Drug Screening Assays, Antitumor | ISHAR Online  Drug Screening Assays, Antitumor | ISHAR Online
The in vitro assays revealed that two naphthalene diimide-polyamine conjugates could inhibit the growth of multiple cancer cell ... Therefore, there is an urgent need for novel drugs with improved efficacy against tumor cells and with less toxicity on normal ... Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4. ... With the aim of up-regulating antitumor efficacy and down-regulating adverse effects, three types of aromatic imide and ...
more infohttp://isharonline.org/tags/drug-screening-assays-antitumor
A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces...  A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces...
DNA Damage / drug effects. Drug Screening Assays, Antitumor. HCT116 Cells. High-Throughput Screening Assays*. Humans. Indoles ... Apoptosis / drug effects*. Cell Line, Tumor. Cell Proliferation / drug effects. Cyclin D / metabolism. Cyclin-Dependent Kinase ... Title: Journal of biomolecular screening Volume: 16 ISSN: 1552-454X ISO Abbreviation: J Biomol Screen Publication Date: 2011 ... Previous Document: Comparison of Multivariate Data Analysis Strategies for High-Content Screening.. Next Document: An Improved ...
more infohttp://www.biomedsearch.com/nih/High-Throughput-Screen-with-Isogenic/21335596.html
Inhibition of pancreatic adenocarcinoma cell growth by lovastatin.  Inhibition of pancreatic adenocarcinoma cell growth by lovastatin.
Cell Survival / drug effects. Cricetinae. Dose-Response Relationship, Drug. Drug Screening Assays, Antitumor. Humans. ... 333026 - An improved plaque assay for mouse myeloma (mopc 315) cells for use in studies of humor.... 11532876 - Areca nut ... 3364936 - Inhibition of invasion activity in vitro by a novel class of antitumor agents: silatran.... 8083436 - Regulation of ...
more infohttp://www.biomedsearch.com/nih/Inhibition-pancreatic-adenocarcinoma-cell-growth/1499946.html
Evaluation of Drug Resistance in Patients With Metastatic Breast Cancer - Full Text View - ClinicalTrials.gov  Evaluation of Drug Resistance in Patients With Metastatic Breast Cancer - Full Text View - ClinicalTrials.gov
Drug: paclitaxel Other: antitumor drug screening assay Phase 2 Study Type:. Interventional ... Assay to determine probability of drug resistance to paclitaxel. After successful completion of the EDR assay (approximately 7 ... and low drug resistance to paclitaxel using the Extreme Drug Resistance (EDR) Assay in patients with previously treated ... Assessment of the Predictive Value of the Extreme Drug Resistance (EDR) Assay in Patients Receiving Paclitaxel for Metastatic ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT00003253
Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells...  Distribution and subcellular localization of a water-soluble hematoporphyrin-platinum(II) complex in human bladder cancer cells...
Drug Screening Assays, Antitumor. MESH. Hematoporphyrins/metabolism. MESH. Humans. MESH. Organoplatinum Compounds/chemistry. ...
more infohttps://epub.uni-regensburg.de/4827/
anal mucinous adenocarcinoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine  anal mucinous adenocarcinoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Drug Screening Assays, Antitumor / methods. Paclitaxel / pharmacology. *Genetic Alliance. consumer health - Breast Cancer. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ...
more infohttp://www.bmlsearch.com/?kwr=anal+mucinous+adenocarcinoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
ZFIN Publication: Santoriello et al., 2012  ZFIN Publication: Santoriello et al., 2012
Drug Screening Assays, Antitumor* (all 22) Animals; Central Nervous System Diseases/drug therapy; Central Nervous System ... Drug Screening Assays, Antitumor*; Eye Diseases/genetics; Female; Genetic Engineering; Heart Diseases/genetics; Heart Diseases/ ... Duchenne/drug therapy; Muscular Dystrophy, Duchenne/genetics; Neoplasms/drug therapy; Neoplasms/genetics; Zebrafish/anatomy & ... Animals; Central Nervous System Diseases/drug therapy; Central Nervous System Diseases/genetics; Disease Models, Animal*; ...
more infohttp://zfin.org/ZDB-PUB-120706-12
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25  - D...  Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25 - D...
... drug effects; Drug Screening Assays, Antitumor; Enzyme Inhibitors--chemical synthesis; Enzyme Inhibitors--chemistry; Enzyme ... Using a chemical complementation assay, we found that NSC 663284 blocked cellular Erk dephosphorylation caused by ectopic ...
more infohttp://d-scholarship.pitt.edu/20472/
The development of N-alpha-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoe by Corey P. Causey, Justin E. Jones et al.  "The development of N-alpha-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoe" by Corey P. Causey, Justin E. Jones et al.
Drug Screening Assays, Antitumor; Drug Synergism; Humans; Hydrolases; Kinetics; Molecular Structure; Ornithine; Structure- ...
more infohttps://escholarship.umassmed.edu/thompson/44/
Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia -...  Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia -...
