Bead-level comparisons found many DEPs within sample pairs, but most (73%) were ,2-fold changed. There was no consistent ... Effect of long-term storage in TRIzol on microarray-based gene expression profiling. / Ma, Wencai; Wang, Michael; Wang, Zhi ... Effect of long-term storage in TRIzol on microarray-based gene expression profiling. In: Cancer Epidemiology Biomarkers and ... Effect of long-term storage in TRIzol on microarray-based gene expression profiling. Cancer Epidemiology Biomarkers and ...

Fold Change Classifiers for the Analysis of Gene Expression Profiles. In Gaul W, Geyer-Schulz A, Baba Y, Okada A, (eds.), ... Barth TFE, Kraus JM, Lausser L, Flossbach L, Schulte L, Holzmann K, Kestler HA, Möller P. Comparative gene-expression profiling ... Semantic multi-classifier systems for the analysis of gene expression profiles. Archives of Data Science Series A 1(1), 157-176 ... Semantic multi-classifier systems for the analysis of gene expression profiles. In Proceedings of the GPSDAA 2013 Symposium in ...

... a customizable website created from your institutions existing Pivot profiles that instantly brings your researchers and their ... Our research is focused on how cells recognize stress and induce gene expression pathways to alleviate damage. ... including nutrient deprivation and disruptions in protein folding. This research identified stress recognition pathways, gene ... Edit ProfileView information about editing profiles.. You must login to Pivot in order to edit your profile.. Login or create ...

... expression, adjusted p value ≤5%). Among them, about 60 genes have a modulated expression of a fold increase greater than 2 ( ... C, F) Gene expression profiles of FACS sorted NK cells (NK1.1+, NKp46+, CD3-) were generated using RNA-sequencing. (C) A ... Gene expression: blue=downregulated, red=upregulated. (D) Heatmap showing results of gene ontology analysis for genes in Cish ... We next compared the gene expression profiles of Cish+/+Ncr1iCre vs Cishfl/flNcr1iCre NK cells. Cells from spleen were purified ...

An increase in LUM gene expression was observed in OA cartilage from the medial part of the humeral condyle. Histopathological ... Median (and interquartile ranges) relative gene expression profiles select genes in articular cartilage (A) and SCB (B) from ... The median relative expression of genes evaluated in normal and OA feline cartilage and SCB, interquartile ranges (IQR), fold ... The results of the gene expression profiles are illustrated in Figure 1A and 1B, and Additional file 2. In OA cartilage from ...

Traditional approaches for biomarker discovery calculate the fold change for each gene, comparing expression profiles between ... First, we developed a machine learning pipeline that takes lncRNA expression profiles of cancer samples as input and outputs a ... However, transcriptomic data is high dimensional, and finding the best subset of genes (features) related to causing cancer is ... tumor and healthy samples, thus failing to capture the combined effect of the whole gene set. Also, these approaches do not ...

... while the expression levels of more than 625 genes were down regulated (2-7 fold). The differentially expressed genes can be ... Title: Transcriptional profiling of chicken gene expression during cytolytic infection of Mareks disease virus Author. Heidari ... Transcriptional profiling of chicken gene expression during cytolytic infection of Mareks disease virus [abstract]. 8th ... In this study, we conducted a comprehensive chicken gene expression profiling using oligonucleotide-based Affymetrix GeneChip ...

... to support multipurpose analysis of genome-wide genetic variation and gene expression profile across multiple phenotypes ... Results are presented as fold change over control condition SCR, the average profiles of the 4 normalizations are shown. ... gene variation, gene expression, HIV latency and the identification of a specific cell surface biomarker expressed by HIV ... including gene variants, splice variants, expression in resting CD4+ T cells, expression in TCR-activated cells, time of ...

METHODS: Microarray-based gene expression profiling data from BPD was employed to identify differentially expressed genes. A ... fold-change > 2). Co-location (cis) and co-expression (trans) prediction revealed 14 differentially expressed target genes ( ... positively affected the mRNA expression levels of apoptotic genes (BAD, BID, BTK, TP53, and TP53I3) and mitochondrial genes ( ... MSTRG.8869.3 and MSTRG.6723.5 expressions affect oocyte development after vitrification by regulating target gene expressions. ...

