Open Access Journals
Mar Drugs 8: 1962-1987. * 113. Qin C, Zhou B, Zeng L, et al. (2004) The physicochemical properties and antitumor activity of ... Batthacharya AS, Batthacharya A, Pletschke BI (2015) Synergism of fungal and bacterial cellulases and hemicellulases: a novel ... Mar Drugs 13: 1925-1965. * 43. Kinet R, Destain J, Hiligsmann S, et al. (2015) Thermophilic and cellulolytic consortium ... 2014) Klebsiella pneumoniae yfiRNB operon affects biofilm formation, polysaccharide production and drug susceptibility. ...http://www.aimspress.com/article/10.3934/bioeng.2015.3.163
Drug Synergism | ISHAR Online
The MRSA test strains were found to be multi-drug resistant and also exhibited high level of resistance to common beta-lactam ...http://isharonline.org/tags/drug-synergism
Laser Synergism with Drug Eluting Balloon for Treatment of In-Stent Restenosis in the Lower Extremities | SpringerLink
Laser Synergism with Drug Eluting Balloon for Treatment of In-Stent Restenosis in the Lower Extremities. ... van den Berg J.C. (2015) Laser Synergism with Drug Eluting Balloon for Treatment of In-Stent Restenosis in the Lower ... Drug eluting balloons. Tech Vasc Interv Radiol. 2010;13(1):59-63.CrossRefPubMedGoogle Scholar ... Drug-eluting balloon: very short-term exposure and overlapping. Thromb Haemost. 2009;101(1):201-6.PubMedGoogle Scholar ...https://link.springer.com/chapter/10.1007/978-1-4471-5220-0_13
Frontiers | Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on...
Drug Synergism Evaluation. To determine potential synergistic drug effects on growth of CSCs GBM1, GBM2, and GBM3, cells were ... As compared to single drug treatments, the drug combination increased the percentage of apoptotic cells (GBM2: 41.27% of early+ ... Anticancer Drug Discov. 10, 145-162. doi: 10.2174/1574892810666150317144511. PubMed Abstract , CrossRef Full Text , Google ... Isobolograms of drug combination on GBM1, GBM2, and GBM3 CSC viability after treatment for 48 and 72 h, are represented. ...https://www.frontiersin.org/articles/10.3389/fnmol.2016.00107/full
Itraconazole targets cell cycle heterogeneity in colorectal cancer | JEM
Drug synergism assay and analysis. HT55 and SW948 cells were seeded at concentration of 105 cells per ml in a 96-well plate. ... A) Schematic of the drug screen protocol using YFP-1322 mice. (B) Column graphs of the effect of candidate drugs on organoid ... Drug screen compounds and other reagents. HGF (R&D), Dkk1 (R&D), Wif1 (R&D), Draxin (R&D), sFRP1 (R&D), sFRP5 (R&D), BMP4 (R&D ... From the drug screen, as a result of the limited numbers of cells present in wells treated with high dose (2.5 µM) itraconazole ...http://jem.rupress.org/content/215/7/1891
Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS - Full Text View ...
Drug Evaluation. Acquired Immunodeficiency Syndrome. Cachexia. Drug Synergism. Additional relevant MeSH terms: ...https://clinicaltrials.gov/show/NCT00000646?order=69
Needs monitoring with quetiapine : Chinese Medical Journal
Drug synergism: An interaction between 2 or more drugs that causes the total effect of the drugs to be greater than the sum of ... Evidence of Drug synergism happened in this case. *The improvement seen is due to the removal of one of the drugs causing ... 7. Drug synergism. Retrieved from https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/760/drug-synergism on 04/08/2018.. * ... Here, in this case, drug synergism has happened since the patient developed remarkable signs and symptoms of acute pancreatitis ...https://journals.lww.com/cmj/Fulltext/2019/01050/Needs_monitoring_with_quetiapine.20.aspx
Interleukin-2 and a T cell hybridoma (MP6) derived B cell-stimulatory factor act synergistically to induce proliferation and...
Cell Division / drug effects. DNA / biosynthesis*. Dose-Response Relationship, Drug. Drug Synergism. Humans. Interleukin-2 / ... Cell Cycle / drug effects. Cell Differentiation / drug effects. ... and act in strong synergism with induction of simultaneous high ...http://www.biomedsearch.com/nih/Interleukin-2-T-cell-hybridoma/2787454.html
Gene profiling of normal human bronchial epithelial cells in response to asbestos and benzo(a)pyrene diol epoxide (BPDE).
