Highlights - Biocenter FinlandHighlights - Biocenter Finland

Human parechovirus type 3 is a picornavirus that can cause severe infections in humans, resulting in sepsis and central nervous ... The best studied anti-picornaviral drug pleconaril and its derivatives work well against enteroviruses, large group of ... BCK has developed methods for differentiation of human iPSC derived cells into a variety of CNS and muscle cells. The ... After patenting the discovery (WO 2014128254 A1), the finding was verified with human iPSC-derived models and licenced by the ...
more infohttp://www.biocenter.fi/biocenter-finland/highlights.html

Documentation Tip: Human Enterovirus D68Documentation Tip: Human Enterovirus D68

RN Enterovirus D68 (EV-D68)-one of many non-polio enteroviruses-was initially isolated in California in 1962, from four ... Documentation Tip: Human Enterovirus D68 was last modified: November 4th, 2014 by John Verhovshek ... Enterovirus D68 (EV-D68)-one of many non-polio enteroviruses-was initially isolated in California in 1962, from four children ... Pallansch, M.A & Roos,R.P. (2001). Enteroviruses: polioviruses, coxsakieviruses, echoviruses, band newer enteroviruses. In ...
more infohttps://www.aapc.com/blog/28353-documentation-tip-human-enterovirus-d68/

Frontiers | Cellular Receptors for Human Enterovirus Species A | MicrobiologyFrontiers | Cellular Receptors for Human Enterovirus Species A | Microbiology

Recently, two human transmembrane proteins, P-selectin glycoprotein ligand-1 (PSGL-1) and scavenger receptor class B, member 2 ... Among HEV-A, coxsackievirus A16 (CVA16) and enterovirus 71 (EV71) are the major causative agents of hand, foot, and mouth ... Among HEV-A, coxsackievirus A16 (CVA16) and enterovirus 71 (EV71) are the major causative agents of hand, foot, and mouth ... two human transmembrane proteins, P-selectin glycoprotein ligand-1 (PSGL-1) and scavenger receptor class B, member 2 (SCARB2), ...
more infohttps://www.frontiersin.org/articles/10.3389/fmicb.2012.00105/full

Molecular basis for the acid-initiated uncoating of human enterovirus D68 | PNASMolecular basis for the acid-initiated uncoating of human enterovirus D68 | PNAS

2007) Enterovirus 94, a proposed new serotype in human enterovirus species D. J Gen Virol 88:849-858. ... 2002) Human rhinovirus 87 and enterovirus 68 represent a unique serotype with rhinovirus and enterovirus features. J Clin ... Molecular basis for the acid-initiated uncoating of human enterovirus D68. Yue Liu, Ju Sheng, Arno L. W. van Vliet, Geeta Buda ... Molecular basis for the acid-initiated uncoating of human enterovirus D68. Yue Liu, Ju Sheng, Arno L. W. van Vliet, Geeta Buda ...
more infohttps://www.pnas.org/content/115/52/E12209

Human enterovirus virion complex - Stock Image C035/5844 - Science Photo LibraryHuman enterovirus virion complex - Stock Image C035/5844 - Science Photo Library

Computer model showing the human enterovirus 71 mature virion capsid glycoprotein VP1 (red) complexed with Fab fragments of the ... Caption: Human enterovirus 71 complexed with antibody D5. Computer model showing the human enterovirus 71 mature virion capsid ... enterovirus, ev71, fab, glycoprotein, human, illustration, molecular model, molecular structure, molecule, monoclonal, nobody, ...
more infohttp://www.sciencephoto.com/media/847242/view

Clusters of Acute Respiratory Illness Associated with Human Enterovirus 68 --- Asia, Europe, and United States, 2008--2010Clusters of Acute Respiratory Illness Associated with Human Enterovirus 68 --- Asia, Europe, and United States, 2008--2010

Human enterovirus 68 (HEV68) is a unique enterovirus that shares epidemiologic and biologic features with human rhinoviruses. ... Enteroviruses and HRV are common, closely related human pathogens in the Picornaviridae family. Most enterovirus infections are ... "human rhinovirus/enterovirus"). Classic enteroviruses have prominent summer-fall seasonality in temperate climates (7,8), and ... Occurrence of human enterovirus 68, by month, duration, and geographic location --- Asia, Europe, and United States, 2008--2010 ...
more infohttps://www.cdc.gov/mmwr/preview/mmwrhtml/mm6038a1.htm

enterovirus d human Protocols and Video...'enterovirus d human' Protocols and Video...

