In vitro study showed that exendin-4 (the active ingredient of exenatide) attenuated HUVECs injury induced by high glucose, ... expression induced by high glucose in HUVECs. In conclusion, this study demonstrates that exenatide treatment can alleviate the ... R. R. S. Costa, N. R. Villela, M. D. G. C. Souza et al., "High fat diet induces central obesity, insulin resistance and ... M. Alemany, "Utilization of dietary glucose in the metabolic syndrome," Nutrition and Metabolism, vol. 8, no. 1, pp. 74-83, ...

A calorie-dense diet is a well-established risk factor for obesity and metabolic syndrome (MetS), whereas the role of the ... in the development of diet-induced obesity (DIO) is not completely understood. To test the hypothesis that Swiss Webster (Tac: ... PubMed Central ID. PMC7232377. Grant List. 1R01DK103761-01A1 / NH / NIH HHS / United States. 5R01AT009168 / NH / NIH HHS / ... Therefore, GF male Tac:SW mice developed several detrimental effects of obesity and MetS from a high-fat, calorie dense diet. ...

These results indicate that diet-induced obesity increases the risk of symptomatic features of osteoarthritis through changes ... A high-fat diet also induced symptomatic characteristics of osteoarthritis, including hyperalgesia and anxiety-like behaviors. ... Female C57BL/6J mice were fed either a 10% kcal fat or a 45% kcal fat diet from 9 to 54 weeks of age. Longitudinal changes in ... Controlling for the effects of diet and percentage body fat with a multivariate model revealed a significant association ...

... reported that maternal diet-induced obesity resulted in increased adult adiposity and evidence of cardiovascular and metabolic ... is associated with higher risks of central obesity, insulin resistance, the metabolic syndrome, type 2 diabetes, hypertension, ... which themselves are associated with later central obesity, insulin resistance, and metabolic syndrome. Very little current ... Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel ...

RELATIONSHIP BETWEEN MEDITERRANEAN DIET AND PHASE ANGLE IN A SAMPLE OF PATIENTS WITH OBESITY AND METABOLIC SYNDROME ... Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring. PLoS One ... Despres JP, Lemieux I: Abdominal obesity and metabolic syndrome. Nature 2006;444:881-887. ... The mechanisms through which maternal obesity may program obesity and related metabolic disorders during pregnancy and after ...

Alveolar hypoventilation is caused by several disorders that are collectively referred as hypoventilation syndromes. Alveolar ... Diet. Weight loss is an ideal treatment in obesity-hypoventilation syndrome. Weight loss improves the abnormal physiology and ... If the patients respiratory system cannot compensate for the metabolic acidosis it induces, the patient may suffer ... increases the central respiratory drive and it has been shown to be effective in obesity-hypoventilation syndrome and central ...

The metabolic syndrome (MS) is a cluster of risk factors, such as central obesity, hyperglycemia, dyslipidemia, and arterial ... diet induces proteases-mediated collagen degradation that could result in plaque instability. Further, the CC diet fed rats ... obesity, hypertension, and hyperglycemia. Patients with metabolic syndrome suffer chronic low inflammation state and oxidative ... Catechins and Proanthocyanidins Involvement in Metabolic Syndrome. Patanè, Giuseppe Tancredi; Putaggio, Stefano; Tellone, Ester ...

Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss. Journal of obesity & metabolic syndrome, [online] 29 ... 2023). FoodData Central. [online] Available at: https://fdc.nal.usda.gov/fdc-app.html#/food-details/171688/nutrients ... However, keep in mind that sticking to a diet high in fiber[21] and protein is generally a big help for weight loss.[22] Having ... Skipping breakfast is associated with overweight and obesity: A systematic review and meta-analysis. Obesity Research & ...

More specifically, resistance to diet-induced obesity can occur through the loss of PTPRD in AgRP neurons. When asprosin binds ... April 2021). Isales M, Zaidi C, Isales C (eds.). "Asprosin-neutralizing antibodies as a treatment for metabolic syndrome". ... A central mechanism of appetite regulation is via orexigenic AgRP neurons and anorexigenic POMC neurons in the arcuate nucleus ... Asprosin-induced hyperphagia and hepatic glucose production could therefore be mechanisms that drive development of metabolic ...

