Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted ... Liu MJ, Wang Z, Ju Y, Wong RN, Wu QY (2005). "Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells ... Diosgenin is a precursor for several hormones, starting with the Marker degradation process. This includes progesterone which ... "2950 Diosgenin". Retrieved 2007-05-29. [permanent dead link] Marker RE, Krueger J (1940). "Sterols. CXII. Sapogenins. XLI. The ...
Remarkably, it was evidenced that dioscin has better intestinal permeability than diosgenin and is converted to diosgenin in ... Further studies also demonstrated that the inhibition of autophagy potentiated the diosgenin-induced apoptosis [1]. Diosgenin ... showing a linearity range for diosgenin from 1.0 to 3.0 μg−1 per spot. This study allowed the quantification of diosgenin not ... diosgenin revealed to be an interesting molecule in some viral diseases. In fact, due to its antioxidant activity, diosgenin ...
In vitro, diosgenin had no effect on the activity of rat pancreatic esterase. Diosgenin decreased the elevated cholesterol in ... Diosgenin had no effect on cholesterol synthesis when added to normal rat liver homogenates. It was concluded that diosgenin ... diosgenin had no effect on bile acid binding. Diosgenin treatment increased hepatic and intestinal cholesterol synthesis as ... Diosgenin fed with the diet for 1 week inhibited cholesterol absorption as determined by the serum isotope ratio technique, as ...
Diosgenin (DSG), a well-known steroid sapogenin derived from Dioscorea nipponica Makino and Dioscorea zingiberensisWright, has ... The effects of diosgenin in the regulation of renal proximal tubular fibrosis. Exp Cell Res. 2014;323:255-62.CrossRefPubMed ... Gao M, Chen L, Yu H, Sun Q, Kou J, Yu B. Diosgenin down-regulates NF-κB p65/p50 and p38MAPK pathways and attenuates acute lung ... bioavailability diosgenin media milling nanocrystals pharmacokinetics Electronic supplementary material. The online version of ...
Our in vivo data indicate that diosgenin is a memory-enhancing drug and that enhancement by diosgenin is mediated by 1,25D3- ... In diosgenin-treated mice, axonal density and c-Fos expression was increased in the medial prefrontal and perirhinal cortices, ... Diosgenin treatment in normal mice enhanced object recognition memory and spike firing and cross-correlation in the medial ... The diosgenin-induced memory enhancement and axonal growth were completely inhibited by co-treatment with a neutralizing ...
Diosgenin L, Diosgenin M, and Diosgenin H: orally given diosgenin 20, 40, and 80 mg/kg of low, medium and high dose, ... diosgenin treatment groups. For the diosgenin groups, diosgenin was administered at rates of 20, 40, or 80 mg/kg for 3 days ... we hypothesized that diosgenin is a bioactive metabolite related to the antimyocardial ischemia (MI) activity of DN. Diosgenin ... was attributed to diosgenin. This finding confirmed our hypothesis that intestinal bacteria produce diosgenin from DN extract [ ...
Diosgenin definition: a substance obtained from the yam (genus Dioscurea ), used to produce cortisone ,... , Meaning, ... diosgenin is in the lower 50% of commonly used words in the Collins dictionary ...
Arginyl-diosgenin Adult neurogenesis LPS Microglia Neuroinflammation NF-κB JNK signaling Bangrong Cai and Kyung-Joo Seong ... Liu W, Zhu M, Yu Z, Yin D, Lu F, Pu Y, Zhao C, He C et al (2017) Therapeutic effects of diosgenin in experimental autoimmune ... Gao M, Chen L, Yu H, Sun Q, Kou J, Yu B (2013) Diosgenin down-regulates NF-kappaB p65/p50 and p38MAPK pathways and attenuates ... Zhang X, Xue X, Zhao J, Qian C, Guo Z, Ito Y, Sun W (2016) Diosgenin attenuates the brain injury induced by transient focal ...
... diosgenin content 2.85-fold, and diosgenin yield 3.83-fold in comparison to those of control. EPS and SPS showed moderate and ... The dynamics of cell growth and diosgenin accumulation when WPS was added to the medium at 20 mg/L on the 25th day of culture ... The effects of the time of addition and polysaccharide concentration on the growth and diosgenin accumulation in cell ... were investigated, and results showed that dry weight of cells reached a maximum value on day 30 but the maximum diosgenin ...
We have shown that diosgenin is a potent candidate for decreasing the ability of invasion and survival in cobalt chloride ... The anti-invasion role of diosgenin may be related to E-cadherin, integrinα5 and integrinβ6. These results suggest that ... In addition, when combined with HIF-1α specific short hairpin RNA (shRNA), diosgenin can inhibit BGC-823 cells more effectively ... Here, we identified a hypoxia-mimic (cobalt chloride) sensitive gastric cell line BGC-823 to explore whether diosgenin, an ...
Diosgenin, a commercially important bioactive sapogenin, extracted from tubers belonging to Dioscorea species, is used as a ... Diosgenin was quantified from the fresh tuber, dried tuber powder and its callus. Further increase in diosgenin content, by ... Table 2: Densitometer scanning results of std Diosgenin and samples.. The amount of Diosgenin in fresh and dried tuber as well ... Diosgenin (ng). STD added (ng). Total Conc.. Actual Conc.. % Recovery. Fresh tuber pwd. 36813.57. 100. 36913.57. 36909.75. ...
DIOSGENIN) turns out to protect the brain! Natural progesterone is a protective agent against Alzheimer s and Stroke! ...
Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 ...
