... cytoskeletal remodelling and tight junction protein expression and localisation have also been the focus of this thesis. ... reperfusion-evoked modulation of cytoskeletal remodelling, tight junction proteins and oxidative stress in human brain ... modulation of tight junction proteins and the induction of oxidative stress. Recently, the overactivities of protein kinase C ( ... A marked rise in the protein expressions of claudin-5 and β-catenin observed after OGD (20 hours) alone and followed by ...