Megakaryocyte-erythroid progenitor cells, among other blood cells, are generated as a result of hematopoiesis, which occurs in ... Hematopoietic stem cells can differentiate into one of two progenitor cells: the common lymphoid progenitor and the common ... Most of the blood cells produced in the bone marrow during hematopoiesis come from megakaryocyte/erythrocyte progenitor cells. ... "Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation". Blood. 133 (13): 1427- ...

Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion Blood Adv. 2020 Dec 8;4(23):5915-5924. ... to promote erythroid cell expansion. Finally, using the kita mutant (kitab5/b5 or sparse), we show that the Kita receptor is ... crucial for Kitlga/b cooperation with Epo in erythroid cells. In summary, using optimized suspension culture conditions with ... and we demonstrate that Kitlga is necessary for expansion of erythroid progenitors ex vivo. To further address the role of ...

The TER-119 antigen is expressed on erythroid cells from pro-erythroblast through mature erythrocyte stages, but not on cells ... The TER-119 antigen is expressed on erythroid cells from pro-erythroblast through mature erythrocyte stages, but not on cells ... The TER-119 epitope is not detected on hematopoietic stem cells, lymphoid cells, myeloid cells, or erythroleukemia lines. The ... The TER-119 epitope is not detected on hematopoietic stem cells, lymphoid cells, myeloid cells, or erythroleukemia lines. The ...

US-2019062788-A1 chemical patent summary.

Purified anti-mouse TER-119/Erythroid Cells Antibody - The TER-119 antigen is a 52 kD glycophorin A-associated protein, also ... PE/Cyanine5 anti-mouse TER-119/Erythroid Cells. TER-119. FC. Purified anti-mouse TER-119/Erythroid Cells. TER-119. FC,IHC-F,IHC ... TotalSeq™-A0122 anti-mouse TER-119/Erythroid Cells. TER-119. PG. APC/Fire™ 750 anti-mouse TER-119/Erythroid Cells. TER-119. FC ... TotalSeq™-B0122 anti-mouse TER-119/Erythroid Cells. TER-119. PG. TotalSeq™-C0122 anti-mouse TER-119/Erythroid Cells. TER-119. ...

Enucleation, Hemoglobin, HPV-E6/E7, Immortalized erythroid cell lines, Red blood cells. in Human Cell. volume. 35. issue. 1. ... Through simply changing cell culture conditions, a newly established cell line, Erythroid Line from Lund University (ELLU), is ... Through simply changing cell culture conditions, a newly established cell line, Erythroid Line from Lund University (ELLU), is ... Ex vivo manufactured red blood cells (RBC) generated from immortalized erythroid cell lines which can continuously grow are ...

Protein 4.1 is a peripheral membrane protein that strengthens the actin-spectrin based membrane skeleton of the red blood cell ... This modulation may permit the assembly of an initially flexible membrane skeleton in mitotic erythroid cells. As cells become ... During erythroid terminal differentiation the molar amounts of protein 4.1 and spectrin assembled change. In postmitotic cells ... M Staufenbiel, E Lazarides; Assembly of protein 4.1 during chicken erythroid differentiation.. J Cell Biol 1 April 1986; 102 (4 ...

"Erythroid progenitor cell reprogrammed to MDSC-like immune suppressive cells in late-stage cancer." In European Journal of ... Erythroid progenitor cell reprogrammed to MDSC-like immune suppressive cells in late-stage cancer. Publication , Conference ... "Erythroid progenitor cell reprogrammed to MDSC-like immune suppressive cells in late-stage cancer." European Journal of ... Long H, Wang Z, Li Q-J, Zhu B. Erythroid progenitor cell reprogrammed to MDSC-like immune suppressive cells in late-stage ...

Furthermore, we posit that this erythrocyte cell signature may be linked to a population of immunosuppressive erythroid cells ... Definition of erythroid cell‐positive blood transcriptome phenotypes associated with severe respiratory syncytial virus ... Darawan Rinchai, Matthew C Altman, Oceane Konza, Signe Hässler, Federica Martina, et al.. Definition of erythroid cell‐positive ... "cell cycle" (CC), and "erythrocytes" (Ery). We identified eight prevalent blood transcriptome phenotypes, of which three Ery+ ...

