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*  Trypsinogen activation in acute and chronic pancreatitis: is it a prerequisite? | Gut
According to this paradigm the process culminates in prematurely active digestive enzymes 'digesting' the acinar cell and ... Inhibition of trypsinogen activation by inhibiting the activity of cathepsin B11 12 or by deleting the cathepsin B gene13 has ... It is to be noted that premature trypsinogen activation has only been observed during acute pancreatitis, and that no ... Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis ...
http://gut.bmj.com/content/60/10/1305
*  Differential regulation of Ca2+/calmodulin-dependent enzymes by plant calmodulin isoforms and free Ca2+ concentration |...
... for the activation of five CaM-dependent enzymes, and the Ca2+ dependence of their target enzyme activation. SCaM-1 activated ... but SCaM-4 produced no activation of this enzyme. Both CaM isoforms supported near maximal activation of CaM-dependent protein ... Importantly, SCaM isoforms showed a distinct Ca2+ concentration requirement for target enzyme activation. SCaM-4 required 4- ... fold higher [Ca2+] for half-maximal activation of CaM KII, and 1.5-fold higher [Ca2+] for activation of cyclic nucleotide ...
http://www.biochemj.org/content/350/1/299
*  Muscle remodeling in relation to blood supply: implications for seasonal changes in mitochondrial enzymes | Journal of...
... the rapidity of the response suggests a post-translational route of enzyme activation, rather than induced expression. It is ... Ventricular enzymes in relation to anemia and cold acclimation. The data for each enzyme is shown as both specific activity ( ... Muscle enzymes. We investigated the effects of phenylhydrazine treatment on enzymes in white muscle, red muscle and cardiac ... Muscle enzymes in relation to cold acclimation. Open bars (warm acclimated) represent the activities of muscle enzymes prior to ...
http://jeb.biologists.org/content/208/3/515
*  Oxidant Stress Enhances Adenylyl Cyclase Activation | Circulation Research
... and an enzyme-specific stimulator (forskolin/Mn2+) all showed comparable enhancement. This suggests that H2O2 exerts its effect ... The effect of H2O2 on adenylyl cyclase activation. The effect of pretreatment with H2O2 (100 μmol/L for 30 minutes) and the ... Both sensitization and desensitization of adenylyl cyclase activation have been reported with ischemia and reperfusion.36 37 38 ... Kawabe J, Iwami G, Ebina T, Ohno S, Katada T, Ueda Y, Homcy CJ, Ishikawa Y. Differential activation of adenylyl cyclase by ...
http://circres.ahajournals.org/content/77/4/710
*  Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host. | SBRC
Adenylate Cyclase, Animals, Catalytic Domain, Cell Line, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Enzyme Activation, ... Activation of these enzymes requires the dimerization of the catalytic domain and typically occurs under stress. Using a ... Specifically, activation of trypanosome adenylate cyclase resulting from parasite phagocytosis by liver myeloid cells inhibited ... the synthesis of the trypanosome-controlling cytokine tumor necrosis factor-α through activation of protein kinase A in these ...
http://sbrc.vub.ac.be/node/196
*  Enzyme Activation - MeSH - NCBI
Enzyme Activations. All MeSH CategoriesPhenomena and Processes CategoryChemical PhenomenaBiochemical PhenomenaEnzyme Activation ... Enzyme Activation. Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation ... conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. ... by ions (activators); 2, activation by cofactors (coenzymes); and 3, ...
https://www.ncbi.nlm.nih.gov/mesh?Db=mesh&Cmd=DetailsSearch&Term=%22Enzyme+Activation%22%5BMeSH+Terms%5D
*  Phosphoinositides in Subcellular Targeting and Enzyme Activation Stenmark Harald - ?????? OZON.ru ??? ??????? ??????? ...
