The model genome of Arabidopsis thaliana contains a DEAD-box RNA helicase family (RH) of 58 members, i.e. almost twice as many ... DEAD-box RNA helicases in Arabidopsis thaliana: establishing a link between quantitative expression, gene structure and ... The master regulatory element in the definition of the transcript level is the simultaneous presence of a TATA-box and an ... as long as a characteristic TATA-box is present. Our work on the housekeeping AtRHs suggests a scenario for the evolution of ...
We have previously demonstrated that the DEAD-box RNA helicase p68 is an important regulator of gene expression [1, 2], whilst ... Wilson BJ, Bates GJ, Nicol SM, Gregory DJ, Perkins ND, Fuller-Pace FV: The p68 and p72 DEAD box RNA helicases interact with ... Coactivation of estrogen receptor alpha by the DEAD-box RNA helicases p68 and p72 and its role in breast cancer. ... A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation ...
DExD/H-box RHs are found in most organisms and play critical roles in a variety of RNA-involved cellular events. In human and ... DExD/H-box RHs are found in most organisms and play critical roles in a variety of RNA-involved cellular events. In human and ... We also describe the overall function of the DExD/H-box RH family in ribosome biogenesis based on data from human and yeast. ... We also describe the overall function of the DExD/H-box RH family in ribosome biogenesis based on data from human and yeast. ...
... a DEAD-box protein also known as p68 RNA helicase.. The DEAD-box family of RNA helicases is defined by a conserved Asp-Glu-Ala- ... and helicase activity (18). Many cellular functions of DEAD-box RNA helicases have been attributed to RNA duplex unwinding and ... DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell ... DEAD-box proteins: the driving forces behind RNA metabolism. Nat Rev Mol Cell Biol 2004;5:232-41. ...
TgHoDI is a newly identified member of the DEAD-box RNA helicase family in Toxoplasma gondii. This study was aimed at ... Furthermore, colocalization studies of TgHoDI with PABPC3 identified these proteins as components of RNA aggregates known as ... RNA helicases are vital components of various pathways for post-transcriptional gene regulation. ... TgHoDI is a newly identified member of the DEAD-box RNA helicase family in Toxoplasma gondii. This study was aimed at ...
Tobacco VDL gene encodes a plastid DEAD box RNA helicase and is involved in chloroplast differentiation and plant morphogenesis ... Home» Tobacco VDL gene encodes a plastid DEAD box RNA helicase and is involved in chloroplast differentiation and plant ... The predicted 53-kD product belongs to the DEAD box RNA helicase family. In the homozygous vdl mutant, T-DNA insertion resulted ... Amino Acid Sequence ; Base Sequence ; Cell Differentiation ; Chloroplasts ; Cloning, Molecular ; DEAD-box RNA Helicases ; DNA ...
摘要】:DEAD-box (DDX) helicases are vital for the recognition of RNA and metabolism and are critical for the initiation of ... 科研成果: "The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus". 发布 ... After viral infection, DDX46 recruited ALKBH5, an eraser of the RNA modification N6-methyladenosine (m6A), via DDX46s DEAD ... "The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus"。文章链接:https ...
The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans. ... The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans. ... In this study, a virulence-associated DEAD-box RNA helicase-encoding gene (VAD1) was isolated from a mutant defective in the ... Northern blot analysis of RNA from the indicated cells incubated for 3 hours in asparagine media with or without glucose. (. B ...
Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of ... box_helicase_dom. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR027417. P-loop_NTPase. IPR014014. RNA_helicase_DEAD_Q_ ... box_helicase_dom. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR027417. P-loop_NTPase. IPR014014. RNA_helicase_DEAD_Q_ ... DEAD-box ATP-dependent RNA helicase CshBUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ...
Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP ... DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved. Members of this family of ... DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved. Members of this family of ... Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP. *DOI: 10.2210/pdb3FE2/pdb ...
... we have identified a member of the DEAD-box protein (DBP) family, the DEAD-box RNA helicase and mRNA export factor Dbp5, as a ... DEAD-box RNA helicases are found in almost all organisms and function in many fundamental steps in the life of RNA molecules, ... The DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination Message Subject. (Your Name) has forwarded a page to you ... The DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination. By Thomas Gross, Anja Siepmann, Dorotheé Sturm, Merle ...
In this study, a virulence-associated DEAD-box RNA helicase-encoding gene (VAD1) was isolated from a mutant defective in … ... The DEAD-box RNA helicase Vad1 regulates multiple virulence-associated genes in Cryptococcus neoformans J Clin Invest. 2005 Mar ... In this study, a virulence-associated DEAD-box RNA helicase-encoding gene (VAD1) was isolated from a mutant defective in the ...
Bacillus subtilis possesses four DEAD-box RNA helicases (DBRH) genes, cshA, cshB, deaD/yxiN, and yfmL that make a good case to ... Our findings suggest that the long time divergence between DEAD-box RNA helicase genes has resulted in specialized activities ... They possess the highly conserved N-terminal catalytic domain core common to RNA helicases, but different carboxy-terminal ends ... They possess the highly conserved N-terminal catalytic domain core common to RNA helicases, but different carboxy-terminal ends ...
A DEAD-box RNA helicase, RH8, is critical for regulation of ABA signalling and the drought stress response via inhibition of ... In the present study, we used a yeast 2-hybrid (Y2H) screening analysis to identify the DEAD-box RNA helicase RH8, which ...
