Loading...
*  RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in...
At the end of DNA replication, when an ongoing DNA replication fork from one origin encounters an incoming DNA replication fork ... the DNA replication and (B) the DNA replication checkpoint pathway in eukaryotes. DNA replication occurs in two steps that are ... Defects in DNA replication, for instance stalled replication forks, are sensed by the DNA replication checkpoint pathway, which ... DNA replication checkpoint:. Our screens led to the identification of most of the worm homologs of the DNA replication ...
http://www.g3journal.org/content/6/10/3431
*  The DNA replication fork in eukaryotic cells - CSHL Scientific Digital Repository
The process of DNA replication is also coupled to cell-cycle progression and to DNA repair to maintain genome integrity. ... Replication of the two template strands at eukaryotic cell DNA replication forks is a highly coordinated process that ensures ... Waga, S., Stillman, B. (1998) The DNA replication fork in eukaryotic cells. Annual Review of Biochemistry, 67. pp. 721-51. ISSN ... Biochemical studies, principally of plasmid DNAs containing the Simian Virus 40 origin of DNA replication, and yeast genetic ...
http://repository.cshl.edu/25131/
*  Compare the dna replication process in cells with the, Ask an Expert
... compare the dna replication process in cells with the process occurring in the pcr, Hire Biology Expert, Ask Academics Expert, ... 1- Compare the DNA Replication process in cells with the process occurring in the PCR replication. ...
http://www.mywordsolution.com/question/compare-the-dna-replication-process-in-cells-with/928300
*  The DNA polymerase activity of Pol ε holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg...
... rapid and efficient chromosomal DNA replication in Xenopus egg extracts.. Figure 4 DNA replication activity in Pol ε-depleted ... is dispensable for yeast DNA replication, repair, and viability [15, 16, 27], the role of Pol ε during DNA replication has ... and GINS are critical for loading Pol α and Pol ε onto DNA replication origins and for initiating chromosomal DNA replication ... exonucleases of DNA polymerase ε and δ correct base analog induced DNA replication errors on opposite DNA strands in ...
https://bmcbiochem.biomedcentral.com/articles/10.1186/1471-2091-7-21
*  "Checkpoint Regulation of Replication Forks in Response to DNA Damage: " by Nicholas Adrian Willis
Rather than outright halting replication, the S-phase DNA damage checkpoint slows replication in response to DNA damage. This ... slowing of replication fork progression was controversial. Fission yeast slow replication in response to DNA damage utilizing ... The exact role MRN serves to slow replication is obscure due to its many roles in DNA metabolism and checkpoint response to ... Second, this checkpoint slows the progression of the replication forks. Inhibition of origin firing in response to DNA damage ...
https://escholarship.umassmed.edu/gsbs_diss/427/
*  James A. Borowiec
Genotoxic stresses that damage the chromosomal DNA or inhibit the progression of a DNA replication fork can lead to instability ... Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress. ... under conditions of DNA replication stress, RPA phosphorylation by ATR stimulates repair DNA synthesis and prevents ssDNA ... Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery. ...
https://med.nyu.edu/faculty/james-a-borowiec
*  Proliferating cell nuclear antigen
An ectopic domain of DNA replication in the rectum and a slight expansion of DNA replication into the small intestine is ... DNA replication-related element). The examination of a common expression mechanism for DNA replication-related genes, which is ... DNA replication-related element) of DNA replication-related genes, was purified to homogeneity from nuclear extracts of ... Replication factor C (RF-C) is a heteropentameric protein essential for DNA replication and repair. It is a molecular ...
http://www.sdbonline.org/sites/fly/polycomb/pcna3.htm
*  Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p | BMC Biology |...
Hasan S, Hottiger MO: Histone acetyl transferases: a role in DNA repair and DNA replication. J Mol Med. 2002, 80: 463-474. ... and DNA replication. Collectively, our results suggest a previously overlooked role for a specific conserved HAT in DNA ... Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. Proc Natl Acad Sci USA. 1999 ... Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage. Philos Trans R ...
https://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-5-38
*  Adenovirus DNA Replication | SpringerLink
Kelly, T.J., Jr., 1982, Organization and replication of adenovirus DNA, in: Organization and Replication of Viral DNA (A.S. ... Schilling, R., Weingartner, B., and Winnacker, E.-L., 1975, Adenovirus type 2 DNA replication. II. Termini of DNA replication, ... Adenovirus DNA replication: Isolation of a soluble replication system and analysis of the in vitro DNA product, J. Biol. Chem. ... Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA, Proc. Natl. Acad. Sci. U ...
