Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses | PNAS
Endocytic recycling of synaptic vesicles after exocytosis is critical for nervous system function. At synapses of cultured ... up by a defect in dynamin-dependent endocytosis and provide new insight into the coupling between endocytosis and exocytosis. ...
Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease | PNAS
α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein ...