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*  Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes. -...
... indicating that these genes are not involved in inhibition of antigen presentation of the epitopes tested. ... inhibits the presentation of certain epitopes from influenza virus nucleoprotein (NP), haemagglutinin (HA) and non-structural 1 ... Vaccinia virus (VV) inhibits the presentation of certain epitopes from influenza virus nucleoprotein (NP), haemagglutinin (HA) ... indicating that these genes are not involved in inhibition of antigen presentation of the epitopes tested. ...
https://www.rdm.ox.ac.uk/publications/16717
*  Oxidation-Specific Epitopes in Human Coronary Atherosclerosis Are Not Limited to Oxidized Low-Density Lipoprotein | Circulation
Formation of Oxidation Epitopes In Vitro. To determine the conditions under which Ox5 epitopes might be formed on proteins in ... Finally, epitopes recognized by Ox5 can be formed on human monocyte-derived macrophages in vitro. The presence of Ox5 epitopes ... Oxidation-Specific Epitopes Can Be Formed on Human Proteins Exposed to Polyunsaturated Fatty Acid Emulsions. Ox5 epitopes were ... Furthermore, the antibody recognized an oxidized phospholipid epitope rather than a protein epitope, so it is possible that the ...
http://circ.ahajournals.org/content/94/6/1216
*  Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection. - Radcliffe Department of Medicine
METHODS: We have used soluble tetrameric complexes of HLA class I molecules complexed with HIV epitope peptides to study the ... METHODS: We have used soluble tetrameric complexes of HLA class I molecules complexed with HIV epitope peptides to study the ...
https://www.rdm.ox.ac.uk/publications/3639
*  Defective Ribosomal Products Are the Major Source of Antigenic Peptides Endogenously Generated from Influenza A Virus...
Cutting edge: neosynthesis is required for the presentation of a T cell epitope from a long-lived viral protein. J. Immunol. ... Identification of a novel tumor-specific CTL epitope presented by RMA, EL-4, and MBL-2 lymphomas reveals their common origin. J ... N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase. J. Immunol. 182: 4830-4835. ... NA stability of enzymatic activity is unaffected by the SIINFEKL epitope. A, DC2.4 cells were infected with the indicated virus ...
http://www.jimmunol.org/content/184/3/1419.long
*  A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins
... the epitope must be processed from polypeptides that have never reached the ER. The processing of this epitope depends on the ... the epitope must be processed from polypeptides that have never reached the ER. The processing of this epitope depends on the ... Here, we show that an HLA-A(*)0201-restricted epitope from prostate stem cell antigen contains the cleavage site of the ER ... Here, we show that an HLA-A(*)0201-restricted epitope from prostate stem cell antigen contains the cleavage site of the ER ...
https://kops.uni-konstanz.de/handle/123456789/1202
*  IEDB.org: Free epitope database and prediction resource
Includes more than 95% of all published infectious disease, allergy, autoimmune, and transplant epitope data. ... Free resource for searching and exporting immune epitopes. ...
http://www.iedb.org
*  Cryptic self epitopes - Wikipedia
In immunology, cryptic self epitopes are a source of autoimmunity. Self epitopes, which are found in high concentration on the ... However, self epitopes which appear in very low concentration on APC are termed cryptic in the sense that they do not delete ... Lanzavecchia, A (1995). "How can cryptic epitopes trigger autoimmunity?" (PDF). J. Exp. Med. 181: 1945-8. doi:10.1084/jem.181.6 ... are known as dominant epitopes. These are stimulants of negative selection mechanisms to remove potentially self destructing ...
https://en.wikipedia.org/wiki/Cryptic_self_epitopes
*  Epitope - Wikipedia
The epitopes of protein antigens are divided into two categories, conformational epitopes and linear epitopes, based on their ... A database of B-cell epitopes SYFPEITHI - First online database of T cell epitopes IEDB - Database of T and B cell epitopes ... A linear epitope is formed by a continuous sequence of amino acids from the antigen. T cell epitopes are presented on the ... The proportion of epitopes that are conformational is unknown.[citation needed] By contrast, linear epitopes interact with the ...
https://en.wikipedia.org/wiki/Epitope
*  epitope - Wiktionary
epitope (plural epitopes). *(biochemistry) That part of a biomolecule (such as a protein) that is the target of an immune ... Retrieved from "https://en.wiktionary.org/w/index.php?title=epitope&oldid=43030729" ...