Drug Synergism. Epithelial Cells / drug effects*, metabolism. Gene Expression / drug effects*. Gene Expression Profiling*. ... Bronchi / cytology, drug effects*, metabolism. Cells, Cultured. Down-Regulation. ...http://www.biomedsearch.com/nih/Gene-profiling-normal-human-bronchial/18197826.html
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Synergism of Curcumin and Cytarabine in the Down Regulation of Multi-Drug Resistance Genes in Acute Myeloid Leukemia |...
Synergism of Curcumin and Cytarabine in the Down Regulation of Multi-Drug Resistance Genes in Acute Myeloid Leukemia. Author(s ... Title:Synergism of Curcumin and Cytarabine in the Down Regulation of Multi-Drug Resistance Genes in Acute Myeloid Leukemia ... "Synergism of Curcumin and Cytarabine in the Down Regulation of Multi-Drug Resistance Genes in Acute Myeloid Leukemia", Anti- ... Letters in Drug Design & Discovery. *Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy. Anti-Cancer Agents in ...http://www.eurekaselect.com/134025/article
Synergistic Antinociceptive Effects of Ketamine and Morphine in the Orofacial Capsaicin Test in the Rat | Anesthesiology | ASA...
To identify drug synergism in the drug combination, the isobolographic analysis proposed by Tallarida 10 was performed. Using ... Tallarida RJ: Drug Synergism and Dose-effect Data Analysis, 1st edition. Boca Raton, Chapman and Hall/CRC Press, 2000, pp 57-75 ... For each drug mixture, the ED50and their associated 95% CL were determined by linear regression analysis of the log dose- ... Assessment of psychomotor effects was made in separate groups of rats using the same protocol of drugs and doses (n = 5/group ...https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1943230
Monoclonal antibody to the ICAM-1 adhesion site reduces neurological damage in a rabbit cerebral embolism stroke model. |...
Drug Synergism. *Intercellular Adhesion Molecule-1. *Intracranial Embolism and Thrombosis (complications, pathology, ... Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find ...http://www.curehunter.com/public/pubmed8094342.do
Experimental study of new cerebral protective substances--functional recovery of severe, incomplete ischemic brain pretreated...
Brain Ischemia (drug therapy, physiopathology) *Cerebrovascular Circulation. *Dogs. *Drug Synergism. *Drug Therapy, Combination ... After pretreatment with the drugs, blood flow was reduced via the pump to 1/10 of the normal flow volume and 1 hr later, return ... Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find ... Subsequent changes in electrical activity were observed and the effects of the drugs evaluated. In the control group, no ...http://www.curehunter.com/public/pubmed6792553.do
Effects of Levamisole on Cocaine Self-Administration by Rats. - Free Online Library
Psychology and mental health Health aspects Drug interactions Research Pharmacological research Pharmacology, Experimental ... Tallarida, R. J. (2000). Drug synergism and dose-effect data analysis. Boca Raton: Chapman & Hall/CRC Press. Tallarida. C. S., ... Tallarida, R. J., Porreca, F., & Cowan, A. (1989). Statistical analysis of drug-drug and site-site interactions with ... it also seems reasonable to assume that the pretreatment drug increased the rewarding, or reinforcing, value of the other drug ...https://www.thefreelibrary.com/Effects+of+Levamisole+on+Cocaine+Self-Administration+by+Rats-a0521162779
Drug synergism: its detection and applications. J Pharmacol Exp Ther 2001;298:865-72. ... Only 40% of mice treated with the combination of both drugs did not develop any peritoneal disease, and in the ones who did, ... Huynh H, Soo KC, Chow PK, Panasci L, Tran E. Xenografts of human hepatocellular carcinoma: a useful model for testing drugs. ... It would be attractive to consider therapy with this combination of drugs in a palliative setting, where absence of ascites and ...http://mct.aacrjournals.org/content/6/11/2959
ICP-MS quantification of essential metals in Zip4intest | Open-i
Drug Synergism. *Humans. *Intestines/metabolism/pathology. *Liver/metabolism/pathology. *Mice. *Mice, Knockout ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3755987_pone.0072543.g007&req=4
2001) Drug synergism: its detection and applications. J Pharmacol Exp Ther 298:865-872. ... 2012) Emerging drugs for chronic obstructive pulmonary disease. Expert Opin Emerg Drugs 17:61-82. ... Analysis of Synergism Studies.. Analysis of the potential synergism between RPL554 plus salbutamol, RPL554 plus atropine, or ... Preparation of Drugs. The following drugs were used: acetylcholine (ACh), histamine, salbutamol, atropine, glycopyrrolate, ...http://jpet.aspetjournals.org/content/346/3/414
GPR119 agonist enhances gefitinib responsiveness through lactate-mediated inhibition of autophagy | Springer for Research &...
