Long non-coding RNA UASR1 promotes proliferation and migration of breast cancer cells through the AKT/mTOR pathway
Dissociation of the eukaryotic initiation factor-4E/4E-BP1 complex involves phosphorylation of 4E-BP1 by an mTOR-associated ... H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-beta-Catenin Signaling in Colorectal ... Eukaryotic regulatory RNAs: an answer to the genome complexity conundrum. Genes Dev. 2007;21:11-42 ... Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999;96:857-68 ...
Effects of Lithium and Valproic Acid on Gene Expression and Phenotypic Markers in an NT2 Neurosphere Model of Neural...
The house keeping genes Ubiquitin C (UBC), Eukaryotic initiation factor 4A2 (eIF4A2), 18S ribosomal RNA, Glyceraldehyde 3- ... 2008) Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 26 ... G1-S Growth factor regulation). GO analysis of the VPA deregulated genes (Table 2) revealed a significant (p,0.05) ...
Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing | Journal of...
Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII. Mol. Cell. Biol. ... Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII. Mol. Cell. Biol. ... A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A. Biochem. Biophys. Res. Commun. ... A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A. Biochem. Biophys. Res. Commun. ...
![Recombinant Anti-Collagen X antibody [EPR22920-211] (ab260040) | Abcam](data:image/png;base64,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)
Recombinant Anti-Collagen X antibody [EPR22920-211] (ab260040) | Abcam
真核翻译起始因子 2α 激酶 3（EIF2AK3）基因 | MCE
eukaryotic translation initiation factor 2-alpha kinase 3 isoform X3 XM_045368915.1. XP_045224850.1. eukaryotic translation ... initiation factor 2-alpha kinase 3 isoform X2 XM_005575342.2. XP_005575399.2. eukaryotic translation initiation factor 2-alpha ... Cytokines and Growth Factors. Immune Checkpoint Proteins. CAR-T related Proteins. CD Antigens. Fc Receptors. Receptor Proteins ... Cytokines and Growth Factors细胞因子和生长因子 ... eukaryotic translation initiation factor 2 alpha kinase 3 Gene ...
Simon Cook - Publications | Babraham Institute
... an increase in expression of the eukaryotic translation initiation factor eIF4E and increased cap-dependent mRNA translation. ... Nuclear factor-κB (NF-κB) is one of the most important transcription factors that controls inducible gene expression as cells ... The transcription factor hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tumour growth and progression, and HIF-1 is ... mTOR activity is regulated both by the availability of growth factors, such as insulin/IGF-1 (insulin-like growth factor 1), ...
Haemodynamic definitions and updated clinical classification of pulmonary hypertension | European Respiratory Society
... due to biallelic mutations in the eukaryotic translation initiation factor 2α kinase 4 (EIF2AK4) gene [52-54]. Occupational ... Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004; 350: 886-895. ... Prevalence and risk factors for pulmonary arterial hypertension in a large group of β-thalassemia patients using right heart ... Occupational exposure to organic solvents: a risk factor for pulmonary veno-occlusive disease. Eur Respir J 2015; 46: 1721-1731 ...
FOXC1 | Cancer Genetics Web
... eukaryotic initiation factor 4E (eIF4E) and B-cell lymphoma-2 (bcl-2) were determined with immunohistochemistry tests.. RESULTS ... transcription factor binding - transcription factor complex - transcription regulatory region DNA binding - ureteric bud ... Little is known about possible risk factors predictive for the frequent (ie, up to 16%) life-threatening or lethal toxicities ... This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead ...
EFTR for NASDAQ:EFTR by BADQOMOCAWGOWLD - TradingView
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism | eLife
... and activating transcription factor 6 (ATF6). PERK directly phosphorylates eukaryotic translation initiation factor 2 α (eIF2α ... 2016) Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and ... fibroblast growth factor (Fgf) 1 and 2, hepatocyte growth factor (Hgf), and stromal-derived factor 1 (Sdf1) which are known to ... 2008) Nuclear factor-kappa B signaling in skeletal muscle atrophy Journal of Molecular Medicine 86:1113-1126. ...
IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans | BMC Biology | Full Text
IMPACT inhibits the ISR pathway, thus limiting the activation of stress response factors that are beneficial during aging and ... Impt-1 knockdown exacerbated DR-induced longevity and required several DR-activated transcription factors to extend lifespan, ... Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits. ... Kubota H, Sakaki Y, Ito T. GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its ...
Checkpoint Kinase (Chk)
![Effect of the Insulin Mimetic L-783,281 on Intracellular [Ca2+] and Insulin Secretion From Pancreatic β-Cells | Diabetes |...](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAMAAAAoLQ9TAAAAYFBMVEWmHS////+lGy2wNkalGizz4uPDZ3H9+/uoITK9W2asLDvnxcfu1tivNkT89/fSj5Ts0dK2SFTLfYXcqa25UFvqys7htbj57/DZoaatLz68WWLv2drNgonkvcDUlZqzQU75AR6dAAAAiElEQVQYlY2O2Q7CIBBFuexlswsFUdv+/19KqTH45nmYZG7OZC4hf8IHSfudGuv8rxBw6xXqR4ipS4yZFRb9PYirWyzywD++TggyZlhzHXEZkDS5Q81XUFbkhyaTwNOfCX0B2W5bSgp7Degh0EjHiBx5FUTDRS6F2Ovrwhq1uWasnF1ooxWo8w0nEgV6VVbmdAAAAABJRU5ErkJggg==)
Effect of the Insulin Mimetic L-783,281 on Intracellular [Ca2+] and Insulin Secretion From Pancreatic β-Cells | Diabetes |...