Enterovirus D, Human: A species of Enterovirus infecting humans and consisting of 2 serotypes: Human enterovirus 68 and Human ...
more infohttps://www.jove.com/keyword/enterovirus+d+human

enterovirus c human Protocols and Video...'enterovirus c human' Protocols and Video...

Enterovirus C, Human: A species of Enterovirus infecting humans and containing 11 serotypes, all coxsackieviruses. ...
more infohttps://www.jove.com/keyword/enterovirus+c+human

Efficacy of Inactivation of Human Enteroviruses by Multiple-Wavelength UV LEDs | Science Inventory | US EPAEfficacy of Inactivation of Human Enteroviruses by Multiple-Wavelength UV LEDs | Science Inventory | US EPA

RNA enteroviruses. Of 12 enterovirus species, serotype representatives of the four human enteric species (enterovirus A-D) such ... Efficacy of Inactivation of Human Enteroviruses by Multiple-Wavelength UV LEDs. Contact. National Risk Management Research ... Presenting the efficacy of inactivation of four human enteroviruses by multiple-wavelength UV LEDs in American Society for ... Efficacy of Inactivation of Human Enteroviruses by Multiple-Wavelength UV LEDs. Presented at American Society of Microbiology ...
more infohttps://cfpub.epa.gov/si/si_public_record_report.cfm?Lab=NRMRL&direntryid=319575&subject=homeland%20security%20research&view=desc&sortby=pubdateyear&showcriteria=1&count=25&searchall=%27analytical%20methods%27%20or%20%27analytical%20method%27%20or%20%27method%20development%27%20or%20%27methods%20development%27%20or%20%27standardized%20analytical%20methods%27%20or%20%27sam%27%20or%20%22selected%20analytical%20methods%27

Pathologic Characterization of a Murine Model of Human Enterovirus 71 EncephalomyelitisPathologic Characterization of a Murine Model of Human Enterovirus 71 Encephalomyelitis

We describe a model of Enterovirus 71 encephalomyelitis in 2-week-old mice that shares many features with the human central ... Mice were infected via oral and parenteral routes with a murine-adapted virus strain originally from a fatal human case. The ...
more infohttps://insights.ovid.com/jnexn/200806000/00005072-200806000-00002

Welcome to CDC stacks | Human Enterovirus Genotype C104, China - 18999 | Emerging Infectious DiseasesWelcome to CDC stacks | Human Enterovirus Genotype C104, China - 18999 | Emerging Infectious Diseases

Enterovirus Enterovirus Infections EV-C104 Female Genotype Human Enterovirus Humans Infant Infant, Newborn Letter Letters To ... We assessed neurologic sequelae associated with an enterovirus 71 (EV71) outbreak in South Korea during 2009. Four of 94 ...
more infohttps://stacks.cdc.gov/view/cdc/18999

Development of a transcription-reverse transcription concerted reaction method for specific detection of human enterovirus 71...Development of a transcription-reverse transcription concerted reaction method for specific detection of human enterovirus 71...

Development of a transcription-reverse transcription concerted reaction method for specific detection of human enterovirus 71 ... Development of a Transcription-Reverse Transcription Concerted Reaction Method for Specific Detection of Human Enterovirus 71 ... Development of a Transcription-Reverse Transcription Concerted Reaction Method for Specific Detection of Human Enterovirus 71 ... Development of a Transcription-Reverse Transcription Concerted Reaction Method for Specific Detection of Human Enterovirus 71 ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/22357494

Frequency and Dynamics of Recombination within Different Species of Human Enteroviruses | Journal of VirologyFrequency and Dynamics of Recombination within Different Species of Human Enteroviruses | Journal of Virology

... a range of different enterovirus serotypes circulate in human populations. The evolution of enteroviruses occurs through ... Enteroviruses are members of the family Picornaviridae that cause widespread infections in human and other mammalian ... Frequency and Dynamics of Recombination within Different Species of Human Enteroviruses. Peter Simmonds, Jon Welch ... In future work, it will be of value to carry out more structured sampling of enterovirus variants in human populations over ...
more infohttps://jvi.asm.org/content/80/1/483.full

