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*  EXOSC4 Gene - GeneCards | EXOS4 Protein | EXOS4 Antibody
GO annotations related to this gene include 3-5-exoribonuclease activity and exoribonuclease activity. An important paralog of ... Dis3-like 1: a novel exoribonuclease associated with the human exosome. (PMID: 20531389) Staals RH … Pruijn GJ (The EMBO ... Non-catalytic component of the RNA exosome complex which has 3-,5 exoribonuclease activity and participates in a multitude of ... Non-catalytic component of the RNA exosome complex which has 3-,5 exoribonuclease activity and participates in a multitude of ...
http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=54512
*  Characterization of RNA exosome in Insect Cells : Role in mRNA Surveillance
4. The Intranuclear Localization of the Exoribonuclease Rrp6 in Insect Cells. Open this publication in new window or tab ,,The ... Intranuclear Localization of the Exoribonuclease Rrp6 in Insect Cells. Hessle, Viktoria. Stockholm University, Faculty of ...
http://su.diva-portal.org/smash/record.jsf?pid=diva2:386816
*  CBI Career | Elisabeth Abshire
Nocturnin (NOCT) is broadly expressed enzyme with exoribonuclease activity in in vitro assays and a repressive function against ...
http://cbicareer.org/?page_id=6561
*  "Additional functional roles of {\it Escherichia coli\/} polynucleotide" by Zhihua Zhou
... double mutant strain revealed an important functional aspect of these two Pi-dependent exoribonucleases in E. coli, i.e., they ... exoribonuclease activity. However, there are many unexplained observations related to the physiological role of this enzyme. ... exoribonuclease activity. However, there are many unexplained observations related to the physiological role of this enzyme. ... double mutant strain revealed an important functional aspect of these two Pi-dependent exoribonucleases in E. coli, i.e., they ...
http://opencommons.uconn.edu/dissertations/AAI9806196/
*  3'-5' exoribonuclease Rv2179c-like domain (IPR033390) | InterPro | EMBL-EBI
3'-5' exoribonuclease Rv2179c-like domain (IPR033390). Short name: Rv2179c-like Overlapping homologous superfamilies * ... This entry represents a domain found in a group of divergent 3' exoribonucleases. The proteins constitute a typical RNase fold ... Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution.. J. ...
https://www.ebi.ac.uk/interpro/entry/IPR033390
*  Eri1 - 3'-5' exoribonuclease 1 - Rattus norvegicus (Rat) - Eri1 gene & protein
3'-5' exoribonuclease 1Add BLAST. 345. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view. ... sp,Q5FVR4,ERI1_RAT 3'-5' exoribonuclease 1 OS=Rattus norvegicus OX=10116 GN=Eri1 PE=2 SV=1 ...
http://www.uniprot.org/uniprot/Q5FVR4
*  Exoribonuclease - Wikipedia
Exoribonucleases exist in all kingdoms of life, the bacteria, archaea, and eukaryotes. Exoribonucleases are involved in the ... Hydrolytic exoribonucleases are classified under EC number 3.1 and phosphorolytic exoribonucleases under EC number 2.7.7. As ... exoribonucleases. Exoribonucleases can use either water to cleave the nucleotide-nucleotide bond (which is called hydrolytic ... Exoribonucleases can be single proteins (such as RNase D or RNase PH) but also can be complexes of multiple proteins, such as ...
https://en.wikipedia.org/wiki/Exoribonuclease
*  Exoribonuclease II - Wikipedia
... exoribonuclease (misleading), 5'-exoribonuclease) is an enzyme. This enzyme catalyses the following chemical reaction ... Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, ... Exoribonuclease II at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal ... 5'-3' exoribonuclease 2 Nossal, N.G.; Singer, M. (1968). "The processive degradation of individual polyribonucleotide chains. I ...
https://en.wikipedia.org/wiki/Exoribonuclease_II
*  Activation of 5′-3′ exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast | PNAS
5′-3′ Exoribonuclease Activity Is Required for Growth on Glycerol.. Dcs1 has been shown to stimulate Xrn1 activity (4), and a ... In vitro assays of 5′ to 3′-exoribonuclease activity by RT-FeDEX (23). The fluorophore (FAM) linked to RNA is hybridized to a ... We analyzed the role of Dcs1 in the control of exoribonuclease activity in vitro and propose that Dcs1 is a specific cofactor ... 1B), showing that this defect is related to the enzyme's exoribonuclease activity. We were also able to rescue this growth ...