https://link.springer.com/chapter/10.1007/978-1-4684-7935-5_7
*  Guide to DNA Replication
... is the process of unraveling the Double Helix to create a template of matching DNA strands which creates a second set of DNA ... Learn about the DNA replication steps to better understand the process..... DNA Replication Errors DNA replication errors that ... More About Dna Replication. What is DNA Replication? The answer is essential to understanding the basic rules of genetics. An ... DNA replication is an important process resulting in the production of another copy of the DNA strand. Learn about the DNA ...
http://www.brighthub.com/guides/dna-replication.aspx
*  KEGG PATHWAY: DNA replication
Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM ... On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication ... The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA ... DNA replication [ Pathway menu , Organism menu , Pathway entry , Download KGML , Hide description , User data mapping ] A ...
https://www.genome.jp/kegg-bin/show_pathway?map=ko03030&show_description=show
*  3. DNA Replication - Essentials of Molecular Biology [Book]
... of DNA Replication Semi-conservative Mode of Replication/Meselson and Stahl Experiment Enzymes of Replication Prokaryotic DNA ... 3 DNA Replication CONCEPT OUTLINE Introduction Chemistry of DNA Synthesis Modes ...
https://www.oreilly.com/library/view/essentials-of-molecular/9789332501423/xhtml/chapter003.xhtml
*  Proteins Involved in DNA Replication | Ulrich Huebscher | Springer
... teins Involved in DNA Replication' which was held September 19 to 23,1983 at Vitznau, near Lucerne, in Switzerland. The aim of ... different DNA poly- merases, DNA primases, DNA dependent ATPases, helicases, DNA liga- ses, DNA topoisomerases, exo- and ... Initiation of DNA Synthesis on Single-Stranded DNA Templates in Vitro Promoted by the Bacteriophage λ O and P Replication ... Proteins Involved in DNA Replication. Editors. * Ulrich Huebscher Series Title. Advances in Experimental Medicine and Biology. ...
https://www.springer.com/us/book/9781468487329?wt_mc=
*  NIEHS Researchers Identify Enzyme Critical in DNA Replication
Yeast DNA Polymerase & Participates in Leading-Strand DNA Replication. Science, 2007. NIEHS supports research to understand the ... DNA polymerase epsilon has a primary role in replicating the leading strand of DNA. DNA polymerase epsilon was found to be a ... According to Pursell, a researcher in the DNA Replication Fidelity Group at NIEHS and first author on the paper the study's ... The researchers built on fundamental discoveries on the structure and replication of DNA made by Nobel laureates James Watson, ...
https://www.niehs.nih.gov/news/newsroom/releases/2007/july05/index.cfm
*  Why Is DNA Replication Important? | Reference.com
Without replication, each cell lacks enough genetic material... ... DNA replication is important because it creates a second copy ... of DNA that must go into one of the two daughter cells when a cell divides. ... What Is DNA Replication?. A: DNA replication is a process in which DNA is duplicated so that it can be integrated into a new ... How Does DNA Replicate?. A: DNA replication is a process whereby a single DNA molecule produces two identical copies. Each side ...
https://www.reference.com/science/dna-replication-important-accd4bd24c83c572
*  What happens during DNA replication? | Reference.com
... two strands of DNA separate, and each separate strand forms a template to make a new strand. The replication process results in ... What enzymes are involved in DNA replication?. A: Many enzymes are involved in DNA replication, including DNA helicase, DNA ... What is DNA polymerase 1?. A: DNA polymerase I is an enzyme that plays a role in the process of DNA replication, according to ... What best describes the difference between transcription and DNA replication?. * How does an unwound strand of DNA begin to ...
https://www.reference.com/science/happens-during-dna-replication-1774e347f301a6c5
*  Control of DNA Replication by ATR | SpringerLink
DNA replication needs to be carefully controlled to prevent genomic instability and ensure cellular fitness. ATR is a PI3K-like ... Lecona E., Fernández-Capetillo O. (2018) Control of DNA Replication by ATR. In: Pollard J., Curtin N. (eds) Targeting the DNA ... Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444:638-642PubMedCrossRef ... Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. J Biol Chem 279:53353- ...
