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*  Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa |...
MAP (mitogen-activated protein) kinases are a family of serine/threonine kinases that have a pivotal role in signal ... Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa. ... Here we report the cloning and characterization of a mouse homologue of extracellular-signal-regulated protein kinase (ERK)3. ... Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa ...
http://www.biochemj.org/content/346/1/169
*  Src Family Kinase Activity Is Required for Kit-mediated Mitogen-activated Protein (MAP) Kinase Activation, However Loss of...
Marshall C. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase ... MAP, mitogen-activated protein; ERK, extracellular signalregulated kinase; MEK, MAP/ERK kinase; RTK, receptor tyrosine kinase; ... but sensitivity to the MAP/extracellular signal-regulated kinase kinase inhibitor could be partially restored by expression of ... MAP) kinase, but it also inhibited Kit activation. However, MAP kinase activation was more sensitive than Kit activation to the ...
http://cgd.aacrjournals.org/cgi/content/full/11/6/305
*  CorpusUL: The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in...
... a selective inhibitor of the extracellular signal-regulated protein kinase (ERK) pathway. Moreover, downregulation of Hsp27 by ... Our results also show that the expression of the dual leucine zipper-bearing kinase (DLK), an upstream activator of the MAP ... Thus, these observations suggest that the DLK-ERK signaling pathway may act as a regulator of the interaction that occurs ... kinase pathways, is sufficient by itself to induce Hsp27 phosphorylation, cell periphery localization, and redistribution to ...
https://corpus.ulaval.ca/jspui/handle/20.500.11794/16749
*  Patent US6015892 - Oligonucleotide modulation of protein kinase C - Google Patents
Compositions and methods are provided for the treatment, detection and diagnosis of diseases associated with protein kinase C ... New nucleic acid sequences are provided which encode 3' untranslated regions of human protein kinase C alpha polynucleotide ... Methods of treating conditions amenable to therapeutic intervention by modulating protein kinase C expression with an ... Compositions and methods are provided for the treatment and diagnosis of diseases associated with protein kinase C. ...
http://www.google.com.au/patents/US6015892
*  Mitogen Activated Protein Kinase 1 (MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein...
MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein Tyrosine Kinase ERK2 or EC 2.7.11.24) - ... Global Markets Direct's, 'Mitogen Activated Protein Kinase 1 (MAP... ... 46 Pages Report] Check for Discount on Mitogen Activated Protein Kinase 1 ( ... Mitogen Activated Protein Kinase 1 (MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein ...
http://www.reportsnreports.com/reports/648583-mitogen-activated-protein-kinase-1-map-kinase-1-or-mapk-1-or-extracellular-signal-regulated-kinase-2-or-erk-2-or-protein-tyrosine-kinase-erk2-or-ec-271124-pipeline-review-h1-2016.html
*  Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that...
Extracellular Signal-Regulated MAP Kinases/genetics*. *Extracellular Signal-Regulated MAP Kinases/metabolism ... The downstream targets of the pathway are members of the extracellular regulated kinases (Erk1/2) family, suggesting that this ... The receptor-tyrosine kinase (RTK)/Ras/Raf pathway is an essential cascade for mediating growth factor signaling. It is ... Autophosphorylation of purified Erk2(R65S), Erk2(T188A), and Erk2(T188D) was tested by incubating the proteins in a kinase ...
https://www.ncbi.nlm.nih.gov/pubmed/26658610
*  Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals.
EC 2.7.11.13/Protein Kinase C; EC 2.7.11.13/Protein Kinase C-alpha; EC 2.7.11.24/Extracellular Signal-Regulated MAP Kinases; EC ... Extracellular Signal-Regulated MAP Kinases / metabolism. Humans. Phosphatidylinositol 3-Kinases / metabolism. Pressure / ... Protein-Tyrosine Kinases / antagonists & inhibitors, metabolism*. Signal Transduction / physiology. Time Factors. p38 Mitogen- ... CONCLUSIONS: Extracellular pressure stimulates cell proliferation and activates several signals. However, the mitogenic effect ...
http://www.biomedsearch.com/nih/Extracellular-pressure-stimulates-colon-cancer/15548175.html
*  Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K...
