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*  Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer - Full Text View -...
Progression of measurable disease as defined by RECIST. *Progression of bone disease as defined by the appearance of one or ... Documented progression of disease after one taxane based prior chemotherapy regimen for HRPC. Progression is defined as at ... Time to Progression [ Time Frame: Study enrollment until progression per RECIST or PSA (for life) ]. Progression per Response ... Best Overall PSA Response [ Time Frame: Start of treatment until disease progression/recurrence (for life) ]. Best overall ...
https://clinicaltrials.gov/ct2/show/NCT00216099
*  Intermittent Taxotere® Effective in Hormone-refractory Prostate Cancer
... men who received CA Taxotere administered once every three weeks or IA Taxotere administered at measurable cancer progression ... Disease Specific Sites *Brain Cancer Sites. *Breast Cancer Sites. *Chemotherapy Sites. *Childhood Cancer Sites ...
http://cancer.unm.edu/2009/03/08/intermittent-taxotere-effective-in-hormone-refractory-prostate-cancer/
*  'Wait and See' Surveillance For Low Risk Prostate Cancer Has...
Management of low risk prostate cancer with AS appears feasible and safe, but most men in the U.S. with low risk disease still ... During AS, prostate cancer is carefully monitored for signs of progression. A PSA blood test and digital rectal exam (DRE) are ... Prostate Cancer News Today is strictly a news and information website about the disease. It does not provide medical advice, ... The new study followed men in the Center for Prostate Disease Research Multicenter National Database who underwent prostate ...
https://prostatecancernewstoday.com/patients-with-low-risk-prostate-cancer-on-active-surveillance-experience-good-quality-of-life/
*  Papers with the keyword late-stage neuroendocrine prostate cancer | Read by QxMD
... and 15 metastatic tumors from 72 patients at different stages of disease progression to t-NEPC, some with multiple specimens... ... BACKGROUND: Animal models that closely mimic clinical disease can be exploited to hasten the pace of translational research. To ... Circulating tumor cells capture disease evolution in advanced prostate cancer.. Justin Lack, Marc Gillard, Maggie Cam, Gladell ... Neuroendocrine (NE)-like cells are hypothesized to contribute to the progression of prostate cancer by producing factors that ...
https://www.readbyqxmd.com/keyword/115753
*  Vascular Targeted Photodynamic Therapy with Padeliporfin for Low Risk Prostate Cancer Treatment: Midterm Oncologic Outcomes.,...
Disease Focus. Read carefully compiled disease summaries which detail how our system of categorisation is put together. ... Progression-free survival is reported with Kaplan-Meier curves.. Results: A total of 82 men were treated with vascular targeted ... Median followup was 68 months (range 6 to 89). Median progression-free survival was 86 months (95% CI 82-90). Median prostate ... The primary end point was progression-free survival. Secondary end points were absent clinically significant cancer in the ...
https://www.epgonline.org/uk/journals/vascular-targeted-photodynamic-therapy-with-padeliporfin-for-low-risk-prostate-cancer-treatment--mid.html
*  Alzheimer's disease progression predicted by gene mutation
... type shows that a mutation in the gene coding for brain-derived neurotrophic factor may predict Alzheimer's disease progression ... Because current treatment is most successful if given earlier in the disease's progression, this could be a vital part of the ... Researchers find that a certain gene mutation might predict Alzheimer's progression. Alzheimer's disease is the most common ... Blood screening tests could predict Alzheimer's disease Blood screening tests to detect levels of an Alzheimer's disease marker ...
https://www.medicalnewstoday.com/articles/317269.php?bl
*  MAPK Usage in Periodontal Disease Progression
... signaling axis is needed for periodontal disease progression: an orally administered p38α inhibitor reduced the progression of ... MAPK Usage in Periodontal Disease Progression. Qiyan Li,1 Michael S. Valerio,2 and Keith L. Kirkwood2 ... MAPK phosphatase-1 (MKP-1), a negative regulator of MAPK activation, was also critical for periodontal disease progression. In ... these studies highlight the importance of p38 MAPK signaling in immune cytokine production and periodontal disease progression. ...
https://www.hindawi.com/journals/jst/2012/308943/abs/
*  Parkinson's: Could this existing drug halt disease progression?