ASMscience | Human Enterovirus InfectASMscience | Human Enterovirus Infect

Enteroviruses have also been implicated in the etiology of chronic diseases such as inflammatory myositis, diabetes mellitus, ... The enteroviruses are leading causes of meningitis, encephalitis, poliomyelitis, myocarditis, and nonspecific febrile illnesses ... The enteroviruses cause between 10 and 15 million symptomatic infections in the U.S. each year, ranging in severity from the ... Home / Books / Human Enterovirus Infections Human Enterovirus Infections. Editor: Harley A. Rotbart1 VIEW AFFILIATIONS HIDE ...
more infohttp://www.asmscience.org/content/book/10.1128/9781555818326

Human Enterovirus RNA in Monthly Fecal Samples and Islet Autoimmunity in Norwegian Children With High Genetic Risk for Type 1...Human Enterovirus RNA in Monthly Fecal Samples and Islet Autoimmunity in Norwegian Children With High Genetic Risk for Type 1...

High prevalence of human enterovirus a infections in natural circulation of human enteroviruses. J Clin Microbiol 2006;44:4095- ... Frequency of human enterovirus before development of autoimmunity. The frequency of human enterovirus RNA in stool samples ... Testing for human enterovirus RNA was performed in duplicate in 20-μl-volume one-step real-time RT-PCR with a primer-probe ... Quantity of human enterovirus RNA. The effect of viral load was assessed by dividing the positivity into two categories: low to ...
more infohttp://care.diabetesjournals.org/content/34/1/151

Figure 1 - Accuracy of Diagnostic Methods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999-2011 - Volume...Figure 1 - Accuracy of Diagnostic Methods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999-2011 - Volume...

Of 14,657 patients whose samples were tested, 4,762 (32.5%) samples were positive for human enterovirus (human EV); as ... There are currently no treatments specific to human EV infections; surveillance of enterovirus infections such as this study ... Genotypes enterovirus 71, echovirus 30, coxsackievirus B5, enterovirus 6, and coxsackievirus B2 were the most common genotypes ... Accurate test results correlated clinical syndromes to enterovirus genotypes: aseptic meningitis to echovirus 30, enterovirus 6 ...
more infohttps://wwwnc.cdc.gov/eid/article/19/8/13-0496-f1

IJMS | Free Full-Text | Chebulagic Acid, a Hydrolyzable Tannin, Exhibited Antiviral Activity in Vitro and in Vivo against Human...IJMS | Free Full-Text | Chebulagic Acid, a Hydrolyzable Tannin, Exhibited Antiviral Activity in Vitro and in Vivo against Human...

The utilization of the chebulagic acid treatment on mice challenged with a lethal dose of enterovirus 71 was able to ... Chebulagic acid may represent a potential therapeutic agent to control infections to enterovirus 71. ... Human enterovirus 71 is one of the major causative agents of hand, foot and mouth disease in children under six years of age. ... Human enterovirus 71 is one of the major causative agents of hand, foot and mouth disease in children under six years of age. ...
more infohttp://mdpi.com/1422-0067/14/5/9618/xml

Real-time RT-PCR Assay for Rapid, Highly Sensitive and Specific Detection of Human Enterovirus D68 (EV-D68) | Office of...Real-time RT-PCR Assay for Rapid, Highly Sensitive and Specific Detection of Human Enterovirus D68 (EV-D68) | Office of...

Human Enterovirus D68 (EV-D68) is a non-polio enterovirus that can cause mild to severe respiratory illness, especially in ... Real-time RT-PCR Assay for Rapid, Highly Sensitive and Specific Detection of Human Enterovirus D68 (EV-D68) ... Quality control/quality assurance testing for Enterovirus isolates. *Detection of currently circulating, newly evolved human EV ... Sensitive and Specific Detection of Human Enterovirus D68 (EV-D68). For collaboration opportunities, please contact CDC TTO at ...
more infohttps://www.ott.nih.gov/technology/e-011-2015-0

Welcome to CDC stacks | Recombinant Human Enterovirus 71 - 14595 | Emerging Infectious DiseasesWelcome to CDC stacks | Recombinant Human Enterovirus 71 - 14595 | Emerging Infectious Diseases