Extracellular Signal-Regulated MAP Kinases / metabolism*. HSP90 Heat-Shock Proteins / metabolism*. Male. Mesenchymal Stromal ... Phosphatidylinositol 3-Kinases; EC 2.7.11.1/Proto-Oncogene Proteins c-akt; EC 2.7.11.24/Extracellular Signal-Regulated MAP ... Phosphatidylinositol 3-Kinases / metabolism*. Proto-Oncogene Proteins c-akt / metabolism*. Rats. Rats, Sprague-Dawley. ... of Hsp90 not only elevates Bcl-2/Bax and Bcl-xL/Bax expression and attenuates cleaved caspase-3 expression via down-regulating ...
http://www.biomedsearch.com/nih/Heat-shock-protein-90-protects/20669351.html
*  MEDLINE - Results of the search |page 1|
Extracellular Signal-Regulated MAP Kinases/genetics. Extracellular Signal-Regulated MAP Kinases/metabolism. Gene Expression. ... Extracellular Signal-Regulated MAP Kinases); EC 3.1.3.48 (PTPN11 protein, human); EC 3.1.3.48 (Protein Tyrosine Phosphatase, ... This association once again raises the important question of the role of the Ras-MAPK signalling pathway in the development of ... SHP2 plays a key role in RAS/MAPK pathway signaling which controls several developmental cell processes and oncogenesis. An ...
http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&base=MEDLINE&lang=i&nextAction=lnk&isisFrom=1&count=10&exprSearch=noonan%20and%20syndrome
*  Photomicrographs showing changes in CD11/b-IR in the sp | Open-i
Extracellular Signal-Regulated MAP Kinases/metabolism*. *Inflammation/drug therapy*/enzymology*/pathology. *Neurons/drug ... EP also attenuated the phosphorylation of extracellular signal-regulated kinase (ERK) in the neurons of L4-L5 spinal dorsal ... EP also attenuated the phosphorylation of extracellular signal-regulated kinase (ERK) in the neurons of L4-L5 spinal dorsal ... Interestingly, the i.t. administration of PD98059, an ERK upstream kinase (MEK) inhibitor, completely blocked the formalin- ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3472237_1744-8069-8-40-5&req=4
*  Epidermal growth factor (EGF) influences activity of Ja | Open-i
Extracellular Signal-Regulated MAP Kinases/metabolism. *Flavonoids/pharmacology. *Humans. *Immunohistochemistry. *Intracellular ... and extracellular signal-regulated kinase (ERK) pathway inhibitor. A cohort of 424 human breast tumors was also assessed by ... and extracellular signal-regulated kinase (ERK) pathway inhibitor. A cohort of 424 human breast tumors was also assessed by ... these results indicate not only that EGFR signaling affects Jab1 translocation but that it may regulate targets downstream of ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2481501_bcr2105-3&req=4
*  Gentaur Molecular :EIAab \ ELISA Erk1,ERK-1,ERT2,Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP...
Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1,MAPK 3,Mapk3,Microtubule-associated ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1, ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1, ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1, ...
http://www.antibody-antibodies.com/product3085593-search-ELISA_Erk1,ERK_1,ERT2,Extracellular_signal_regulated_kinase_1,Insulin_stimulated_MAP2_kinase,MAP_kinase_1,MAP_kinase_3,MAP_kinase_isoform_p44,MAPK_1,MAPK_3,Mapk3,Microtubule_associated_protein_2_kinas.html
*  Mitogen-Activated Protein Kinase 8 Summary Report | CureHunter
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the ... Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases) 6. STAT5 Transcription Factor ... kinase-1-dependent MEK-extracellular signal-regulated protein kinase 1/2 (ERK1/2) and c-Jun N-terminal kinase 1/2 (JNK1/2) ... signal transducer and activator of transcription 5, extracellular signal-regulated kinases, MMP-9 and pan-janus kinase/stress- ...
http://www.curehunter.com/public/keywordSummaryD048055.do
*  Gentaur Molecular :EIAab \ CLIA Erk1,ERK-1,ERT2,Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP...
MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1,MAPK 3,Mapk3,Microtubule-associated protein 2 kinase \ U1357r for more ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase, ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1, ... Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP kinase isoform p44,MAPK 1, ...
http://www.antibody-antibodies.com/product3080344-search-CLIA_Erk1,ERK_1,ERT2,Extracellular_signal_regulated_kinase_1,Insulin_stimulated_MAP2_kinase,MAP_kinase_1,MAP_kinase_3,MAP_kinase_isoform_p44,MAPK_1,MAPK_3,Mapk3,Microtubule_associated_protein_2_kinase.html
*  Gene: [22q112/PRKM1] protein kinase, mitogen-activated 1; MAP kinase 1 (p40, p41); extracellular signal-regulated kinase 2 (p42...
Gene: [22q112/PRKM1] protein kinase, mitogen-activated 1; MAP kinase 1 (p40, p41); extracellular signal-regulated kinase 2 (p42 ... They are part of complex protein kinase cascades. MAPKs are activated by dual-specificity MAPK kinases (MAPKKs; see GEM:05^/ ... 1] Mitogen-activated protein kinases (PRKMs, or MAPKs) are serine-threonine protein kinases that are activated in response to a ...
http://humbio.ru/humbio/hugen/22q112_prkm1.htm
*  becker nevus 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Extracellular Signal-Regulated MAP Kinases ... Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor ... Protein-Serine-Threonine Kinases / genetics. Tumor Suppressor Proteins / genetics. *Genetic Alliance. consumer health - Ataxia. ... Chemical-registry-number] 0 / Intracellular Signaling Peptides and Proteins; 0 / RNA, Messenger; 0 / Retinoblastoma Protein; 0 ...