These findings suggest that parasite proteins are able to inhibit erythroid cell growth by down-regulation of ezrin ... In previously reports, Plasmodium vivax was found to be able to directly inhibited erythroid cell proliferation and ... This result suggests that phospho-ezrin is important for actin cytoskeleton regulation during erythroid cell growth and ... This study describes the first comparative phosphoproteome analysis of growing erythroid cells (gECs), derived from human ...

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Advances. 2019 May 28;3( ... The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. In: Blood Advances. 2019 ; Vol ... Our study implicates SPOP and the CUL3 ubiquitin ligase system in controlling HbF production in human erythroid cells and may ... Our study implicates SPOP and the CUL3 ubiquitin ligase system in controlling HbF production in human erythroid cells and may ...

The present study investigated the effects of PQS on the calcification of vascular smooth muscle cell (VSMCs). The present ... The intracellular reactive oxygen species (ROS) levels and the transcriptional activity of nuclear factor-erythroid 2-related ... Panax quinquefolius saponin inhibits vascular smooth muscle cell calcification via activation of nuclear factor-erythroid 2- ... Panax quinquefolius saponin inhibits vascular smooth muscle cell calcification via activation of nuclear factor-erythroid 2- ...

... BONVICINI, FRANCESCA;BUA, GLORIA;CONTI, ILARIA; ... Parvovirus B19 (B19V) infection is restricted to erythroid progenitor cells (EPCs) of the human bone marrow, leading to ... Parvovirus B19 (B19V) infection is restricted to erythroid progenitor cells (EPCs) of the human bone marrow, leading to ... the UT7/EpoS1 cell line and EPCs. Results demonstrate that HU inhibits B19V replication with EC50 values of 96.2μM and 147.1μM ...

Expression profile of healthy erythroid progenitors Merryweather-Clarke AT., Atzberger A., Shah W., Woffendin HB., Soneji S., ...

TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells. / Kramer, Ashley C.; Weber, Jenna; Zhang, Ying et al. In: Stem Cell ... TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells. Stem Cell Reports. 2017 Feb 14;8(2):360-372. doi: 10.1016/j.stemcr. ... TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells. In: Stem Cell Reports. 2017 ; Vol. 8, No. 2. pp. 360-372. ... TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells. Ashley C. Kramer, Jenna Weber, Ying Zhang, Jakub Tolar, Ying Y. ...

Lipid composition of Friend leukemia cells following induction of erythroid differentiation by dimethyl sulfoxide. Journal of ... Lipid composition of Friend leukemia cells following induction of erythroid differentiation by dimethyl sulfoxide. In: Journal ... Dive into the research topics of Lipid composition of Friend leukemia cells following induction of erythroid differentiation ... Lipid composition of Friend leukemia cells following induction of erythroid differentiation by dimethyl sulfoxide. / Rittmann, ...

... represent clonal hematopoietic stem cell disorders resulting in ineffective hematopoiesis. Refractory anemia with ring ... Dysplastic features of nucleated erythroid precursors. Cells are disproportionately large, corresponding to the normal stage of ... Most often, the bone marrow is hypercellular with a significant increase in erythroid precursors. At least 10% of the erythroid ... although an increased percentage of CD34 cells would not be seen in RARS, an absence of CD34+ cells does not exclude a higher- ...

abnormal megakaryocyte-erythroid progenitor cell morphology. go back to main search page ... any structural anomaly of a progenitor cell committed to the megakaryocyte and erythroid lineages. ... Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data ... abnormal colony forming unit erythroid megakaryocyte morphology; abnormal megakaryocyte/erythrocyte progenitor morphology. ...

The vacuoles usually occur in early erythroid cells as seen here and very occasionally in myeloid cells. They may be observed ... Abnormal Erythroid Precursor Cells. In: MA L, MS S, RE F, N W. MA L, & MS S, & RE F, & N W(Eds.),Eds. Lichtman MA, et al.eds. ... "Abnormal Erythroid Precursor Cells." Lichtmans Atlas of Hematology 2016 MA L, MS S, RE F, N W. MA L, & MS S, & RE F, & N W(Eds ... Abnormal erythroid precursor cells. MA L, MS S, RE F, N W. MA L, & MS S, & RE F, & N W(Eds.),Eds. Lichtman MA, et al. (2017). ...

