Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC  Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC
... in the absence of DNA damage. DNA-damaging agents retard the mobility of XPC, and UV damage has the most pronounced effect on ... Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC. Journal. Journal of Cell Science. ... To investigate how the nucleotide excision repair initiator XPC locates DNA damage in mammalian cell nuclei we analyzed the ... To avoid excessive DNA probing by the low specificity of the protein, the steady-state level in the nucleus is controlled by ...
more infohttp://dare.uva.nl/search?metis.record.id=298187
Effects of proton beams from the folded tandem ion accelerator on DNA damage in mouse leukocytes using the comet assay on...  Effects of proton beams from the folded tandem ion accelerator on DNA damage in mouse leukocytes using the comet assay on...
Single cell gel electrophoresis or the comet assay is a sensitive technique to quantify different types of DNA damage, e.g... ... Article Effects of proton beams from the folded tandem ion accelerator on DNA damage in mouse leukocytes using the comet assay ... No comments were found for Effects of proton beams from the folded tandem ion accelerator on DNA damage in mouse leukocytes ... Effects of proton beams from the folded tandem ion accelerator on DNA damage in mouse leukocytes using the comet assay. 0 ...
more infohttps://www.environmental-expert.com/articles/effects-of-proton-beams-from-the-folded-tandem-ion-accelerator-on-dna-damage-in-mouse-leukocytes-usi-84376
Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC | Journal of Cell Science  Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC | Journal of Cell Science
Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC ... Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC ... Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC ... Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC ...
more infohttp://jcs.biologists.org/content/121/23/3991
The E3 Ubiquitin Ligase EDD Regulates S-Phase and G(2)/M DNA Damage Checkpoints  The E3 Ubiquitin Ligase EDD Regulates S-Phase and G(2)/M DNA Damage Checkpoints
S and intra S phase DNA damage checkpoint activation and for the maintenance of G(2)/M arrest after double strand DNA breaks. ... S and intra S phase DNA damage checkpoint activation and for the maintenance of G(2)/M arrest after double strand DNA breaks. ... ligase EDD have been observed in a number of carcinomas and we recently reported that EDD modulates activity of the DNA damage ... ligase EDD have been observed in a number of carcinomas and we recently reported that EDD modulates activity of the DNA damage ...
more infohttps://www.garvan.org.au/research/publications/2251
Leicester Research Archive: Assessment of Phytochemicals in Preventing Oxidatively Damaged DNA in Bladder Cancer  Leicester Research Archive: Assessment of Phytochemicals in Preventing Oxidatively Damaged DNA in Bladder Cancer
Oxidatively damaged DNA is thought to be important in both the initiation and development of bladder carcinoma. Phytochemical ... Our studies demonstrated that mirtoselect was potent enough to reduce levels of exogenously-induced oxidatively damaged DNA in ... repair endonucleases that recognise specific types of damage in the DNA and converts these lesions into additional DNA breaks ... on the level of endogenous and induced oxidatively damaged DNA in bladder cancer cells, as assessed by the Comet assay. The ...
more infohttps://lra.le.ac.uk/handle/2381/10158
Checkpoint Regulation of Replication Forks in Response to DNA Damage:  by Nicholas Adrian Willis  "Checkpoint Regulation of Replication Forks in Response to DNA Damage: " by Nicholas Adrian Willis
Rather than outright halting replication, the S-phase DNA damage checkpoint slows replication in response to DNA damage. This ... cellular processes in the presence of DNA damage preventing cell cycle transitions until replication is completed or DNA damage ... Inhibition of origin firing in response to DNA damage is well established, however when this thesis work began, slowing of ... Fission yeast slow replication in response to DNA damage utilizing an evolutionarily conserved kinase cascade. Slowing requires ...
more infohttps://escholarship.umassmed.edu/gsbs_diss/427/
DNA damage | Open Library  DNA damage | Open Library
DNA damage, DNA repair, DNA Repair, Congresses, DNA Damage ... DNA damage by Biochemical Society (Great Britain). Symposium; 1 ... DNA damage from causes to cures organised and edited by Richard P. Bowater, Rhonda H. Borts and Malcolm F. White Published 2009 ... Based on papers presented at the 2008 Biochemical Society Annual Symposium entitled "DNA damage: from causes to cures", held at ... Citation ,publisher = Portland Press ,ol = 24382592M ,isbn = 9781855781733 ,publication-place = London ,title = DNA damage , ...
