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*  A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy Volunteers -...
This randomized, open-label, crossover study will evaluate the relative bioavailability of ritonavir-boosted danoprevir fixed dose combination tablets (FDC) as compared to ad hoc combination of reference tablets of danoprevir and ritonavir in healthy volunteers. Subjects will be randomized to 1 of 6 treatment sequences to receive single oral doses of either an FDC of danoprevir and ritonavir or danoprevir and ritonavir as separate tablets. In a crossover design, subjects will participate in 3 study periods with at least a 7-day washout between periods. In Part 2, single dose administration of film-coated FDCs will be compared to reference tablets ...
https://clinicaltrials.gov/ct2/show/NCT01592318
*  Dr. Reckeweg - Germany Biochemic Combination Tablets BC08 for Diarrhoea - 20gm Tablets, Buy Dr. Reckeweg - Germany Biochemic...
Buy Dr. Reckeweg - Germany Biochemic Combination Tablets BC08 online Fast & Free Worldwide Shipping to USA, UK, Canada, Australia, Japan, France, Germany, Spain, Brazil and Russia. Easy and Secure payment through PayPal, Credit Card, Bank transfer.
https://www.ayurvedabay.com/dr-reckeweg-germany-biochemic-combination-tablets-bc08.html
*  Fixed Dose Combination Drug (Polypill)for Secondary Cardiovascular Prevention. - Full Text View - ClinicalTrials.gov
The aim of the FOCUS project is to test the Fixed Dose Combination concept for cardiovascular prevention in populations of different socio-economic characteristics. At the same time, FOCUS aims to understand the factors determining inappropriate prescribing for secondary cardiovascular prevention and those for poor patients adherence to treatment. This will allow FOCUS to establish recommendations for a better use of medication in patients with ischemic heart disease. In addition, after a successful completion of FOCUS, secondary prevention medication will be available and affordable for a large number of patients in both developed as well as developing countries.. There are two Phases in this study:. Phase 1: Is a descriptive, non interventional study. Phase 2: Is an interventional, randomized trial with prospective economic evaluation. ...
https://clinicaltrials.gov/ct2/show/NCT01321255?term=16606817+%5BPUBMED-IDS%5D&rank=1
*  Matrigel Matrix 100 mm Culture Dishes for Hepatocytes from BD Biosciences - Discovery Labware
... ,BD BioCoat BD MatrigelTM Matrix 100 mm Culture Dishes for hepatocytes, tissue-culture treated polystyrene with a uniform application of MATRIGEL Matrix.,biological,biology supply,biology supplies,biology product
http://www.bio-medicine.org/biology-products/Matrigel-Matrix-100-mm-Culture-Dishes-for-Hepatocytes-from-BD-Biosciences---Discovery-Labware-2466-1/
*  s ꒲ | [ g: E ̑ ܍ s
Fixed-dose combination drugs have been used for some time in certain therapeutic categories such as antihypertensives, although they were often reserved for second- or third-line therapy. With the revolution in the survival rates of patients suffering from human immunodeficiency virus (HIV) infection that occurred with the implementation of fixed-drug combination products for this, this delivery technology received a boost of confidence as well as an influx of creative applications to other diseases. For the past several years, a number of fixed-dose combination drugs have been introduced for a variety of diseases, some for the first time in a particular disease category. With this in mind, this STIX Market Research report focuses on the impact of fixed-dose combination drug technology on various therapeutic categories, as well as providing assessments and projections of this technology overall and the impact on the patient compliance and ...
https://www.gii.co.jp/report/stix304371-global-market-fixed-dose-combination-drugs.html
*  Fixed-combination glaucoma agent yields positive safety, efficacy data | OphthalmologyTimes
A phase III trial for the fixed-combination netarsudil/latanoprost agent (Roclatan, Aerie Pharmaceuticals)reports positive results. The company plans to submit a NDA for the drug in early 2018.
http://ophthalmologytimes.modernmedicine.com/ophthalmologytimes/news/fixed-combination-glaucoma-agent-yields-positive-safety-efficacy-data?page=0%2C0
*  HIV Alert! | MATEC
U.S. Food & Drug Administration (FDA), April 5, 2016.. On April 4, 2016 FDA approved DESCOVY, a two-drug fixed dose combination tablet containing 2 HIV nucleoside analog reverse transcriptase inhibitors (NRTIs), emtricitabine (FTC) and tenofovir alafenamide (TAF). Each DESCOVY tablet contains 200 mg of FTC and 25 mg of TAF (equivalent to 28 mg of tenofovir alafenamide fumarate).. DESCOVY is not a complete regimen for the treatment of HIV-1 infection and must be combined with other antiretroviral agents to form a complete regimen.. The approval is based on a relative bioavailability trial demonstrating FTC and TAF exposures were similar between DESCOVY and GENVOYA (elvitegravir/cobicistat/FTC/TAF). A clinical trial to evaluate the efficacy and safety of DESCOVY was not required because the safety and efficacy of FTC and TAF was established previously in clinical trials with GENVOYA.. TAF 25 mg provides for TAF exposures that match or exceed those observed in patients ...
http://www.matec.info/news/hiv-alert
*  Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically...
The mean (SD) change of the overall EFV-related symptom assessment score is presented. The overall symptom score (ranging from 0 to 20) is the sum of the individual symptom scores ranging from 0 (no symptoms) to 4 (most severe symptoms) from the 5 EFV-related symptom assessments (dizziness, trouble sleeping, impaired concentration, sleepiness, and abnormal or vivid dream).. EFV-Related Symptom Analysis Set: participants who received EFV/FTC/TDF as prior treatment, received at least 1 dose of study drug, and completed EFV-related symptom assessments at the baseline visit and at least 1 postbaseline visit. ...
https://clinicaltrials.gov/ct2/show/record/NCT01815736?view=results
*  Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically...
