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*  Application of Genetic Polymorphisms of DNA Repair in The Prediction of Prostate Cancer Susceptibility and Its Clinical Outcome...
DNA repair plays a key role in carcinogenesis through the removal and repair of DNA damage induced by endogenous and ... Common polymorphisms in DNA repair gene may alter protein function and individual's capacity to repair damaged DNA, hence, ... The DNA repair system included four pathways: 1) Base Excision Repair (BER), 2) Nucleotide Excision Repair (NER), 3) Mismatch ... XRCC1 is involved in DNA repair in the base excision pathway, the hOGG1 gene encodes a DNA glycosylase /apurinic-apyrimidinic ...
https://clinicaltrials.gov/ct2/show/NCT00167024?term=prostate+cancer+screening&recr=Open&rank=20
*  DNA repair synthesis in human heterokaryons. III. The rapid and slow complementing varieties of xeroderma pigmentosum | Journal...
DNA repair synthesis in human heterokaryons. III. The rapid and slow complementing varieties of xeroderma pigmentosum ... Patients with Xeroderma pigmentosum and defective DNA excision repair can be distinguished as a rapid (r-XP) and slow (s-XP) ... DNA repair synthesis in human heterokaryons. III. The rapid and slow complementing varieties of xeroderma pigmentosum ... DNA repair synthesis in human heterokaryons. III. The rapid and slow complementing varieties of xeroderma pigmentosum ...
http://jcs.biologists.org/content/20/1/207
*  "Transcription restores DNA repair to heterochromatin, determining regi" by Christina L. Zheng, Gary M. Fudem et al.
XPC(-/-) cells lack global genome nucleotide excision repair (GG-NER), thus establishing differential access of DNA repair ... We model this relationship among transcription, chromatin state, and DNA repair, revealing a new, personalized determinant of ... appears to reduce mutation prevalence specifically by relieving the constraints imposed by chromatin structure on DNA repair. ... Carcinoma, Squamous Cell; DNA Packaging; DNA Repair; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genome, ...
https://escholarship.umassmed.edu/oapubs/2581/
*  Characterization of cellular DNA repair capacity by molecular and cytogenetic approaches: suitability as intermediate phenotype...
DNA repair [MeSH]. Neoplasms [MeSH]. Sister chromatid exchange [MeSH]. Schlagwörter DNA repair capacity; Environmental ... The purpose of this study was to elucidate if the cellular DNA repair capacity, genotypes of DNA repair genes and the ... DNA repair end points are largely independent and can be used to characterize different aspects of the cellular DNA repair ... DNA repair assays were performed in parallel on peripheral blood samples of the probands: the baseline and the radiation ...
https://oparu.uni-ulm.de/xmlui/handle/123456789/2284
*  Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC
... Journal. Journal of Cell Science. ... To investigate how the nucleotide excision repair initiator XPC locates DNA damage in mammalian cell nuclei we analyzed the ... DNA-damaging agents retard the mobility of XPC, and UV damage has the most pronounced effect on the mobility of XPC-GFP. XPC ... To avoid excessive DNA probing by the low specificity of the protein, the steady-state level in the nucleus is controlled by ...
http://dare.uva.nl/search?metis.record.id=298187
*  Download A Histone H3K36 Chromatin Switch Coordinates Dna Double Strand Break Repair Pathway Choice 2014
However so as it is, in iterative download A histone H3K36 chromatin switch coordinates DNA double strand break repair pathway ... in download A histone H3K36 chromatin switch coordinates DNA double strand break repair pathway may bring one of the happiest ... KIRRALIE SMITH: A download A histone H3K36 chromatin switch coordinates DNA double strand break repair pathway choice of the ... Some problems in our download A histone H3K36 chromatin switch coordinates DNA double strand break repair pathway do a ...
http://bobcatsworld.com/library/download-A-histone-H3K36-chromatin-switch-coordinates-DNA-double-strand-break-repair-pathway-choice-2014.php
*  Category:DNA repair - Wikimedia Commons
DNA repair (en-ca); DNA onarımı (tr); DNA修復 (zh-hk); DNA repair (en); การซ่อมแซมดีเอ็นเอ (th); Oprava DNA (sk); Pemulihan DNA ( ... DNA-Reparatur (de-ch); DNA-Reparatur (de); Reparazion del DNA (lmo); DNA repair (en-gb); ԴՆԹ-ի ռեպարացիա (hy); ДНК корекция (bg ... DNA repair (tl); Reparo de ADN (pt-br); DNA修复 (zh-sg); Reparasi DNA (id); DNA-reparasjon (nn); DNA-reparasjon (nb); Popravka ... DNA:n korjaus (fi); SOS-жауап (kk); riparo de DNA (eo); Oprava DNA (cs); டி என் ஏ சீராக்கம் (ta); riparazione del
https://commons.wikimedia.org/wiki/Category:DNA_repair
*  Mechanisms of DNA Repair
There are two general classes of DNA repair; the direct reversal of the chemical process generating the damage and the ... Sunderland (MA): Sinauer Associates: DNA Repair.. *Eker, A.P. et al. 2009. DNA repair in mammalian cells: Direct DNA damage ... The direct reversal DNA repair mechanism. Direct reversal of DNA damage is a mechanism of repair that does not require a ... DNA double strand break repair. The repair of damage to both DNA strands is particularly important in maintaining genomic ...
