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*  "Change-point analysis of paired allele-specific copy number variation " by Yinglei Lai
... us to explore two types of genomic information including chromosomal genotype variations as well as DNA copy number variations ... The recent genome-wide allele-specific copy number variation data enable ... us to explore two types of genomic information including chromosomal genotype variations as well as DNA copy number variations ... Lai, Y. (2012). Change-point analysis of paired allele-specific copy number variation data. Journal of Computational Biology, ...
https://hsrc.himmelfarb.gwu.edu/biostatscenter_facpubs/36/
*  Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for...
Origins and functional impact of copy number variation in the human genome. Nature. 2010;464:704-712. doi: 10.1038/nature08516. ... to quantify the number of DNA copies. ΔΔCt were calculated with the ALB and TNNI3K genes for normalization. The validated CNVs ... De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot. Nat Genet. 2009;41:931-935. ... Contribution of rare copy number variants to isolated human malformations. PLoS One. 2012;7:e45530. doi: 10.1371/journal.pone. ...
http://circgenetics.ahajournals.org/content/9/1/86
*  Methods and strategies for analyzing copy number variation using DNA microarrays. - PubMed - NCBI
The association of DNA copy-number variation (CNV) with specific gene function and human disease has been long known, but the ... Methods and strategies for analyzing copy number variation using DNA microarrays.. Carter NP1. ... The red horizontal lines indicate regions of similar copy number. Numbers 1 and 2 indicate clusters of probes (CNVs) with low ... Copy-number ratio is graphed on the y axis. (a) High-resolution NimbleGen oligonucleotide array. ...
https://www.ncbi.nlm.nih.gov/pubmed/17597776?dopt=Abstract
*  Methods and strategies for analyzing copy number variation using DNA microarrays
The association of DNA copy-number variation (CNV) with specific gene function and human disease has been long known, but the ... Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays. Genome Res. 2006;16:1575- ... High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat. Genet. 1998; ... Methods and strategies for analyzing copy number variation using DNA microarrays. Nigel P Carter ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2697494/
*  Frontiers | Copy Number Variation of Mitochondrial DNA Genes in Pneumocystis jirovecii According to the Fungal Load in BAL...
... in which copy number of mitochondrial genes was significantly different among them. More importantly, copy number of mtLSU rRNA ... in which copy number of mitochondrial genes was significantly different among them. More importantly, copy number of mtLSU rRNA ... 37 copies) than NAD1 (23 copies), mtLSU rRNA (15 copies) and CYTB (6 copies) genes compared to nuclear genome. Hierarchical ... 37 copies) than NAD1 (23 copies), mtLSU rRNA (15 copies) and CYTB (6 copies) genes compared to nuclear genome. Hierarchical ...
https://www.frontiersin.org/articles/10.3389/fmicb.2016.01413/full
*  Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. - Full Text...
Genetic: Genetic study of DNA copies Gene expression profiling, DNA copy number variation ... Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From MGUS and SMM. (GENOMGUS). ... The purpose of this study is to describe DNA copy number variations and gene expression profiles of bone marrow plasma cells of ... Large Scale Study of DNA Copy Numbers Variations and Gene Expression Profile of Bone Marrow Plasma Cells From Monoclonal ...
https://clinicaltrials.gov/ct2/show/NCT01079429
*  DNA Copy Number Variations | Profiles RNS
"DNA Copy Number Variations" by people in UAMS Profiles by year, and whether "DNA Copy Number Variations" was a major or minor ... DNA Copy Number Variations*DNA Copy Number Variations. *DNA Copy Number Variation ... "DNA Copy Number Variations" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH ( ... Stretches of genomic DNA that exist in different multiples between individuals. Many copy number variations have been ...
https://uams-triprofiles.uams.edu/profiles/display/117558
*  A Statistical Change Point Model Approach for the Detection of DNA Copy Number Variations in Array CGH Data - Semantic Scholar
We derive an approximate p-value for the test statistic and also give the estimate of the locus of the DNA copy number change. ... identifying statistically significant DNA copy number changes in aCGH data is challenging. We propose a novel approach that ... These simulation results show that the approach is effective in identifying copy number changes. The approach is also tested on ... provides a high-resolution and high-throughput technique for screening of copy number variations (CNVs) within the entire ...
https://www.semanticscholar.org/paper/A-Statistical-Change-Point-Model-Approach-for-the-Chen-Wang/4892aeaa695c032ed4a39c814be109c9d31095cb
*  Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data | BMC...
By estimating DNA origin firing time and fork moving velocity from genome-wide time-course S-phase copy number variation data, ... In this paper, we develop a probabilistic model - Spanned Firing Time Model (SFTM) to characterize DNA replication process. The ... Recent genome-wide study of DNA replication approximated origin firing efficiency by indirectly measuring other quantities ... Direct measurement of origin firing efficiency by techniques such as DNA combing are time-consuming and lack the ability to ...
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-247
*  Mitochondrial DNA Copy Number and Genetic Variation in Coronary Heart Disease - Dan Arking
Mitochondrial DNA Copy Number and Genetic Variation in Coronary Heart Disease Arking, Dan E. Johns Hopkins University, ... Mitochondrial DNA Copy Number and Genetic Variation in Coronary Heart Disease. Arking, Dan E. / Johns Hopkins University. ... Mitochondrial DNA Copy Number and Genetic Variation in Coronary Heart Disease. Arking, Dan E. / Johns Hopkins University. ... Mitochondrial DNA Copy Number and Genetic Variation in Coronary Heart Disease. Arking, Dan E. / Johns Hopkins University. $ ...
http://grantome.com/grant/NIH/R01-HL131573-03
*  Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data |...
Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data. ... Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data. BMC ...
http://scholarbank.nus.edu.sg/handle/10635/28584
*  Germline DNA copy number variation in familial and early-onset breast cancer | Breast Cancer Research | Full Text
Germline DNA copy number variation (CNV) has recently been implicated in predisposition to cancers such as neuroblastomas as ... Recent studies have highlighted DNA copy number variation (CNV) as the most prevalent type of structural variation in the human ... containing the selected copy number variation (CNV) (left) and the copy number of the corresponding sequences assessed by ... Germline DNA copy number variation (CNV) has recently been implicated in predisposition to cancers such as neuroblastomas as ...
https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3109
*  Identification of genes with a correlation between copy number and expression in gastric cancer
0.5, maximum number of aberration regions. =. 10,000. The log2 ratio of 0.5 corresponds to a 1.4-fold variation in the DNA copy ... Table S4. Copy number associated gene expression changes. Pearson correlation coefficients between DNA copy number aberrations ... DNA copy number variations in gastric cancer. The 27 pairs of gastric samples were analyzed by aCGH as shown in Additional file ... 2B). DNA copy number variation profiling of N0 and N1-3 stages also revealed 18 significantly altered genomic regions (1q32.2, ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC3441862/
*  Submegabase copy number variations arise during cerebral cortical neurogenesis as revealed by single-cell whole-genome...
2018) Increased DNA copy number variation mosaicism in elderly human brain. Neural Plast 2018:2406170. ... Reports of copy number variations (CNVs) within single human brain cells have been limited to megabase-scale alterations in ... Somatic copy number variations (CNVs) exist in the brain, but their genesis, prevalence, forms, and biological impact remain ... 2014) Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain. Cell Rep 8:1280- ...
http://www.pnas.org/content/115/42/10804
*  Lea Grinberg, MD, PhD | Memory and Aging Center
Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene.. ... Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain.. Neural plasticity ... Do Copy Number Changes in CACNA2D2, CACNA2D3, and CACNA1D Constitute a Predisposing Risk Factor for Alzheimer's Disease?. ... Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain.. The Journal of ...
https://memory.ucsf.edu/people/lea-grinberg-md-phd
*  Adelaide Research & Scholarship: Fine-scale survey of X chromosome copy number variants and indels underlying intellectual...
DNA Copy Number Variations; Intellectual Disability. Rights: Copyright © 2010 The American Society of Human Genetics. All ... We identified pathogenic copy number variants in 10% of families, with mutations ranging from 2 kb to 11 Mb in size. The ... Copy number variants and indels in 251 families with evidence of X-linked intellectual disability (XLID) were investigated by ... Fine-scale survey of X chromosome copy number variants and indels underlying intellectual disability. ...
https://digital.library.adelaide.edu.au/dspace/handle/2440/60709
*  The change of mtDNA copy number after PAHs exposure. mt | Open-i
mtDNA copy number was increased after exposure of PAHs with different pattern in THP-1 cell line (a) and in ... The change of mtDNA copy number after PAHs exposure. ... DNA Copy Number Variations/drug effects*. *DNA, Mitochondrial/ ... fig3: The change of mtDNA copy number after PAHs exposure. mtDNA copy number was increased after exposure of PAHs with ... fig3: The change of mtDNA copy number after PAHs exposure. mtDNA copy number was increased after exposure of PAHs with ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4121044_BMRI2014-605135.003&req=4
*  Variations in gut microbiota and fecal metabolic phenotype associated with Fenbendazole and Ivermectin Tablets by 16S rRNA gene...
Dna Copy Number Variations. Stretches of genomic DNA that exist in different multiples between individuals. Many copy number ... DNA sequencing DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. During DNA ... A form of interference microscopy in which variations of the refracting index in the object are converted into variations of ... Variations in gut microbiota and fecal metabolic phenotype associated with Fenbendazole and Ivermectin Tablets by 16S rRNA gene ...
https://www.bioportfolio.com/resources/pmarticle/2003507/Variations-in-gut-microbiota-and-fecal-metabolic-phenotype-associated-with-Fenbendazole-and.html
*  Focal high copy number gains and homozygous deletions i | Open-i
Focal high copy number gains and homozygous deletions in glioblastomas.Copy number analysis using DK and Illumina BeadChips ... DNA Copy Number Variations. *Gene Expression. *Gene Expression Profiling. *Gene Expression Regulation, Neoplastic ... Figure 1: Focal high copy number gains and homozygous deletions in glioblastomas.Copy number analysis using DK and Illumina ... A) Glioblastoma copy number karyotype generated utilizing Nexus Copy Number Professional Software (BioDiscovery Inc.). The most ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2992381_oncotarget-01-265-g001&req=4
*  Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma.
DNA Copy Number Variations / genetics. Humans. Kaplan-Meier Estimate. Melanoma / genetics*. Microarray Analysis. Mutation / ... 1). An evaluation of DNA copy number in 30 of the uveal melanomas, including seven with SF3B1 mutations, revealed no loss of ... Thus, we re-sequenced these exons in a total of 102 primary uveal melanomas and matching blood DNA samples and identified SF3B1 ... L.A.W. managed the tissue bank and clinical database, and prepared DNA and RNA samples. A.M.B. participated in the conception ...
http://www.biomedsearch.com/nih/Recurrent-mutations-at-codon-625/23313955.html
*  Chromosomal alterations in exfoliated urothelial cells from bladder cancer cases and healthy men: a prospective screening study...
9-11%). About 1% of cells from tumor-free men showed polysomy of chromosomes 3, 7, or 17 or DNA loss at 9p21. Men aged ≥50 ... Tetrasomy of chromosomes 3, 7 and 17, and DNA loss at 9p21 were the most frequently observed forms of CNV. In bladder cancer ... Also, a small fraction of cells with CNVs were exfoliated into urine of tumor-free men, mainly exhibiting tetraploidy or DNA ... Here, we analyzed the accumulation of copy number variations (CNVs) using fluorescence in situ hybridization in cancer cases ...
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-854
*  Basic Medical Science Publications (UMKC)
A Bayesian Analysis for Identifying DNA Copy Number Variations Using a Compound Poisson Process  Chen, Jie; Yiğiter, Ayten; ... technique is often used for detecting DNA copy number variants (CNVs). Various ... ... Abstract Background With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
https://mospace.umsystem.edu/xmlui/handle/10355/14253
*  Academic Programs Faculty - Last Initial T - Wake Forest School of Medicine
Proto-Oncogenes; DNA Copy Number Variations; Genetic Markers; Prostatectomy; Genes, p16 Academic: 336-716-7975. Department: 336 ...
http://www.wakehealth.edu/School/FacultySR.htm?st=T&li=T&ft=R
*  Umbricht C[au] - PubMed - NCBI
DNA copy number variations characterize benign and malignant thyroid tumors.. Liu Y, Cope L, Sun W, Wang Y, Prasad N, ... DNA methylation-related vitamin D receptor insensitivity in breast cancer.. Marik R, Fackler M, Gabrielson E, Zeiger MA, ... Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC ... Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Umbricht+C%5Bau%5D&dispmax=50
*  Customer Publications | BioDiscovery
DNA copy number variation and gene expression analyses reveal the implication of specific oncogenes and genes in GBM.. ... Germline DNA copy number variations as potential prognostic markers for non-muscle invasive bladder cancer progression.. ... Copy number variations are a rare cause of non-CMT1A Charcot-Marie-Tooth disease.. Huang J, Wu X, Montenegro G, Price J, Wang G ... Detection of copy number alterations in cell-free tumor DNA from plasma.. Østrup O, Ahlborn LB, Lassen U, Mau-Sørensen M, ...
https://www.biodiscovery.com/resources/customer-publications