more infohttps://openlibrary.org/works/OL15412262W/DNA_damage
Editorial: DNA damage & immunity.  - PubMed - NCBI  Editorial: DNA damage & immunity. - PubMed - NCBI
Editorial: DNA damage & immunity.. Garinis GA1, Schwer B2, Schumacher B3. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/28445698
DNA Damage and Carcinogenesis | SpringerLink  DNA Damage and Carcinogenesis | SpringerLink
They indicate that damage to DNA can lead to cancer and hence one should be... ... Setlow R.B. (1981) DNA Damage and Carcinogenesis. In: Seeberg E., Kleppe K. (eds) Chromosome Damage and Repair. NATO Advanced ... They indicate that damage to DNA can lead to cancer and hence one should be concerned about environmental agents that react ... Nevertheless, there are arguments against this point of view (1) and, even if damage to DNA is the important element in cancer ...
more infohttps://link.springer.com/chapter/10.1007/978-1-4684-7956-0_70
DNA Damage, Neurodegeneration, and Synaptic Plasticity  DNA Damage, Neurodegeneration, and Synaptic Plasticity
... Guest Editors: Daniela Merlo, Inmaculada C. Ibañez, Rosanna Parlato, ... DNA Damage, Neurodegeneration, and Synaptic Plasticity, Daniela Merlo, Inmaculada Cuchillo-Ibañez, Rosanna Parlato, and Gerhard ... The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease, Laura Narciso, Eleonora Parlanti, Mauro Racaniello, ...
more infohttps://www.hindawi.com/journals/np/si/386321/
Cell umbrella protects stem cells from DNA damage  Cell umbrella protects stem cells from DNA damage
... which could provide protection from other forms of DNA damage.. Fish have evolved the ability to mitigate UV-induced DNA damage ... Cell umbrella protects stem cells from DNA damage. Adult stem cells reside in niches that maintain, regulate and protect them. ... reside in specialized microenvironments called niches that help to protect them from DNA damage. a, Kapp et al.1 have described ... and showed that UV radiation caused higher levels of DNA damage in these fish than in controls, as well as an increase in HSPC ...
more infohttps://www.nature.com/articles/d41586-018-05166-1?error=cookies_not_supported&code=c98a06ff-2b0f-4bd7-800f-77905e2c8500
Signalling DNA Damage | IntechOpen  Signalling DNA Damage | IntechOpen
Signalling DNA Damage. By Andres Joaquin Lopez-Contreras and Oscar Fernandez-Capetillo ... Andres Joaquin Lopez-Contreras and Oscar Fernandez-Capetillo (September 6th 2012). Signalling DNA Damage, Protein ... Andres Joaquin Lopez-Contreras and Oscar Fernandez-Capetillo (September 6th 2012). Signalling DNA Damage, Protein ... www.intechopen.com/embed/protein-phosphorylation-in-human-health/signalling-dna-damage' /,. Embed this code snippet in the HTML ...
more infohttps://www.intechopen.com/books/protein-phosphorylation-in-human-health/signalling-dna-damage/
DNA damage repair: anytime, anywhere?  - PubMed - NCBI  DNA damage repair: anytime, anywhere? - PubMed - NCBI
Regulation of the DNA damage response is tightly connected to transcription and replication. These DNA transacting processes ... DNA damage repair: anytime, anywhere?. Essers J1, Vermeulen W, Houtsmuller AB. ... Currently, quantitative live cell imaging techniques combined with methods to induce local DNA damage in a small region of the ... However, unlike replication and transcription, DNA repair systems may be required anywhere, and at any time, whenever DNA ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/16631362
DNA Damage & Repair - QIAGEN  DNA Damage & Repair - QIAGEN
DNA Damage Signaling Pathway RT2 Profiler PCR Array The Rat DNA Damage Signaling RT² Profiler PCR Array profiles the expression ... DNA Damage Signaling Pathway RT2 Profiler PCR Array The Human DNA Damage Signaling RT² Profiler PCR Array profiles the ... DNA Damage Signaling Pathway RT2 Profiler PCR Array The Mouse DNA Damage Signaling RT² Profiler PCR Array profiles the ... DNA Damage Signaling Pathway EpiTect ChIP qPCR Array The Human DNA Damage Signaling Pathway EpiTect ChIP qPCR Array profiles ...