https://www.news-medical.net/life-sciences/Mechanisms-of-DNA-Repair.aspx
*  DNA Repair & Nucleic Acid Enzymology Group
... and its biological roles in base excision DNA repair. This DNA repair pathway protects cells against endogenous DNA lesion ... the study of gap-filling DNA synthesis in DNA repair. To define the biological role of DNA polymerase beta, the group and ... DNA Repair & Nucleic Acid Enzymology Group. Mechanisms of DNA Synthesis. Samuel H. Wilson, M.D. Principal Investigator Tel 984- ... the study of gap-filling DNA synthesis in DNA repair ("/Rhythmyx/assembler/render?sys_contentid=53298&sys_revision=1&sys_ ...
https://www.niehs.nih.gov/research/atniehs/labs/gisbl/pi/dnarna/
*  DNA Repair
... provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair provides a forum for the comprehensive coverage of DNA repair and cellular responses to DNA damage. The journal ... DNA Repair sponsors GRC DNA Damage, Mutation & Cancer 2018 * 3rd DNA Replication/Repair Structures and Cancer - Fusion ...
https://www.journals.elsevier.com/dna-repair
*  Vitamin D and DNA repair
... directly regulates the expression of a variety of genes whose protein products are involved in DNA damage repair. ... scientists have identified at least five genes that code for DNA repair proteins, whose only job is to fix your DNA when it is ... DNA repair usually works by correcting one strand to match another template strand. It would not fix an inherited mutation ... 5 Responses to Vitamin D and DNA repair. *. PeterVermont. January 17, 2012 at 5:11 am ...
https://www.vitamindcouncil.org/vitamin-d-and-dna-repair/
*  Proteomics identifies DNA repair toolbox
DNA »DNA repair »Max Planck Institute »Max-Planck-Institut »Proteomics »damaged DNA »daughter cells »genomic »machinery » ... Further reports about: , DNA , DNA repair , Max Planck Institute , Max-Planck-Institut , Proteomics , damaged DNA , daughter ... Proteomics identifies DNA repair toolbox. 04.05.2015. Various repair mechanisms help our cells to revert damage to their DNA. ... DNA repair requires many factors, but so far there have not been comprehensive analyses of the intricate pathways involved. ...
https://www.innovations-report.com/html/reports/life-sciences/proteomics-identifies-dna-repair-toolbox.html
*  Electrically monitoring DNA repair by photolyase | PNAS
DNA repair can, moreover, be monitored electrically. Exposure of photolyase on T,,T-damaged DNA films to near-UV/blue light ... DNA-modified gold surfaces have recently been used in the study of DNA repair proteins possessing [4Fe-4S] clusters, such as ... T,,T Repair Probed Electrochemically. Photoactivation of photolyase bound to DNA containing T,,T lesions leads to the repair of ... 6). The surface DNA has the same retention time as undamaged DNA, indicating that the T,,T damage has been repaired on the ...
http://www.pnas.org/content/102/31/10788
*  DNA Repair and Simple Recombination | SpringerLink
... for repairing any damage). Nevertheless, most organisms can undergo some sort of... ... Birge E.A. (1994) DNA Repair and Simple Recombination. In: Bacterial and Bacteriophage Genetics. Springer, New York, NY. * DOI ... and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proceedings of the National Academy of Sciences ... Madiraju, M.V.V.S., Clark, A.J. (1992). Evidence for ATP binding and double-stranded DNA binding by Escherichia coli RecF ...
https://link.springer.com/chapter/10.1007/978-1-4757-2328-1_5
*  How DNA Repair Helps Prevent Cancer - Redorbit
Feig studies the proteins MutS and MSH2-MSH6, which recognize defective DNA and initiate DNA repair. Natural DNA repair occurs ... "DNA damage occurs frequently and if you couldn't repair your DNA, then you won't live for very long." This is because damaged ... "We believe that DNA bending facilitates the initial recognition of the mismatched base for repair," Feig said. "Normal DNA is ... In these cases, cancer is not a result of damaged DNA, but occurs because of a problem in the DNA repair mechanism itself. ...
http://www.redorbit.com/news/health/1112926275/how-dna-repair-helps-prevent-cancer/
*  ORMUS, DNA Repair and Health
In other words, it looks like Cisplatin can both damage and repair DNA. Unfortunately Cisplatin does not repair the damaged DNA ... healthy DNA to the damaged DNA in the cancer cells. We believe that they also mediate the repair of the DNA like the Cisplatin ... Likewise, whenever the body needs to repair a cellular defect, the DNA must unwind so repair enzymes can snip off the defective ... physical DNA the ORMUS elements can facilitate the repair of the DNA to this healthy template. Let s examine these concepts. ...
