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*  Diacylglycerol kinase
... (DGK, EC 2.7.1.107) is a lipid kinase that phosphorylates diacylglycerol (DAG) to generate phosphatidic ... Diacylglycerol kinase. Book title. Lipid signaling in plants. Pages (from-to). 107-114. Number of pages. 330. Publisher. ...
http://dare.uva.nl/search?metis.record.id=333503
*  Site-directed mutagenesis of the active site of diacylglycerol kinase α: calcium and phosphatidylserine stimulate enzyme...
Diacylglycerol kinases (DAGKs) catalyse ATP-dependent phosphorylation of sn-1,2-diacylglycerol that arises during stimulated ... Abbreviations used: DAG, diacylglycerol; DAGK, DAG kinase; HRP, horseradish peroxidase; OG, octylglucoside; PA, phosphatidic ... Site-directed mutagenesis of the active site of diacylglycerol kinase α: calcium and phosphatidylserine stimulate enzyme ... Site-directed mutagenesis of the active site of diacylglycerol kinase α: calcium and phosphatidylserine stimulate enzyme ...
http://www.biochemj.org/content/375/3/673
*  Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by...
Our data suggest that octadecadienoic acids and diacylglycerol synergistically induce platelet activation via protein kinase C ... Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by ... Seifert, Roland, Schächtele, C. und Schultz, Günter (1987) Activation of protein kinase C by cis- and trans-octadecadienoic ... Octadecadienoic acid-induced platelet activation was suppressed by the protein kinase C inhibitor, polymyxin B, but not by the ...
https://epub.uni-regensburg.de/23271/
*  ORBi: Browsing ORBi
Determination Of The Topology Of The Hydrophobic Segment Of Mammalian Diacylglycerol Kinase Epsilon In A Cell Membrane And Its ... The epsilon isoform of diacylglycerol kinase (DGKepsilon) is unique among mammalian DGKs in having a segment of hydrophobic ... The epsilon isoform of diacylglycerol kinase (DGKepsilon) is unique among mammalian DGKs in having a segment of hydrophobic ...
http://orbi.ulg.ac.be/browse?type=author&value=Decaffmeyer,%20Marc%20p079595
*  Patent US6015892 - Oligonucleotide modulation of protein kinase C - Google Patents
Compositions and methods are provided for the treatment, detection and diagnosis of diseases associated with protein kinase C ... New nucleic acid sequences are provided which encode 3' untranslated regions of human protein kinase C alpha polynucleotide ... Methods of treating conditions amenable to therapeutic intervention by modulating protein kinase C expression with an ... Compositions and methods are provided for the treatment and diagnosis of diseases associated with protein kinase C. ...
http://www.google.com.au/patents/US6015892
*  Characterization of phospholipase D activation by muscarinic receptors in human neuroblastoma SH-SY5Y cells
... is probably secondary to the protein kinase C activation that follows phospholipase C-mediated increase in diacylglycerols. ... Other kinases may be involved in the regulation since also a tyrosine kinase inhibitor decreased the phosphatidylethanol ... Other kinases may be involved in the regulation since also a tyrosine kinase inhibitor decreased the phosphatidylethanol ... 2-diacylglycerol. This indicates that phospholipase D contributes to the formation of 1,2-diacylglycerol after carbachol ...
https://lup.lub.lu.se/search/publication/1111182
*  Expression of tung tree diacylglycerol acyltransferase 1 in E. coli | BMC Biotechnology | Full Text
Diacylglycerol acyltransferases (DGATs) catalyze the final and rate-limiting step of triacylglycerol (TAG) biosynthesis in ... that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinases. Arch Biochem ... Expression of tung tree diacylglycerol acyltransferase 1 in E. coli. *Heping Cao1. , ... The plasmid pMBP-DGAT1-His was engineered to express the full-length tung tree (Vernicia fordii) type 1 diacylglycerol ...
https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-11-73
*  Recombinant Monoacylglycerol-O-acyltransferase 2 (MOGAT2) | RPH629Hu01 | Homo sapiens (Human) CLOUD-CLONE CORP.(CCC)
Diacylglycerol acyltransferase 2-like protein 5 , Products for research use only! ... Enzyme & Kinase. *Product No.RPH629Hu01. *Organism SpeciesHomo sapiens (Human) Same name, Different species. ... MGAT2; DGAT2L5; DC5; 2-Acylglycerol O-Acyltransferase 2; Diacylglycerol O-acyltransferase candidate 5; Diacylglycerol ...
http://www.cloud-clone.com/products/RPH629Hu01.html
*  Diacylglycerol kinase - Wikipedia
Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyzes the conversion of diacylglycerol (DAG) to ... Diacylglycerol Kinase at the US National Library of Medicine Medical Subject Headings (MeSH) EC 2.7.1.107 Molecular and ... Some Gram-positive bacteria also encode a soluble diacylglycerol kinase capable of reintroducing DAG into the phospholipid ... Smith RL, O'Toole JF, Maguire ME, Sanders CR (September 1994). "Membrane topology of Escherichia coli diacylglycerol kinase". J ...
