biotechnology | Journal of The Royal Society Interface
Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules. ...http://rsif.royalsocietypublishing.org/collection/biotechnology?page=5
Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules | Journal of The...
Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules. Ming-Wei Chang ... Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules ... Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules. ... Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules ...http://rsif.royalsocietypublishing.org/content/early/2010/10/08/rsif.2010.0428
Journal of The Royal Society Interface
It is envisioned that this drug will be manufactured when desired by astronauts using bacteria that are activated from a frozen ... 2009 Enrichment of a mixed bacterial culture with a high polyhydroxyalkanoate storage capacity. Biomacromolecules 10, 670-676 ... In this paper, a versatile drug to treat infection and pain symptoms, e.g. aspirin, acetaminophen, etc., is targeted for ... The bacteria will not themselves 'expire' from space radiation because of storage in a small, lead-lined container while ...http://rsif.royalsocietypublishing.org/content/12/102/20140715.full
Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases | Journal of The...
In library-screening mode there is a direct mapping from storage plates to assay plates, and a single transfer volume is used ... Drug screening for drug repositioning. We then applied the assays to the challenge of drug repositioning-the application of ... 2010 Emergence of orphan drugs in the United States: a quantitative assessment of the first 25 years. Nat. Rev. Drug Disc. 9, ... Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases. Kevin Williams, ...http://rsif.royalsocietypublishing.org/content/12/104/20141289
Hovering performance of Anna's hummingbirds (Calypte anna) in ground effect | Journal of The Royal Society Interface
We additionally used a profile drag coefficient of 0.139 based on the drag measurements made on a revolving hummingbird wing at ... Total mechanical power output, assuming perfect elastic storage, Pmech , was calculated for three birds as the sum of the ... assuming a constant drag coefficient of 0.139) represents only 20-25% of total power, but if the profile drag out of ground ... Relevant unsteady drag data for hummingbird wings flapping at different angles of attack are in any event unavailable, but we ...http://rsif.royalsocietypublishing.org/content/11/98/20140505
Journal of The Royal Society Interface
2007 Iron storage in neurovesicles revealed by chemical nano-imaging. PLoS ONE 2, e925. (doi:10.1371/journal.pone.0000925). ... μ-XANES was also applied to the chemical speciation of platinum anti-cancer drugs (Hall et al. 2003), showing that Pt(IV) ... 2002 Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc. Natl Acad. Sci ... The knowledge of the intracellular distribution of metal-based drugs is important in order to verify that they reach their ...http://rsif.royalsocietypublishing.org/content/6/Suppl_5/S649.long
Controlled cobalt doping in biogenic magnetite nanoparticles | Journal of The Royal Society Interface
... targeted drug delivery , magnetic data storage  and magnetic thermotherapy targeting cancerous tumours [8-10]. ... 2000 Locoregional cancer treatment with magnetic drug targeting. Cancer Res. 60, 6641-6648. ...http://rsif.royalsocietypublishing.org/content/10/83/20130134
Fick's second law transformed: one path to cloaking in mass diffusion | Journal of The Royal Society Interface
This has benefits such as drug mobility. The release of the drug-enriched core of SLN is based on Fick's first law of diffusion ... This could be followed by frozen storage before consequent steps. Second, replacing the classical hydration step by using an ... 2003 Lateral diffusion rates of lipid, water, and a hydrophobic drug in a multilamellar liposome. Biophys. J. 85, 1734-1740. ... Using the diffusivity values published for a certain lipid-conjugated drug (1.9 × 10−11 m s−2 for dehydrated 1-palmitoyl-2- ...http://rsif.royalsocietypublishing.org/content/10/83/20130106
Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects | Journal of The Royal...