... Cell Rep. 2014 Jun 26;7(6):1887-99. doi: ... 2 Memorial Sloan-Kettering Cancer Center, 415 E. 68(th) Street, Box 373, New York, NY 10065, USA. ... DEAD-box RNA Helicases / antagonists & inhibitors * DEAD-box RNA Helicases / metabolism* * Disease Progression ...
Introduction: The DEAD box RNA helicase DDX3X (DDX3) has been demonstrated to have a pro-oncogenic role in breast cancer. Thus ... Abstract 3812: Targeting BRCA1-deficient breast cancer by inhibition of the DEAD box RNA helicase DDX3X. Marise R. Heerma van ... Targeting BRCA1-deficient breast cancer by inhibition of the DEAD box RNA helicase DDX3X. [abstract]. In: Proceedings of the ... Abstract 3812: Targeting BRCA1-deficient breast cancer by inhibition of the DEAD box RNA helicase DDX3X ...
We demonstrate that the DEAD-box RNA helicase DDX6 re-localizes to the site of foamy virus assembly where viral RNA and Gag ... AriumiYKurokiMKiAbeDansakoHIkedaM 2007 DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication. J Virol 81 ... The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome Download PDF České info ... DDX6 has RNA-dependent ATPase and ATP-dependent RNA helicase activities that are determined by the highly conserved DEAD box as ...
ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 ... box_helicase_dom. IPR014001 Helicase_ATP-bd. IPR001650 Helicase_C. IPR027417 P-loop_NTPase. IPR014014 RNA_helicase_DEAD_Q_motif ... box_helicase_dom. IPR014001 Helicase_ATP-bd. IPR001650 Helicase_C. IPR027417 P-loop_NTPase. IPR014014 RNA_helicase_DEAD_Q_motif ... The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. ...
Several RNA helicases from the DEAD-box protein family and Suv3, an RNA helicase forming its own family most closely related to ... as in the case of the short DEAD-box protein eIF4A [9], the specificity of most DEAD-box RNA helicases is given by the N- and/ ... including the DEAD-box family. DEAD-box proteins can clearly be distinguished from the other RNA helicases based on the ... 1996) A DEAD-box RNA helicase in the Escherichia coli RNA degradosome. Nature 381, 169-172 doi:10.1038/381169a0. ...
DEAD/DEAH box helicases are proteins, and are putative RNA helicases. They are implicated in a number of cellular processes ... This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as ... a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.The DHX9 ... Zhang S, Grosse F (Apr 1997). "Domain structure of human nuclear DNA helicase II (RNA helicase A)". The Journal of Biological ...
Flaviviruses are positive-sense RNA viruses, and many are important human pathogens. Nonstructural protein 2B and 3 of the ... From unwinding to clamping - the DEAD box RNA helicase family. Nat Rev Mol Cell Biol, 12: 505-516.PubMedGoogle Scholar ... The RNA helicase, nucleotide 5′-triphosphatase, and RNA 5′-triphosphatase activities of Dengue virus protein NS3 are Mg2+- ... The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 ...
Buy the Other Book RNA helicases by Eckhard Jankowsky at Indigo.ca, Canadas largest bookstore. + Get Free Shipping on books ... Oxygen Isotopic Exchange Probes of ATP Hydrolysis by RNA Helicases. *Conformational Changes of DEAD-box Helicases Monitored by ... Analysis of DEAD-box Proteins in mRNA Export. *Biochemical Characterization of the RNA Helicase UPF1 Involved in Nonsense- ... RNA Catalysis as a Probe for Chaperone Activity of DEAD-box Helicases ...
Forty-six Nullbasic-binding proteins were identified by mass spectrometry including the DEAD-box RNA helicase, DDX1. To ... was used to further define the complex mechanisms involved in the Rev-dependent nuclear export of the 9 kb and 4 kb viral RNAs ... Although HIV-1 does not encode for an RNA helicase, a number of cellular DEAD-box RNA helicases, including DDX1, DDX3, DDX5/p68 ... DEAD (Asp - Glu - Ala - Asp)-box helicases form the largest family of RNA helicases and are conserved in bacteria, archaea and ...
Using bioinformatics, 33 putative DEAD-box RNA helicases exhibiting conserved motifs that characterize helicases of this family ... Vasa, a member of the ATP-dependent DEAD-box RNA helicase family, is a prototypic marker of primordial germ cells and the germ ... andSmvlg3-were members of the Vasa/PL10 DEAD-box subfamily. Transcripts encoding Smvlg1,Smvlg2, and Smvlg3 were cloned from ... Moreover, three of the helicases exhibited vasa-like sequences; phylogenetic analysis confirmed the three vasa-like genes- ...
Mouse monoclonal RNA Helicase A antibody [2274D5a]. Validated in WB, Dot and tested in Human. Immunogen corresponding to ... Belongs to the DEAD box helicase family. DEAH subfamily.. Contains 2 DRBM (double-stranded RNA-binding) domains.. Contains 1 ... Anti-RNA Helicase A antibody [2274D5a]. See all RNA Helicase A primary antibodies. ... Protein - Recombinant Human RNA Helicase A protein (ab114300) WB, ELISA, SDS-PAGE ...