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*  CNS demyelinating autoimmune diseases - Wikipedia
CNS demyelinating autoimmune diseases are autoimmune diseases which primarily affect the central nervous system. Examples ... A wider group of diseases which includes also the non-autoimmune demyelinating diseases. Demyelinating diseases - Group ... Transverse myelitis Neuromyelitis optica Idiopathic inflammatory demyelinating diseases - ...
https://en.wikipedia.org/wiki/CNS_demyelinating_autoimmune_diseases
*  Demyelinating Autoimmune Diseases, CNS; Autoimmune Demyelinating Diseases, Central Nervous System; Spinal Cord Demyelinating...
CNS; Autoimmune Demyelinating Diseases, Central Nervous System; Spinal Cord Demyelinating Autoimmune Diseases. On-line free ... Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms ... Demyelinating Autoimmune Diseases, CNS (Autoimmune Demyelinating Diseases, Central Nervous System; Spinal Cord Demyelinating ... "Demyelinating Autoimmune Diseases, CNS"Drugs, active principles and "Demyelinating Autoimmune Diseases, CNS"Medicinal plants ...
http://lookfordiagnosis.com/mesh_info.php?term=Demyelinating+Autoimmune+Diseases%2C+CNS&lang=1
*  Autoimmune Gliopathies and CNS Demyelinating Disease [Webinar] - Insights
CNS) inflammatory autoimmune demyelinating diseases for which a specific antigen has been identified-the astrocytic water ... Describe the evolving spectrum of biomarker-defined inflammatory CNS demyelinating diseases.. *Recognize the clinical utility ... unifies a spectrum of immunotherapy-responsive autoimmune inflammatory CNS disorders termed, "autoimmune GFAP astrocytopathy" ... This webinar will provide an overview of novel biomarker discoveries and advances being made in the study of autoimmune ...
https://news.mayomedicallaboratories.com/2018/01/12/autoimmune-gliopathies-cns-demyelinating-disease-webinar/
*  MATRIX: Measuring Neutralizing Antibodies in the Patients Treated With Interferon Beta 1a IM, in Mexico and Colombia - Full...
Demyelinating Autoimmune Diseases, CNS. Autoimmune Diseases of the Nervous System. Nervous System Diseases. Demyelinating ... Autoimmune Diseases. Immune System Diseases. Antibodies. Interferon-beta. Interferon beta-1a. Antibodies, Blocking. Interferons ... The IFN beta 1a IM (Avonex or Jumtab) treatment should be the first disease modifying treatment ... No limitation of age, EDSS or other disease parameters will be applied. ...
https://clinicaltrials.gov/ct2/show/NCT01556685
*  Immunogenicity and Safety Study of Serum-Free Avonex - Full Text View - ClinicalTrials.gov
Demyelinating Autoimmune Diseases, CNS. Autoimmune Diseases of the Nervous System. Nervous System Diseases. Demyelinating ... Autoimmune Diseases. Immune System Diseases. Interferons. Interferon-beta. Interferon beta-1a. Antineoplastic Agents. Antiviral ... and/or other major disease that would preclude therapy with interferon beta. ...
https://clinicaltrials.gov/ct2/show/NCT00912860?term=biogen&spons=biogen&rank=20
*  Efficacy and Safety of Ofatumumab Compared to Teriflunomide in Patients With Relapsing Multiple Sclerosis - Full Text View -...
Demyelinating Autoimmune Diseases, CNS. Autoimmune Diseases of the Nervous System. Nervous System Diseases. Demyelinating ... Autoimmune Diseases. Immune System Diseases. Ofatumumab. Antibodies, Monoclonal. Antineoplastic Agents. Immunologic Factors. ... Condition or disease Intervention/treatment Phase Relapsing Multiple Sclerosis Drug: Ofatumumab subcutaneous injection Drug: ... Disease duration of more than 10 years in patients with an EDSS score of 2 or less ...
https://www.clinicaltrials.gov/ct2/show/NCT02792218
*  Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS) - Full Text View - ClinicalTrials.gov
Demyelinating Autoimmune Diseases, CNS. Autoimmune Diseases of the Nervous System. Nervous System Diseases. Demyelinating ... Autoimmune Diseases. Immune System Diseases. Thioctic Acid. Antioxidants. Molecular Mechanisms of Pharmacological Action. ... Current major disease or disorder other than MS (such as cancer, kidney, heart or lung disease, post-traumatic stress disorder ... Condition or disease Intervention/treatment Phase Multiple Sclerosis, Chronic Progressive Drug: lipoic acid Drug: Placebo Phase ...
https://www.clinicaltrials.gov/ct2/show/study/NCT01188811?term=NCT01188811&view=record
*  MedGen for PubMed (Select 22807325) - MedGen - NCBI
Demyelinating Autoimmune Diseases, CNS. Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the ... Autoimmune Nervous System Disorder. A disorder characterized by the degeneration of the nervous system due to autoimmunity. ... Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. In neuromyelitis ... Eye disease. A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, ...
