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*  Caspase-independent Cell Killing by Fas-associated Protein with Death Domain
Fas-associated protein with death domain (FADD), to the death domain of the Fas cytoplasmic region. This binding causes ... FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell. 1995;81: ... A novel protein that interacts with the death domain of Fas/ APO1 contains a sequence motif related to the death domain. J Biol ... Fas-associated protein with death domain. FKBP. FK506 binding protein. HA. hemagglutinin. PARP. poly(ADP-ribose) polymerase. ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2133085/?lang=en-ca
*  anti-FADD antibody | Rabbit Fas Associating Death Domain Containing Protein (FADD) Polyclonal Antibody-NP 034305.1
Rabbit Fas Associating Death Domain Containing Protein (FADD) Polyclonal Antibody-NP_034305.1 (MBS2004183) product datasheet at ... UniProt Protein Name FAS-associated death domain protein UniProt Synonym Protein Names FAS-associating death domain-containing ... NCBI Protein Information FAS-associated death domain protein ... Protein Family Fas-associated death domain protein UniProt Gene ... Polyclonal Antibody to Fas Associating Death Domain Containing Protein (FADD). Product Gene Name anti-FADD antibody. [Similar ...
https://www.mybiosource.com/prods/Antibody/Polyclonal/Fas-Associating-Death-Domain-Containing-Protein-FADD/FADD/datasheet.php?products_id=2004183
*  Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1β via Caspase-8 in Dendritic Cells | The...
Fas-associated death domain protein. IAP. inhibitor of apoptosis protein. Nec-1. necrostatin-1. P2X7R. P2X7 receptor. PARP. ... Anti-caspase-1 (p10) rabbit polyclonal (sc-514), anti-actin goat polyclonal (sc-1615), anti-Fas-associated death domain protein ... cellular FLICE inhibitory protein. cIAP. cellular inhibitor of apoptosis protein. DC. dendritic cell. Dox. doxorubicin. FADD. ... 43) have described a direct interaction between the death effector domain of procaspase-8 and the pyrin doman of ASC that can ...
http://www.jimmunol.org/content/191/9/4789.long
*  Remarkably Robust Antiviral Immune Response despite Combined Deficiency in Caspase-8 and RIPK3 | The Journal of Immunology
death receptor. FADD. Fas-associated death domain protein. HET. Casp8+/−Ripk3−/−. IM. inflammatory monocyte. Mac. macrophage. ... mixed-lineage kinase domain-like. pDC. plasmacytoid DC. PM. patrolling monocyte. pre-cDC. precursor-like cDC. RHIM. RIP ... receptor-interacting protein kinase. RT. room temperature. SG. salivary gland. vIRA. viral inhibitor of RIP activation. WT. ... Casp8 and RIPK3 are natural targets of virus-encoded cell death suppressors that prevent infected cell apoptosis and ...
http://www.jimmunol.org/content/201/8/2244
*  Early Activation of Caspases during T Lymphocyte Stimulation Results in Selective Substrate Cleavage in Nonapoptotic Cells | JEM
Indeed, interference with pathways leading to caspase processing, as in Fas-associated death domain protein (FADD) knockout, ... Fas-associated death domain protein; HRP, horseradish peroxidase; IAP, inhibitor of apoptosis; PARP, poly(ADP-ribose) ... Death receptors such as TNFR and Fas can act as costimulatory molecules and enhance T cell proliferation (25)(26)(27). We have ... As a control for caspase-mediated cleavage, total proteins from 106 Jurkat cells cultured on uncoated or anti-Fas-coated plates ...
http://jem.rupress.org/content/190/12/1879
*  Host-pathogen interactions during apoptosis | SpringerLink
Fas-associated death domain protein. Wt. wild-type. This is a preview of subscription content, log in to check access. ... Hunt D W and McManus B M 1998 Interaction of viral proteins with host cell death machinery;Cell. Death. Differ. 8 653-659 ... Patel R C and Sen G C 1998 PACT, a protein activator of the interferon-induced protein kinase, PKR;EMBO J. 17 4379-4390CrossRef ... The induction of apoptosis upon infection results from a complex interaction of parasite proteins with cellular host proteins. ...
https://link.springer.com/article/10.1007/BF02970153
*  Search Results | jns
Neuronal expression of Fas-associated death domain protein and caspase-8 in the perinidal parenchyma of cerebral arteriovenous ... The expression and localization of phosphorylated Fas-associated death domain protein (pFADD) and cleaved caspase-8 was ...
https://thejns.org/search?f_0=author&q_0=Kenichiro+Kikuta
*  Maria Van Gurp
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD Tom Vanden Berghe ( ... Mitochondrial intermembrane proteins in cell death Maria Van Gurp (UGent) , Nele Festjens (UGent) , Geert van Loo (UGent) , ... Toxic proteins released from mitochondria in cell death Xavier Saelens (UGent) , Nele Festjens (UGent) , Lieselotte Vande Walle ... cell-death, zinc-finger protein, wd-40 repeat region, tumor-necrosis-factor, tbid, structural basis, signal-transduction ...