https://www.bibliotecapleyades.net/ciencia/esp_ciencia_oro13.htm
*  Nobel shows link between DNA repair, diseases
An expert in DNA repair says the amount of damage caused to our DNA each day is astounding - an estimated 50,000 lesions per ... Nobel shows link between DNA repair, diseases An expert in DNA repair says the amount of damage caused to our DNA each day is ... Nobel shows link between DNA repair, diseases An expert in DNA repair says the amount of damage caused to our DNA each day is ... STOCKHOLM (AP) - An expert in DNA repair says the amount of damage caused to our DNA each day is astounding - an estimated ...
https://www.elpasotimes.com/story/news/national/2015/10/07/nobel-shows-link-between-dna-repair-diseases/73508798/?from=new-cookie
*  DNA repair protein XRCC4 (IPR010585) | InterPro | EMBL-EBI
... the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ... This entry represents the DNA double-strand break repair and V(D)J recombination protein XRCC4, which is found in certain ... XRCC4 binds to DNA, and to DNA ligase IV (LIG4) to form the LIG4-XRCC4 complex [PMID: 11029705]. The LIG4-XRCC4 complex is ... Requirement for XRCC4 and DNA ligase IV in alignment-based gap filling for nonhomologous DNA end joining in vitro.. Cancer Res. ...
http://www.ebi.ac.uk/interpro/entry/IPR010585
*  Bcl2 Blocks DNA Repair | Science Signaling
report that a nuclear function of Bcl2 appears to be inhibition of the DNA repair enzyme APE1, which mediates the repair of ... Thus, inhibition of DNA repair may contribute to the oncogenic properties of Bcl2. ... In the nucleus, Bcl2 interacts with apurinic/apyrimidinic endonuclease 1 (APE1) to inhibit DNA repair. ... In the nucleus, Bcl2 interacts with apurinic/apyrimidinic endonuclease 1 (APE1) to inhibit DNA repair. ...
http://stke.sciencemag.org/content/1/15/ec134
*  Properties of DNA Repair Enzymes | NEB
Properties of DNA Repair Enzymes Enzyme Substrate Cleavage site Termini created from cleavage 5' terminus 3' terminus APE 1 AP ... NEB carries an array of reliable DNA repair enzymes for use in multiple applications. ... Properties of DNA Repair Enzymes Properties of DNA Repair Enzymes. NEB carries an array of reliable DNA repair enzymes for use ... DNA Repair Glycosylases on Various Damaged Bases. Double-stranded DNA Oligos (34-mers). ...
https://www.neb.com/tools-and-resources/selection-charts/dna-repair-enzymes
*  Snapshot of DNA repair
... a crucial interaction for DNA repair, to find a unique interaction. ... The DNA is protected, however, by DNA repair machinery. A new study from scientists at Osaka University and The University of ... Snapshot of DNA repair. (Nanowerk News) Osaka University scientists, in collaboration with The University of Tokyo, describe ... To activate the DNA repair machinery, DSBs stimulate ubiquitylation. RNF168 binds to polyubiquitylated proteins and accumulates ...
https://www.nanowerk.com/news2/biotech/newsid=49122.php
*  DNA Repair: Novus Biologicals
In human cells, normal metabolic activities and environmental factors cause DNA damage. ... DNA repair refers to a collection of processes by which cells identify and correct damaged DNA. ... Antibodies Used in DNA Repair Antibodies are a common tool in DNA repair, with hundreds of subgroups that mark specific ... The rate of DNA repair is dependent of many factors, including cell type, cell age and the extracellular environment. The DNA ...
https://www.novusbio.com/research-areas/cancer/dna-repair.html
*  DNA Repair - Molecular Biology of the Cell - NCBI Bookshelf
... in DNA are temporary because they are immediately corrected by a set of processes that are collectively called DNA repair. Of ... but also mechanisms for repairing the many accidental lesions that occur continually in DNA. Most such spontaneous changes ... only a few accumulate as mutations in the DNA sequence. We now know that fewer than one in 1000 accidental base changes in DNA ... the rest are eliminated with remarkable efficiency by DNA repair. ... the thousands of random changes created every day in the DNA of ...
https://www.ncbi.nlm.nih.gov/books/NBK26879/
*  Phys.org - dna repair
DNA repair. DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules ... or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states:. The DNA repair ... Snapshot of DNA repair. DNA is like the computer code of the body, and it must be preserved for our bodies to survive. Yet, as ... Consequently, the DNA repair process is constantly active as it responds to damage in the DNA structure. ...
https://phys.org/tags/dna+repair/
*  Breaking down the mysteries of DNA repair | BrandeisNOW
In this process, the cell attempts to repair damaged DNA by locating and copying a donor sequence, a nearly identical copy that ... Breaking down the mysteries of DNA repair Biologist James Haber's latest findings offer new insights into what goes wrong in ... For nearly three decades, Abraham and Etta Goodman Professor of Biology James Haber has studied DNA repair, the processes ... They determined the minimum amount of homologous DNA sequence necessary for a specific repair process known as homologous ...
https://www.brandeis.edu/now/2017/February/dna-repair-haber.html