Enterovirus Enterovirus 71 Enterovirus Infections Foot And Mouth Disease Genome, Viral Hand Hand, Foot And Mouth Disease Humans ... Human enterovirus 71 (EV-71) is the main etiologic agent of hand, foot and mouth disease (HFMD). We sought to identify EV-71 ... Complex recombinant forms of CA16-related viruses involving multiple human enteroviruses, sub... ... Multirecombinant Enterovirus A71 Subgenogroup C1 Isolates Associated with Neurologic Disease, France, 2016-2017 ...
more infohttps://stacks.cdc.gov/view/cdc/14595

Microbiology Society Journals | Enteroviruses 76, 89, 90 and 91 represent a novel group within the species Human enterovirus AMicrobiology Society Journals | Enteroviruses 76, 89, 90 and 91 represent a novel group within the species Human enterovirus A

... these data support their identification as four new types within the species Human enterovirus A (HEV-A). In almost all cases, ... Partial 3D sequences were more closely related to those of simian EVs than to human viruses in HEV-A. These results suggest ... the VP1 sequences were more similar to those of some simian EVs than to the human EVs. Partial 3D sequences of all 19 isolates ... identical to the homologous sequences of the recognized human EV serotypes, but within each group the sequences are more than ...
more infohttp://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.80475-0

Human enterovirus 71 subgenotype B3 lacks coxsackievirus A16-like neurovirulence in mice infection | Virology Journal | Full...Human enterovirus 71 subgenotype B3 lacks coxsackievirus A16-like neurovirulence in mice infection | Virology Journal | Full...

Analysis of human enterovirus 71 (EV-71) subgenotype B3 genome sequences revealed that the 3D RNA polymerase and domain Z of ... Analysis of human enterovirus 71 (EV-71) subgenotype B3 genome sequences revealed that the 3D RNA polymerase and domain Z of ... Chan YF, AbuBakar S: Recombinant human enterovirus 71 in hand, foot and mouth disease patients. Emerg Infect Dis 2004, 10: 1468 ... Cardosa MJ, Perera D, Brown BA, Cheon D, Chan HM, Chan KP, Cho H, McMinn P: Molecular epidemiology of human enterovirus 71 ...
more infohttps://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-74

Incorrect identification of recent Asian strains of Coxsackievirus A16 as human enterovirus 71: Improved primers for the...Incorrect identification of recent Asian strains of Coxsackievirus A16 as human enterovirus 71: Improved primers for the...

Serotype identification of human enteroviruses. Human enterovirus serotype identification was achieved using 2 approaches. In ... All 39 human enterovirus 71 isolates were positive and none of the 38 Coxsackievirus A16, 127 other enteroviruses and 14 ... Human enterovirus 71 has emerged as an important pathogen in the Asia Pacific region and it is important to be able to make a ... Our new primers will be useful in rapid diagnosis of human enterovirus 71 infection, and can also be used as a screening tool ...
more infohttps://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-4-11

Human enteroviruses are not the cause of neurological impairments in children at the Korle-Bu Teaching HospitalHuman enteroviruses are not the cause of neurological impairments in children at the Korle-Bu Teaching Hospital

CONCLUSION: Non-polio enteroviruses and chikugunya virus were found not to be the etiologic agent responsible for the ... Studies from the Asia Pacific region suggest a link with non-polio enteroviruses. The aim of the study was to investigate the ... RESULTS: Enterovirus isolation rate was approximately 0.67 %. Intratypic differentiation by molecular characterization ... association between non-polio enterovirus and acute encephalopathy causing neurological morbidity in children. METHODS: One ...
more infohttp://www.panafrican-med-journal.com/content/article/18/232/full/

Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection | DiabetesCytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection | Diabetes

Enteroviruses of the human enterovirus B species (HEV-Bs) (e.g., coxsackie B viruses [CVBs] and echoviruses) have been ... Enteroviruses, particularly human enterovirus B species (HEV-Bs), such as coxsackie B viruses (CVBs) and echoviruses (EVs), are ... Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro. J Med Virol 2011;83:658-664pmid: ... Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection. Barbara M. Schulte, Kjerstin H.W. ...
more infohttp://diabetes.diabetesjournals.org/content/61/8/2030