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*  2018 February 05 | Atlas of Science
... depends on the expression of various growth factors but Vascular Endothelial Growth factor (VEGF) ranks as the key inducer and ... Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli ... Angiogenesis, the growth of blood vessel from the existing vasculature, ...
http://atlasofscience.org/2018/02/05/
*  Updates on the pathophysiology of systemic sclerosis | Atlas of Science
Vascular Endothelial Growth Factor; NO: Nitric Oxide; NOS-2: inducible NO synthase; NOS-3: endothelial NO synthase; ET-1: ... Connective Tissue Growth Factor; PDGF: Platelet-Derived Growth Factor; FGF: Fibroblast Growth Factor; ET-1: Endothelin-1; IL-1 ... Transforming Growth Factor-Beta; PDGF: Platelet-Derived Growth Factor; CTGF: Connective Tissue Growth Factor. ... Early endothelial dysfunction appears to be the triggering factor, with endothelial activation induced by anti-endothelial ...
http://atlasofscience.org/updates-on-the-pathophysiology-of-systemic-sclerosis/
*  Vistafin and endothelial progenitor cell dysfunction in diabetes mellitus | Atlas of Science
CD34+ antigen and VEGFR-2+ vascular growth ligands (Vascular Endothelial Growth Factor Rreceptor-2), CD133+, as well as CD14+, ... EPCs are mobilized from bone marrow and probably from peripheral tissues upon injury in result in growth factors and ... Endothelial progenitor cells (EPCs) is a heterogenic population of mononuclear cells expressing endothelial and progenitor ... Vistafin and endothelial progenitor cell dysfunction in diabetes mellitus. The prevalence of type 2 diabetes mellitus (T2DM) ...
http://atlasofscience.org/vistafin-and-endothelial-progenitor-cell-dysfunction-in-diabetes-mellitus/
*  Towards better tissue regeneration: Improved vessel growth using synthetic polymers | Atlas of Science
... endothelial cells in red, nuclei in cyan); c) Scheme of synergistic effect of integrin/growth factor receptor stimulation. ... A new role for a well-known hematopoietic factor… Multiple growth factors produced in our organism by different types of cells ... and vascular endothelial growth factor (VEGF) (Fig. 1a). Physiologically, fibronectin facilitates a crosstalk between cells and ... Two types of binding sites important for our system are integrin binding domains where cells can attach, and growth factor (GF ...
http://atlasofscience.org/towards-better-tissue-regeneration-improved-vessel-growth-using-synthetic-polymers/
*  Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli...
... depends on the expression of various growth factors but Vascular Endothelial Growth factor (VEGF) ranks as the key inducer and ... the growth of blood vessel from the existing vasculature, ... various growth factors but Vascular Endothelial Growth factor ( ... Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli ... Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli ...
http://atlasofscience.org/expression-purification-and-functionality-of-bioactive-recombinant-human-vascular-endothelial-growth-factor-vegf165-in-e-coli/
*  Go with the flow: Studying the movement of T-cells to sites of inflammation | Atlas of Science
... muscle that has been stimulated with a cytokine called Transforming Growth Factor-β1 (TGF-β1) (Images courtesy of M. Chimen, ... Endothelial cells report changes in their local environment. In healthy tissues, they exist in a resting state, "invisible" to ... adhesion, adipokines, adiponectin, cell culture, cytokines, endothelial cells, flow, inflammation, intravital, leukocyte, ... Finally, the arrested T-cell crosses the vessel wall through the endothelial junctions, and continues to move through the ...
http://atlasofscience.org/go-with-the-flow-studying-the-movement-of-t-cells-to-sites-of-inflammation/
*  Interleukin-18: Critical molecule in promoting allergic diseases | Atlas of Science
Cytokine Growth Factor Rev. 2016 Dec. Involvement of interleukin-18 in the pathogenesis of human eosinophilic esophagitis.. ... L-arginine and B vitamins improve endothelial function in subjects with mild to moderate blood pressure elevation ... Bone marrow from naive mice cultured with stem cell factor (SCF) and IL-18 differentiate these inflammatory cells, which are ... Zinc supplementation and allergy Zinc is an essential trace element and an important factor of approximately 300 human enzymes ...
http://atlasofscience.org/interleukin-18-critical-molecule-in-promoting-allergic-diseases/
*  Insights into the molecular basis of posterior polymorphous corneal dystrophy | Atlas of Science
Human corneal endothelial cells do not normally divide after birth. It is well established that abnormal proliferation due to ... Mesenchymal-to-epithelial transition (MET) is mediated by a precise regulation of transcription factors ZEB1, OVOL2 and GRHL2. ... Neurodevelopmental syndromes refer to a group of inborn diseases that present with impairments of the growth and development of ... In PPCD, reduced expression of ZEB1 and ectopic expression of GRHL2 or OVOL2 in corneal endothelial cells result in cell state ...
https://atlasofscience.org/insights-into-the-molecular-basis-of-posterior-polymorphous-corneal-dystrophy/
*  An introduction to modelling lymphocyte migration in vitro | Atlas of Science
Lymphocyte recruitment to inflamed endothelial cells (EC) is fundamental to immune homeostasis - providing both cell-mediated ... Keeping a clean house to suppress HER2+ breast tumor growth * The nature of bel-1 attC stabilizes its genetic environment and ... adhesion, adipokines, adiponectin, cell culture, cytokines, endothelial cells, flow, inflammation, leptin, lymphocyte, ... EC monolayers can then be treated with inflammatory cytokines such as Tumour necrosis factor-α (TNF-α) and Interferon-γ (IFN-γ ...
http://atlasofscience.org/an-introduction-to-modelling-lymphocyte-migration-in-vitro/