https://en.wiktionary.org/wiki/epitope
*  T-cell epitopes
... BRAIN ROBERTSON robertson at mpib-tuebingen.mpg.dbp.de Tue Oct 20 03:32:52 EST 1992 *Previous message: ... Dear Netters, Does anyone know of any software for the prediction of T-cell epitopes from peptide sequences? I have access to ...
http://www.bio.net/bionet/mm/bio-soft/1992-October/003226.html
*  Epitope mapping - Wikipedia
Linear epitopes are formed by a continuous sequence of amino acids in a protein, while conformational epitopes are composed of ... Epitope mapping is the process of experimentally identifying the binding sites, or 'epitopes', of antibodies on their target ... Epitope mapping is also crucial to developing vaccines against prevalent viral diseases such as Dengue virus. Epitope mapping ... "Epitope Mapping". www.covalx.com/epitope2. Retrieved 2017-02-23. Epitope mapping at the US National Library of Medicine Medical ...
https://en.wikipedia.org/wiki/Epitope_mapping
*  Linear epitope - Wikipedia
A linear or a sequential epitope is an epitope that is recognized by antibodies by its linear sequence of amino acids, or ... Such segments are called epitopes. Likewise, it is only paratope of the antibody that comes in contact with the epitope. ... Therefore, antibodies that recognize linear epitopes instead of conformational epitopes are chosen for immunodetection. In ... antibodies are preferred that recognize conformational epitopes. Conformational epitope Polyclonal B cell response Goldsby, ...
https://en.wikipedia.org/wiki/Linear_epitope
*  Conformational epitope - Wikipedia
These are known as linear epitopes. Antigen Linear epitope Epitope mapping, finding (on an antigen protein) the epitope(s) for ... Such segments are called epitopes. Likewise, it is only paratope of the receptor that comes in contact with the epitope. ... A conformational epitope is a sequence of sub-units (usually amino acids) composing an antigen that come in direct contact with ... a new method to predict conformational epitopes using phage display peptide sequences. ...
https://en.wikipedia.org/wiki/Conformational_epitope
*  Epitope binning - Wikipedia
Epitope binning is referenced in the literature under different names such as epitope mapping and epitope characterization. ... Epitope Binning is used in the discovery and development of new therapeutics, vaccines, and diagnostics. Autoimmunity Epitope ... Epitope binning is a competitive immunoassay used to characterize and then sort a library of monoclonal antibodies against a ... Closely related binning profiles indicate that the antibodies have the same or a closely related epitope and are "binned" ...
https://en.wikipedia.org/wiki/Epitope_binning
*  Hepatitis C virus epitopes - Genelabs Incorporated
10 shows an epitope map of the HCV capsid protein region. FIGS. 11A to 11H present a DNA sequence corresponding to the sequence ... An epitope map of the HCV capsid region is presented in FIG. 10: the location of the protein coding sequences corresponding to ... An epitope map of the HCV capsid region is presented in FIG. 10: the location of the immunoreactive protein coding sequences ... The region comprising the first 35 amino acids spans one of the epitopes and the region spanning residues 34-90 encompasses the ...
http://www.freepatentsonline.com/5443965.html
*  Epitope | Definition | AIDSinfo
Epitope Epitope Speaker A specific area on the surface of an antigen that interacts with and binds to specific antibodies. ... Generally, an antigen has several different epitopes. ...
https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/238/epitope
*  Prediction of T cell epitopes
Finding epitopes in real proteins. You shall use the neural network to find potential epitopes in the Sars virus. In the ... Q20: How many high binding epitopes do you find? Is this number reasonable (how large a fraction of random 9meric peptides are ... Also you have identified potential CTL epitope vaccine candidates for the SARS virus. All you need now is to find some venture ... Prediction of T cell epitopes. Overview. During this exercise you will use bioinformatics tools to predict peptide-MHC binding ...
http://www.cbs.dtu.dk/courses/27685.imm/exercise_MHC_bind/exercise_2010.php
*  Linear ``||´ ´ Conformational ``||´´ Epitope ` `||´´ Retrieval
already done , , It is likely not the case, but theoretically your epitope still can be , conformational - protein can refold ... Linear_``,,´ ´_Conformational_``,,´´_Epitope _ ` `,,´´_Retrieval. redeamer alion85 at hotmail.com Tue Feb 10 16:37:16 EST 2004 ... after linear epitope mapping is completed ... then i wont have any feeling at all just plain persuadive data:) , , , Peter , ... Previous message: ``,,´´_Linear_``,,´ ´_Conformational_``,,´´_Epitope_ ` `,,´´_Retrieval *Next message: Everywhere life is full ...