Diosgenin attenuates HSC activation by inhibiting transforming growth factor-β. Aim: In present study an attempt was made to ... Diosgenin are the steroidal saponin and found in Trigonella foenum graecum Linn (Fenugreek) and some other species of Dioscorea ... PROTECTIVE EFFECT OF DIOSGENIN AGAINST CARBON TETRACHLORIDE AND CISPLATIN INDUCED HEPATOTOXICITY IN RATS ... Conclusion: The result obtained in the present investigation, Diosgenin treatment exerted significant hepatoprotective effect ...
Simultaneous Determination of Diosgenin and Guggulsterone-Z in gokshuradi guggulu tablet by High-Performance Thin-Layer ... respectively and for diosgenin 9.23 and 24.15 ng/ spot, respectively. The proposed method can be successfully used to determine ... calibration curve was found to be linear between 200 to 800 ng/spot for guggulosterone Z and 50 to 350 ng/spot for diosgenin. ... validate a high performance thin layer chromatography method for simultaneous determination of Guggulosterone-Z and Diosgenin ...
Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis . - Mechanism of ... Diosgenin glucoside, a saponin compound extracted from Tritulus terrestris L., provides neuroprotection by regulating ... Diosgenin glucoside Cat. No.: HY-N0730 Data Sheet Handling Instructions Diosgenin glucoside, a saponin compound extracted from ... Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2]. ...
Objective: To assess the efficacy and safety of an association of diallyl thiosulfinate with nuciferine and diosgenin in the ... The role of diallyl thiosulfinate associated with nuciferine and diosgenin in the treatment of premature ejaculation: A pilot ... Nuciferine and Diosgenin is able to improve the control of ejaculation in patients suffering from PE, primary or secondary to ... The role of diallyl thiosulfinate associated with nuciferine and diosgenin in the treatment of premature ejaculation: A pilot ...
Diosgenin): Side Effects & Safety - Pharmaceutical Ingredients Manufacturer & Supplier ... Wild Yam(Diosgenin): Side Effects & Safety Outrageous yam is POSSIBLY RISK-FREE when taken by mouth or applied to typically the ...
Category Archives: Diosgenin. Diosgenin and Lovastatin Prevent Bone Loss in Ovariectomized Rat Abstract. Osteoprotective effect ... DHEA or Diosgenin Prevents Bone Loss in Ovariectomized Rats Abstract. The use of estrogen, DHEA, and diosgenin in a sustained ... Diosgenin Stimulates Bone Formation In Mouse Osteoblasts Abstract. Diosgenin stimulates osteogenic activity by increasing bone ... Diosgenin Promotes Angiogenesis in Preosteoblast-Like Mouse Cells Abstract. Diosgenin induces hypoxia-inducible factor-1 ...
Diosgenin is a steroid sapogenin and the forerunner for the semisynthesis of progesterone which in about-face was acclimated in ... Diosgenin Biological Activity January 20, 2015 Diosgenin is a steroid sapogenin and the forerunner for the semisynthesis of ... Diosgenin aswell causes an inhibition of the advance of fibroblast-like synoviocytes from animal rheumatoid arthritis, with ... Celecoxib, a careful COX-2 inhibitor, affronted a ample abatement in diosgenin-induced apoptosis even in the attendance of ...
Cov piam thaj dawb (aglycone), diosgenin yog siv rau kev lag luam synthesis ntawm cortisone, pregnenolone, progesterone, thiab ... Diosgenin, phytosteroid sapogenin, yog qhov khoom ntawm hydrolysis los ntawm acids, muaj zog hauv paus, los yog enzymes ntawm ... Diosgenin, phytosteroid sapogenin, yog qhov khoom ntawm hydrolysis los ntawm acids, muaj zog hauv paus, los yog enzymes ntawm ... saponins, muab los ntawm tubers ntawm Dioscorea qos yam, xws li cov Kokoro. Cov piam thaj dawb (aglycone), diosgenin yog siv ...
... führenden Wild Yam Extrakt Pulver Diosgenin Hersteller & Lieferanten, finden Wild Yam Extrakt Pulver Diosgenin Factory & ... China Wild Yam Extrakt Pulver Diosgenin mit hochwertigen, ... Fabrik Preis für Wild Yam Extrakt Diosgenin , Diosgenin für ... Beschreibung:Frisches Wild Yam Diosgenin im konkurrenzfähigen Preis,Fabrik Preis für Wild Yam Extrakt Diosgenin,Diosgenin für ... Englischer Name] Diosgenin [Produkt-Ressource] Dioscorea zingiberensis CHWright [Spezifikation] 95% [Testverfahren] HPLC [ ...
The maximum accumulation of diosgenin was noticed on the 14th day in control and cholesterol-treated cell suspension culture ... The highest concentration of diosgenin, 2.94% and 2.14% dry weight, was obtained in immobilised cell culture and cell ... Jyothishwaran, G and Seetharam, YN (2008) Biotransformation of cholesterol to diosgenin by freely suspended and immobilised ... Biotransformation;Cholesterol;Dioscorea bulbifera;Diosgenin;Growth index;Immobilisation.. Department/Centre:. Division of ...
Hydrophobically-modified Chitosan Microspheres for Release of Diosgenin Javier Perez Quinones1,*, Oliver Brüggemann1, Carlos ... The diosgenin content found using elemental analysis was ca. 6 to 42 wt-% and it showed dependence on the type of diosgenin ... Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells. ... Sustained diosgenin release in acidic aqueous solution (pH 6.0) reached from 34 to 81% after 48 h. ...
Steroidal sapogenin, diosgenin. It is a source of diosgenin, which is used to prepare synthetic hormones such as progesterone ... Studies on Diosgenin say that it has effect on diabetic neuropathy. Before becoming used industrially the tuber was used by ... Diosgenin extracted from Dioscorea composita was instrumental in the development of the combined oral contraceptive pill in the ... It is notable for its role in the production of diosgenin, which is a precursor for the synthesis of hormones such as ...