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*  Patent US6691045 - Method for determining discrete quantitative structure activity relationships - Google Patents
The present invention is applied below to a drug discovery problem, the analysis of estrogen receptor ligands. ... A protein identified in a search for a chemical compound (drug) that can affect a disease or its symptoms is called a target. ... This process has allowed a brute-force approach to ligand discovery. The hypothesis phase consists of obtaining large ... and whose function can be interfered with by a drug. ...
http://www.google.com/patents/US6691045?dq=5,960,411
*  中国科学院大连化学物理研究所机构知识库(DICP OpenIR): 3D-QSAR and Molecular Docking Studies on Derivatives of MK-0457, GSK1070916 and SNS
Aurora B ; drug design ; 3D-QSAR ; CoMFA ; CoMSIA ; molecular docking ; homology modeling ... 3.Chinese Acad Sci, Grad Sch, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Liaoning, Peoples R ... Development of anticancer drugs targeting Aurora B, an important member of the serine/threonine kinases family, has been ... Taken together, the results will serve as a basis for future drug development of inhibitors against Aurora B kinase for various ...
http://cas-ir.dicp.ac.cn/handle/321008/141950
*  Nature Reviews Drug Discovery
... is a journal for people interested in drug discovery and development. It features reviews, news, ... Trends in GPCR drug discovery: new agents, targets and indications G protein-coupled receptors (GPCRs) are the most intensively ... Drug discovery effectiveness from the standpoint of therapeutic mechanisms and indications Shih and colleagues analyse ... This article presents a pioneering analysis of all GPCR-targeted drugs and agents that are currently in clinical trials, and ...
http://www.nature.com/nrd/?error=cookies_not_supported&code=43f62932-568e-4e7a-81de-8c843235ebd8
*  Drug Discovery
Neglected Diseases and Drug Discovery Neglected Diseases and Drug Discovery Neglected Diseases and Drug Discovery 04 Nov 2011 ... Drug Discovery from Natural Products Drug Discovery from Natural Products Drug Discovery from Natural Products 13 Sep 2012 ... Kinase Drug Discovery: Modern Approaches Kinase Drug Discovery: Modern Approaches Kinase Drug Discovery: Modern Approaches 06 ... Drug Discovery for Psychiatric Disorders Drug Discovery for Psychiatric Disorders Drug Discovery for Psychiatric Disorders 02 ...
http://pubs.rsc.org/bookshop/collections/series?issn=2041-3203
*  Animation : Nature Reviews Drug Discovery
Nature Reviews Drug Discovery has full responsibility for all editorial content, including NatureVideo content. This content is ... This animation, created by Nature Reviews Drug Discovery, explores the key aspects of the altered metabolism in cancer cells ...
http://www.nature.com/nrd/multimedia/cancermetab/index.html?error=cookies_not_supported&code=d0bb1b2d-548f-4d4a-91bf-f7a57e3aaba4
*  Optimization in Drug Discovery | SpringerLink
Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including ... Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down ... Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in ... drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo- ...
https://link.springer.com/book/10.1007/978-1-62703-742-6
*  Drug Discovery and Evaluation | SpringerLink
The rapid progress in biology will continue to change the methodological approach to drug discovery in the coming years. ... Drug Discovery and Evaluation:Pharmacological Assays bridges this gap by comprehensively covering the pharmacological methods ... The rapid progress in biology will continue to change the methodological approach to drug discovery in the coming years. ... Arzneimittel Arzneimittelwirkungen Pharmakologie Toxikologie Wirkstoffe Wirkstoffforschung assays drug action drugs ...
https://link.springer.com/referencework/10.1007/978-3-540-70995-4
*  Drug discovery and development process - YouTube
Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development ... Innovative drug discovery speeds new treatments to patients - Duration: 3:11. Novartis 10,283 views ... Learn about the many different steps in the complex drug discovery and development process.. © 2011 Novartis AG ... Discovering and bringing one new drug to the market typically takes an average of 14 years of research and clinical development ...
https://www.youtube.com/watch?v=3Gl0gAcW8rw&feature=relmfu
*  Diamond Lab - Drug Discovery
Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening. PLoS One 2011; 6 (10): e26169 ... Nanoliter homogenous ultra-high throughput screening microarray for lead discoveries and IC50 profiling. Assay Drug Dev Technol ... Drug Discovery. High throughput screening is the process where a large chemical library is screened for activity in an assay, ... Assay Drug Dev Technol 2008; 6 (3): 395-405 10. Myers MC, Shah PP, Beavers MP, Napper AD, Diamond SL, Smith AB, 3rd, Huryn DM. ...