... that is commonly used to treat tapeworm infections is found to contain a molecule that can protect against Parkinson's disease. ... Parkinson's disease may begin in the gut Parkinson's disease may start in the gut, suggest researchers. The neurogenerative ... The findings bring us closer to slowing or even stopping neurodegeneration in this disease.. An existing drug may soon be used ... "We will now take our findings to the next level by evaluating the ability of niclosamide to treat Parkinson's disease in ...
https://www.medicalnewstoday.com/articles/320356.php
*  Guanabenz Accelerates ALS Disease Progression in Preclinical Laboratory Experiments
In these studies from the Institute, treatment of SOD1 mice with guanabenz actually accelerated disease progression. These ... in ALS disease progression. While most ALS has not yet been linked to specific genetic mutations, at least 10% of cases have ... Led by ALS patients and their families, the charity understands the urgent need to slow and stop this horrible disease. Based ... research reports have suggested a neuroprotective effect by guanabenz in SOD1 mice resulting in slower disease progression and ...
http://www.prweb.com/releases/2015/08/prweb12911582.htm
*  Epigenomics of Alzheimer's disease progression - ScienceBlog.com
Our susceptibility to disease depends both on the genes that we inherit ... Study of epigenomic modifications reveals immune basis of Alzheimer's disease. ... "Our data suggest that microglia are heavily activated during Alzheimer's disease progression, although it is unknown exactly ... "We found two opposing signatures associated with disease progression that are consistent with the pathophysiology of ...
https://scienceblog.com/77053/epigenomics-of-alzheimers-disease-progression/
*  NSCLC Combo Slows Disease Progression | Medpage Today
Progression of non-squamous non-small cell lung cancer slowed by almost half when pemetrexed (Alimta) and erlotinib (Tarceva) ... The progression hazard ratio was 0.57 for the comparison with erlotinib alone (P=0.002) and 0.58 for the comparison with ... Progression of non-small cell lung cancer slowed by almost half when pemetrexed (Alimta) and erlotinib (Tarceva) were used in ... VIENNA -- Progression of non-squamous non-small cell lung cancer (NSCLC) among never- and former light-smoker patients slowed ...
https://www.medpagetoday.com/meetingcoverage/esmo/35190
*  Experimental Drug Stops Parkinson's Disease Progression in Mice
Researchers stop Parkinson's disease progression in mice by blocking astrocyte conversion. Credit: iStock ... Researchers say they have developed an experimental drug that slows the progression of Parkinson's disease itself ... that slows the progression of Parkinson's disease itself - as well as its symptoms - in mice. In experiments performed with ... it could be one of the first treatments to directly target the progression of Parkinson's disease, not just the muscle rigidity ...
https://www.hopkinsmedicine.org/news/newsroom/news-releases/experimental-drug-stops-parkinsons-disease-progression-in-mice
*  Receptor Mutations Help Slow Disease Progression | Science
Population geneticist Stephen O'Brien of the National Cancer Institute and a large group of collaborators have amassed strong confirmatory evidence that people who have two mutant copies of the gene for a chemokine receptor known as CCR5 (also known as CKR5) are highly resistant to HIV infection. The findings, published on page1856 , also indicate that people who do get infected with HIV, but have one mutant copy of the CCR5 gene, progress to AIDS more slowly than do people without the mutation.. ...
http://science.sciencemag.org/content/273/5283/1797
*  Typical Acute Retroviral Syndrome Disease Progression - The Body
... typical acute retroviral syndrome disease progression, with a wealth of fact sheets, expert advice, community perspective, the ... thrush= disease progression?. Hello Dr. Feinberg,I've been trying to get answer to this for months, but no luck. A bit ... Acute HIV infection or Disease progression?. Dr. Holodniy,My last negative HIV test was May of 1999. In November and December I ... The information provided through The Body should not be used for diagnosing or treating a health problem or a disease. It is ...
http://www.thebody.com/h/typical-acute-retroviral-syndrome-disease-progression.html
*  Lou Gehrig's disease progression: | Sciforums
Researchers show how Lou Gehrig's disease progression could be delayed February 9, 2017 [IMG] Pellecchia and colleagues ... Researchers show how Lou Gehrig's disease progression could be delayed. February 9, 2017. Please Register or Log in to view the ... Lou Gehrig's disease progression:. Discussion in 'Biology & Genetics' started by paddoboy, Feb 9, 2017. ... sometimes known as Lou Gehrig's disease, the neurodegenerative disease that affects motor neurons - nerve cells in the brain ...
http://sciforums.com/threads/lou-gehrigs-disease-progression.158870/
*  Occasional Heroin Use Impacts HIV Disease Progression
Occasional heroin use by HIV-positive patients may be harmful to the immune system and worsen HIV disease, compared to ... E. Jennifer Edelman and her co-authors were interested in whether heroin use impacted HIV disease progression. 77 HIV-infected ... "AIDS is an epidemic disease, a potentially preventable, deadly infection for which there is no cure, no vaccine, and it is not ... The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always ...
