with EAC-cell gangliosides and ... Inhibition of subcutaneous growth of Ehrlich ascites carcinoma (EAC) tumor by post immunization with EAC-cell gangliosides and ...
https://www.niscair.res.in/sciencecommunication/ResearchJournals/rejour/ijeb/ijeb2k11/ijeb_aug11.asp
*  Muscarinic (M3) Receptors - Checkpoint Kinase in Cell biology
Muscarinic (M3) Receptors • biospraysehatalami The curative ramifications of monosialotetrahexosyl ganglioside (GM1) in the ... Muscarinic (M3) Receptors • biospraysehatalami Background HIV-1 infection of target cells is normally mediated the binding from ... Muscarinic (M3) Receptors • biospraysehatalami Objective: This research was completed to judge the efficacy of Ormeloxifene in ... Muscarinic (M3) Receptors • biospraysehatalami For several years, there's been speculation about the good thing about ...
http://biospraysehatalami.com/category/muscarinic-m3-receptors/
*  Ingredient Information
Photochemical labeling of human erythrocyte membrane proteins with radioiodinated 4-azidosalicylic acid derivatives of G(M3), G ... D3), G(M1), and FucG(M1) gangliosides.. Acta Biochim Pol. impact factor: .569. 1998; 45(2): 509-21. 340: Font WF.. Parasites in ...
http://sw16.im.med.umich.edu/chmis-c/ingredient/showIngredient.jsp?ID=65
*  Lenti-GD2 CAR (scFv-b2c-CD3ζ, ch14.18) Viral Particle vector - Creative Biolabs
GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G ... GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of ...
https://www.creative-biolabs.com/car-t/lenti-gd2-car-scfv-b2c%CE%B6-ch14-18-vp-2737.htm
*  B4GALNT1 rabbit monoclonal antibody - (H00002583-K) - Products - Abnova
GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G ... GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of ...
http://www.abnova.com/products/products_detail.asp?catalog_id=H00002583-K
*  Influence of Serum and Hypoxia on Incorporation of [(14)C]-D-Glucose or [(14)C]-L-Glutamine into Lipids and Lactate in Murine...
U-L-glutamine to examine the profile of de novo lipid biosynthesis in the VM-M3 murine glioblastoma cells. The major lipids ... and gangliosides. Endogenous lipid synthesis, using either glucose or glutamine, was greater in media without fetal bovine ... and that the VM-M3 glioblastoma cells could acquire lipids, especially cholesterol, from the external environment for growth ...
https://www.ncbi.nlm.nih.gov/pubmed/26537505