http://www.bio.net/bionet/mm/methods/2004-February/097776.html
*  Immune Epitope Database and Analysis Resource - Wikipedia
... which contains a collection of tools to predict and analyze epitopes. Immune Epitope Database IEDB Analysis Resource La Jolla ... The Immune Epitope Database and Analysis Resource (IEDB) is a project hosted by scientists at the La Jolla Institute for ... In addition, epitopes from other infectious agents, allergens and autoantigens are being curated. The database also contains ... The IEDB contains data related to antibody and T cell epitopes for humans, non-human primates, rodents, and other animal ...
https://en.wikipedia.org/wiki/Immune_Epitope_Database_and_Analysis_Resource
*  epitope tag: two or one?
Guy Oshiro wrote: , , It is commone to repeat the epitope tag. It is common to see 3xHA tags , and 9xMyc tags in the literture ... epitope tag: two or one?. Darren A. Natale dnatale at box-d.nih.gov.nospam Thu Jun 18 09:13:26 EST 1998 *Previous message: ...
http://www.bio.net/bionet/mm/methods/1998-June/067931.html
*  ePitope Informatics Ltd
... Top Floor. 11 Market Street. Hexham, Not Applicable NE46 3NS ENGLAND Phone: +44-1434-609962. Website: ... http://www.epitope-informatics.com. E-mail: info@epitope-informatics.com. View Product Categories. ...
http://www.biosupplynet.com/cfdocs/suppliers/supp_det.cfm?supp_id=12558
*  Predicting MHC class I epitopes i... preview & related info | Mendeley
Roomp, K., Antes, I., & Lengauer, T. (2010). Predicting MHC class I epitopes in large datasets. BMC Bioinformatics, 11. https ... I prediction methods on comparatively large HLA-A and HLA-B allele peptide binding datasets extracted from the Immune Epitope ...
https://www.mendeley.com/catalogue/predicting-mhc-class-i-epitopes-large-datasets/
*  Development of Vaccines by Grafting Microbial Epitopes in Immunoglobulins | SpringerLink
Influenza Virus Cell Epitope 2PK3 Cell Internal Image Foreign Epitope These keywords were added by machine and not by the ... Townsend, A.R.M., Rothbard, J., Gotch, F.M., Bahadur, G., Wraith, D., and McMichael, A.J. (1986). The epitopes of influenza ... Zaghouani, H., Steinman, R., Nonacs, R., Shah, H., Gerhard, W. and Bona, C. (1993). Presentation of a viral T cell epitope ... Bona C.A. (1994) Development of Vaccines by Grafting Microbial Epitopes in Immunoglobulins. In: Kurstak E. (eds) Modern ...
https://link.springer.com/chapter/10.1007/978-1-4899-1450-7_3
*  Hu: Unmasking Conserved Epitopes
Unmasking conserved epitopes on HIV envelope protein for vaccine design. Grant Award. Up to $7.7 million, awarded October 2011 ... Removal of the N7 glycan modified the epitope specificity of the Ab responses; but did not improve the titer or the breadth of ... Hu: Unmasking Conserved Epitopes. OVERVIEW. A vaccine capable of generating broadly neutralizing antibodies (bNAbs) against ... We are currently completing the analysis of the functional antibody responses and the epitope specificity of the cross-reactive ...
https://www.cavd.org/grantees/Pages/Grantee-Hu.aspx
*  Cellular immune response to cryptic epitopes during therapeutic gene transfer. - PubMed - NCBI
OVA epitope presentation in the F9 ARF1. (A) The activation of spleen cells from OT-1 mice by OVA epitope presentation. Cos/Kb ... CTL responses to epitopes from the F9 ARF1. (A) IFN-γ ELISPOT assay using spleen cells of B0702 mice immunized with the p18 ... Cellular immune response to cryptic epitopes during therapeutic gene transfer.. Li C1, Goudy K, Hirsch M, Asokan A, Fan Y, ... A CTL response to the F9 ARF epitopes after AAV2/F9 delivery. (A) Detection of CTL responses in B0702 mice injected with AAV2/ ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Seiber+D%5Bau%5D&dispmax=50