The elucidation of the cell biology of the secretory machinery is of great importance, as it drives protein expression for ... the expression profiles are highly similar (or inverse) to the protein folding genes. Thus both proteins could be potential ... c Gene expression levels across all samples within genes with the functional annotation protein folding. d Gene expression ... a Expression profile of correlated gene Rbbp7 (red) across all mouse samples visualised with the expression profiles of Fig. 2c ...

The ITGB4 gene is mapped on 17q25.1. Using expression profiling, Yang et al. found that ITGB4 was upregulated 6-fold by ZKSCAN3 ... The ITGB4 gene is mapped on 17q25.1. Using expression profiling, Yang et al. found that ITGB4 was upregulated 6-fold by ZKSCAN3 ... and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a ... and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor ...

... and senescence-associated secretory profile were evaluated. Chronic exposure to IL-1β induces only partial expression of ... and expression of some SASP components. Etoposide-induced senescence model may help investigate the initiation of cellular ... Several hallmarks of cellular senescence, such as cell cycle arrest, expression of cyclin-dependent kinase inhibitors, DNA ... 99.49-fold change), COX-2 (74.97-fold change), and iNOS (4810.8-fold change) (Figure 5A). Only PAI-1 gene expression was ...

... consecutively included patients during the first peak of the COVID-19 epidemic in Brazil and analyzed the expressions of genes ... Co-infection was associated with increased IL-6 (P = 0.043) and IL-12B (P = 0.017) expression. The median disability grades ... Fold-changes in the gene expression of TNF-α, IL-10, IL-1β, IL-8, IL-6, IL-12, and IL-12B and the adjusted effects of COVID-19 ... The number of previous bacille Calmette-Guerin (BCG) vaccine doses was not related to the gene expression profiles. No patients ...

... gene expression, RNA viruses, and disease.. Tullman-Ercek published a paper in ACS Synthetic Biology about a new platform for ... "This center will raise our leadership profile in the field rapidly," says Milan Mrksich, Henry Wade Rogers Professor of ... Lucks developed a new technology that can take a nucleotide- resolution snapshot of RNA folding during synthesis. Published in ... Members of the community published several high-profile papers in high-impact journals. ...

First, we filtered the gene list of CIBERSORT (see their supplement 2). A 1.5-fold change cutoff from the highest expression ... We annotated genes located in copy-number peaks with the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathways. ... The high expression of one costimulator in cluster 3, TNFSF8 (mean log2 fold change relative to the paired normal tissue, 0.05 ... B, Log2-fold change in mRNA expression in the tumor site relative to the paired normal tissue and log2 ratio of copy-number ...

... gene microarray data of BMSCs and GSE72088 gene microarray data of primary hepatocytes were obtained from the Gene Expression ... The expression of the hub genes in the BMSCs and hepatocytes was verified by reverse transcription-quantitative PCR (RT-qPCR). ... Hub genes were analyzed using the STRING and Cytoscape v 3.8.2, revealing that twenty-four hub genes, play a pivotal role in ... Herein, we screened differentially expressed genes between hepatocytes and untreated BMSCs to identify the genes responsible ...

Gene-expression profiling showed that both the DEP extract and ox-PAPC co-regulated a large number of genes. Using network ... Diesel exhaust particles and oxidized phospholipids synergistically affect the expression profile of several gene modules that ... These modules were also enriched in synergistically co-regulated genes and pathways relevant to vascular inflammation. We ... analysis to identify coexpressed gene modules, we found three modules that were most highly enriched in genes that were ...

... upregulation increased from 30-fold at Day 30 to 45-fold at Day 14. The EASE analysis yielded eight functional classes of gene ... The expression of selected genes was quantified using real-time polymerase chain reaction. Functional clustering was performed ... The lists of up- and downregulated genes were cross-matched with lists of genes known to be associated with cytokines or the ... A total of 1109 genes were significantly changed from reference time zero during the time course: CXCL14, which produces a ...

... representing five mRNA folding profiles and three codon usage profiles. Fluorescence signals produced by the expression of ... To validate these findings, a synthetic library of 15 synonymous iLOV genes was created, ... Protein-coding genes in T. vaginalis are largely controlled by two core promoter elements, producing mRNAs with short 5′ UTRs. ... these synonymous iLOV genes in T. vaginalis were consistent with and validated our in silico predictions. This study ...