http://www.pnas.org/content/109/21/8264
*  Reactome | mRNA decay by 5' to 3' exoribonuclease
Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge.
http://www.reactome.org/content/detail/R-SSC-430039
*  XRN1 - 5'-3' exoribonuclease 1 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - XRN1 gene & protein
IPR027073 5_3_exoribonuclease. IPR016494 5_3_exoribonuclease_1. IPR004859 Put_53exo. IPR014722 Rib_L2_dom2. ... IPR027073 5_3_exoribonuclease. IPR016494 5_3_exoribonuclease_1. IPR004859 Put_53exo. IPR014722 Rib_L2_dom2. ... 5'-3' exoribonuclease 1Add BLAST. 1528. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view ... "Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae.". Page A.M., Davis K., Molineux C., Kolodner R.D., ...
https://www.uniprot.org/uniprot/P22147&format=html
*  ETHYLENE-INSENSITIVE5 encodes a 5′→3′ exoribonuclease required for regulation of the EIN3-targeting F-box proteins EBF1/2 | PNAS
EIN5 Identified as the 5′→3′ Exoribonuclease XRN4.. We cloned the EIN5 gene using a map-based approach (Fig. 2 A). ein5-1 and ... 4 E and F). Taken together, these results demonstrate that the XRN4/EIN5 exoribonuclease regulates EBF1 and EBF2 at the ... 1). Upon cloning EIN5 we were surprised to find that it codes for the previously described 5′→3′ exoribonuclease XRN4. XRN4/ ... EIN5, a 5′→3′ exoribonuclease, is involved in facilitating the turnover of EBF1/EBF2 mRNA through a yet unknown mechanism. ...
https://www.pnas.org/content/103/36/13286
*  negative regulation of exoribonuclease activity - Semantic Scholar
... rate or extent of exoribonuclease activity. [GOC:TermGenie, PMID:22570495] ... negative regulation of exoribonuclease activity. Known as: down regulation of exoribonuclease activity, down-regulation of ... An exoribonuclease from calf thymus which specifically cleaves poly(A) in the single- or in the double-stranded form has been… ... The exoribonuclease Xrn1 is widely recognised as a key component in the 5'-3' RNA degradation pathway. This enzyme is highly… ( ...
https://www.semanticscholar.org/topic/negative-regulation-of-exoribonuclease-activity/7728632
*  Plus it
The Exoribonuclease XRN4 Is a Component of the Ethylene Response Pathway in Arabidopsis. Thomas Potuschak, Amérin Vansiri, Brad ... ein5 and ein7 Are Mutants in the Exoribonuclease XRN4.. (A) Phenotypes of 4-d-old etiolated seedlings of the indicated ... EIN5 Is Allelic to the Exoribonuclease XRN4. A recent microarray analysis by Souret et al. (2004) identified the EBF1 mRNA ( ... Newbury, S., and Woollard, A. (2004). The 5′-3′ exoribonuclease xrn-1 is essential for ventral epithelial enclosure during C. ...
http://www.plantcell.org/content/18/11/3047
*  Frontiers | The exoribonuclease Polynucleotide Phosphorylase influences the virulence and stress responses of yersiniae and...
... cold growth is dependent on the presence of an exoribonuclease, polynucleotide phosphorylase (PNPase). PNPase has also been ... cold growth is dependent on the presence of an exoribonuclease, polynucleotide phosphorylase (PNPase). PNPase has also been ... Deutscher, M. P., and Li, Z. (2001). Exoribonucleases and their multiple roles in RNA metabolism. Prog. Nucleic Acid Res. Mol. ... Originally identified in E. coli, PNPase, encoded by the pnp gene, is an ~80 kDa homo-trimeric exoribonuclease that poorly ...
