RCSB PDB - 4D4Y: Focal Adhesion Kinase catalytic domain
Upon cell adhesion to the extracellular matrix, FAK is being translocated toward focal adhesion sites and activated. ... Allosteric Regulation of Focal Adhesion Kinase by Pip2 and ATP.. Zhou, J., Bronowska, A., Le Coq, J., Lietha, D., Grater, F.. ( ... Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that regulates cell signaling, proliferation, migration, and ... Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that regulates cell signaling, proliferation, migration, and ...
RCSB PDB - 3GM1: Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif...
Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides ... Focal adhesion targeting (FAT) domains target the non-receptor tyrosine kinases FAK and Pyk2 to cellular focal adhesion areas, ... Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2. Lulo, J., Yuzawa, S., Schlessinger, J.. ( ... Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides. * ...
RCSB PDB - 4K9Y: FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p...
FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3 ... FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3 ... Fragment-based discovery of focal adhesion kinase inhibitors.. Gradler, U., Bomke, J., Musil, D., Dresing, V., Lehmann, M., ... Chemically diverse fragment hits of focal adhesion kinase (FAK) were discovered by surface plasmon resonance (SPR) screening of ...
Annotations: 7W7X
focal adhesion assembly. *positive regulation of focal adhesion assembly. *positive regulation of cellular component biogenesis ...