... eukaryotic initiation factor-4E) (7). In addition, maximal insulin secretion corresponds with maximal production of ...
The AKT1 gene and its putative association with human ageing
... signalling pathway which controls the assembly of the eukaryotic translation initiation factor 4F (eIF4E) complex and this ... in response to insulin growth factor-1 and epidermal growth factor. Protein phosphatases act as negative regulators of AKT ... Survival factors can suppress apoptosis in a transcription-independent manner by activating AKT1 which then phosphorylates and ... pathway, in addition to responding to extracellular signals from growth factors and cytokines, is disregulated in many cancers ...
PEK subfamily | Enzymes | IUPHAR/BPS Guide to PHARMACOLOGY
CoP: Co-expressed Biological Processes
eukaryotic translation initiation factor-related. F:molecular_function unknown;P:biological_process unknown;C:cellular_ ... SLR/IAA14-dependent auxin induced lateral root initiation. 9.8. 99.1. GSM143306. High_Na_seg_pool_tsu_col_F2. GSE6203. Rus_etal ... Transcription factor, : Binding protein, : Enzyme protein, : Other protein. : VF over 0.50, : over 0.25, : below 0.25. Co- ... SLR/IAA14-dependent auxin induced lateral root initiation. 12.6. 99.3. GSM265422. Arabidopsis, root, longitudinal zone 3, ...
FGen products | Page 1 of 4 - Gentaur Molecular Products
Polyclonal Antibody Eukaryotic translation initiation factor 4E, family 3 AB Immunogen: peptide Host: Rabbit. 200ul. 391.36 €. ... Polyclonal Antibody Eukaryotic translation initiation factor 4E, family 3 AB Immunogen: peptide Host: Rabbit. 200ul. 391.36 €. ... Polyclonal Antibody Post GPI attachment to Protein Factor (N-epitoope) Immunogen: peptide Host: Rabbit. 200ul. 391.36 €. -. ... Polyclonal Antibody Post GPI attachment to Protein Factor (Mid-region) Immunogen: peptide Host: Rabbit. 200ul. 391.36 €. -. ...
Genomes encoding eukaryotic-like proteins | EffectiveDB
PF07541 Eukaryotic translation initiation factor 2 alpha subunit. Copy number in non-pathogens:. Mean=0.00 Stddev=0.00 ... Genomes significantly enriched in this eukaryotic-like domain (ELD; score ,= 4):. Genome. Class*. ELD score. Number of proteins ... EFFECTIVEELD 5.2: EUKARYOTIC-LIKE DOMAIN PREDICTION UPGRADED TO PFAM 31. 20.08.17 ... EffectiveELD 5.1: Eukaryotic-like domain prediction upgraded to Pfam 29. 24.06.16 ...
Products | Abnova
ExplorEnz: EC 1.14.99.29
EIF3F - MSGP
Arabidopsis thaliana protein interaction networks
EIF3C (EUKARYOTIC TRANSLATION INITIATION FACTOR 3C) TRANSLATION INITIATION FACTOR AT5G62600. Predicted. two hybrid. two hybrid ... EIF3A (EUKARYOTIC TRANSLATION INITIATION FACTOR 3A) TRANSLATION INITIATION FACTOR AT4G35310. Predicted. Affinity Capture-MS. ... EIF4G (EUKARYOTIC TRANSLATION INITIATION FACTOR 4G) TRANSLATION INITIATION FACTOR AT4G19006. Predicted. two hybrid. interaction ... EIF3B-2 (EUKARYOTIC TRANSLATION INITIATION FACTOR 3B-2) NUCLEIC ACID BINDING / PROTEIN BINDING / TRANSLATION INITIATION FACTOR ...
RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data.
Dual Inhibition of mTOR and Estrogen Receptor Signaling In vitro Induces Cell Death in Models of Breast Cancer | Clinical...
... and inhibiting the eukaryotic initiation factor 4E binding proteins (4E-BP1-3). The S6Ks have been implicated in the ... thereby allowing reconstitution of a translationally competent initiation factor complex (eIF-4F). The eIF-4F complex also ... ER is a member of a family of nuclear transcription factors exhibiting both ligand-dependent and ligand-independent ... Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance. Clin ...
DSpace
... by pre-treating the cells with a drug that pharmacologically inhibits the phosphorylation of eukaryotic initiation factor 2α( ... It is important to note that due to limitations and the retrospective nature of this study, only the co-contributing factors ... Aim: The aim of this retrospective study was to determine the implant failure rate and associated factors in the academic ... Secondary objective was to investigate the co-contributing factors for implant failure at the patient level. Method and ...
Jose L. Pena - Publications - Albert Einstein College of Medicine
DeCS
Eukaryotic Initiation Factor 2alpha Kinase Heme Controlled Inhibitor Heme Controlled Repressor Heme Controlled Translational ... Eukaryotic Initiation Factor 2alpha Kinase. Heme Controlled Inhibitor. Heme Controlled Repressor. Heme Controlled Translational ... The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the ... The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the ...
CIPSM - Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches
EF-P is present in all bacteria and orthologous to archaeal and eukaryotic initiation factor 5A, yet the biological function ... Bacterial, archaeal, and eukaryotic cells have hundreds to thousands of polyproline-containing proteins of diverse function, ... Here, we demonstrate that EF-P is an elongation factor that enhances translation of polyproline-containing proteins: In the ... Translation elongation factor P (EF-P) is critical for virulence in bacteria. ...
The combination of intravenous Reolysin and gemcitabine induces reovirus replication and endoplasmic reticular stress in a...
... recognizes viral particles and results in abrogation of protein synthesis by phosphorylation of eukaryotic initiation factor 2 ...