Genetics and Epigenetics of Bipolar Disorder - Nova Science Publishers
Keywords: GWAS, SNPs, Association study, DNA methylation, ion channel, signaling pathway, cell adhesion ... differential DNA methylation has been observed in both coding genes (HTR1A, MB-COMT CTNNA2 and MHR1) and non-protein coding ...
Methylenetetrahydrofolate Reductase (MTHFR) in Health and Disease - Nova Science Publishers
The Link Between MTHFR C677T Polymorphism, Folate Metabolism and Global DNA Methylation: A Literature Review. (Antonella Agodi ... health implications and the role folate deficiency and MTHFR polymorphisms may play in the complex mechanism of global DNA ...
A Closer Look at the Comet Assay - Nova Science Publishers
New applications of the comet assay are described for the detection of aberrant DNA methylation, which is a promising marker in ... Chapter 5. Evaluation of Global DNA Methylation Status of Single Cells by the Comet Assay: A Promising Approach in Cancer ... arguing that in neutral conditions at low levels of DNA damages, the comet tail is formed by extended DNA loops. ... Next, to shed light on the mechanisms of the DNA track formation, the authors apply an original approach based on the kinetic ...