Meanwhile drug delivery systems (DDS) are one of the most typical biomedical applications of nanoparticles being developed ( ... The development of applications in the electronic and chemical fields such as field emission electron gun and hydrogen storage ... Drug Discov. Today Ther. Strateg. 5, 87-92. doi:10.1016/j.ddstr.2008.06.002. ... Drug Deliv. Rev. 60, 1226-1240. doi:10.1016/j.addr.2008.03.015. ... 1.6 Nanoparticle internal diffusion and drug delivery systems. ...http://rsif.royalsocietypublishing.org/content/6/Suppl_3/S371
Extremely fast prey capture in pipefish is powered by elastic recoil | Journal of The Royal Society Interface
2.3.4 Drag. The total moment of force due to hydrodynamic drag equals the summation of the moments for the individual ... 2006 Storage and recovery of elastic potential energy powers ballistic prey capture in toads J. Exp. Biol. 209, 2535-2553. doi: ... The drag force on the body was calculated by. (2.18)where civ0 is the linear velocity of a given section of the body and liwi ... This drag coefficient is also a function of Reynolds number (Re): for external flow over smooth cylinders, Cd will drop off ...http://rsif.royalsocietypublishing.org/content/5/20/285
Directed evolution of bacteriorhodopsin for applications in bioelectronics | Journal of The Royal Society Interface
2012 Nanotech revolution for the anti-cancer drug delivery through blood-brain-barrier. Curr. Cancer Drug Tar. 12, 186-196. doi ... the transient nature of the M state precludes the design of a long-term data storage device based on this scheme. The branched ... Drug Discov. Today 8, 118-126. doi:10.1016/S1359-6446(02)02590-4 (doi:10.1016/S1359-6446(02)02590-4). ... 2012 Nanotechnology-based drug delivery in mucosal immune diseases: hype or hope? Mucosal Immunol. 5, 1-3. doi:10.1038/mi. ...http://rsif.royalsocietypublishing.org/content/10/84/20130197
Odour character differences for enantiomers correlate with molecular flexibility | Journal of The Royal Society Interface
This is especially an issue for enantiomers, since impurities may arise in synthesis, or during storage before use, as a result ... Such situations appear to describe many cases of large drug molecules interacting with receptors. In the other class, the ' ...http://rsif.royalsocietypublishing.org/content/6/30/75
A comparison of hyperelastic constitutive models applicable to brain and fat tissues | Journal of The Royal Society Interface
The dynamic shear storage modulus G′ was measured as a function of time (brain: 2% oscillatory shear strain, 2 rad s−1 ... particularly for the design of needle-free drug-delivery systems . ... where G′ is the storage modulus and λ is the axial strain. To determine the linear viscoelastic region for each tissue, the ... The dynamic shear storage modulus G′ was measured as a function of time for increasing tensile or compressive strain (from 0% ...http://rsif.royalsocietypublishing.org/content/12/110/20150486
Passive versus active engulfment: verdict from trajectory simulations of lunge-feeding fin whales Balaenoptera physalus |...
3.3 Shape drag and total drag. The drag associated with the changing shape of a lunging whale (figure 1) and the external flows ... shows a somewhat greater elastic energy storage capacity, which is reached only during 130-270% strain, prior to an exponential ... This contrasts with merging both engulfment drag and shape drag into a single drag force of the V2 type, where V represents ... Total drag (dashed line) is the sum of external drag (thin solid line) and engulfment drag (thick solid line). ...http://rsif.royalsocietypublishing.org/content/early/2009/02/09/rsif.2008.0492
Customized Ca-P/PHBV nanocomposite scaffolds for bone tissue engineering: design, fabrication, surface modification and...
2008 Controlled drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 60, 229-242. (doi:10.1016/j.addr.2007.08.038). ... Storage Process. Syst. 15, 843-851. (doi:10.1007/s00542-008-0727-8). ... 2007 Polymer carriers for drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 59, 187-206. (doi:10.1016/j.addr.2007.04. ... Another advantage of the current approach is that some drugs or even biomolecules could also be incorporated into the ...http://rsif.royalsocietypublishing.org/content/early/2010/05/20/rsif.2010.0127.focus
Game theory of pre-emptive vaccination before bioterrorism or accidental release of smallpox | Journal of The Royal Society...
2013 Wary of attack with smallpox, U.S. buys up a costly drug. The New York Times. See http://www.nytimes.com/2013/03/13/health ... 2014 CDC: smallpox found in NIH storage room is alive. http://www.cnn.com/2014/07/11/health/smallpoxfound-nih-alive/ (accessed ... stockpiles-smallpox-drug-in-case-of-bioterror-attack.html (accessed 12 August 2014).. ...http://rsif.royalsocietypublishing.org/content/12/107/20141387
Bioinspired interface for nanobiodevices based on phospholipid polymer chemistry | Journal of The Royal Society Interface
Phosphorylcholine-based polymers for stent drug delivery. J. Mater. Sci. Mater. Med. 12, 2001a 865-870. doi:10.1023/A: ... and the kit is used after storage in a refrigerator. The denaturation of the immobilized primary antibodies on the stored plate ... including drugs, may be applied (figure 12). Goto et al. (2008b) used a core with semiconductor nanocrystallite quantum dots ( ...http://rsif.royalsocietypublishing.org/content/6/Suppl_3/S279
Contrasts between organic participation in apatite biomineralization in brachiopod shell and vertebrate bone identified by...