... prevented the diet-induced obesity and a variety of obesity-induced metabolic disorders, too. This chapter will be focused on ... Obesity is a heterogeneous disorder predisposing patients to a variety of diseases such as; metabolic syndrome, type 2 diabetes ... The predominance of central, viscerally deposited fat may alter the immunological, metabolic and endocrine milieu. Visceral ... including crude extracts and isolated compounds induce body weight reduction and prevent diet-induced obesity. Examples of ...

2 NAFLD is associated with obesity and features of metabolic syndrome, including hypertension, dyslipidemia, central adiposity ... Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α ... 6 Weight loss induced by diet and exercise has also been shown to be effective in resolving NASH and improving hepatic fibrosis ... Chronic Metabolic Diseases. Medical Research & Publication. * Information and Policy For Authors. For Reviewers. Article ...

"Yerba mate extract (Ilex paraguariensis) attenuates both central and peripheral inflammatory effects of diet-induced obesity in ... "Protective and ameliorative effects of maté (Ilex paraguariensis) on metabolic syndrome in TSOD mice." Phytomedicine. 2011 Dec ... "Yerba mate extract (Ilex paraguariensis) attenuates both central and peripheral inflammatory effects of diet-induced obesity in ... "Long-term dietary supplementation with yerba mate ameliorates diet-induced obesity and metabolic disorders in mice by ...

... and central obesity. Therefore, plant-derived flavonoid naringin is used for the treatment of metabolic syndrome due to its ... A high-fat diet is responsible for the development of metabolic syndrome both in humans as well as in animals. This syndrome is ... which further induces angiogenesis. Hence, due to excellent therapeutic properties, the demand for naringin is expected to rise ...

New studies are revealing how a high-fat diet could be making the cells of the intestinal lining more likely to become ... But what is a case study and why are they helpful? Read on to lear...... The prevalence of overweight and obesity was found to ... Yet, at least 300,000 deaths every year in... The present study conducted a systematic literature review to examine obesity ... this study provides a systematic review of studies focused on the association between obesity in adults... 39% of adults aged ...

The high-carbohydrate high-fat diet induced an impaired glucose tolerance, insulin resistance, obesity, elevated blood pressure ... Metabolic syndrome is the constellation of metabolic disorders such as central obesity, dyslipidaemia, insulin resistance, ... The prevalence of metabolic syndrome is increasing worldwide.. Diet is important in the development of metabolic syndrome ... To induce metabolic syndrome, young male Wistar rats were fed with a high-carbohydrate high-fat diet for 16 weeks while corn ...

These data further our understanding of the role of endocannabinoid signaling to promote not only diet-induced, but also, ... Our results show that sustained exposure to GCs produces obesity and metabolic syndrome through a peripheral endocannabinoid ... and metabolic processes through both central and peripheral pathways. The aim of this study was to determine the role of ... Obesity and associated metabolic disorders (e.g., cardiovascular disease and type 2 diabetes) are major public health concerns ...

Helpful in management of obesity and other Diseases: A Review, Shivam Vashist, Kamal, Pooja Rathi ... Overview of Obesity and Pharmacological Significance of Sita Ashoka (Saraca asoca) ... Despres JP, Lemieux I: Abdominal obesity and metabolic syndrome. Nature; 444: 881-887 [Google Scholar] [Cross Ref] ... Drug Induced Obesity. Several pharmacologic agents provoke obesity. Ex: Glucocorticosteroid, sulfonylurea (SU), and ...

Significant risk factors associated with GBD are age, female sex, obesity (especially central obesity), lipids, diet, parity, ... GBD appears to be strongly related to the metabolic syndrome (605552) and/or its major components, such as hyperinsulinism, ... andoral contraceptive-induced cholestasis (OCIC; see 614972). Genetic Heterogeneity of Gallbladder Disease Two major ... "metabolic stroke" (bilateral lacunar infarction of the basal ganglia during acute metabolic decompensation), pancreatitis, ...

... obesity_and_metabolic_syndrome_A_review/links/5a2562280f7e9b71dd078b10/Beneficial-effects-of-ginger-Zingiber-officinale-Roscoe- ... 2019). Weight loss effect of sweet orange essential oil microcapsules on obese SD rats induced by high-fat diet.. https:// ... 2017). Exploring pharmacological mechanisms of lavender (Lavandula angustifolia) essential oil on central nervous system ... 2018). Metabolic impairments and tissue disorders in alloxan-induced diabetic rats are alleviated by Salvia officinalis L. ...