Phosphoinositides in Subcellular Targeting and Enzyme Activation ?????? Stenmark Harald ... Phosphoinositides in Subcellular Targeting and Enzyme Activation ?????? ??? ??? ???? ?????? 3500 ...
http://www.ozon.ru/context/detail/id/3835883/
*  Discovery of enzyme activation process could lead to new heart attack treatments (w/ Video)
... January 10, 2010, Indiana ... 10 that the compound, called Alda-1, acts much like a shim to prop up a mutated form of a key enzyme, restoring the enzyme's ... The enzyme, called ALDH2, plays an important role in metabolizing alcohol and other toxins, including those created by a lack ... Hurley likens to a woodworking procedure in which Alda-1 attaches to the ALDH2 enzyme at a crucial spot and acts like a shim or ...
https://phys.org/news/2010-01-discovery-enzyme-heart-treatments-video.html
*  Latency of plasma membrane H-ATPase in vesicles isolated by aqueous phase partitioning : Increased substrate accessibility or...
Increased substrate accessibility or enzyme activation. Plant Physiology, 85(3), 693-698. DOI: 10.1104/pp.85.3.693 ... We propose that plasma membrane ATPase activation is due not solely to vesicle disruption and accessibility of ATP to the ...
https://www.rti.org/publication/latency-plasma-membrane-h-atpase-vesicles-isolated-aqueous-phase-partitioning-increased
*  Abstract 3103: Differences in the DDR enzymes activation kinetics between normal and cancer cells could be utilized to achieve...
UV radiation and enzyme inhibitors in a time and dose dependent manner and looked at the resulting enzyme activation rates of ... Elucidation of the enzyme activation kinetics in a time and dose dependent manner of the proteins governing cell fate decision ... Here we explored the kinetics of activation of these key enzymes, the rates of their product formation and the interplay ... Abstract 3103: Differences in the DDR enzymes activation kinetics between normal and cancer cells could be utilized to achieve ...
http://cancerres.aacrjournals.org/content/72/8_Supplement/3103
*  Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and...
Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and ... Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and ... Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and ... Persulfide formation on mitochondrial cysteine desulfurase: enzyme activation by a eukaryote-specific interacting protein and ...
http://www.biochemj.org/content/448/2/171
*  Enzyme Activation | ISHAR Online
It is well known that activation of telomerase in the most types of organism's cells is not enough for telomere length ... The lifespan extension effect of CR has been strongly associated with an increased level and activation of the silent ... One of the fractionated compounds showed potent inhibition against COX enzymes with no inhibition against 5-LOX. It was ... Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. ...
http://isharonline.org/tags/enzyme-activation
*  Enzymes and activation energy. - Biology-Online
Enzymes greatly decrease the activation energy in 2 distinct ways:. i. Lowering required energy: An enzyme's selective three ... Q: Enzymes greatly decrease the activation energy. Explain two of the way they do this and be specific in terms of chemical ... Enzymes and activation energy.. Discussion of all aspects of biological molecules, biochemical processes and laboratory ... From Wikipedia on Enzymes:. The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis. By ...
https://www.biology-online.org/biology-forum/viewtopic.php?p=111398
*  Stabilization and Activation of Enzymes for synthesis in Organic Media
This invention covers a new process that allows the stabilization and activation of sensi-tive catalysts (respectively enzymes ... Stabilization and Activation of Enzymes for synthesis in Organic Media. 03.08.2005 ...
http://www.innovations-report.com/html/reports/technology-offerings/report-98948.html
*  Spätzle-Processing Enzyme-independent Activation of the Toll Pathway in <i>Drosophila</i>...
Spätzle-Processing Enzyme-independent Activation of the Toll Pathway in Drosophila Innate Immunity. Miki Yamamoto-Hino1), ... Spätzle-processing enzyme (SPE) is the only enzyme identified to date that functions in converting Spätzle to an active form ... In the present study, Toll activation induced by immune challenge was almost suppressed in spätzle mutant larvae and adults, ...
https://www.jstage.jst.go.jp/article/csf/41/1/41_16002/_article
*  Biology-Online • View topic - Activation Energy and Enzyme Catalysis
Activation Energy and Enzyme Catalysis. Discussion of all aspects of biological molecules, biochemical processes and laboratory ... Activation Energy and Enzyme Catalysis. by roark » Sun Feb 25, 2007 9:58 am ... 4) How does (Gibbs) free energy of activation relate to activation energy and threshold energy? 5) From what I understand, by ... it seems like the enzyme is increasing rate without changing activation energy. 3) How does a potential energy profile relate ...
http://www.biology-online.org/biology-forum/post-75924.html
*  Kinetic and structural studies of aldehyde oxidoreductase from Desulfovibrio gigas reveal a dithiolene-based chemistry for...