http://www.bmlsearch.com/?kwr=becker+nevus+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  acute promyelocytic leukemia childhood 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Extracellular Signal-Regulated MAP Kinases; EC 3.4.25.1 / Proteasome Endopeptidase Complex ... fms-Like Tyrosine Kinase 3 / blood. fms-Like Tyrosine Kinase 3 / genetics ... Cyclin-Dependent Kinase Inhibitor p27; EC 2.4.2.30 / Poly(ADP-ribose) Polymerases; EC 2.7.11.22 / CDC2 Protein Kinase; EC 2.7. ... 11.22 / Cyclin-Dependent Kinases; EC 3.4.22.- / CASP3 protein, human; EC 3.4.22.- / Caspase 3; EC 3.4.22.- / Caspases; ...
http://www.bmlsearch.com/?kwr=acute+promyelocytic+leukemia+childhood+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Bellido, T.<...
Extracellular Signal-Regulated MAP Kinases Argentina Research CYTOKINE SIGNAL TRANSDUCTION IN OSTEOBLASTIC CELLS. Bellido, T. ... MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production. Delgado ... IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production. Li ...
https://indiana.pure.elsevier.com/en/persons/teresita-bellido
*  "The novel organic arsenical darinaparsin induces MAPK-mediated and SHP" by Dashnamoorthy Ravi, Savita Bhalla et al.
Extracellular Signal-Regulated MAP Kinases; Glutathione; Hodgkin Disease; Humans; Intracellular Space; Lymphoma, T-Cell; Mice; ... Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Signal Transduction; Tumor Burden; ...
https://escholarship.umassmed.edu/ssp/209/
*  anti-Chemokine (C-C Motif) Ligand 13 Primary Antibodies
... secreted CCL13 enhances fibroblast-like synoviocyte proliferation by activating the extracellular signal-regulated MAP kinases ... CCL13 and HSPC159 mRNA expressions in PBMC are up-regulated specifically in MCNS patients during the nephrosis phase. ... anti-Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) Antikörper ...
https://www.antikoerper-online.de/regulation-of-systemic-arterial-blood-pressure-by-hormones-pathway-45/ccl13-antibody-17492/
*  Insulin/IGF-I regulation of necdin and brown adipocyte differentiation via CREB- and FoxO1-associated pathways - Danish...
Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Insulin; Insulin Receptor Substrate Proteins; ... By contrast, forkhead box protein (Fox)O1, which is regulated by the phosphoinositide 3 kinase-Akt pathway, increased necdin ... This signaling did not include an elevation of intracellular calcium. A constitutively active form of CREB expressed in IRS-1 ... Signal Transduction Main Research Area: Science/technology Publication Status: Published Review type: Peer Review Submission ...
https://www.forskningsdatabasen.dk/en/catalog/185433938
*  Ted Acott - Publications - Oregon Health & Science University
Extracellular Signal-Regulated MAP Kinases Mitogen-Activated Protein Kinases Matrix Metalloproteinases Trabecular Meshwork ... p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells. Kelley, M., Rose, A., Song, K., Lystrup, B., ... Mapping molecular differences and extracellular matrix gene expression in segmental outflow pathways of the human ocular ... Involvement of the Erk-MAP kinase pathway in TNFα regulation of trabecular matrix metalloproteinases and TIMPs. Alexander, J. P ...
https://ohsu.pure.elsevier.com/en/persons/ted-acott/publications/
*  Extracellular signal-regulated kinases - Wikipedia
The Extracellular Signal-Regulated Kinases MAP Kinase Resource . Extracellular Signal-Regulated MAP Kinases at the US National ... "MAP kinase-kinase", thus qualifying as a "MAP kinase kinase kinase". The MAP kinase-kinase, which activates ERK, was named " ... extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular ... Mitogen-activated protein kinase 1 (MAPK1) is also known as "extracellular signal-regulated kinase 2" (ERK2). Two similar (85% ...
https://en.wikipedia.org/wiki/Extracellular_signal%E2%80%93regulated_kinases
*  Research programme: fixed dose combination therapies - Celator - AdisInsight
Extracellular signal-regulated MAP kinase inhibitors; Histone acetyltransferase inhibitors; Histone deacetylase inhibitors; ... Mitogen-activated protein kinase kinase inhibitors; MTOR protein inhibitors; Proto oncogene protein c-akt inhibitors; Raf ... Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Apoptosis modulators; DNA cross linking agents; DNA synthesis ... kinase inhibitors; Ras protein inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory body to encourage ...
https://adisinsight.springer.com/drugs/800023960?error=cookies_not_supported&code=b0aeb559-e01c-446c-8bd4-b086ef7ab81c