EEF2K (eukaryotic elongation factor 2 kinase)  EEF2K (eukaryotic elongation factor 2 kinase)
... eukaryotic elongation factor 2 kinase), Authors: Bulent Ozpolat, Ozgur Ozkayar. Published in: Atlas Genet Cytogenet Oncol ... response to ischemia protein kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP ... response to ischemia protein kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP ... Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its ...
more infohttp://atlasgeneticsoncology.org/Genes/GC_EEF2K.html
Elongation factor 2 kinase - Wikipedia  Elongation factor 2 kinase - Wikipedia
Other names in common use include Ca/CaM-kinase III, calmodulin-dependent protein kinase III, CaM kinase III, eEF2 kinase, eEF- ... protein-serine/threonine kinases). The systematic name of this enzyme class is "ATP:[elongation factor 2] phosphotransferase". ... "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its ... In enzymology, an elongation factor 2 kinase (EC 2.7.11.20) is an enzyme that catalyzes the chemical reaction: ATP + [ ...
more infohttps://en.wikipedia.org/wiki/Elongation_factor_2_kinase
Eef2k - Eukaryotic elongation factor 2 kinase - Rattus norvegicus (Rat) - Eef2k gene & protein  Eef2k - Eukaryotic elongation factor 2 kinase - Rattus norvegicus (Rat) - Eef2k gene & protein
Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single ... Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. ... Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single ... Eukaryotic elongation factor 2 kinaseAdd BLAST. 723. Amino acid modifications. Feature key. Position(s). DescriptionActions. ...
more infohttp://www.uniprot.org/uniprot/P70531
Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin.  - PubMed - NCBI  Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin. - PubMed - NCBI
Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin.. Lee K1, Alphonse S2, Piserchio A2 ... Binding of Ca(2+)-loaded calmodulin (CaM) activates eukaryotic elongation factor 2 kinase (eEF-2K) that phosphorylates eEF-2, ... Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin ... Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/?term=PMC5014583
Immune Reactions Against Elongation Factor 2 Kinase: Specific Pathogenesis of Gastric Ulcer from Helicobacter pylori Infection  Immune Reactions Against Elongation Factor 2 Kinase: Specific Pathogenesis of Gastric Ulcer from Helicobacter pylori Infection
N. T. Redpath and C. G. Proud, "Cyclic AMP-dependent protein kinase phosphorylates rabbit reticulocyte elongation factor-2 ... "Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase," Proceedings of the ... In prokaryote including H.pylori, elongation factor G (EF-G) is the counterpart of EF-2 in eukaryotic cells. And EF-G is also ... We report here that elongation factor 2 kinase (EF-2K) could be a candidate for the epitopic protein of antibodies in gastric ...
more infohttps://www.hindawi.com/journals/jir/2009/850623/
Oxidized LDL-Mediated Macrophage Survival Involves Elongation Factor-2 Kinase | Arteriosclerosis, Thrombosis, and Vascular...  Oxidized LDL-Mediated Macrophage Survival Involves Elongation Factor-2 Kinase | Arteriosclerosis, Thrombosis, and Vascular...
Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human ... Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its ... p38 MAP kinase, a negative regulator of eEF2 kinase, is activated on growth factor withdrawal, a response that can be inhibited ... Second, growth factor withdrawal can markedly reduce the activity of eEF2 kinase. Wu et al reported that eEF2 kinase promotes ...
more infohttp://atvb.ahajournals.org/content/29/1/92
Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes | Biochemical Journal  Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes | Biochemical Journal
Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes. Tricia A. DIGGLE, Nicholas T. REDPATH, Kate J ... Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes ... Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes ... Regulation of protein-synthesis elongation-factor-2 kinase by cAMP in adipocytes ...
more infohttp://www.biochemj.org/content/336/3/525
Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen...  Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen...
Eukaryotic elongation factor 2 kinase (eEF2K) is a Ca(2+)/calmodulin-dependent protein kinase. We previously revealed that ... Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen ... A-484954 inhibited MCT-induced NADPH oxidase-1 expression and ROS generation as well as matrix metalloproteinase-2 activation. ... PAH via stimulation of vascular structural remodeling perhaps through NADPH oxidase-1/ROS/matrix metalloproteinase-2 pathway. ...
more infohttps://www.sigmaaldrich.com/catalog/papers/25770246
Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor...  Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor...
We have previously reported that eukaryotic elongation factor-2 kinase (eEF-2 kinase, also known as Ca(2+)/calmodulin-dependent ... Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor ... Cytoprotective Effect of the Elongation Factor-2 Kinase-Mediated Autophagy in Breast Cancer Cells Subjected to Growth Factor ... Cytoprotective Effect of the Elongation Factor-2 Kinase-Mediated Autophagy in Breast Cancer Cells Subjected to Growth Factor ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/20300520?dopt=Abstract
Eukaryotic elongation factor 2 kinase  Eukaryotic elongation factor 2 kinase
This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and ... Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single ... Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. ... The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by ...
more infohttps://pharos.nih.gov/idg/targets/EEF2K
Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in...  Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in...
Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain. , Neuroscience letters , 9/13/2002 ... calmodulin-dependent protein kinase that is highly specific for eukaryotic elongation factor-2. In the present study, we ... Sakagami H, Nishimura H, Saito R, Kondo H. Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent ... Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in ...
more infohttps://www.docphin.com/research/article-detail/8821366/PubMedID-12213630/Transient-up-regulation-of-elongation-factor-2-kinase-Ca2-calmodulin-dependent-protein-kinase-III-messenger-RNA-in-developing-mouse-brain
Nutrients | Free Full-Text | Post-Meal Responses of Elongation Factor 2 (eEF2) and Adenosine Monophosphate-Activated Protein...  Nutrients | Free Full-Text | Post-Meal Responses of Elongation Factor 2 (eEF2) and Adenosine Monophosphate-Activated Protein...