https://www.ncbi.nlm.nih.gov/medgen?LinkName=pubmed_medgen&from_uid=22807325
*  Ophthalmology and Visual Science Listigns | Yale School of Medicine
Adie Syndrome; Demyelinating Autoimmune Diseases, CNS; Horner Syndrome; Intracranial Hypertension; Ocular Motility Disorders; ... Diabetic Retinopathy; France; Germany; Macular Degeneration; Ophthalmology; Portugal; Retinal Detachment; Retinal Diseases; ... Associate Professor of Epidemiology (Chronic Diseases) and of Ophthalmology and Visual Science ...
http://medicine.yale.edu/intranet/facultybydept/opthalfac.aspx
*  A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)
Neuromyelitis optica (NMO) is a severe demyelinating disease that selectively involves the optic nerves and the spinal cord but ... Neuromyelitis Optica, Myelitis, Transverse, Demyelinating Autoimmune Diseases, CNS, Autoimmune Diseases of the Nervous System ... A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease). Trial Phase:. Phase 4. ... Systemic diseases such as lupus, Sjogren's syndrome, anti-phospholipid antibody. syndrome, sarcoidosis, rheumatoid arthritis, ...
http://www.knowcancer.com/cancer-trials/NCT00304291/
*  Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-β Therapy in Multiple Sclerosis | The Journal of...
Multiple sclerosis (MS) is a demyelinating autoimmune disease of the CNS and a leading cause of lasting neurologic disabilities ... Health and Labor Sciences Research Grants for Research on Intractable Diseases from the Ministry of Health, Labor, and Welfare ... Sema4A plays critical roles in T cell activation and Th1 differentiation during the course of experimental autoimmune ...
http://www.jimmunol.org/content/early/2012/04/09/jimmunol.1102023
*  Validation Results With Nejm Articles - DNAHelix.org
Demyelinating Autoimmune Diseases, CNS. 11407. 17660530 Risk alleles for multiple sclerosis identified by a genomewide study.. ... Demyelinating Autoimmune Diseases, CNS. 11412. 17660530 Risk alleles for multiple sclerosis identified by a genomewide study.. ... Demyelinating Autoimmune Diseases, CNS. 11457. 17660530 Risk alleles for multiple sclerosis identified by a genomewide study.. ... Demyelinating Autoimmune Diseases, CNS. 11442. 17660530 Risk alleles for multiple sclerosis identified by a genomewide study.. ...
http://dnahelix.wikidot.com/validation-results-with-nejm-articles
*  Grand Rounds
... - Tolerogenic Vaccination as a Myelin-Specific Therapy for Autoimmune Demyelinating Disease of the CNS Feb 02, ... Grand Rounds - Tolerogenic Vaccination as a Myelin-Specific Therapy for Autoimmune Demyelinating Disease of the CNS - Read More ... "Tolerogenic Vaccination as a Myelin-Specific Therapy for Autoimmune Demyelinating Disease of the CNS" ... Grand Rounds - Autoimmune Related Epilepsies Mar 23, 2017 from 08:00 AM to 09:00 AM - CG222, Sanofi-Aventis Conference Center, ...
http://www.med.unc.edu/neurology/education-and-training/grand-rounds-2
*  Frontiers | The Dopaminergic System in Autoimmune Diseases | Immunology
We propose models that may underlie key roles of dopamine and its receptors in autoimmune diseases. ... We propose models that may underlie key roles of dopamine and its receptors in autoimmune diseases. ... and in inflamed tissues of patients with inflammatory bowel diseases or rheumatoid arthritis. The distorted expression of DARs ... and in inflamed tissues of patients with inflammatory bowel diseases or rheumatoid arthritis. The distorted expression of DARs ...
https://www.frontiersin.org/articles/10.3389/fimmu.2014.00117/full
*  IL-10 Modulates Th17 Pathogenicity during Autoimmune Diseases | Open Access Journals
... however dysregulated immune response may lead to inflammatory or autoimmune diseases. Elevate.. ... which is a chronic autoimmune demyelinating disease in CNS characterized by the infiltration of inflammatory cells, including ... Innate immunity and autoimmune diseases. The development of Th17 cells and Th17-associated autoimmune diseases are influenced ... Segal BM (2010) Th17 cells in autoimmune demyelinating disease. Semin Immunopathol 32: 71-77. ...
https://www.omicsonline.org/open-access/il10-modulates-th17-pathogenicity-during-autoimmune-diseases-2155-9899-1000400.php?aid=69646
*  Frontiers | Type II NKT Cells: An Elusive Population With Immunoregulatory Properties | Immunology
Here, we review current knowledge on type II NKT cells and their functions in different disease settings and how these cells ... Here, we review current knowledge on type II NKT cells and their functions in different disease settings and how these cells ... autoimmunity and infectious diseases. Based on their T cell receptor (TCR) expression, NKT cells are divided into two subsets, ... autoimmunity and infectious diseases. Based on their T cell receptor (TCR) expression, NKT cells are divided into two subsets, ...