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. Rna. 2005; 11: 241-247 ... 2 fold change). Statistical analysis was performed by comparing the normalized expression of miRNAs in glaucomatous and control ... miRNA expression has been suggested to occur in a coordinated manner with that of the host gene mRNA.20 The miR-143 gene is ... High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Res. 2008; 36: ...

Chromatin Structure, Gene expression, Nuclear Architecture. We are interested in how 10 and 30 nm chromatin fibers fold into ... Edit Your Profile. Professor of Cell & Developmental Biology. Professor of Biophysics and Quantitative Biology ... Nuclear speckle contact amplifies gene expression Recent work from the Laboratory in Cell and Developmental Biology was ... Kim, J., Khanna, N., A.S. Belmont, Gene expression amplification by nuclear speckles, JCB (2020) 219 (1): e201904046, doi: ...

The real-time RT-PCR was used to verify the altered expression of selected genes by PPARs and we found that these genes were ... it was noted that while ligand-activated PPARδ induced target gene expression, unliganded PPARδ repressed these genes. ... The expression of each introduced PPAR gene was investigated using the various concentrations of doxycycline in the culture ... human hepatoblastoma cell lines that can be induced to express each human PPAR and investigated the gene expression profiles of ...

However, the noisy nature of the gene expression and the scarcity of genomic data for many diseases are important limitations ... on how correlated are the gene expression patterns after treatment. Our classifier reaches high accuracy levels (78%), allowing ... Existing computational methods for drug repositioning either rely only on the gene expression response of cell lines after ... Analogously, let W D (g) be 1 minus the p-value of the gene g in the expression profile of drug D. The gene expression profile ...

Gene expression of CSE and 3MPST in the vessels has been evidenced by RT-PCR experiments, whereas the protein expression of all ... Na-GYY4137 produced a general 1.9 - 3.2-fold upregulation of splicing factor expression, whereas the mitochondria-targeted ... Gene expression of CSE and 3MPST in the vessels has been evidenced by RT-PCR experiments, whereas the protein expression of all ... Global transcriptional profiling following selective PKC inhibition identified significant changes in gene expression ...

Microarray Mavericks: Innovations and Applications in Gene Expression Profiling. Perspective: DOI: Huan Zhao *Full-text ... Alpha Fold Provides a Highly Accurate Prediction of Protein Structure. Perspective: J Appl Bioinforma Comput Biol. DOI: Yuan ... Profiling of Differential Expression of Genes in Mice Carrying Both Mutant Presenilin 1 and Amyloid Precursor Protein ... Solutions for Gene Expression Analysis and Genotyping. Perspective: J Appl Bioinforma Comput Biol. DOI: Roberto Mayor *Full- ...

Fold-change: 1.3. Z-score: 4.35. P-value: 5.98E-06 Target gene expression profiles of the patients in the disease section of ... Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section ... Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section ... Target gene expression profiles of the patients in the disease section of the tissue ...

The studies related to transcriptome profiling of gene expression in E-cigarette vapor and CS exposed human bronchial ... The highlighted spots (red color) with microRNA names are with greatest difference (at least two fold changes) in expression ... Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med (Berl). 2007;85(1): ... MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells. Sci Rep. 2017;7(1): ...

... were downregulated more than 10-fold in the 3D cells while Inhibitor Of DNA Binding 2, HLH Protein (ID2), Regulator Of Cell ... In this study, we examine gene expression changes through microarray analysis in spheroid versus monolayer ovarian cancer cells ... were increased more than 50-fold. Interestingly, stress responses and epigenetic processes were significantly affected by 3D ... Paullin, Trillitye, "Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models" (2016). USF Tampa ...

New Insights into the Gene Expression Profile of Heart Failure. Single-Nucleus Profiling of Human Dilated and Hypertrophic ... Partial Freezing of Rat Livers Extends Preservation Time by 5-Fold. Tessier SN, de Vries RJ, Pendexter CA, Cronin SEJ, Ozer S [ ... New Insights into the Gene Expression Profile of Heart Failure. Single-Nucleus Profiling of Human Dilated and Hypertrophic ... Our findings provide new insights into the gene expression profile of HF as well as new potential therapeutic targets for HF. ...