https://biblio.ugent.be/person/801001177393?sort=year.desc&sort=datecreated.desc&start=&limit=250
*  CASP10 - Caspase-10 precursor - Homo sapiens (Human) - CASP10 gene & protein
Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. ... FAS-associated death domain protein interleukin-1B-converting enzyme 2. Short name: ... present in a protein.,p>,a href='/help/family_and_domains_section' target='_top'>More...,/a>,/p>Family & Domainsi. Domains and ... PROSITE; a protein domain and family database. More...PROSITEi. View protein in PROSITE. PS01122 CASPASE_CYS, 1 hit. PS01121 ...
https://www.uniprot.org/uniprot/Q92851
*  Frontiers | Interplay between Inflammation and Cellular Stress Triggered by Flaviviridae Viruses | Microbiology
Virus RNA molecules are sensed by Toll-like receptors (TLRs), RIG-I-like receptors (RIG-I and MDA5) and RNA-dependent protein ... Virus RNA molecules are sensed by Toll-like receptors (TLRs), RIG-I-like receptors (RIG-I and MDA5) and RNA-dependent protein ... Simultaneously, the synthesis of virus RNA and proteins are distinguished in different compartments such as mitochondria, ER ... Simultaneously, the synthesis of virus RNA and proteins are distinguished in different compartments such as mitochondria, ER ...
https://www.frontiersin.org/articles/10.3389/fmicb.2016.01233/full
*  Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1...
Moreover, extensive BCR ligation induces death of mature B cells from C57BL/6-lpr/lpr mice as efficiently as those from C57BL/6 ... or an inhibitor of the adapter protein FADD/MORT1 blocks Fas-mediated apoptosis but has no effect on BCR ligation-induced ... In contrast, expression of Bcl-2 blocks BCR-mediated but not Fas-induced apoptosis in WEHI-231 cells. These results indicate ... and that BCR-mediated apoptosis of WEHI-231 cells does not require Fas or related molecules such as DR3, DR4 and DR5, as all of ...
https://www.semanticscholar.org/paper/Rapid-B-cell-apoptosis-induced-by-antigen-receptor-Yoshida-Higuchi/d760f3014fc0ae0a787466edd7d948b34d80b353
*  Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel | Springer for Research & Development
Protein CYR61 (9%,15%), Kallikrein-14 (9%,15%), FAS-associated death domain protein (7%,13%), Methionine aminopeptidase 2 (7%, ... Secretory carrier associated membrane protein 3, or FAS-associated death domain protein. Granzyme H is part of a group of ... Secretory carrier-associated membrane protein 3 (39%), FAS-associated death domain protein (41%), and Pancreatic prohormone (79 ... Secretory carrier-associated membrane protein 3 (39%), FAS-associated death domain protein (41%), and Pancreatic prohormone (79 ...
https://rd.springer.com/article/10.1186%2Fs13104-019-4237-9
*  Erin Connor : USDA ARS
Cloning and sequencing of the bovine fas-associated death domain protein (fadd) cdna. Germplasm Release. Accession Number ... CLONING AND SEQUENCING OF THE BOVINE FAS-ASSOCIATED DEATH DOMAIN PROTEIN (FADD) CDNA - ... CHARACTERIZATION OF BOVINE FAS-ASSOCIATED DEATH DOMAIN GENE. - Szperka, M.E., Connor, E.E., Paape, M.J., Williams, J.L., ... Characterization of bovine FAS-associated death domain gene. Animal Genetics. 36(1):63-66. ...
https://www.ars.usda.gov/people-locations/person?person-id=1099
*  Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells | Molecular...
... or the linker protein Fas-associated death domain protein expression suppressed the toxicity enhancing activity of sildenafil ( ... Knock down of CD95 or Fas-associated death domain protein suppressed drug combination toxicity. Combination toxicity was also ... or siRNA molecules to knock down expression of CD95 or Fas-associated death domain protein (FADD) (siCD95, siFADD). Thirty-six ... The small molecule inhibitor of RIP-1, necrostatin, blocks the death process known as "necroptosis," a nonapoptotic cell death ...
http://molpharm.aspetjournals.org/content/85/3/408?ijkey=f820bfe82a0e305ef17220f8eba6f3bfbff397ae&keytype2=tf_ipsecsha
*  Ghent University Academic Bibliography
1-dependent repression of fas-associated death domain protein (Fadd) Pieter Hindryckx (UGent) , Martine De Vos (UGent) , Peggy ... Tumor necrosis factor α-induced proteins: natural brakes on inflammation Peggy Jacques (UGent) and Dirk Elewaut (UGent) ... Synovial fluid derived iNKT cells in chronic arthritides show an increased PROGRAMMED DEATH-1 expression and anergic phenotype ...
https://biblio.ugent.be/publication?limit=100&q=author+exact+801000966825&q=author+exact+001996246963
*  KEGG PATHWAY: ko05142
FAS-associated death domain protein. K04398 caspase 8 [EC:3.4.22.61]. K04724 CASP8 and FADD-like apoptosis regulator. ... mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]. K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal ... serine/threonine-protein phosphatase 2A regulatory subunit A. K04354 serine/threonine-protein phosphatase 2A regulatory subunit ... A T. cruzi-secreted protein immunologically related to the complement component C9: evidence for membrane pore-forming activity ...