Antitumor Drug Screening Assay Undergo pre clinical kinase inhibitor activity screening. Other Name: Drug Screening Assays, ... Antitumor Drug Screening Assay Undergo pre clinical kinase inhibitor activity screening. Other Name: Drug Screening Assays, ... Antitumor Drug Screening Assay Undergo pre clinical kinase inhibitor activity screening. Other Name: Drug Screening Assays, ... Antitumor Drug Screening Assay Undergo pre clinical kinase inhibitor activity screening. Other Name: Drug Screening Assays, ...
more infohttps://clinicaltrials.gov/show/NCT01620216
MeSH Semantic Type: Cell [T025]  MeSH Semantic Type: Cell [T025]
These cells are used for VIRUS CULTIVATION and antitumor drug screening assays. ... It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals. ... used primarily in virus replication studies and plaque assays. ... mechanism of differential susceptibility to anti-cancer drugs ...
more infohttp://www.slicksurface.com/medical-thesaurus/semantic-type/cell.htm
urinary tract neoplasms benign drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine  urinary tract neoplasms benign drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
MeSH-minor] Breast Neoplasms / drug therapy. Cell Line, Tumor. Drug Screening Assays, Antitumor. Female. HCT116 Cells. Humans. ... Prostatic Diseases / drug therapy. Prostatic Hyperplasia / drug therapy. Prostatic Neoplasms / drug therapy. Prostatitis / drug ... Urologic Diseases / drug therapy. *[MeSH-minor] Clinical Trials as Topic. Dose-Response Relationship, Drug. Drug Evaluation, ... Prostatic Hyperplasia / drug therapy. Prostatic Neoplasms / drug therapy. Sulfonamides / pharmacology. Urinary Retention / drug ...
more infohttp://www.bmlsearch.com/?kwr=urinary+tract+neoplasms+benign+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
Computationally Assisted Assignment of the Kadsuraols, a Class of Chem by Xiaojuan Wang, Jiabao Liu et al.  "Computationally Assisted Assignment of the Kadsuraols, a Class of Chem" by Xiaojuan Wang, Jiabao Liu et al.
The compounds showed no cytotoxicity at 10 μM in a zone assay. ... Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Kadsura ... The compounds showed no cytotoxicity at 10 μM in a zone assay. ...
more infohttps://scholarlycommons.henryford.com/hematologyoncology_articles/57/
sg:pub.10.1186/1476-4598-5-67 - Springer Nature SciGraph  sg:pub.10.1186/1476-4598-5-67 - Springer Nature SciGraph
"Drug Screening Assays, Antitumor", "type": "DefinedTerm" }, { "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", "name": " ... Tumour stem cells and drug resistance in NATURE REVIEWS CANCER. *2002-05. Dysregulation of apoptosis genes in hematopoietic ... The gene expression and the drug resistance property of CD133 positive cancer stem cells, however, are still unknown. RESULTS: ... The gene expression and the drug resistance property of CD133 positive cancer stem cells, however, are still unknown. RESULTS: ...
more infohttps://scigraph.springernature.com/pub.10.1186/1476-4598-5-67
Spiral: Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the...  Spiral: Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the...
Drug Screening Assays, Antitumor. False Positive Reactions. Humans. Lipoproteins. Metabolomics. Neoplasms. Oligonucleotide ...
more infohttps://spiral.imperial.ac.uk:8443/handle/10044/1/53155
a) Single-crystal X-ray structure of 17 f. Ellipsoids a | Open-i  a) Single-crystal X-ray structure of 17 f. Ellipsoids a | Open-i
Cell Proliferation/drug effects. *Dose-Response Relationship, Drug. *Drug Screening Assays, Antitumor ... The broad anticancer activity of DHIQ 16 g was confirmed in the NCI 60-cell line assay giving a mean activity of 33 nM. ... The broad anticancer activity of DHIQ 16 g was confirmed in the NCI 60-cell line assay giving a mean activity of 33 nM. ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4114533_cmdc-9-798-f3&req=4
RASAL1 | Cancer Genetics Web  RASAL1 | Cancer Genetics Web
Drug Screening Assays, Antitumor. *Epigenetics. *Genes, Neoplasm. *Cancer Gene Expression Regulation. *Loss of Heterozygosity ... Invest New Drugs. 2010; 28(2):107-14 [PubMed] Related Publications The activity of the histone deacetylase inhibitor PXD101 was ... A transfection assay showed that RASAL1 repressed RAS/mitogen-activated protein kinase signaling in response to growth factor ... RESULTS: Among 13 negative modulators of the RAS pathway screened, RASAL1, encoding a RAS GTPase-activating protein, was ...
more infohttp://cancer-genetics.org/RASAL1.htm
Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high...  Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high...
Dose-Response Relationship, Drug * Drug Screening Assays, Antitumor * Flow Cytometry * Humans * Intracellular Space ... A cell-based assay was developed to screen for small molecule inducers of intracellular granularity using the HyperCyt high- ... A further screen of approximately 25,000 small molecules led to the identification of a class of aryl-oxazoles that increased ...
more infohttps://vivo.health.unm.edu/display/n2071260525
OPUS at UTS: Antiproliferative and antimigratory actions of synthetic long chain n-3 monounsaturated fatty acids in breast...  OPUS at UTS: Antiproliferative and antimigratory actions of synthetic long chain n-3 monounsaturated fatty acids in breast...
Drug Combinations. en_US. dc.subject.mesh. Drug Screening Assays, Antitumor. en_US. ... We tested the hypothesis that these antitumor actions of n-3 PUFA may involve the n-3 olefinic bond. n-3 Monounsaturated fatty ... We tested the hypothesis that these antitumor actions of n-3 PUFA may involve the n-3 olefinic bond. n-3 Monounsaturated fatty ... Drug Combinations. en_US. dc.subject.mesh. Drug Screening Assays, Antitumor. en_US. ...
more infohttps://opus.lib.uts.edu.au/handle/10453/28484