http://www.medindia.net/news/occasional-heroin-use-impacts-hiv-disease-progression-144938-1.htm
*  Atherosclerosis Disease Progression Cell Markers
To get started with seeing how the Atherosclerosis Disease Progression Cell Markers tool can benefit you, follow these easy ... Detail from the Atherosclerosis Disease Progression Cell Markers tool. Phenotyping links connect to antibodies validated for ... Home » Resources » Blog » Atherosclerosis Disease Progression Cell Markers. Atherosclerosis Disease Progression Cell Markers. ...
https://www.rndsystems.com/blog/atherosclerosis-disease-progression-cell-markers
*  Vitamin E may slow Alzheimer's disease progression | HeraldNet.com
Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer's disease - the first time any treatment has ... Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer's disease - the first time any treatment has ... Antioxidants help protect cells from damage that can contribute to other diseases, says the federal Office on Dietary ... "The best we can do at this point is slow down the rate of progression." ...
http://www.heraldnet.com/news/vitamin-e-may-slow-alzheimers-disease-progression/
*  Small Markers May Pinpoint Disease Progression
... and looked at the clinical symptoms to find markers that might show the odds for disease progression. The results showed that ... did not help in predicting disease progression. Positive rheumatoid factor (an antibody detected in a blood test), some genetic ... Also, 48% of the patients did not develop progressive disease. (These findings were published in Arthritis & Rheumatism, ... disease state management, patient counseling, product news, pharmacy law and health-system pharmacy. Pharmacy Times Continuing ...
http://www.pharmacytimes.com/publications/issue/2004/2004-03/2004-03-7718
*  disease progression Archives ~ HCV Advocate
HCV Disease Progression. Click on a title below to view or download the PDF about that subject.. Overview of HCV Disease ... Filed Under: Espanol, Publications, Spanish Tagged With: cirrhosis, disease progression, fact sheets, fibrosis, steatosis ... Studies have found that the combination of hepatitis C and steatosis increases the risk of HCV disease progression and may ... Filed Under: Factsheets, Publications Tagged With: cancer, cirrhosis, disease progression, fibrosis, steatosis ...
http://hcvadvocate.org/tag/disease-progression/
*  Vitamin E may slow Alzheimer s disease progression
Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer s disease the first time any treatment has ... Vitamin E may slow Alzheimer's disease progression. Associated Press Alexis McKenzie, right, executive director of The ... Researchers say vitamin E might slow the progression of mild-to-moderate Alzheimer s disease the first time any treatment has ... researchers report that vitamin E might slow the progression of mild to moderate Alzheimer s disease. The study of more than ...
http://www.dailylocal.com/lifestyle/20140106/vitamin-e-may-slow-alzheimers-disease-progression
*  Visualizing Sudden Oak Death, Part 4: Disease progression in tanoaks - YouTube
Parts 1 through 3 describe different disease outcomes that occur in coast live oak, Quercus agrifolia. Part 4 describes disease ... Sudden oak death is a lethal disease that affects several species of oaks and tanoak. ...
https://www.youtube.com/watch?v=0FukMPDWrCU
*  Medical Xpress - disease progression
Medical Xpress is a web-based medical and health news service that features the most comprehensive coverage in the fields of neuroscience, cardiology, cancer, HIV/AIDS, psychology, psychiatry, dentistry, genetics, diseases and conditions, medications and more.
https://medicalxpress.com/tags/disease+progression/sort/date/12h/
*  Frontiers | Parkinson's Disease: Cell Vulnerability and Disease Progression
The hallmark feature of this disease is the degeneration of dopamine neurons in the... ... Parkinson's disease is a neurodegenerative disorder that affects 1.5% of the global population over 65 years of age. ...
https://www.frontiersin.org/books/Parkinson_s_Disease_Cell_Vulnerability_and_Disease_Progression/754
*  HCV /HIV Nonresponders Experience Improved Disease Progression
Does Interferon Slow HCV Disease & Improve Survival. Interferon therapies are associated with significant side effect profiles ... This finding was secondary to the reduction in risk of death from liver disease in the treated group as the risk of dying from ... 86 deaths were noted amongst the group with 58 (67%) attributable to liver disease. 39 deaths were due to liver cancer, 12 ... degree of liver disease on biopsy or resting energy expenditure. This study highlights two important points. The first is that ...
http://www.natap.org/2002/DDWLiver/day10.htm