Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action - PubMed
Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials. Trinidad-Calderón PA, Varela-Chinchilla CD, ...
Emetic toxin formation of Bacillus cereus is restricted to a single evolutionary lineage of closely related strains - PubMed
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Bryostatin-1 Decreases HIV-1 Infection and Viral Production in Human Primary Macrophages - PubMed
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Romidepsin treatment for relapsed or refractory peripheral and cutaneous T-cell lymphoma: Real-life data from a national...
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Bacillus cereus-induced food-borne outbreaks in France, 2007 to 2014: epidemiology and genetic characterisation - PubMed
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FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11 - PubMed
The response rate of topotecan, as a second-line chemotherapeutic drug for small cell lung cancer, is ~20%. DNA/RNA helicase SLFN11 (schlafen family member 11), a member of the Schlafen (SLFN) family, is a crucial determinant of response to many DNA damaging agents, expression of SLFN11 tends to aug …
The Search for 'Evolution-Proof' Antibiotics - PubMed
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Multicenter phase 2 study of romidepsin plus lenalidomide for previously untreated peripheral T-cell lymphoma - PubMed
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Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action - PubMed
Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials. Trinidad-Calderón PA, Varela-Chinchilla CD, ...
Toxin gene profiling of enterotoxic and emetic Bacillus cereus - PubMed
... whereas emesis is caused by the action of the depsipeptide toxin cereulide. T … ... whereas emesis is caused by the action of the depsipeptide toxin cereulide. The recently identified cereulide synthetase genes ...
European survey of vancomycin-resistant enterococci in at-risk hospital wards and in vitro susceptibility testing of ramoplanin...
A survey in eight European countries, including 13 hospitals, of vancomycin-resistant enterococci (VRE) in at-risk hospital wards (such as the ICU and the haematology ward) was performed in 2001, and the in vitro susceptibility of the isolates ramoplanin and other drugs was tested. A total of 1314 n …
Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma -...
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Cereulide Synthetase Acquisition and Loss Events within the Evolutionary History of Group III Bacillus cereus Sensu Lato...
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Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable...
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Interference of CREB-dependent transcriptional activation by expanded polyglutamine stretches--augmentation of transcriptional...
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Phase 1 results from a study of romidepsin in combination with gemcitabine in patients with advanced solid tumors - PubMed
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Romidepsin treatment for relapsed or refractory peripheral and cutaneous T-cell lymphoma: Real-life data from a national...
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Reactivation of DNA viruses in association with histone deacetylase inhibitor therapy: a case series report - PubMed
T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular ... Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a ...
Results from a pivotal, open-label, phase II study of romidepsin in relapsed or refractory peripheral T-cell lymphoma after...
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Responses to romidepsin in patients with cutaneous T-cell lymphoma and prior treatment with systemic chemotherapy - PubMed
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The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies -...
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The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies -...
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A phase II study on the role of gemcitabine plus romidepsin (GEMRO regimen) in the treatment of relapsed/refractory peripheral...
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Results from a pivotal, open-label, phase II study of romidepsin in relapsed or refractory peripheral T-cell lymphoma after...
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Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T...
... depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the histone deacetylase ... PURPOSE Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the ...
Romidepsin (Istodax) for cutaneous T-cell lymphoma - PubMed
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Combination of romidepsin with cyclophosphamide, doxorubicin, vincristine, and prednisone in previously untreated patients with...
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Total synthesis of halipeptins A and D and analogues - PubMed
Recent progress of the synthetic studies of biologically active marine cyclic peptides and depsipeptides. Hamada Y, Shioiri T. ...
Romidepsin in relapsed/refractory T-cell lymphomas: Italian experience and results of a named patient program - PubMed
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Epstein-Barr virus reactivation in extranodal natural killer/T-cell lymphoma patients: a previously unrecognized serious...
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