Equilibrative nucleoside transporter 2 - Wikipedia
Solute carrier family Equilibrative nucleoside transporters Nucleoside transporters GRCh38: Ensembl release 89: ENSG00000174669 ... Equilibrative nucleoside transporter 2 (ENT2) is a protein that in humans is encoded by the SLC29A2 gene. ... 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Arch. 447 (5): 735-43. doi:10.1007/s00424-003-1103-2 ... Mangravite LM, Xiao G, Giacomini KM (2003). "Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in ...
The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with...
Since the equilibrative nucleoside transporter-2 (Ent2) is important in regulating brain adenosine homeostasis, the present ... The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with ...
Deletion of equilibrative nucleoside transporter-2 protects against lipopolysaccharide-induced neuroinflammation and blood...
Table of Contents - April 01, 2005, 67 (4) | Molecular Pharmacology
Residue 33 of Human Equilibrative Nucleoside Transporter 2 Is a Functionally Important Component of Both the Dipyridamole and ... Molecular Determinants of Substrate/Inhibitor Binding to the Human and Rabbit Renal Organic Cation Transporters hOCT2 and ... Nucleoside Binding Sites Frank Visser, Jing Zhang, R. Taylor Raborn, Stephen A. Baldwin, James D. Young and Carol E. Cass ... β-Arrestin 2-Dependent Angiotensin II Type 1A Receptor-Mediated Pathway of Chemotaxis Dacia L. Hunton, William G. Barnes, Jihee ...
Histiocytosis-lymphadenopathy plus syndrome: MedlinePlus Genetics
Human equilibrative nucleoside transporter-3 (hENT3) spectrum disorder mutations impair nucleoside transport, protein ... Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome ( ... which provides instructions for making a protein called equilibrative nucleoside transporter 3 (ENT3). ENT3 belongs to a family ... A lack of ENT3 activity may also lead to a reduction in the amount of nucleosides in mitochondria. This nucleoside shortage ...
Chemistry and Biochemistry - Scholarly Works - University of Arizona
Predicting drug interactions with human equilibrative nucleoside transporters 1 and 2 using functional knockout cell lines and ... Purine Nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells. Islinger, F., Gekle, M. & ... Physiological Characterization of the Transporter-Mediated Uptake of the Reversible Male Contraceptive H2-Gamendazole across ... Weyand, N. J., Calton, C. M., Higashi, D. L., Kanack, K. J. & So, M., Jan 15 2010, In: Journal of Immunology. 184, 2, p. 694- ...
VAL-0914 Decreases PAO to Protect Against Cardiac Proteinopathies - Robert Shaffer
6 mercaptopurine. Medical search
Equilibrative nucleoside transporter 1. ... mercaptopurine riboside] and dilazep for the human equilibrative nucleoside ... Anticancer nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside.... ... nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside transporter 2. ( ... 6-thioguanine nucleosides (6-TGNs), 6-methylmercaptopurine, and 6-methylmercaptopurine nucleosides (6-MMPNs). (nih.gov) ...
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Aberrant bone density in aging mice lacking the adenosine transporter ENT1<...
Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma ... Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma ... Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma ... Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma ...
Two novel nucleobase/pentamidine transporters from Trypanosoma brucei<...
The Trypanosoma brucei genome project has identified 12 members of the equilibrative nucleoside transporter family, most of ... The Trypanosoma brucei genome project has identified 12 members of the equilibrative nucleoside transporter family, most of ... The Trypanosoma brucei genome project has identified 12 members of the equilibrative nucleoside transporter family, most of ... The Trypanosoma brucei genome project has identified 12 members of the equilibrative nucleoside transporter family, most of ...
ALCOHOL REPORTS: 4/4/10 - 4/11/10
Equilibrative nucleoside transporter 1 (ENT1) and excitatory amino acid transporter 2 (EAAT2) are predominantly expressed in ... Studies performed in cell cultures suggest that ethanol inhibits equilibrative nucleoside transporter 1 to block the reuptake ... The purine nucleoside, adenosine, is responsible for mediating many neuronal and behavioral responses to ethanol. ... Experiments 1 and 2 demonstrated a direct relationship between β-E levels and immobility. There were also sex differences in ...
IJMS | Free Full-Text | Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer
Carrier, E.J.; Auchampach, J.A.; Hillard, C.J. Inhibition of an equilibrative nucleoside transporter by cannabidiol: A ... by binding to equilibrative nucleoside transporter-1); inhibition ofG-protein coupled receptor 55 (GPR55); and the stimulation ... showed that CBD acts as a inhibitor of adenosine and thiamine uptake by inhibiting the equilibrative nucleoside transporter-1 ( ... the purine nucleoside, adenosine, is secreted by cancer and immune cells under metabolic stress and hypoxia [130]. Adenosine ...