... energy status by preventing increases in AMP/ATP and phosphorylation of adenosine monophosphate-activated protein kinase (AMPK ... that the duration of the meal response is limited by energy status of the cell and inhibition of translation elongation factor ... In summary, the incongruity between MPS and translation initiation at 180 min reflects a block in translation elongation due to ... Consistent with MPS findings, the supplements maintained elongation activity and cellular ...
more infohttp://mdpi.com/2072-6643/4/11/1723
EEF2K (mouse)  EEF2K (mouse)
Eukaryotic elongation factor 2 kinase Show on y-axis - References (HTP + LTP). References (LTP). References (HTP). ...
more infohttps://www.phosphosite.org/proteinAction.action?id=1536&showAllSites=true
Browse ORF cDNA clones by species Homo sapiens, letter l, page 1  Browse ORF cDNA clones by species Homo sapiens, letter l, page 1
eukaryotic elongation factor 2 kinase. protein-coding. LOC105373289. collagen alpha-1(III) chain-like. protein-coding. ... 0 1 2 3 4 5 6 7 8 9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ... ligand dependent nuclear receptor interacting factor 1. protein-coding. LRIT3. leucine rich repeat, Ig-like and transmembrane ... formin-2-like. protein-coding. LOC101059949. putative ankyrin repeat domain-containing protein 20A12 pseudogene. protein-coding ...
more infohttps://www.genscript.com/gene/9606/homo-sapiens?search=l
EEF2K - PCR Primer Pair - Probe | PrimePCR | Bio-Rad  EEF2K - PCR Primer Pair - Probe | PrimePCR | Bio-Rad
This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and ... The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by ... This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell ...
more infohttp://www.bio-rad.com/en-us/prime-pcr-assays/assay/qhsacip0031018-primepcr-probe-assay-eef2k-human
Phospho anti-EEF2 (T56 + T58) antibody [EP833Y] (ab82981) | Abcam  Phospho anti-EEF2 (T56 + T58) antibody [EP833Y] (ab82981) | Abcam
The molecular mechanism of eukaryotic elongation factor 2 kinase activation.. J Biol Chem 289:23901-16 (2014). Human . Read ... Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. ... Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes ... Lane 2 : Serum starved 293 cell lysate. Lysates/proteins at 10 µg per lane.. Secondary. All lanes : HRP labelled goat anti- ...
more infohttp://www.abcam.com/eef2-phospho-t56-t58-antibody-ep833y-ab82981.html
Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men ...  Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men ...
... protein kinase B (AKT) Ser473, eukaryotic elongation factor 2 (eEF2) Thr56, eukaryotic initiation factor 2α (eIF2α) Ser51, ... AMP-activated protein kinase (AMPK) Thr173 (D), protein kinase B (Akt) Ser473 (E), eukaryotic initiation factor 2α (eIF2α) ... 2015) Regulation and roles of elongation factor 2 kinase. Biochem. Soc. Trans. 43 (3), doi:doi:10.1042/BST20140323. ... 2017) Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase. Cell. Signal. 36 ...
more infohttp://www.clinsci.org/content/131/21/2643
Understanding Autophagy to Enhance Clinical Discovery | The New York Academy of Sciences  Understanding Autophagy to Enhance Clinical Discovery | The New York Academy of Sciences
... by EF2 kinase stops protein elongation and saves the cell's energy, and many types of tumors have elevated levels of EF2 kinase ... Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy. Cell Signal. 2016 ... "Really the only mechanism to do that is to control the activity of elongation factor 2," said Versele.. Phosphorylation of ... However, his team found that the protein elongation factor EF2 interacts with autophagy mediator Beclin-1. That led the ...
more infohttps://www.nyas.org/ebriefings/understanding-autophagy-to-enhance-clinical-discovery/
Red wine affects vision  | NHS Choices | Nursing Times  Red wine affects vision | NHS Choices | Nursing Times
Resveratrol Regulates Pathologic Angiogenesis by a Eukaryotic Elongation Factor-2 Kinase-Regulated Pathway.American Journal of ... eukaryotic elongation factor-2 kinase'. This contradicted previous research indicating that resveratrol interacts with proteins ... 2 August 2018Steve Ford. People who either abstain from drinking from alcohol in the long term or drink heavily are at ... Metformin - the cheap drug routinely used for the treatment of type 2 diabetes - could also help millions of other patients ...
more infohttps://www.nursingtimes.net/news/behind-the-headlines-archive/-red-wine-affects-vision/5016622.article
Toward Multiscale Modeling of Molecular and Biochemical Events Occurring at Fertilization Time in Sea Urchins | Springer for...  Toward Multiscale Modeling of Molecular and Biochemical Events Occurring at Fertilization Time in Sea Urchins | Springer for...
Proud CG (2015) Regulation and roles of elongation factor 2 kinase. Biochem Soc Trans 43:328-332. https://doi.org/10.1042/ ... Malumbres M (2014) Cyclin-dependent kinases. Genome Biol 15:122CrossRefPubMedPubMedCentralGoogle Scholar ... Gingras AC, Raught B, Sonenberg N (1999) eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of ... Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. ...
more infohttps://rd.springer.com/chapter/10.1007%2F978-3-319-92486-1_5