Drug Discov. Today 9, 803-811. doi:10.1016/S1359-6446(04)03222-2 (doi:10.1016/S1359-6446(04)03222-2). ... We have therefore assumed that the SSNMR properties of materials from both species are not sensitive to ethanol storage, and ... that differences observed between the materials from both species are not attributable to differences in storage conditions. ...http://rsif.royalsocietypublishing.org/content/8/55/282
Formalization and reuse of scientific research | Journal of The Royal Society Interface
2010 An ontology for description of drug design investigations. J. Integr. Bioinformat. 7, 126. doi:10.2390/biecoll-jib-2010- ... of science is the comprehensive annotation of all investigations with metadata derived from standard ontologies and storage of ...http://rsif.royalsocietypublishing.org/content/8/63/1440
Biological nano-functionalization of titanium-based biomaterial surfaces: a flexible toolbox | Journal of The Royal Society...
Such drug containers could also be created using self-organized NA polyhedra (Andersen et al. 2008; He et al. 2008). ... Storage under ambient laboratory conditions removed most of the thiol-SAMs within 1 day, whereas phosphonic acid SAMs on Ti ... 1997, 1999) may be used to heighten the number of hybridizable anchor sequences at the surface, or to form 'drug containers' ... In this study all phosphonate- and phosphate-anchored SAMs desorbed to a large extent during storage in TBS within 1 day. ...http://rsif.royalsocietypublishing.org/content/early/2009/11/03/rsif.2009.0418.focus
The effect of nanoscale surface curvature on the oligomerization of surface-bound proteins | Journal of The Royal Society...
2002 Moving smaller in drug discovery and delivery. Nat. Rev. Drug Discov. 1, 77-84. (doi:10.1038/nrd707). ... can facilitate chemical modifications or exchanges and can provide temporary storage or stability for the monomeric state . ... drug delivery [21,22] and the creation of new classes of advanced biomaterials [23-25]. ... Drug Deliv. Rev. 54, 631-651. (doi:10.1016/S0169-409X(02)00044-3). ...http://rsif.royalsocietypublishing.org/content/11/94/20130818
Built for rowing: frog muscle is tuned to limb morphology to power swimming | Journal of The Royal Society Interface
Thus, F-V and drag curves can be superimposed. As the muscle contracts, the plate accelerates until drag balances the limiting ... 2011 Evidence for a vertebrate catapult: elastic energy storage in the plantaris tendon during frog jumping. Biol. Lett. 8, 386 ... Drag torque is. 2.2where CD is the foot drag coefficient (=2 for this study; ), Afin is the fin surface area, ρ is water ... drag owing to muscle shortening rises with GR. Knowing that drag is a major component of the fluid force acting on X. laevis ...http://rsif.royalsocietypublishing.org/content/10/84/20130236
Development of free-energy-based models for chaperonin containing TCP-1 mediated folding of actin | Journal of The Royal...
An interesting peculiarity of working with actin is that it slowly, but spontaneously, unfolds from N to I3 in storage buffers ... Cancer Drug Targets 3 301-323. doi:10.2174/1568009033481877. OpenUrlCrossRefPubMed ... by dialysis from high concentration of denaturant and spontaneously during storage (Kuznetsova et al. 2002). At moderate to ...http://rsif.royalsocietypublishing.org/content/5/29/1391
Effects of carbon nanotubes on plants | Journal of The Royal Society Interface
2010 X-ray absorption spectroscopy (XAS) corroboration of the uptake and storage of CeO2 nanoparticles and assessment of their ... The extraordinary properties of carbon nanotubes (CNTs)  have inspired their use in biosensors , drug delivery vehicles ...http://rsif.royalsocietypublishing.org/content/early/2012/09/11/rsif.2012.0535