HBD fusions - Picard Lab home  HBD fusions - Picard Lab home
... factor transcription factor as DNA binding factor transcription factor transcription factor in fish transcription factor in ... Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from ... Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. USA 93, 10887-10890 (1996). Zhang, Y. et al. ... transcription factor transcription factor transcription factor transcription factor MT-MC1 v-Myb c-Myc MyoD ER e ER ER, GR ER, ...
more infohttp://spotidoc.com/doc/695589/hbd-fusions---picard-lab-home
ZFIN Publication: Blake et al., 2000  ZFIN Publication: Blake et al., 2000
DNA-Binding Proteins/metabolism. *Embryo, Nonmammalian/metabolism. *Erythroid-Specific DNA-Binding Factors ... Mammalian CBFB encodes a transcription factor (CBFbeta) that in combination with CBFalpha2 binds to specific DNA sequences and ... In biochemical analyses, cbfbeta binds to human CBFalpha2 and enhances its DNA binding. During zebrafish development, cbfb is ... We have isolated a zebrafish cbfb complementary DNA (cDNA) clone from a zebrafish kidney cDNA library. This cbfb is highly ...
more infohttp://zfin.org/ZDB-PUB-001221-16
GATA1 - Wikipedia  GATA1 - Wikipedia
"Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor". Nature. 338 ( ... DNA binding. • p53 binding. • DNA binding, bending. • RNA polymerase II transcription factor binding. • chromatin DNA binding. ... core promoter binding. • transcription regulatory region sequence-specific DNA binding. • sequence-specific DNA binding. • RNA ... zinc ion binding. • metal ion binding. • RNA polymerase II transcription factor activity, sequence-specific DNA binding. • RNA ...
more infohttps://en.wikipedia.org/wiki/GATA1
RCSB PDB - 1GAT: SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID...  RCSB PDB - 1GAT: SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID...
SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR ... SOLUTION STRUCTURE OF THE SPECIFIC DNA COMPLEX OF THE ZINC CONTAINING DNA BINDING DOMAIN OF THE ERYTHROID TRANSCRIPTION FACTOR ...
more infohttps://www.rcsb.org/3d-view/1GAT?preset=ligandInteraction&sele=ZN
Proximity among distant regulatory elements at the beta-globin locus r by Christopher R. Vakoc, Danielle L. Letting et al.  "Proximity among distant regulatory elements at the beta-globin locus r" by Christopher R. Vakoc, Danielle L. Letting et al.
Together, these data demonstrate that GATA-1 and FOG-1 are essential anchors for a tissue-specific chromatin loop, providing ... By using chromosome conformation capture (3C), we show that the hematopoietic transcription factor GATA-1 and its cofactor FOG- ... suggesting that GATA-1 binding to the promoter and LCR are independent events that occur prior to loop formation. ... Here, we examined the mechanism for DNA looping at the beta-globin locus. ...
more infohttp://escholarship.umassmed.edu/pgfe_pp/132/
Search Articles | University of Toronto Libraries  Search Articles | University of Toronto Libraries
gata2 transcription factor - genetics (172) 172 Filter by. Remove filter. erythroid-specific dna-binding factors (167) 167 ... Transcription Factors - genetics , DNA Primers , DNA-Binding Proteins - genetics , Transcription Factors - metabolism , Animals ... DNA-Binding Proteins - metabolism , Transcription Factors - metabolism , Animals , Transfection , Protein Binding , Cell ... Transcription Factors - genetics , DNA-Binding Proteins - genetics , Gestational Age , Mice, Knockout , Transcription Factors ...
more infohttps://query.library.utoronto.ca/index.php/search/q?kw=SubjectTerms:TRANSCRIPTION%20FACTOR%20GATA-2
Erythroid transcription factor (P15976) | InterPro | EMBL-EBI  Erythroid transcription factor (P15976) | InterPro | EMBL-EBI
GO:0003700 DNA binding transcription factor activity GO:0008270 zinc ion binding GO:0043565 sequence-specific DNA binding ... GO:0006355 regulation of transcription, DNA-templated GO:0030218 erythrocyte differentiation GO:0030219 megakaryocyte ...
more infohttp://www.ebi.ac.uk/interpro/protein/P15976
Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. - MRC Weatherall Institute of Molecular Medicine  Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. - MRC Weatherall Institute of Molecular Medicine
Although loss of GATA-1 leads to differentiation arrest and apoptosis of erythroid progenitors, absence of GATA-1 promotes ... GATA-1 is expressed primarily in hematopoietic cells and is essential for proper development of erythroid cells, megakaryocytes ... GATA-1 is the founding member of a transcription factor family that regulates growth and maturation of a diverse set of tissues ... DNA-Binding Proteins, Down Syndrome, Erythroid-Specific DNA-Binding Factors, GATA1 Transcription Factor, Gene Deletion, Humans ...
more infohttps://www.imm.ox.ac.uk/publications/38957
Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease. - Radcliffe Department of...  Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease. - Radcliffe Department of...
Animals, DNA-Binding Proteins, Disease Models, Animal, Erythroid-Specific DNA-Binding Factors, GATA1 Transcription Factor, Gene ...
more infohttps://www.rdm.ox.ac.uk/publications/267549
Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis...  Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis...
