Nutrients | Free Full-Text | Dietary Interventions with Polyphenols in Osteoarthritis: A Systematic Review Directed from the...
... a disintegrin and metalloprotease with thrombospondin motifs (ADAMTS). In this unfavorable environment, ACs proliferate and ...
Toxins | August 2018 - Browse Articles
Disintegrins are a family of small cysteine-rich peptides, found in a wide variety of snake venoms of different phylogenetic ... Disintegrins are a family of small cysteine-rich peptides, found in a wide variety of snake venoms of different phylogenetic ... Most disintegrins interact with integrins through the RGD (Arg-Gly-Asp) sequence loop, resulting in an active site that ... This review provides highlights of the biological relevance and contribution of recombinant disintegrins to the understanding ...
Viruses | Free Full-Text | Cellular Prion Protein: From Physiology to Pathology
... provided the first evidence implicating the responsible metalloproteases as the disintegrins ADAM10 (A disintegrin and ... Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice. Dev.Dyn. 2005, 232, 221-231. [Google ... The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular ... Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular ...
Vaccines | Free Full-Text | The Increase of the Magnitude of Spontaneous Viral Blips in Some Participants of Phase II Clinical...
Nef increases the production of exosomes containing activated ADAM17 (a disintegrin and metalloprotease domain 17), an enzyme ...
Pharmaceuticals | March 2021 - Browse Articles
Under in vitro OA mimic conditions, the expression of the matrix metalloproteinases (MMPs) MMP3/13 and a disintegrin and ...
Toxins | Free Full-Text | Inhibition of Hemorragic Snake Venom Components: Old and New Approaches
CRISP and disintegrins) that activate or inhibit coagulant factors or platelets, or disrupt the endothelium [15]. To date, ... PLA2 and metalloproteases with disintegrin domains are among the major venomous enzymatic components of hemotoxic Viperidae ...
Pharmaceutics | Free Full-Text | Retinoic Acid Receptor Is a Novel Therapeutic Target for Postoperative Cognitive Dysfunction
... a disintegrin and metalloprotease 10 (ADAM10), calbindin 1 (Calb1), and erb-b2 receptor tyrosine kinase 4 (Erbb4) were ...