The mean (SD) change of the overall EFV-related symptom assessment score is presented. The overall symptom score (ranging from 0 to 20) is the sum of the individual symptom scores ranging from 0 (no symptoms) to 4 (most severe symptoms) from the 5 EFV-related symptom assessments (dizziness, trouble sleeping, impaired concentration, sleepiness, and abnormal or vivid dream).. EFV-Related Symptom Analysis Set: participants who received EFV/FTC/TDF as prior treatment, received at least 1 dose of study drug, and completed EFV-related symptom assessments at the baseline visit and at least 1 postbaseline visit. ...
https://clinicaltrials.gov/show/NCT01815736?order=164
*  Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically...
The mean (SD) change of the overall EFV-related symptom assessment score is presented. The overall symptom score (ranging from 0 to 20) is the sum of the individual symptom scores ranging from 0 (no symptoms) to 4 (most severe symptoms) from the 5 EFV-related symptom assessments (dizziness, trouble sleeping, impaired concentration, sleepiness, and abnormal or vivid dream).. EFV-Related Symptom Analysis Set: participants who received EFV/FTC/TDF as prior treatment, received at least 1 dose of study drug, and completed EFV-related symptom assessments at the baseline visit and at least 1 postbaseline visit. ...
https://clinicaltrials.gov/show/NCT01815736?order=455
*  Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically...
The mean (SD) change of the overall EFV-related symptom assessment score is presented. The overall symptom score (ranging from 0 to 20) is the sum of the individual symptom scores ranging from 0 (no symptoms) to 4 (most severe symptoms) from the 5 EFV-related symptom assessments (dizziness, trouble sleeping, impaired concentration, sleepiness, and abnormal or vivid dream).. EFV-Related Symptom Analysis Set: participants who received EFV/FTC/TDF as prior treatment, received at least 1 dose of study drug, and completed EFV-related symptom assessments at the baseline visit and at least 1 postbaseline visit. ...
https://clinicaltrials.gov/show/NCT01815736?order=65
*  D-M - Diazepam and Methohexital (drug combination) | AcronymFinder
How is Diazepam and Methohexital (drug combination) abbreviated? D-M stands for Diazepam and Methohexital (drug combination). D-M is defined as Diazepam and Methohexital (drug combination) very rarely.
https://www.acronymfinder.com/Diazepam-and-Methohexital-
*  Several Fixed-dose Drug Combinations Sold in India Lack Regulatory Approval
Fixed-dose drug combinations are used to treat conditions like Parkinson s, HIV, malaria and tuberculosis, but these drugs lack approval and could put patients' lives at risk.
http://www.medindia.net/news/several-fixed-dose-drug-combinations-sold-in-india-lack-regulatory-approval-149097-1.htm
*  Integrated Computational and Experimental Approaches for Accelerated Drug Combination Discovery and Development : Applications...
Today the norm in modern cancer treatment is to use different forms of drug combinations. Recently anti-cancer treatment using drug combinations has gained increased attention due to the outstanding pharmacotherapeutic opportunities provided by combination therapies. However, the potential of this field is largely unexplored, partly due to the complexities associated with the astronomical number of possible combinations and partly due to the lack of means for quantifying clinically relevant adverse side effects in the early stages of the combination discovery and development process. This has resulted in relatively limited progress in this area. Motivated by this unfortunate state-of-affairs, the research reported in this thesis was aimed at developing and implementing computational and experimental methods to facilitate and accelerate the discovery and development of anti-cancer therapies. In paper I, the largely overlooked ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:791212
*  India: The Pharmacy of the World Where 'Crazy Drug Combinations' Go Unregulated
Thousands of fixed dose combination (FDC) drugs - where two or more drugs are combined in a set ratio in a single dose form, usually a tablet or capsule - are formulated, made and sold within India.
http://scitechconnect.elsevier.com/india-pharmacy-crazy-drug-combos/
*  Two-drug combination may boost immunotherapy responses in lung cancer patients
These so-called epigenetic therapy drugs, used together, achieved robust anti-tumor responses in human cancer cell lines and mice.
http://www.saferadiotherapy.com/two-drug-combination-may-boost-immunotherapy-responses-lung-cancer-patients/
*  CME Fixed-Dose Combination Therapy With Daclatasvir, Asunaprevir, and Beclabuvir for Noncirrhotic Patients With HCV Genotype 1...
Please provide below the URL and description of an activity you would like to add to OpenCME. You are welcome to add activities as often as you like. To prevent spam or other abuse, activities are reviewed by our editorial team before appearing on OpenCME. ...
http://opencme.org/course/fixed-dose-combination-therapy-daclatasvir-asunaprevir-and-beclabuvir-noncirrhotic-patients-h
*  Corning® Matrigel® Matrix: Material Properties, Applications and Proper Usage
The extracellular matrix (ECM) is a complex material that serves to stabilize tissues, promote cell attachment, and modulate cell functionality by specifically interacting with cell surface receptors. This material has been shown to play structural, bioch...
https://www.brighttalk.com/webcast/6639/111307
*  drug combination | Tag | PBS NewsHour
The Food and Drug Administration gave the go-ahead Thursday to a drug combination called Truvada that is aimed at preventing the spread of HIV. Until now, it had only approved drugs for treating the disease. Ray Suarez discusses the details with Dr. Anthony Fauci of the National Institute of Allergies and Infectious Diseases. Continue reading →. ...
http://www.pbs.org/newshour/tag/drug-combination/