Plus it
An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit m1, ribonucleoside reductase ... Capecitabine was dosed at 1,600 mg/m2/day in two divided doses per day (median dose=1,600 mg/m2/day) based on our phase I study ... 2Hofstra North Shore LIJ School of Medicine, North Shore LIJ Health System, New Hyde Park, New York, NY, U.S.A. ... This was combined with either 4 months of gemcitabine at 1,000 mg/m2 weekly for 3 out of 4 weeks or capecitabine at 2,000 mg/m2 ...
Cytarabine (Ara-C) is an initial range clinical therapeutic agent for treatment - PI3K Signaling in B and T Lymphocytes
3the human being equilibrative nucleoside transporter 1 (hENT1), and it is eventually phosphorylated to cytarabine-triphosphate ... The cytotoxicity of Ara-C in the Mnk1&2 KD cells was improved by 10-fold in comparison to WT cells (Desk ?(Desk2).2). Also, the ... Alternatively, Ara-C activates the MAPK-Mnk-eIF4E pathway by causing the phosphorylation of Erk1/2, p38 and eIF4E, leading to a ... MNKI-8e is normally a powerful and selective Mnk inhibitor in comparison to known Mnk inhibitors, phosphorylation of Erk1/2, ...
SLC29A2-H154B-Wuxi Biortus Biosciences Co. Ltd.
Equilibrative NBMPR-insensitive nucleoside transporter,Hydrophobic nucleolar protein, 36 kDa,Nucleoside transporter, ei-type, ... Alias: Equilibrative nucleoside transporter 2,36 kDa nucleolar protein HNP36,Delayed-early response protein 12,Equilibrative ... Background: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less ...
Topical CBD for Pain | Natural Medicine Journal
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proc Natl ... 1998;280(2):147-151.. *Smith BH, Elliott AM, Chambers WA, et al. The impact of chronic pain in the community. Fam Pract. 2001; ... 2009;30(2):79-84.. *Klein TW, Newton C, Larsen K, et al. The cannabinoid system and immune modulation. J Leukoc Biol. 2003;74(4 ... 2002;241(2):329-339.. *Lodzki M, Godin B, Rakou L, et al. Cannabidiol-transdermal delivery and anti-inflammatory effect in a ...
RCSB PDB - P0T Ligand Summary Page
Equilibrative nucleoside transporter 1. MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVS.... unknown. inhibitor. P- ... InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-, ... 2-[(1~{R},6~{R})-3-methyl-6-prop-1-en-2-yl-cyclohex-2-en-1-yl]-5-pentyl-benzene-1,3-diol. ... Indoleamine 2,3-dioxygenase 1. MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLI.... unknown. inhibitor. Cytochrome P450 1B1. ...
The gradual drop in -cell function is inevitable in type 2 - Stem cell application on skin cancer research
Equilibrative Nucleoside Transporters *ER *ErbB *ERK *ERR *Esterases *Estrogen (GPR30) Receptors *Estrogen Receptors ... Dipeptidyl peptidase-4 inhibitors (DPP-4I) and sodium-glucose co-transporter-2 inhibitors (SGLT-2I) are various other exciting ... The gradual drop in -cell function is inevitable in type 2. * Post author By exposed ... The gradual drop in -cell function is inevitable in type 2 diabetes mellitus and for that reason, substantial proportions of ...
Human Equilibrative nucleoside transporter 1 ELISA Kit - Biotechnolabs
Human Equilibrative nucleoside transporter 1 ELISA Kit Biotechnolabs Elisa Kit, Molecular Biology, Plant and Animal Antibodies ... equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 1; equilibrative nucleoside transporter 1; solute ... equilibrative nucleoside transporter), member 1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive Gene Name. [SLC29A1 ... Human Equilibrative nucleoside transporter 1 ELISA Kit. Synonym. [Equilibrative nucleoside transporter 1]. ...
MH DELETED MN ADDED MN
Equilibrative Nucleoside Transporter 1 D12.776.157.530.937.532.500 D12.776.543.585.937.563.500 Equilibrative-Nucleoside ... Equilibrative Nucleoside Transport Proteins D12.776.157.530.937.532 D12.776.543.585.937.563 ... Cationic Amino Acid Transporter 1 D12.776.157.530.937.375.200 D12.776.543.585.937.375.200 Cationic Amino Acid Transporter 2 ... Glucose Transporter Type 1 D12.776.157.530.937.563.500 D12.776.543.585.937.625.500 Glucose Transporter Type 2 D12.776.157.530. ...