https://www.kegg.jp/dbget-bin/www_bget?ko05142
*  ABCA1 - Wikipedia
"Molecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein". J. ... The ABCA1 c-terminus contains a PDZ domain, responsible for mediating protein-protein interactions, as well as a VFVNFA motif ... Since this protein is needed throughout the body it is expressed ubiquitously as a 220-kDa protein. It is present in higher ... also known as the cholesterol efflux regulatory protein (CERP) is a protein which in humans is encoded by the ABCA1 gene. This ...
https://en.wikipedia.org/wiki/ABCA1
*  MYD88 - Wikipedia
Bannerman DD, Tupper JC, Kelly JD, Winn RK, Harlan JM (Feb 2002). "The Fas-associated death domain protein suppresses ... "Ultrastructural distribution of the death-domain-containing MyD88 protein in HeLa cells". Experimental Cell Research. 243 (1): ... In that species it is a universal adapter protein as it is used by almost all TLRs (except TLR 3) to activate the transcription ... Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene. Model organisms ...
https://en.wikipedia.org/wiki/MYD88
*  Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector...
Death domain-containing protein that similar to receptor interacting protein (RIP) of TNF-R pathway ... two ankyrin-repeat domain containing proteins, a RING-finger protein and two proteins related to the ubiquitin-mediated protein ... Fas-associated death domain protein. FQ92HJ001A68SH (0.031). Dredd caspase. A caspase involved in apoptosis ... Except four ribosomal proteins of D. melanogaster (ribosomal protein L41, mitochondrial ribosomal protein S5, S31 and L51), the ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-11-303
*  KCS Publications
Full-length Fas-associated Death Domain Protein Interacts with Short Form of Cellular FLICE Inhibitory Protein Mi Suk Jeong, Se ...
http://journal.kcsnet.or.kr/main/j_search/j_archives_sub.htm?qpage=j_search&spage=b_bkcs&dpage=ar&year=2006&vol=27&no=1
*  Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway. - Semantic Scholar
The specificity of CrmA indicates that the Sindbis virus-induced death pathway is similar to that induced by Fas or tumor ... These inhibitors appear to protect cells by inhibiting the cellular death pathway rather than impairing virus replication or by ... a family of death-inducing proteases, resulting in cleavage of several cellular substrates. To study the role of caspases in ... inhibited Sindbis virus-induced cell death, suggesting that cellular caspases facilitate apoptosis induced by Sindbis virus. ...
https://www.semanticscholar.org/paper/Sindbis-virus-induces-apoptosis-through-a-pathway.-Nava-Ros%C3%A9n/c2eb607b659f44b25893e5f957476e35fa3524ad
*  JCI - T cell apoptosis and reactive oxygen species
Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE- ... The Fas- and TNF-α-independent pathway for T cell death has been referred to as passive cell death or death by neglect, ... domains 1-4. Class 2 proteins are proapoptotic and Bax-like and contain BH domains 1-3. Class 3 proteins are included in a ... ACAD and the role of Bcl-2-related proteins. While Fas signaling contributes to the death of some activated T cells, it ...
https://www.jci.org/articles/view/18007
*  Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells | Breast Cancer Research | Full Text
The status of AMP-activated protein kinase (AMPK) and PEA15 signaling was investigated by immunoblotting. Pharmacological ... and immunoprecipitated with anti-Fas-associated death domain protein (FADD) antibody. The immunoprecipates were resolved by SDS ... Signaling by the death-receptor proteins, such as Fas and TNF-R1, leads to the formation of the death-induced silencing complex ... Frisch SM: Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis. Curr Biol. 1999, 9: ...
https://0-breast--cancer--research-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s13058-014-0420-z
*  Probiotic bacteria prevent Salmonella - induced suppression of lymphoproliferation in mice by an immunomodulatory mechanism |...
Probiotic bacteria increased expression of mRNA for clusters of differentiation antigen 2 (Cd2), protein tyrosine phosphatase ... and fas-associated death domain protein (Fadd) mRNA expression, which are involved in initial steps of the apoptosis activation ... We observed that probiotic bacteria were associated with suppression of caspase recruitment domain protein 10 (Card10), tumor ... g and the protein content of the supernatant was determined by the bicinchoninic acid protein assay (Pierce Chemical Co.) to ...
https://0-bmcmicrobiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12866-017-0990-x
*  Composition of the CD95 DISC in freshly isolated and cu | Open-i
We found that GC B cells ex vivo display a preformed inactive DISC containing Fas-associated death domain-containing protein ( ... We found that GC B cells ex vivo display a preformed inactive DISC containing Fas-associated death domain-containing protein ( ... We found that GC B cells ex vivo display a preformed inactive DISC containing Fas-associated death domain-containing protein ( ... We found that GC B cells ex vivo display a preformed inactive DISC containing Fas-associated death domain-containing protein ( ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2195905_JEM001318.f5&req=4