https://www.seas.upenn.edu/~diamond/drug-discovery.html
*  Biomolecular condensates pique drug discovery curiosity
... Transient liquid-like droplets made up of proteins and RNA are ... Researchers have their work cut out for them to get a better grasp on what this all might mean for drug discovery. What targets ... Brangwynne is moving towards commercializing his tools for therapeutic and drug discovery applications, and says he has had ... "My personal opinion is that as the field matures, no drug company should feel comfortable taking a drug candidate into clinical ...
https://www.nature.com/articles/d41573-019-00069-w?error=cookies_not_supported&code=55fda7c4-4a42-4d97-bdb5-fcee03a2c984
*  Drug discovery: creating a new ecosystem
... : Programme. Day 1 , 2nd June 2016 :. Opening. Plenary talk I. Session 1: 'The new era ... Session 3: 'The impact of chemical biology in drug discovery: how far can we push it?'. Day 2 , 3rd June 2016 :. Plenary talk ... Drug discovery: creating a new ecosystem. 2 June 2016 09:00 - 3 June 2016 18:00, Oxford, United Kingdom ... This provocative meeting is intended to bring together all those concerned about drug discovery (academia, industry, biotech, ...
http://www.rsc.org/events/detail/22594/drug-discovery-creating-a-new-ecosystem
*  Drug Discovery : Pharmaceuticals : UK
Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 6.422.. ... This will assist rational, fast and successful drug discovery.. Drug Discovery 2018 provides an unprecedented opportunity to ... Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 6.422.. ... Drug Discovery Today will benefit your research by helping to keep you up-to-date with all of the fast-moving and emerging ...
http://www.smi-online.co.uk/pharmaceuticals/uk/drug-discovery?utm_medium=www.drug-discovery.co.uk&utm_source=P-218&utm_campaign=evvnt
*  Drug Discovery : Pharmaceuticals : UK
Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by ... This will assist rational, fast and successful drug discovery.. Drug Discovery 2018 provides an unprecedented opportunity to ... Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by ... 16:30 Disrupting drug discovery with AI. Mark Davies, Vice President, Biomedical Informatics, BenevolentAI. View Bio. Mark is ...
https://www.smi-online.co.uk/pharmaceuticals/uk/drug-discovery
*  Griffith Institute for Drug Discovery
Directions in drug discovery. Delve deeper into our research and find out more about our approaches, innovation and ... Griffith Institute for Drug Discovery (GRIDD). Professor Emeritus Alan Mackay-Sim, Australian of the Year 2017 ... Our unique resources, dedicated researchers and international partners create an ideal context for drug discovery that drives ... We are also proud to foster the next generation of drug discovery scientists. ...
https://www.griffith.edu.au/institute-drug-discovery
*  Drug Discovery Research
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields ... All Topics Biotechnology Biotech Business Biotech Products Cancer Cardiovascular Dermatology Drug Discovery Endocrinology ... All Topics Biotechnology Biotech Business Biotech Products Cancer Cardiovascular Dermatology Drug Discovery Endocrinology ... review and buy Drug Discovery market research data and corporate reports here ...
https://www.bioportfolio.com/drug-discovery/research/
*  Drug Discovery Chemistry : Pharmaceuticals : UK
Drug Discovery Today is one of the most cited review journals in the field of drug discovery, with an impact factor of 6.422.. ... 15:50 Next-Generation drug discovery: quantum physics meets machine learning. Graham Simpson, Head of Drug Discovery, GTN Ltd. ... Sr Vice President Drug discovery & Platform Sciences, Berg LLC. In his role of Sr Vice President, Drug Discovery & Platform ... 11:40 Using Artificial intelligence in early drug discovery. Vivek Vishnudas, Sr Vice President Drug discovery & Platform ...