https://www.frontiersin.org/articles/10.3389/fcimb.2013.00081/full
*  XRN2 recombinant protein | 5'-3' exoribonuclease 2 (XRN2) Recombinant Protein-NP 001304889.1
... exoribonuclease 2 (XRN2) Recombinant Protein-NP_001304889.1 (MBS1319027) product datasheet at MyBioSource, Recombinant Proteins ... Possesses 5'->3' exoribonuclease activity (). May promote the termination of transcription by RNA polymerase II. During ...
https://www.mybiosource.com/xrn2-recombinant-protein/5-3-exoribonuclease-2-xrn2/1319027
*  CRYSTAL STRUCTURES OF CRISPR-ASSOCIATED CSX3 REVEAL A MANGANESE-DEPENDENT DEADENYLATION EXORIBONUCLEASE | ScholarBank@NUS
YAN XINFU (2015-07-31). CRYSTAL STRUCTURES OF CRISPR-ASSOCIATED CSX3 REVEAL A MANGANESE-DEPENDENT DEADENYLATION EXORIBONUCLEASE ... CRYSTAL STRUCTURES OF CRISPR-ASSOCIATED CSX3 REVEAL A MANGANESE-DEPENDENT DEADENYLATION EXORIBONUCLEASE. ...
http://scholarbank.nus.edu.sg/handle/10635/122005
*  Glucose 6-phosphatase - Wikipedia
Although a clear consensus has not been reached, a large number of scientists adhere to a substrate-transport model to account for the catalytic properties of glucose-6-phosphatase. In this model, glucose-6-phosphatase has a low degree of selectivity. The transfer of the glucose 6-phosphate is carried out by a transporter protein (T1) and the endoplasmic reticulum (ER) contains structures allowing the exit of the phosphate group (T2) and glucose (T3).[6] Glucose-6-phosphatase consists of 357 amino acids, and is anchored to the endoplasmic reticulum (ER) by nine transmembrane helicies. Its N-terminal and active site are found on the lumen side of the ER and its C-terminus projects into the cytoplasm. Due to its tight association to the ER, the exact structure of glucose-6-phosphatase remains unknown. However, sequence alignment has shown that glucose-6-phosphatase is structurally similar to the active site of the vanadium-containing chloroperoxidase found in Curvularia inaequalis.[7] Based on pH ...
https://en.wikipedia.org/wiki/Glucose_6-phosphatase
*  Deoxyribonuclease II - Wikipedia
Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA, yielding products with 3'-phosphates. As the name implies, it is more effective at acid pH.. There are several known DNases II, including:. ...
https://en.wikipedia.org/wiki/Deoxyribonuclease_II
*  Table of Contents - June 29, 2012, 336 (6089) | Science
Elastic Coupling Between RNA Degradation and Unwinding by an Exoribonuclease. By Gwangrog Lee, Matthew A. Bratkowski, Fang Ding ...
https://science.sciencemag.org/content/336/6089
*  Exosc7 exosome component 7 [Mus musculus (house mouse)] - Gene - NCBI
mRNA decay by 3' to 5' exoribonuclease, organism-specific biosystem (from REACTOME) mRNA decay by 3' to 5' exoribonuclease, ... RNase_PH; RNase PH-like 3'-5' exoribonucleases. * XM_006512207.3 → XP_006512270.1 exosome complex exonuclease RRP42 isoform X1 ...
https://www.ncbi.nlm.nih.gov/gene/?term=66446
*  Laboratories - IIMCB
Mitochondrial exoribonuclease complex mtEXO. RNA degradation pathways play crucial roles in processing of various types of RNA ... Crystal structure of Dss1 exoribonuclease from Candida glabrata reveals it is a unique member of the RNase II family with ... Crystal structure of Candida glabrata mtEXO complex shows the arrangement of the Suv3 helicase on top of Dss1 exoribonuclease ... composed of Dss1 3ʹ-to-5ʹ exoribonuclease and Suv3 helicase. ...
https://www.iimcb.gov.pl/en/research/laboratories/6-laboratory-of-protein-structure-nowotny-laboratory
*  A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. | CureHunter
Exoribonucleases (chemistry, genetics, metabolism) *Female. *Gene Expression. *Hearing Loss, Sensorineural (genetics, ...
http://www.curehunter.com/public/pubmed23084290.do