Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials. Trinidad-Calderón PA, Varela-Chinchilla CD, ...
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The response rate of topotecan, as a second-line chemotherapeutic drug for small cell lung cancer, is ~20%. DNA/RNA helicase SLFN11 (schlafen family member 11), a member of the Schlafen (SLFN) family, is a crucial determinant of response to many DNA damaging agents, expression of SLFN11 tends to aug …
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Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials. Trinidad-Calderón PA, Varela-Chinchilla CD, ...
... whereas emesis is caused by the action of the depsipeptide toxin cereulide. T … ... whereas emesis is caused by the action of the depsipeptide toxin cereulide. The recently identified cereulide synthetase genes ...
A survey in eight European countries, including 13 hospitals, of vancomycin-resistant enterococci (VRE) in at-risk hospital wards (such as the ICU and the haematology ward) was performed in 2001, and the in vitro susceptibility of the isolates ramoplanin and other drugs was tested. A total of 1314 n …
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T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular ... Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a ...
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... depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the histone deacetylase ... PURPOSE Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the ...
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Recent progress of the synthetic studies of biologically active marine cyclic peptides and depsipeptides. Hamada Y, Shioiri T. ...
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