To assess the potential synergism of two drugs, 'isobole model' has been frequently used . In the isobole model, the ... Quantitative methods for assessing drug synergism. Genes Cancer. 2011;2(11):1003-8.CrossRefGoogle Scholar ... 2a). We also calculated the isobologram of the drug combination on MDA-MB-231 cells [a triple negative breast cancer (TNBC) ... Isobole model was used to evaluate drug combination effect. c Apoptosis induction by gefitinib with MBX-2982. Apoptosis was ...https://rd.springer.com/article/10.1186%2Fs13046-018-0949-2
Drug synergism: its detection and applications. J Pharmacol Exp Ther 2001;298:865-72 [review].. ... each drug should show a dose-effect relationship, at least three data points are required for each single drug effect, and the ... we chose only to analyze concurrent exposures because in patients treated with these drugs, continuous therapeutic drug levels ... Schedule-dependent synergism between raltitrexed and irinotecan in human colon cancer cells in vitro. Clin Cancer Res 1998;4: ...http://clincancerres.aacrjournals.org/content/11/9/3597
Cetuximab and Cisplatin Show Different Combination Effect in Nasopharyngeal Carcinoma Cells Lines via Inactivation of EGFR/AKT...
With this method, drug synergism was analyzed as follows : CI , 1 indicates a synergistic effect, CI = 1 an additive effect ... After 24 h of incubation, cells were treated with 2 mL of cetuximab (250 µg/mL), cisplatin (1 µg/mL), or the drug combination ... The two-drug regimen showed a significant synergistic effect in HNE1 cells but an additive effect in CNE2 cells. Our results ... Most cytotoxic chemotherapeutic drugs cause apoptosis in cancer cells. We demonstrated that the apoptosis rate of the ...https://www.hindawi.com/journals/bri/2016/7016907/
Dietary CQ with excess zinc in the drinking water (CQ/Z | Open-i
Drug Synergism. *Humans. *Intestines/metabolism/pathology. *Liver/metabolism/pathology. *Mice. *Mice, Knockout ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3755987_pone.0072543.g002&req=4
Superbugs & Superdrugs USA : Pharmaceuticals : All
11:40 The novel strategy to fight multidrug resistance by multiple drugs synergism, based on docking in drug design and TRIZ. ... Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 6.422.. ... DRUG DISCOVERY: Enable antibiotic drug development through novel approaches in treating gram-negative infections. TARGETING ... Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 6.422.. ...http://www.smi-online.co.uk/pharmaceuticals/archive/11-2016/conference/superbugs-superdrugs-usa?o=login&dl=cc&p1=5152&p2=619
Resistance Analysis and Characterization of a Thiazole Analogue, BP008, as a Potent Hepatitis C Virus NS5A Inhibitor |...
The interaction index: a measure of drug synergism. Pain 98:163-168. ... Dose selection and optimization therefore are essential in future drug development to ensure that certain liver drug levels are ... Implications of finding synergic in vitro drug-drug interactions between interferon-alpha and ribavirin for the treatment of ... drugs often have been shown to cause the emergence of drug-resistant mutations that lead to patients not responding to drug ...https://aac.asm.org/content/56/1/44
Venditti J, Goldin A. Drug synergism in antineoplstic chemotherapy. Adv Chemother 1964;13:397-498. ... The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular ... Study drugs and reagents. Ixabepilone and paclitaxel were synthesized in the Oncology Chemistry Department of Bristol-Myers ... Matrigel plug assays. The in vivo effects of each drug on angiogenesis were analyzed in mice using a VEGF/basic fibroblast ...http://clincancerres.aacrjournals.org/content/14/24/8123