https://www.frontiersin.org/articles/10.3389/fimmu.2018.01969/full
*  Multiple Sclerosis Research: Another new model for monitoring immune effects of MS
Multiple sclerosis is a demyelinating autoimmune disease of the CNS. Its animal model experimental autoimmune encephalomyelitis ... Thus, this model of myelin-induced CNS inflammation by human T cells may allow testing of new human-specific therapeuticals for ... To investigate human immune responses against myelin antigens in vivo we established a new subclinical experimental autoimmune ... Furthermore, immunized animals developed subclinical CNS inflammation with infiltrating CD4+ and CD8+ T cells and production of ...
http://multiple-sclerosis-research.blogspot.com/2013/05/another-new-model-for-monitoring-immune.html
*  Research
TNFR2 Deficiency Acts in Concert with Gut Microbiota to Precipitate Sex-biased Spontaneous CNS Demyelinating Autoimmune Disease ... Paradoxically, anti-TNF therapeutics exacerbate CNS demyelinating autoimmune diseases such as multiple sclerosis (MS), ... TNFR2 Deficiency Acts in Concert with Gut Microbiota to Precipitate Sex-biased Spontaneous CNS Demyelinating Autoimmune Disease ... antagonists are beneficial to patients with inflammatory autoimmune diseases, including Crohn's disease, rheumatoid arthritis, ...
http://mumc.missouri.edu/research/
*  New Tests | ARUP Laboratories
Test Number Test Name Effective Date 4/17/2019 3001409 Immunobullous Disease Panel, Epithelial Antibody Screening Panel 3001410 ... Autoimmune CNS Demyelinating Disease Reflexive Panel. 3001311. BCL6 (3q27) Gene Rearrangement by FISH. ...
https://www.aruplab.com/testing/new-tests
*  JCI - CNS-resident classical DCs play a critical role in CNS autoimmune disease
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system (CNS), ... CNS-resident classical DCs play a critical role in CNS autoimmune disease. ... CNS-resident classical DCs play a critical role in CNS autoimmune disease. ... cDCs expanded in the meninges and CNS parenchyma in association with disease progression. Selective depletion of cDCs led to a ...
https://www.jci.org/articles/view/123708/figure/1
*  Student Conference Medical Engineering Science 2013 | Publish your master's thesis, bachelor's thesis, essay or term paper ...
Multiple Sclerosis (MS) is an autoimmune demyelinating disease occurring in the central nervous system (CNS). It is chronic, ... Osteoporosis is a skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue, with a ... It helps to determine the spread or progression of certain lung diseases and is thus mandatory for therapeutic monitoring. ... These treatments are evaluated monitoring the progress of the disease during clinical trials. Magnetic resonance imaging (MRI) ...
https://www.grin.com/document/210732
*  Lipopolysaccharide - Wikipedia
"Molecular mimicry as an inducing trigger for CNS autoimmune demyelinating disease". Immunol. Rev. 245 (1): 227-38. doi:10.1111/ ... The molecular mimicry of some LOS molecules is thought to cause autoimmune-based host responses, such as flareups of multiple ... "Association of lipopolysaccharide-binding protein and coronary artery disease in men". J. Am. Coll. Cardiol. 50 (1): 25-31. doi ... organisms which cause gastrointestinal disease in humans, and Haemophilus ducreyi which causes chancroid. Certain C. jejuni LPS ...
https://en.wikipedia.org/wiki/Lipopolysaccharide
*  Anti-NMDA-Receptor Encephalitis | ARUPConsult Lab Test Selection
Anti-NMDA receptor encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease associated with anti- ... Aid in diagnosis of CNS demyelinating disease or autoimmune encephalitis. The presence of myelin oligodendrocyte glycoprotein ( ... Autoimmune Neurologic Disease Reflexive Panel 2013944. Method: Semi-Quantitative Indirect Fluorescent Antibody/Qualitative ... Anti-N-methyl-D-aspartate (NMDA) encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease ...
https://arupconsult.com/content/n-methyl-d-aspartate-nmda-type-glutamate-receptor-autoantibody-disorders
*  Plus it
... myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113:3190-3197, ... monocytes into the CNS may be disease-model specific as some models (Huang et al., 2006) are noticeably absent of this ... 2010) Tickets to the brain: role of CCR2 and CX3CR1 in myeloid cell entry in the CNS. J Neuroimmunol 224:80-84, doi:10.1016/j. ... 2011) Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci 14:1227-1235, doi:10.1038/nn.2923, ...
http://www.jneurosci.org/content/35/2/748
*  The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood | The Journal of...
Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. ... Interestingly, during CNS inflammation, monocytes that infiltrate the CNS maintained their signature chemokine receptor ... experimental autoimmune encephalomyelitis. IB4. isolectin-B4. MHC-II. MHC class II. ON. overnight. RFP. red fluorescent protein ... In the naive CNS of Cx3cr1+/gfp and Cx3cr1gfp/gfp mice, CX3CR1 transcription unit was exclusively active in microglial cells, ...
http://www.jimmunol.org/content/188/1/29.full