more infohttps://www.qiagen.com/mx/shop/genes-and-pathways/complete-biology-list/dna-damage-and-repair/
DNA Damage & Repair - QIAGEN  DNA Damage & Repair - QIAGEN
DNA Damage Signaling Pathway RT2 Profiler PCR Array The Rat DNA Damage Signaling RT² Profiler PCR Array profiles the expression ... DNA Damage Signaling Pathway RT2 Profiler PCR Array The Human DNA Damage Signaling RT² Profiler PCR Array profiles the ... DNA Damage Signaling Pathway RT2 Profiler PCR Array The Mouse DNA Damage Signaling RT² Profiler PCR Array profiles the ... DNA Damage Signaling Pathway EpiTect ChIP qPCR Array The Human DNA Damage Signaling Pathway EpiTect ChIP qPCR Array profiles ...
more infohttps://www.qiagen.com/se/shop/genes-and-pathways/complete-biology-list/dna-damage-and-repair/
Polyomavirus interaction with the DNA damage response | SpringerLink  Polyomavirus interaction with the DNA damage response | SpringerLink
Host DNA damage response factors localize to merkel cell polyomavirus DNA replication sites to support efficient viral DNA ... In response to any source of DNA damage, cells must initiate an effective DNA damage response (DDR) to maintain genomic ... Viral DNA replication-dependent DNA damage response activation during bk polyomavirus infection. J Virol, 89: 5032-5039. ... The DNA damage response: Making it safe to play with knives. Mol Cell, 40: 179-204.CrossRefPubMedCentralPubMedGoogle Scholar ...
more infohttps://link.springer.com/article/10.1007/s12250-015-3583-6
Cellular Responses to Cisplatin-Induced DNA Damage  Cellular Responses to Cisplatin-Induced DNA Damage
... and functional aspects of DNA and RNA research. ... involves DNA damage and p53 is also involved in DNA damage ... The DNA damage response is transduced mainly via p53 and c-Abl. Cisplatin-induced DNA damage activates p53, leading to the ... it stalls cell proliferation by inhibiting DNA synthesis, followed by activation of DNA damage response. [. 5. ]. Cisplatin-DNA ... suggesting alternate pathways of sensing cisplatin-induced DNA damage.. 6.2. c-Abl and Cisplatin-Induced DNA Damage Response. ...
more infohttps://www.hindawi.com/journals/jna/2010/201367/
DNA Damage and Aging | Science Signaling  DNA Damage and Aging | Science Signaling
The causal role of oxidative DNA damage in aging is strongly supported in a study by de Boer et al. (see the Perspective by ... The authors propose that the aging phenotype in the TTD mice is caused by unrepaired DNA damage that compromises transcription ... showed greatly accelerated aging that correlated with an increased cellular sensitivity to oxidative DNA damage. ... A popular theory postulates that aging is triggered by cellular accumulation of oxidative damage. ...
more infohttps://stke.sciencemag.org/content/2002/133/TW181
Dealing with DNA Damage | Science Signaling  Dealing with DNA Damage | Science Signaling
provide a mechanism through which cells with genomic damage may switch between these alternative fates. DNA damage activates a ... For an organism to remain healthy, cells with damaged DNA must either pause in the cell cycle for a repair job or succumb to ... The death of cells with damaged DNA results in part from altered localization of a transcription factor, triggered by a cell ... The death of cells with damaged DNA results in part from altered localization of a transcription factor, triggered by a cell ...
more infohttp://stke.sciencemag.org/content/2006/357/tw359
Underground air might cause DNA damage  Underground air might cause DNA damage
Particularly damaging to our cellular DNA are the particles from the underground system in Stockholm, Sweden, according to a ... Underground air might cause DNA damage. 15.12.2006. Our everyday environments are full of airborne particles that are harmful ... Free radicals are highly reactive molecules that can prove harmful to the cell's DNA; although such damage can often be ... The damage is caused when these particles enter the body and form free radicals in the body's cells. ...
more infohttp://www.innovations-report.com/html/reports/medicine-health/report-76017.html