More broadly, there are both species- and regulatory element-specific patterns of transcription factor binding. These findings ... are not conserved in position and sequence and have enhancer activity in erythroid cells. In vivo, they both bind the ... and in vivo binding of transcription factors over approximately 120 kilobases flanking the human GATA1 gene and the ... Human and mouse GATA1 genes encode a critical hematopoietic transcription factor conserved in expression and function. Proper ...
more infohttps://www.rdm.ox.ac.uk/publications/32784
The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome | PNAS  The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome | PNAS
Genes expressed in erythroid cells contain binding sites for a cell-specific nuclear factor, GF-1 (NF-E1, Eryf 1), believed to ... The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome. L I ... The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome ... The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome ...
more infohttps://www.pnas.org/content/87/2/668?ijkey=5a670f5bfbcb7c34c99cb480e66a2253859df726&keytype2=tf_ipsecsha
FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic...  FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic...
Erythroid Precursor Cells/cytology*. *Erythroid Precursor Cells/physiology*. *Erythroid-Specific DNA-Binding Factors ... The hematopoietic transcription factor GATA-1 is essential for development of the erythroid and megakaryocytic lineages. Using ... FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic ... the conserved zinc finger DNA-binding domain of GATA-1 in the yeast two-hybrid system, we have identified a novel, multitype ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/9230307?dopt=Abstract
Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages.  - PubMed - NCBI  Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages. - PubMed - NCBI
Transcription Factors*. *Tumor Cells, Cultured. Substances. *DNA-Binding Proteins. *Erythroid-Specific DNA-Binding Factors ... Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages.. Martin DI1, Zon LI, Mutter G, Orkin ... The nuclear factor GF-1 (also known as NF-E1, Eryf-1; refs 1-3 respectively) is important in regulation of the transcription of ... GF-1 may regulate the transcription of not only erythroid genes, but also many genes characteristic of megakaryocytes and mast ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/2320112?dopt=Abstract
Global regulation of erythroid gene expression by transcription factor GATA-1  - CSHL Scientific Digital Repository  Global regulation of erythroid gene expression by transcription factor GATA-1 - CSHL Scientific Digital Repository
DNA-Binding Proteins Enhancer Elements genetics Erythroblasts Erythroid-Specific DNA-Binding Factors GATA1 Transcription Factor ... Global regulation of erythroid gene expression by transcription factor GATA-1. Blood, 104 (10). pp. 3136-3147. ISSN 00064971 ( ... Transcription factor GATA-1 is required for erythropoiesis, yet its full actions are unknown. We performed transcriptome ... Third, up-regulation of some known GATA-1 targets was delayed, suggesting that auxiliary factors are required. For example, ...
more infohttp://repository.cshl.edu/25396/
Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1  -...  Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1 -...
DNA, DNA-Binding Proteins, Electrophoresis, Polyacrylamide Gel, Erythroid-Specific DNA-Binding Factors, HeLa Cells, Humans, ... DNA, DNA-Binding Proteins, Electrophoresis, Polyacrylamide Gel, Erythroid-Specific DNA-Binding Factors, HeLa Cells, Humans, ... The erythroid transcription factor erythroid factor-1 (EF1) plays a critical role in the transcription of erythroid-specific ... The erythroid transcription factor erythroid factor-1 (EF1) plays a critical role in the transcription of erythroid-specific ...
more infohttps://eprints.soton.ac.uk/411595/
anti-KLF1 antibody [N1], N-term  | GeneTex  anti-KLF1 antibody [N1], N-term | GeneTex
... erythroid)) for WB. Anti-KLF1 pAb (GTX104833) is tested in Human samples. 100% Ab-Assurance. ... erythroid Kruppel-like factor antibody, Krueppel-like factor 1 antibody, erythroid-specific transcription factor EKLF antibody ... The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of- ... Kruppel-like factor 1 (erythroid). Background. This gene encodes a hematopoietic-specific transcription factor that induces ...
more infohttp://www.genetex.com/KLF1-antibody-N1-N-term-GTX104833.html
KLF1 - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad  KLF1 - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
... a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes ... The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of- ... Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer ... Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene ...
more infohttp://www.bio-rad.com/en-us/prime-pcr-assays/assay/qhsaced0003362-primepcr-sybr-green-assay-klf1-human
SOX Transcription Factors | Harvard Catalyst Profiles | Harvard Catalyst  SOX Transcription Factors | Harvard Catalyst Profiles | Harvard Catalyst
Early Growth Response Transcription Factors. *Erythroid-Specific DNA-Binding Factors. *Factor For Inversion Stimulation Protein ... Below are MeSH descriptors whose meaning is more specific than "SOX Transcription Factors". ... Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are ... "SOX Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ...
more infohttps://connects.catalyst.harvard.edu/Profiles/display/Concept/SOX%20Transcription%20Factors
Research Keyword Faculty Listing | Yale School of Medicine  Research Keyword Faculty Listing | Yale School of Medicine
Chromatin Immunoprecipitation; Disease Models, Animal; Erythroid-Specific DNA-Binding Factors; Erythropoiesis; Hematologic ... If you select a health category rather than a specific study, doctors who have active studies in that area may contact you to ... When you express interest in a specific study, the information from your profile will be sent to the doctor conducting that ...
more infohttps://medicine.yale.edu/research/listing.aspx?meshId=6284
Research Keyword Faculty Listing | Yale School of Medicine  Research Keyword Faculty Listing | Yale School of Medicine
Chromatin Immunoprecipitation; Disease Models, Animal; Erythroid-Specific DNA-Binding Factors; Erythropoiesis; Hematologic ... If you select a health category rather than a specific study, doctors who have active studies in that area may contact you to ... When you express interest in a specific study, the information from your profile will be sent to the doctor conducting that ...
more infohttps://medicine.yale.edu/research/listing.aspx?meshId=6127