MH DELETED MN ADDED MN
Equilibrative Nucleoside Transporter 1 D12.776.157.530.937.532.500 D12.776.543.585.937.563.500 Equilibrative-Nucleoside ... Equilibrative Nucleoside Transport Proteins D12.776.157.530.937.532 D12.776.543.585.937.563 ... Cationic Amino Acid Transporter 1 D12.776.157.530.937.375.200 D12.776.543.585.937.375.200 Cationic Amino Acid Transporter 2 ... Glucose Transporter Type 1 D12.776.157.530.937.563.500 D12.776.543.585.937.625.500 Glucose Transporter Type 2 D12.776.157.530. ...
MH DELETED MN ADDED MN
Equilibrative Nucleoside Transporter 1 D12.776.157.530.937.532.500 D12.776.543.585.937.563.500 Equilibrative-Nucleoside ... Equilibrative Nucleoside Transport Proteins D12.776.157.530.937.532 D12.776.543.585.937.563 ... Cationic Amino Acid Transporter 1 D12.776.157.530.937.375.200 D12.776.543.585.937.375.200 Cationic Amino Acid Transporter 2 ... Glucose Transporter Type 1 D12.776.157.530.937.563.500 D12.776.543.585.937.625.500 Glucose Transporter Type 2 D12.776.157.530. ...
MH DELETED MN ADDED MN
Equilibrative Nucleoside Transporter 1 D12.776.157.530.937.532.500 D12.776.543.585.937.563.500 Equilibrative-Nucleoside ... Equilibrative Nucleoside Transport Proteins D12.776.157.530.937.532 D12.776.543.585.937.563 ... Cationic Amino Acid Transporter 1 D12.776.157.530.937.375.200 D12.776.543.585.937.375.200 Cationic Amino Acid Transporter 2 ... Glucose Transporter Type 1 D12.776.157.530.937.563.500 D12.776.543.585.937.625.500 Glucose Transporter Type 2 D12.776.157.530. ...
MH DELETED MN ADDED MN
Equilibrative Nucleoside Transporter 1 D12.776.157.530.937.532.500 D12.776.543.585.937.563.500 Equilibrative-Nucleoside ... Equilibrative Nucleoside Transport Proteins D12.776.157.530.937.532 D12.776.543.585.937.563 ... Cationic Amino Acid Transporter 1 D12.776.157.530.937.375.200 D12.776.543.585.937.375.200 Cationic Amino Acid Transporter 2 ... Glucose Transporter Type 1 D12.776.157.530.937.563.500 D12.776.543.585.937.625.500 Glucose Transporter Type 2 D12.776.157.530. ...
Germán Morong Reyes scite author profile
Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. Grenz1, ... Consistent with the notion that equilibrative nucleoside transporters (ENTs) terminate adenosine signaling, we observed that ... 2) a design exercise with VR professionals to explore possible notification methods; and 3) an empirical study on the ... 2, 3). Particularly for surgical patients, AKI represents a significant threat. For example, surgical procedures requiring ...
"sequence id","alias","species","description",...
"Equilibrative nucleoside transporter 3","protein_coding" "Sro1204_g252200.1","Contig1757.g15595","Seminavis robusta","PI-PLC X ... "Equilibrative nucleoside transporter [Interproscan].","protein_coding" "SymbC1.scaffold3742.4","3742.4","Cladocopium sp. clade ... ","ABC transporter-like; ABC-transporter extension domain [Interproscan].","protein_coding" "SymbC1.scaffold8376.4","8376.4"," ... ","ABC transporter-like; ABC-transporter extension domain [Interproscan].","protein_coding" "TP13G01420.1","No alias"," ...
bromo-deaza-SAH | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/ ... Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3 ... Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Sodium/nucleoside cotransporter 2 ... Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Plasma ...
Best CBD Oil for Migraines & Headaches: Benefits, Dosage, & Side-Effects
Carrier, E. J., Auchampach, J. A., & Hillard, C. J. (2006). Inhibition of an equilibrative nucleoside transporter by ... 2. Inhibits Brain Inflammation. One of the ways marijuana was used in the past to treat headaches, was by wrapping its wet ... Phase 2: Aura Phase. During the aura phase, people experience strange changes in their vision and/or perception. It can change ... 2. Inflammation (Sensitization). We need inflammation to stay healthy.. Its our bodies way to trap and destroy invading ...