https://en.wikipedia.org/wiki/Diacylglycerol_kinase
*  Diacylglycerol kinase (CTP dependent) - Wikipedia
Diacylglycerol kinase (CTP dependent) (EC 2.7.1.174, DAG kinase, CTP-dependent diacylglycerol kinase, diglyceride kinase) is an ... Diacylglycerol kinase Han, G.S.; O'Hara, L.; Carman, G.M.; Siniossoglou, S. (2008). "An unconventional diacylglycerol kinase ... Diacylglycerol kinase (CTP dependent) at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... "Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase". J. Biol. Chem. 283: 20443-20453. doi:10.1074/ ...
https://en.wikipedia.org/wiki/Diacylglycerol_kinase_(CTP_dependent)
*  NAD kinase/diacylglycerol kinase-like domain superfamily (IPR016064) | InterPro | EMBL-EBI
NAD kinase/diacylglycerol kinase-like domain superfamily (IPR016064). Short name: NAD/diacylglycerol_kinase_sf ... ATP-NAD kinase contains two domains, where domain 1 has an alpha/beta topology that is related in structure to the N-terminal ... ATP-NAD kinases (EC:2.7.1.23) catalyse the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as ... Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP.. J. Mol. Biol. 354 289-303 ...
http://www.ebi.ac.uk/interpro/entry/IPR016064
*  WikiGenes - DGKQ - diacylglycerol kinase, theta 110kDa
A diacylglycerol kinase is involved in the regulation of interleukin-2 synthesis in Jurkat T cells. Aussel, C., Pelassy, C., ... Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled ... Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin. Bregoli, L., Baldassare, J.J., Raben, D.M. J. ... Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus. Tabellini, G., Bortul, R., Santi, S., Riccio, M ...
https://www.wikigenes.org/e/gene/e/1609.html
*  DGKA - Diacylglycerol kinase alpha - Homo sapiens (Human) - DGKA gene & protein
Diacylglycerol kinase alphaImported. ,p>Information which has been imported from another database using automatic procedures.,/ ... tr,G3V4I3,G3V4I3_HUMAN Diacylglycerol kinase alpha (Fragment) OS=Homo sapiens OX=9606 GN=DGKA PE=1 SV=1 ... DAG_kinase_NInterPro annotation. ,p>Information which has been generated by the UniProtKB automatic annotation system, without ... IPR029477. DAG_kinase_typeI_N. IPR037607. DGK. IPR011992. EF-hand-dom_pair. ...
http://www.uniprot.org/uniprot/G3V4I3
*  Dgka - Diacylglycerol kinase alpha - Mus musculus (Mouse) - Dgka gene & protein
... initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. ... Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, ... "Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products.". Cipres A., Carrasco S., Merino E., ... "Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products.". Cipres A., Carrasco S., Merino E., ...
https://www.uniprot.org/uniprot/O88673
*  Human Metabolome Database: Showing Protein Diacylglycerol kinase alpha (HMDBP00233)
Showing Protein Diacylglycerol kinase alpha (HMDBP00233). IdentificationBiological propertiesGene propertiesProtein properties ... Involved in diacylglycerol kinase activity. Specific Function. Upon cell stimulation converts the second messenger ... Hart TC, Zhou J, Champagne C, Van Dyke TE, Rao PN, Pettenati MJ: Assignment of the human diacylglycerol kinase gene (DAGK) to ... Hart TC, Champagne C, Zhou J, Van Dyke TE: Assignment of the gene for diacylglycerol kinase (DAGK) to human chromosome 12. Mamm ...
http://www.hmdb.ca/proteins/HMDBP00233
*  Diacylglycerol kinases (DGK) Gene Family | HUGO Gene Nomenclature Committee
diacylglycerol kinase alpha. DAGK, DAGK1. DGK-alpha. 12q13.2. DGKB diacylglycerol kinase beta. DAGK2. KIAA0718, DGK, DGK-BETA. ... diacylglycerol kinase theta. DAGK4. DAGK, DAGK7. 4p16.3. DGKZ diacylglycerol kinase zeta. DAGK5, hDGKzeta, DGK-ZETA, DAGK6. ... Diacylglycerol kinase: Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyzes the conversion of ... Some Gram-positive bacteria also encode a soluble diacylglycerol kinase capable of reintroducing DAG into the phospholipid ...
https://www.genenames.org/cgi-bin/genefamilies/set/1178
*  Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor
Diacylglycerol is a physiological activator of PKC that can be removed by diacylglycerol kinase (DGK) activity. We found, in ... Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor. ... Epidermal growth factor receptor (EGFR) activation is negatively regulated by protein kinase C (PKC)signaling. Stimulation of ...