http://www.smi-online.co.uk/pharmaceuticals/uk/Drug-Discovery-UK?utm_medium=www.drug-discovery.co.uk&utm_source=P-279&utm_campaign=PharmaNewsHQwb&o=login&dl=cc&p1=5444&p2=1536
*  Drug Discovery Chemistry : Pharmaceuticals : UK
11:40 Next-Generation Drug Discovery: Quantum Physics Meets Machine Learning. Graham Simpson, Head of Drug Discovery, GTN Ltd. ... Sr Vice President Drug discovery & Platform Sciences, Berg LLC. In his role of Sr Vice President, Drug Discovery & Platform ... 9:10 Using Artificial intelligence in early drug discovery. Vivek Vishnudas, Sr Vice President Drug discovery & Platform ... 15:20 Cryo-EM in drug discovery - advances in technology and its impact on furture drug discovery prospects. ...
http://www.smi-online.co.uk/pharmaceuticals/uk/Drug-Discovery-UK
*  Drug Discovery Chemistry : Pharmaceuticals : UK
Selvita is a global integrated drug discovery CRO specialising in variety of drug discovery processes from in silico drug ... Selvita is a global integrated drug discovery CRO specialising in variety of drug discovery processes from in silico drug ... Sr Vice President Drug discovery & Platform Sciences, Berg LLC. In his role of Sr Vice President, Drug Discovery & Platform ... Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by ...
http://smi-online.co.uk/pharmaceuticals/uk/conference/Drug-Discovery-UK?o=login&dl=cc&p1=5444&p2=1676
*  drug discovery | Page 2 | University of Cambridge
30 million Drug Discovery Alliance, launching three flagship Drug Discovery Institutes at the Universities of Cambridge, Oxford ... Discovery of new structure of cell's communication channel could aid drug development. 28 Apr 2014 The structure of sodium ... Researchers hope their discovery will lead to improvements in drugs that act on the sodium channel to treat a range of cardiac ... Cambridge Drug Discovery Institute to fast-track development of new treatments for dementia. 16 Feb 2015 Alzheimer's Research ...
https://www.cam.ac.uk/subjects/drug-discovery?page=1
*  Microplates | Microplates for Drug Discovery | Corning
... microplates are ideal for drug discovery applications, including assay prep, assay development, and HTS and automation. ... Designed to the highest standards to support your drug discovery research, Corning® and Falcon® microplates are ideal for drug ... Microplates , Microplates for Drug Discovery , Corning. We use cookies to ensure the best experience on our website. ... Our Drug Discovery Sales Specialists are available to assist you with any product selection questions or purchase requests. ...
https://www.corning.com/worldwide/en/products/life-sciences/products/microplates.html
*  Drug Discoveries & Therapeutics
... Published by International Research and Cooperation Association for Bio & Socio-Sciences ... Erratum for 'Anesthetic activity of plant essential oils on Cyprinus carpio (koi carp)' (Drug Discoveries & Therapeutics. 2018 ... Criteria for the selection of switch OTC drugs based on patient benefits, efficacy, and safety [II]: Comparing the ...
https://www.jstage.jst.go.jp/browse/ddt
*  Combinatorial drug discovery in nanoliter droplets | PNAS
Combinatorial drug discovery in nanoliter droplets. Anthony Kulesa, Jared Kehe, Juan E. Hurtado, Prianca Tawde, Paul C. Blainey ... Combinatorial drug discovery in nanoliter droplets. Anthony Kulesa, Jared Kehe, Juan E. Hurtado, Prianca Tawde, Paul C. Blainey ... Combinatorial drug discovery in nanoliter droplets. Anthony Kulesa, Jared Kehe, Juan E. Hurtado, Prianca Tawde, and Paul C. ... The use of multiple drugs in combination might improve desired functional outcomes while reducing toxicity and overcoming drug ...
http://www.pnas.org/content/115/26/6685
*  Drug discovery - Wikipedia
The "final product" of drug discovery is a patent on the potential drug. The drug requires very expensive Phase I, II and III ... Drug Discovery. 9 (3): 203-14. doi:10.1038/nrd3078. PMID 20168317. Warren J (April 2011). "Drug discovery: lessons from ... Antitarget Bioinformatics Biomedical informatics Cheminformatics Drug discovery hit to lead Drug metabolism Fragment-based drug ... Dynamic combinatorial diversity in drug discovery". In Jahnke W, Erlanson DA. Fragment-based approaches in drug discovery. ...
https://en.wikipedia.org/wiki/Drug_discovery