Changes in gut microbiota control metabolic diet-induced obesity and diabetes in mice. Diabetes (2008) 57:1470-81. doi:10.2337/ ... The gut microbial community in metabolic syndrome patients is modified by diet. J Nutr Biochem (2015) 27:27-31. doi:10.1016/j. ... Differential effects of two fermentable carbohydrates on central appetite regulation and body composition. PLoS One (2012) 7: ... Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A (2007) 104:979-84. doi ...

... inflammatory response and metabolic pathways. Further IPA analysis demonstrated that the acute phase response signaling, NF-κB ... pellet and/or high-fat diet (HFD) for 12 weeks to mimic sustained estrogen stimulation and insulin resistance. ... Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic syndrome (MetS). The purpose is to assess the ... In our overall synthesis, we conclude that development of ovarian hyperandrogenism may be a central mechanism relating ...

Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central ... A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome ... Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet *M. Sörhede ... GIP prevents the development of diabetes and related metabolic abnormalities associated with genetically inherited obesity in ...

Methods: We searched the following databases up until January 2018: MEDLINE, EMBASE, Web of Science, and Cochrane Central ... was carried out to assess the influence of curcumin intake on weight among patients with metabolic syndrome and related ... we have found that curcumin intake among patients with metabolic syndrome and related disorders may be correlated with a ... we have found that curcumin intake among patients with metabolic syndrome and related disorders was correlated with a ...

of metabolic syndrome and is characterized by insulin resistance (Utzschneider &. Kahn, 2006), is treated by stevia ... diet, CD and WR diet, were fed with high-fat/cholesterol diets for eight weeks. The rats fed with CD exhibited higher weight ... Recent studies of obesity show that fat tissue fulfills an endocrine function by producing a variety of secreted proteins, ... Rather than the total amount of fat, central distribution of adipose tissue is very important in the pathophysiology of this ...

Finally, we evaluated the hypothesis that deficits in sympathetic input from the central clock located in the suprachiasmatic ... Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308, 1043-1045 (2005). ... Fish oil accelerates diet-induced entrainment of the mouse peripheral clock via GPR120. PLoS ONE 10, e0132472 (2015). ... The central clock in the SCN initially responds to light cues and functions to subsequently inhibit food anticipatory activity. ...

Association between modifiable lifestyle factors and inflammatory markers in patients with metabolic syndrome ... diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity. ... The metabolic syndrome. Lancet, 2005, 365(9468):1415-1428.. *Elk CM, Francis J. Central adiposity, systemic inflammation, and ... 21] have shown high saturated fatty acid intakes induced rising plasma levels of free saturated fatty acids, especially ...

Obesity - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version ... Exercise increases energy expenditure, basal metabolic rate, and diet-induced thermogenesis. Exercise also seems to regulate ... syndrome Serotonin Syndrome Serotonin syndrome is a potentially life-threatening condition resulting from increased central ... and metabolic syndrome Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess ...

... can be a helpful tool for managing emotional eating and promoting metabolic health. ... Ritchie, S. A., & Connell, J. M. C. (2007). The link between abdominal obesity, metabolic syndrome and cardiovascular disease. ... stress-induced cortisol secretion is consistently greater among women with central fat. Psychosomatic medicine, 62(5), 623-632. ... Mindfulness is a tool that can be used to improve many aspects of metabolic health. Other habits like diet, exercise, or sleep ...

Here we discuss the molecular mechanisms through which alimentary cues modulate metabolic, microbial and neuroendocrine ... Kroemer and colleagues discuss the mechanisms through which nutrition modulates metabolic, microbial and neuroendocrine ... Diet-induced obesity alters dendritic cell function in the presence and absence of tumor growth. J. Immunol. 189, 1311-1321 ( ... Obesity concurrent with metabolic syndrome appears to be more closely associated with cancer than is obesity concurrent with ...

Panchakarma has been used to treat allergies, asthma , arthritis, cancer, chronic fatigue syndrome , colitis, high cholesterol ... Due to poor diets , bad health habits, and other causes, digestion can be impaired, causing a toxic substance called ama to ... Panchakarma is based on central concepts of Ayurveda, which state that disease is caused by the build-up of toxic substances in ... Vamana uses herbal solutions or salt water to induce vomiting. This treatment is used for skin problems, asthma, diabetes, ...