http://library.wur.nl/WebQuery/wurpubs/433446
*  dgkz, diacylglycerol kinase, zeta - Creative Biogene
DGKZ; diacylglycerol kinase, zeta; diacylglycerol kinase, zeta 104kDa; diacylglycerol kinase zeta; DAGK5; DAGK6; DGK ZETA; ... The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C ... hDGKzeta; DAG kinase zeta; diglyceride kinase zeta; DGK-ZETA; DAGK5, hDGKzeta, DGK-ZETA, DAGK6 ... Profiling ServicesKinase Screening & Profiling ServicesProtease Screening & Profiling ServicesNuclear Receptor Screening & ...
https://www.creative-biogene.com/symbolsearch_dgkz.html
*  Frontiers | Arachidonoyl-Specific Diacylglycerol Kinase ε and the Endoplasmic Reticulum | Cell and Developmental Biology
One enzyme responsible for PA synthesis is diacylglycerol kinase (DGK) that phosphorylates diacylglycerol (DG) to PA. DGK is ... that phosphorylates diacylglycerol (DG) to PA. DGK is composed of a family of enzymes with distinct features assigned to each ... One enzyme responsible for PA synthesis is diacylglycerol kinase (DGK) ... Van Horn, W. D., and Sanders, C. R. (2012). Prokaryotic diacylglycerol kinase and undecaprenol kinase. Annu. Rev. Biophys. 41, ...
https://www.frontiersin.org/articles/10.3389/fcell.2016.00132/full
*  Abstract A3: Enhanced effector responses in CAR-redirected CD8+ T cells deficient in diacylglycerol kinases. | Cancer Research
Abstract A3: Enhanced effector responses in CAR-redirected CD8+ T cells deficient in diacylglycerol kinases.. Matthew Riese, ... We tested CAR activity and function in T cells that lacked one or both lymphocyte-specific isoforms of diacylglycerol kinase ( ... Enhanced effector responses in CAR-redirected CD8+ T cells deficient in diacylglycerol kinases. [abstract]. In: Proceedings of ... Abstract A3: Enhanced effector responses in CAR-redirected CD8+ T cells deficient in diacylglycerol kinases. ...
http://cancerres.aacrjournals.org/content/73/1_Supplement/A3
*  Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem CAS 120166-69-0 | 266788
... controls the biological activity of Diacylglycerol KInase. This small molecule/inhibitor is primarily used for Phosphorylation ... The Diacylglycerol Kinase Inhibitor II, also referenced under CAS 120166-69-0, ... Diacylglycerol Kinase. Primary Target IC,sub,50,/sub,. 300 nM and 120 nM against diacylglycerol kinase in isolated platelet ... Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem. 266788 Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 ...
http://www.emdmillipore.com/CA/en/product/Diacylglycerol-Kinase-Inhibitor-II-CAS-120166-69-0-Calbiochem,EMD_BIO-266788
*  Overexpression of Diacylglycerol Kinase η Enhances Gαq-Coupled G Protein-Coupled Receptor Signaling | Molecular Pharmacology
diacylglycerol. DGK. diacylglycerol kinase. DTT. DL-dithiothreitol. EGFR. epidermal growth factor receptor. GFP. green ... 2012) Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor. Int J Biochem Cell Biol ... 2006) Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Proc Natl Acad Sci ... 2010) Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and ...
http://molpharm.aspetjournals.org/content/85/5/800
*  Functional and Physical Interaction of Diacylglycerol Kinase ζ with Protein Kinase Cα Is Required for Cerebellar Long-Term...
2003b) Association of diacylglycerol kinase zeta with protein kinase C alpha: spatial regulation of diacylglycerol signaling. J ... 2003a) Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta. J Biol Chem 278:39542-39547, ... Diacylglycerol kinase (DGK) metabolizes diacylglycerol (DAG) to phosphatidic acid (PA), which is the major pathway to terminate ... Here, we analyzed the role of diacylglycerol kinase ζ (DGKζ), a kinase that physically interacts with PKCα as well as ...
http://www.jneurosci.org/content/35/46/15453
*  Cardiac-Specific Overexpression of Diacylglycerol Kinase ζ Prevents Gq Protein-Coupled Receptor Agonist-Induced Cardiac...
Association of diacylglycerol kinase ζ with protein kinase C α: spatial regulation of diacylglycerol signaling. J Cell Biol. ... Diacylglycerol functions as a potent activator of protein kinase C (PKC) and is catalyzed by diacylglycerol kinase (DGK) to ... Diacylglycerol kinase ε, but not ζ, selectively removes polyunsaturated diacylglycerol, inducing altered protein kinase C ... Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions. J Biol Chem. 1999; 274: 11447-11450. ...
http://circ.ahajournals.org/content/113/1/60
*  Frontiers | Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update | Cell and...
Ten mammalian diacylglycerol kinase (DGK) isozymes (alpha-kappa) have been identified to date. Our previous review noted that ... Ten mammalian diacylglycerol kinase (DGK) isozymes (alpha-kappa) have been identified to date. Our previous review noted that ... 2013). Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase ... Kai, M., Yasuda, S., Imai, S., Toyota, M., Kanoh, H., and Sakane, F. (2009). Diacylglycerol kinase α enhances protein kinase Cζ ...
https://www.frontiersin.org/articles/10.3389/fcell.2016.00082/full