... with dithionite plus sulfide in the presence of dioxygen produces hydrogen peroxide not associated with the enzyme activation. ... Mononuclear Mo-containing enzymes of the xanthine oxidase (XO) family catalyze the oxidative hydroxylation of aldehydes and ... The fact that DgAOR does not need a sulfido ligand for catalysis indicates that the process leading to the activation of ... In contrast to XO, which is activated by resulfuration of the Mo site, DgAOR activation/inactivation is governed by the ...
https://ri.conicet.gov.ar/handle/11336/494
*  Describe the relationships between membrane channel proteins, membrane enzyme proteins, direct activation, and indirect...
... direct activation, and indirect activation. Include G proteins' and find homework help for other Science questions at eNotes ... Enzymes are a type of protein, so membrane enzyme proteins are enzymes that are attached to a cellular membrane. They perform ... Enzymes are a type of protein, so membrane enzyme proteins are enzymes that are attached to a cellular membrane. They perform ... Describe the relationships between membrane channel proteins, membrane enzyme proteins, direct activation, and indirect ...
https://www.enotes.com/homework-help/describe-relationships-between-membrane-channel-360863
*  Antibodies can determine the activation state of an enzyme?? - Biology Forum | Biology-Online Dictionary, Blog & Forum
The statement is 'antibodies can be used to determine the activation state of an enzyme'. My opinion is that this is true. Well ... Antibodies can determine the activation state of an enzyme??. Discussion of all aspects of biological molecules, biochemical ... If signal is detected it means that the enzyme is active and if not it is inactive. But I am not sure for that.. Can anyone ... The primary antibody can be made to bind only to active site of enzyme and the secondary antibody will bind to the primary one ...
https://www.biology-online.org/biology-forum/viewtopic.php?t=8401
*  Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes | Science
... as an enzyme that induces NLRP1B degradation and activation. Our results provide a unified mechanism for NLRP1B activation by ... Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes ... Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes ... Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes ...
https://science.sciencemag.org/content/364/6435/eaau1330
*  Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma...
Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ...
http://molpharm.aspetjournals.org/content/16/2/449
*  Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1...
Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1 ... Primary human osteoblasts exposed to 100 μM Quercetin for 4 h were examined for expression of the anti-oxidative enzymes HO-1 ... Activation precedes resorption followed by reversal and formation. Osteoblasts in particular play a key role in this cycle. ... Figure 4: Quercetin protects primary human osteoblasts from CSM-induced damage via upregulation of anti-oxidative enzymes HO-1 ...
https://www.hindawi.com/journals/tswj/2011/471426/
*  Function of Enzymes: Substrate, Active Site & Activation Energy - Video & Lesson Transcript | Study.com
... we'll learn how enzymes function to lower the activation energy of a chemical reaction. Enzymes bind to their substrates to ... What your cells have to help overcome a problem of high activation energy are called enzymes. Enzymes are proteins that lower ... In summary, enzymes are proteins that lower the activation energy of a chemical reaction. Enzymes are not consumed or produced ... Video: Function of Enzymes: Substrate, Active Site & Activation Energy. In this lesson, we'll learn how enzymes function to ...
https://study.com/academy/lesson/function-of-enzymes-substrate-active-site-activation-energy.html
*  Sodium restriction potentiates the renoprotective effects of combined vitamin D receptor activation and angiotensin-converting...
... restriction potentiates the renoprotective effects of combined vitamin D receptor activation and angiotensin-converting enzyme ...
https://insights.ovid.com/pubmed?PMID=26311058