DNA DamageDNA RepairComet AssayAtaxia Telangiectasia Mutated ProteinsCell Cycle ProteinsUltraviolet RaysDeoxyguanosineCheckpoint Kinase 2Tumor Suppressor Protein p53DNA-Binding ProteinsDNA Breaks, Double-StrandedProtein-Serine-Threonine KinasesOxidative StressCell CycleTumor Suppressor ProteinsGamma RaysApoptosisDNAMethyl MethanesulfonateHistonesMutagensNuclear ProteinsGenomic InstabilityG2 PhaseDNA ReplicationMutationPhosphorylationCell Line, TumorDNA Repair EnzymesDose-Response Relationship, RadiationDNA AdductsReactive Oxygen SpeciesCell SurvivalCell LineHydrogen PeroxideDNA BreaksRadiation ToleranceProtein KinasesPoly(ADP-ribose) PolymerasesGenes, cdcCell Cycle CheckpointsDNA Breaks, Single-StrandedSignal TransductionRad51 RecombinaseDNA GlycosylasesHeLa CellsS PhaseSaccharomyces cerevisiae ProteinsBRCA1 ProteinCells, CulturedFibroblastsMitosisCell AgingMicronucleus TestsSaccharomyces cerevisiaeCell NucleusHydroxyureaAntioxidantsDNA-Activated Protein KinaseG2 Phase Cell Cycle CheckpointsIntracellular Signaling Peptides and ProteinsChromatinAlkylating AgentsX-RaysTime FactorsReplication Protein ARecombinational DNA RepairModels, BiologicalProtein BindingDNA HelicasesOxidation-ReductionPoly Adenosine Diphosphate RiboseCell DeathRNA, Small InterferingMolecular Sequence DataSOS Response (Genetics)Proto-Oncogene Proteins c-mdm2Recombination, GeneticPyrimidine DimersDNA-Formamidopyrimidine GlycosylaseMitomycinHCT116 CellsMicronuclei, Chromosome-DefectiveUbiquitinationCyclin-Dependent Kinase Inhibitor p21TelomereNucleic Acid Synthesis InhibitorsDNA End-Joining RepairBlotting, WesternMutagenicity TestsGuanineDose-Response Relationship, DrugXeroderma Pigmentosum Group A ProteinLymphocytesDNA, FungalAtaxia TelangiectasiaOxidantsEndodeoxyribonucleasescdc25 PhosphatasesProliferating Cell Nuclear Antigen