https://link.springer.com/chapter/10.1007%2F978-3-319-75836-7_3
*  DNA Replication | Wyzant Resources
DNA Replication. Written by tutor Kathie Z.. A copy of DNA must be replicated before the cell can reproduce itself. The DNA ... The original DNA double helix is called the parent strand. Replication is making a copy of DNA which when replicated in a ... This lesson will discuss the first step: DNA Replication.. Deoxyribonucleic Acid (DNA) is the tiny molecule inside every cell ... A sub-unit of the DNA polymerase "proofreads" the new DNA.. *DNA ligase (an enzyme) seals up the fragments into one continuous ...
https://www.wyzant.com/resources/lessons/science/biology/dna-replication
*  DNA replication licensing factor Mcm2 (IPR008045) | InterPro | EMBL-EBI
GO:0006270 DNA replication initiation Molecular Function. GO:0005524 ATP binding GO:0003677 DNA binding GO:0003678 DNA helicase ... DNA replication licensing factor MCM7, IPR008050. In addition to its role in initiation of DNA replication, Mcm2 is able to ... A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.. Proc. Natl. Acad. ... Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.. Cell 139 719-30 2009 ...
http://www.ebi.ac.uk/interpro/entry/IPR008045
*  Optimal Control of Gene Mutation in DNA Replication
... Juanyi Yu, Jr-Shin Li, and Tzyh-Jong Tarn ... M. Zhang, M. X. Cheng, and T. J. Tarn, "A mathematical formulation of DNA computation," IEEE Transactions on Nanobioscience, ... E. C. Friedberg, G. C. Walker, and W. Siede, DNA Repair and Mutagenesis, ASM Press, 1995. ... S. D. McCulloch and T. A. Kunkel, "The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis ...
https://www.hindawi.com/journals/bmri/2012/743172/ref/
*  Cell Division: How DNA Replication Originates | Science
Now, in work done mainly in yeast, researchers are finding that this exquisite control of DNA replication is achieved by a ... but early results suggest that these species use similar proteins for controlling DNA replication. ... As the cells of higher organisms prepare to divide, they face a tremendous logistic problem: How to copy all of their DNA once- ... complex of proteins interacting with specific short DNA sequences. They've also identified several of the proteins that form ...
http://science.sciencemag.org/content/270/5242/1585
*  DNA replication from two different worlds | Science
Replication of the DNA genome is performed by a replisome complex composed of numerous proteins. Cells have duplex DNA genomes ... The replisome functions at a Y junction, or replication fork, and is a complex task because DNA Pols can only extend DNA in a 3 ... two DNA polymerases (Pols) to replicate the two DNA strands, and a primase to form RNA primers that DNA Pols extend. ... Thus, as the helicase unwinds the antiparallel DNA strands, the DNA Pol on one strand (the leading strand) can go in the same ...
http://science.sciencemag.org/content/363/6429/814
*  Frontiers | DNA replication origins in archaea | Microbiology
... known as replication origins), is the key regulatory stage of chromosome replication. Archaea, the third domain of life, use a ... known as replication origins), is the key regulatory stage of chromosome replication. Archaea, the third domain of life, use a ... The basic structure of replication origins is conserved among archaea, typically including an AT-rich unwinding region flanked ... Both the ORB sequence and the adjacent initiator gene are considerably diverse among different replication origins, while in ...
https://www.frontiersin.org/articles/10.3389/fmicb.2014.00179/full
*  DNA Replication and Human Disease
Chapter 19. DNA Damage and Human Disease. Errol C. Friedberg. Chapter 20. DNA Polymerases and the Fidelity of DNA Replication. ... Chapter 10. Temporal Order of DNA Replication. Anne D. Donaldson and Carl L. Schildkraut. Chapter 11. DNA Replication during ... Chapter 8. Termination of DNA Replication. Deepak Bastia and Bidyut K. Mohanty. Chapter 9. DNA Replication and Nuclear ... Chapter 14. Archaeal, Bacterial, and Eukaryal DNA Replication Machines. Stephen D. Bell. PART II: REGULATION OF DNA REPLICATION ...
https://www.cshlpress.com/default.tpl?cart=1531387378329211271&fromlink=T&linkaction=full&linksortby=oop_title&--eqSKUdatarq=549
*  DNA and DNA Replication | Smore Newsletters
DNA and DNA Replication - ' Code of Life' by chris medina , This newsletter was created with Smore, an online tool for creating ... DNA Replication When new DNA needs to be made, replication occurs so that an exact copy of DNA is made from the original strand ... The worksheet DNA-The Double Helix covers basic concepts and ideas about DNA, RNA, and Replication. You need to color the ... 5) Replication Activity Complete the Replication Activity by placing the replication steps in order by first drawing the ...
https://www.smore.com/tg2dd