KEGG PATHWAY: Breast cancer - Homo sapiens (human)
... and human epidermal growth factor receptor-2 (HER2), include: hormone receptor positive and HER2 negative (luminal A subtype), ... In HER2 positive breast tumours, HER2 activates the PI3K/AKT and the RAS/RAF/MAPK pathways, and stimulate cell growth, survival ...
KEGG PATHWAY: ErbB signaling pathway - Homo sapiens (human)
Ligand binding to the four closely related members of this RTK family -epidermal growth factor receptor (EGFR, also known as ... The ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular ...