Dive into the research topics of High-throughput sequencing SELEX for the determination of DNA-binding protein specificities ... High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro. ...
DNA-Binding Proteins - HMGB Proteins PubMed MeSh Term *Overview. Overview. subject area of * Interactions of HMGB Proteins with ... The DNA binding high mobility group box protein family functionally binds RNA Journal Article ... DNA-Binding Proteins - HMGB1 Protein PubMed MeSh Term * DNA-Binding Proteins - HMGB2 Protein PubMed MeSh Term ... DNA-Binding Proteins PubMed MeSh Term narrower concept * ... DNA-Binding Proteins - HMGB3 Protein PubMed MeSh Term ©2023 ...
title = "DNA binding by single HMG box model proteins",. abstract = "The HMG1/2 family is a large group of proteins that share ... DNA binding by single HMG box model proteins. / Xin, Hong; Taudte, Susann; Kallenbach, Neville R. et al. In: Nucleic acids ... DNA binding by single HMG box model proteins. Hong Xin, Susann Taudte, Neville R. Kallenbach, M. Paullin Limbach, Richard S. ... DNA binding by single HMG box model proteins. Nucleic acids research. 2000 Oct 15;28(20):4044-4050. doi: 10.1093/nar/28.20.4044 ...
The p120(ctn)-binding protein Kaiso is a DNA-specific, methylation-sensitive transcription factor Conferences ...
... including a much larger DNA-binding site with an 18 bp (~60 Å) spacer between the two palindromic DNA-binding sequences and a ... including a much larger DNA-binding site with an 18 bp (~60 Å) spacer between the two palindromic DNA-binding sequences and a ... including a much larger DNA-binding site with an 18 bp (~60 Å) spacer between the two palindromic DNA-binding sequences and a ... Structural analysis of DNA binding by C.Csp231I, a member of a novel class of R-M controller proteins regulating gene ...
DNA-Binding Proteins - Proto-Oncogene Proteins c-maf PubMed MeSh Term *Overview ...
a sugar/carbohydrate, a lipid, another protein, or even a molecule of DNA or RNA). For this task you will investigate the ... and the molecule that interacts with and is bound by the protein is referred to by biochemists as a ligand. Chemists usually ... of the protein are directly involved in forming the protein-ligand complex, i.e. to explain how the interaction occurs. You are ... The task Proteins are the most prevalent macromolecules in biological systems. They are extraordinarily diverse in terms of ...
... when a protein bound to the DNA presents a lattice for the next-layer binding of other proteins), and protein-assisted DNA ... DNA-protein binding in chromatin. Although binding events are very complex, gene regulation is still centered on the DNA or RNA ... competitions between different protein types or different binding modes; interactions between proteins bound to the DNA; ... Basic features of DNA-protein-drug binding encountered in gene regulation include site specificity determined by the DNA ...
An emerging theme in our current understanding of human oncogenesis is that cancers arise as mutations and epigenetic alterations accumulate in individual cells. The ultimate consequence of such changes is to alter the expression profile of the genome. ...
For this, we would make use of datasets about containing DNA-binding proteins and the DNA sequences they bind to. I was looking ... Right now, we would like to examine protein-DNA binding properties computationaly. ... You are seeking a database of transcription factor binding specificities. Some model organism databases (which are manually ... I am a computer scientist and we are working on protein function prediction algorithms. ...
Decades ago, it was shown that proteins binding to DNA can quantitatively alter the formation of DNA damage by UV light. This ... Base-resolution UV footprinting by sequencing reveals distinctive damage signatures for DNA-binding proteins. ... Our work provides proof of concept for the study of protein-DNA interactions at individual loci using light and sequencing, and ... established the principle of UV footprinting for non-intrusive study of protein-DNA contacts in living cells, albeit at limited ...
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody, Cat#CAU25007. Rating Required Select Rating. 1 star (worst). 2 stars ... Title: Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic ...
Dive into the research topics of NMR structure of the DNA-binding domain of the cell cycle protein Mbp1 from Saccharomyces ... NMR structure of the DNA-binding domain of the cell cycle protein Mbp1 from Saccharomyces cerevisiae. ...
genome copy number variation and genome-wide profiling of DNA-binding proteins June 14, 2021. Monoclonal, Mouse monoclonal, ... genome copy number variation and genome-wide profiling of DNA-binding proteins ... genome copy number variation and genome-wide profiling of DNA-binding proteins ... When a protein is tagged by fusion to a fluorescent protein, interactions between fluorescent proteins can undesirably disturb ...
N2 - The architecture of single-stranded DNA-binding proteins, which play key roles in DNA metabolism, is based on different ... AB - The architecture of single-stranded DNA-binding proteins, which play key roles in DNA metabolism, is based on different ... The architecture of single-stranded DNA-binding proteins, which play key roles in DNA metabolism, is based on different ... abstract = "The architecture of single-stranded DNA-binding proteins, which play key roles in DNA metabolism, is based on ...
... Nechipurenko Yu.D. ... active compounds to DNA in solution and to shed light on the nature of the mechanisms underlying the protein binding with ... The report demonstrates the possibility of application of statistical thermodynamics for analysis of the binding of proteins, ... which presents a wide variety of mathematical models describing the binding of ligands to DNA and are not included in the guide ...
... we identified novel Smad targets including protein tyrosine phosphatase receptor type kappa (PT … ... DNA-Binding Proteins / metabolism* * Epidermal Growth Factor / metabolism * Female * Focal Adhesion Kinase 1 ... receptor type protein tyrosine phosphatase kappa, the protein product encoded by the PTPRK gene) protein in tumor and nontumor ... Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required ...
Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins.. Zheng, Luqian; Liu, Jingjing; ... which reveals how BEND3 identifies cognate DNA targets and shows differences with one of its non-DNA-binding BEN domains (BD1 ... The BEN domain is a recently recognized DNA binding module that is present in diverse metazoans and certain viruses. Several ... activities of BEN factors and provide structural insights into sequence-specific DNA binding by mammalian BEN proteins. ...
This hitherto unseen mode of DNA binding by TrmBL2 seems to arise from nonoptimal protein-DNA contacts made by its four HTH ... domains binding to successive major grooves of the DNA. However, in TrmBL2, the two dimers are arranged at a mutual ... domains resulting in a low-affinity, nonspecific binding to DNA. ... of approximately 2 bp so that they associate with the DNA along ... While the deoxyribose phosphate groups of the double-stranded DNA (dsDNA) used for co-crystallization are clearly seen in the ...
The CHD7 gene provides instructions for making a protein called chromodomain helicase DNA binding protein 7. Learn about this ... The CHD7 gene provides instructions for making a protein called chromodomain helicase DNA binding protein 7. This protein is ... Chromatin is the complex of DNA and protein that packages DNA into chromosomes. The CHD7 protein regulates the activity ( ... The CHD7 protein belongs to a family of proteins that are thought to play a role in the organization of chromatin. ...
... Musiani F;Bertosa B;MAGISTRATO, ... The presence of the bound Ni2+ ions does, however, affect significantly the degree of the correlations on the two DNA-binding ... The presence of the bound Ni2+ ions does, however, affect significantly the degree of the correlations on the two DNA-binding ... Overall, the findings suggest that the binding of HpNikR to DNA occurs through a sophisticated multistep process that might ...
DNA-binding proteins able to switch between an on (binding) and an off (nonbinding) state. This system provides a model for ... any DNA-binding protein that can be posttranslationally modified to change its affinity for DNA (e.g., through phosphorylation ... when these bind to DNA nonspecifically, they form clusters that grow indefinitely in size. To explain these findings, we ... Protein switching also reshapes intrachromatin contacts to give networks resembling those seen in topologically associating ...
Prionlike propagation of misfolding of proteins-in particular, SOD1 and the 43 kDa transactive response DNA binding protein ( ... In 2006, ubiquitinated inclusions containing pathologic forms of TAR DNA-binding protein-43 (TDP-43) were identified in the ... They regulate the translation of mRNA to protein by binding to complementary RNA segments on mRNA, thereby interfering with ... An alternative trigger for disease onset might be appearance of a misfolded intracellular protein that induces other proteins ...
Dive into the research topics of Purification and characterization of a DNA-binding protein activated by ionizing radiation. ... Purification and characterization of a DNA-binding protein activated by ionizing radiation. ...
The sperm DNA integrity was assessed by acridine orange stain method. There was no significant difference among control (90.15 ... The sperm DNA integrity was assessed by acridine orange stain method. There was no significant difference among control (90.15 ... This study indicated that HBP supplementation in capacitation medium did not alter the sperm morphology and DNA integrity. ... This study indicated that HBP supplementation in capacitation medium did not alter the sperm morphology and DNA integrity. ...
In eukaryotic cells, the genome is packaged and rolled up by histone proteins to create a series of DNA/histone core structures ... that highlight how chromatin structure and chromatin binding proteins alter transcription in response to environmental changes ... Histones can be modified chemically by a large number of proteins that are thereby responsible for dynamic changes in gene ... DNA-binding proteins Is the Subject Area "DNA-binding proteins" applicable to this article? Yes. No. ...