... in erythroid cells. MYEF2 is bound in undifferentiated cells and is lost upon differentiation, whereas LSD1 is bound in ... in erythroid cells. We used a tagging strategy to show that RUNX1 interacts with two novel protein partners, LSD1 and MYEF2, ... and microarray expression analysis were used to show that RUNX1 binds approximately 9,000 target sites in erythroid cells and ... RUNX1 is known to be an essential transcription factor for generating hematopoietic stem cells (HSC), but much less is known ...

... in human macrophage/erythroid cell cocultures. Coculture of human bone marrow endothelial cells with erythroid progenitor cells ... in human macrophage/erythroid cell cocultures. Coculture of human bone marrow endothelial cells with erythroid progenitor cells ... in human macrophage/erythroid cell cocultures. Coculture of human bone marrow endothelial cells with erythroid progenitor cells ... Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production. ...

... in erythroid cells it represses cell proliferation and early hematopoietic genes while activating erythroid genes, yet it is ... Using a biotinylation tagging/proteomics approach in erythroid cells, we describe distinct GATA-1 interactions with the ... Based on these findings, we suggest a model for the different roles of GATA-1 in erythroid differentiation. ... eosinophilic and mast cell lineages. It acts as an activator and repressor of different target genes, for example, ...

Characterization of the YN‐1 and Y‐1K cells revealed that these cells expressed erythroid lineage markers. However, there was a ... Characterization of the YN‐1 and Y‐1K cells revealed that these cells expressed erythroid lineage markers. However, there was a ... Characterization of the YN‐1 and Y‐1K cells revealed that these cells expressed erythroid lineage markers. However, there was a ... Characterization of the YN‐1 and Y‐1K cells revealed that these cells expressed erythroid lineage markers. However, there was a ...

Sox6-overexpression in K562 cells and in human primary ex vivo erythroid cultures enhances erythroid differentiation and leads ... Sox6-overexpression in K562 cells and in human primary ex vivo erythroid cultures enhances erythroid differentiation and leads ... Sox6-overexpression in K562 cells and in human primary ex vivo erythroid cultures enhances erythroid differentiation and leads ... Sox6-overexpression in K562 cells and in human primary ex vivo erythroid cultures enhances erythroid differentiation and leads ...

Congenital erythroid hypoplastic anemia. *Congenital hypoplastic anemia of Blackfan and Diamond. *Congenital pure red cell ... regulating cell division. , and controlling the self-destruction of cells (apoptosis. ). ... Ribosomes process the cells genetic instructions to create proteins.. Each ribosome is made up of two parts (subunits) called ... Abnormal regulation of cell division or inappropriate triggering of apoptosis may contribute to the other health problems that ...

A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells. In: ... A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells. ... A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells. / ... A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells. ...

... colony-forming-unit-erythroid), were isolated to practical homogeneity by a combination of three enrichment procedures. CFU-E ... These cells enable us to study the biochemical changes occurring in the differentiation process of an erythroid progenitor cell ... W Nijhof, P K Wierenga; Isolation and characterization of the erythroid progenitor cell: CFU-E.. J Cell Biol 1 February 1983; ... Erythroid progenitor cells, CFU-E (colony-forming-unit-erythroid), were isolated to practical homogeneity by a combination of ...

Regulation of c-jun mRNA expression by hydroxyurea in human K562 cells during erythroid differentiation.. ... Regulation of c-jun mRNA expression by hydroxyurea in human K562 cells during erythroid differentiation.. ...

plate 50.000 transduced CD34+ cells in 4 ml Iscoves modified Dulbeccos medium (IMDM, Gibco-Life technologies) in the presence ... Erythroid differentiation: Epo (3 U/ml), IL-3 (0.01 U/ml), GM-CSF (0.001 ng/ml) ...

... but not erythroid and megakaryocytic cells in vitro. These results identify FOG-1 and GATA-1 as required for formation of ... Finally, C/EBPs and FOG-1 exhibited transcriptional cross-regulation in early myelo-erythroid progenitors making their ... whereas transcriptional control of erythroid (E) and megakaryocytic (Mk) fate is less understood. We here use conditional ... The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for ...