Ligand binding of safrole to cytochrome P-450.  - Surrey Research Insight Open AccessLigand binding of safrole to cytochrome P-450. - Surrey Research Insight Open Access

... is converted by the microsomal mono-oxygenase system to a reactive intermediate which interacts with cytochrome P-450 to form a ... Delaforge, M, Ioannides, C and Parke, DV (1980) Ligand binding of safrole to cytochrome P-450. Arch Toxicol Suppl, 4. pp. 45-48 ... Animals, Binding, Competitive, Cytochrome P-450 Enzyme System, Dioxoles, In Vitro Techniques, Ligands, Male, Methylcholanthrene ...
more infohttp://epubs.surrey.ac.uk/823390/

The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in...The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in...

T1 - The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in ... The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in ... The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in ... The orphan nuclear receptor, liver receptor homolog-1, regulates cholesterol side-chain cleavage cytochrome P450 enzyme in ...
more infohttps://utsouthwestern.pure.elsevier.com/en/publications/the-orphan-nuclear-receptor-liver-receptor-homolog-1-regulates-ch

WHO HQ Library catalog ›

    Results of search for su:{Cytochrome P-450 enzyme system.}WHO HQ Library catalog › Results of search for 'su:{Cytochrome P-450 enzyme system.}'

Results of search for su:{Cytochrome P-450 enzyme system.} Refine your search. *Availability * Limit to currently available ... The role of cytochrome P-450 and p-glycoprotein in the development of resistance by Plasmodium falciparum to chloroquine / by ...
more infohttps://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BCytochrome%20P-450%20enzyme%20system.%7D

WHO HQ Library catalog ›

    Results of search for su:{Cytochrome P-450 enzyme system.} and su-to:Cytochrome P-450 enzyme...WHO HQ Library catalog › Results of search for 'su:{Cytochrome P-450 enzyme system.} and su-to:Cytochrome P-450 enzyme...

The role of cytochrome P-450 and p-glycoprotein in the development of resistance by Plasmodium falciparum to chloroquine / by ... Results of search for su:{Cytochrome P-450 enzyme system.} and su-to:Cytochrome P-450 enzyme system. ...
more infohttps://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=ccl=su%3A%7BCytochrome%20P-450%20enzyme%20system.%7D&sort_by=relevance_dsc&limit=su-to:Cytochrome+P-450+enzyme+system.

cytochrome P-450 CYP1B1
      - CYP1B1
     Summary Report | CureHuntercytochrome P-450 CYP1B1 - CYP1B1 Summary Report | CureHunter

... an enzyme that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics; ... we found that the CYP1B1 Leu432Val polymorphism was not associated with overall urinary system cancers. ". 05/01/2014 - "In ... Enzymes and Coenzymes*Enzymes: 34502*Oxidoreductases: 9264*Oxygenases: 89*Mixed Function Oxygenases: 449*Cytochrome P-450 ... Enzyme System: 3623*Aryl Hydrocarbon Hydroxylases: 16*cytochrome P-450 CYP1B1: 671 ...
more infohttp://www.curehunter.com/public/keywordSummaryC094273-cytochrome-P-450-CYP1B1-CYP1B1.do

Cytochrome P-450 epoxygenase metabolites of docosahexaenoate potently dilate coronary arterioles by activating large...Cytochrome P-450 epoxygenase metabolites of docosahexaenoate potently dilate coronary arterioles by activating large...

Ye, D., Zhang, D., Oltman, C., Dellsperger, K., Lee, H. C., & Vanrollins, M. (2002). Cytochrome P-450 epoxygenase metabolites ... Ye D, Zhang D, Oltman C, Dellsperger K, Lee HC, Vanrollins M. Cytochrome P-450 epoxygenase metabolites of docosahexaenoate ... Ye, D, Zhang, D, Oltman, C, Dellsperger, K, Lee, HC & Vanrollins, M 2002, Cytochrome P-450 epoxygenase metabolites of ... Vascular endothelium contains cytochrome P-450 epoxygenases that transform the n-6 fatty acid arachidonate into ...
more infohttps://mayoclinic.pure.elsevier.com/en/publications/cytochrome-p-450-epoxygenase-metabolites-of-docosahexaenoate-pote

TNO Repository search for: subject:Cytochrome P-450 CYP27A1TNO Repository search for: subject:'Cytochrome P-450 CYP27A1'

The functional involvement of PPARα in the suppression of both enzymes was proven with the use of PPARα-null mice. In wild-type ... Animals · Bile Acids and Salts · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Coffee · Cytochrome P-450 ... Cafestol (20 μg/mL) had no effect on lithocholic acid 6β-hydroxylase mRNA, another enzyme involved in bile acid synthesis. LDL- ... Simultaneous impairment of other enzymes in the BS biosynthetic pathways may contribute to overall effects of EE on BS ...
more infohttps://repository.tudelft.nl/search/tno/?q=subject%3A%22Cytochrome%20P-450%20CYP27A1%22

Potent Inhibition of the Cytochrome P-450 3A-Mediated Human Liver Microsomal Metabolism of a Novel HIV Protease Inhibitor by...Potent Inhibition of the Cytochrome P-450 3A-Mediated Human Liver Microsomal Metabolism of a Novel HIV Protease Inhibitor by...

1990) Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 45:241-298. ... The reaction was started by adding the NADPH-generating system, and the incubation was conducted at 37°C for 20 min. The ratio ... cytochrome P-450. AUC. area under the curve. Cmax. maximal plasma concentration. ... 1996) Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin. Drug Metab Dispos 24:948-954. ...
more infohttp://dmd.aspetjournals.org/content/27/8/902.long

Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a<...Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a<...

Koop, D. (1986). Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Molecular Pharmacology ... At optimal concentrations of cytochrome b5, isozyme 3a was 8- to 9-fold more active than isozymes 2 and 6 and 20-fold more ... Koop, D 1986, Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a, Molecular Pharmacology ... At optimal concentrations of cytochrome b5, isozyme 3a was 8- to 9-fold more active than isozymes 2 and 6 and 20-fold more ...
more infohttps://ohsu.pure.elsevier.com/en/publications/hydroxylation-of-p-nitrophenol-by-rabbit-ethanol-inducible-cytoch-2

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.  - PubMed - NCBIP450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. - PubMed - NCBI

The human nomenclature system should be used for all species other than mouse and Drosophila. The cDNAs, mRNAs and enzymes in ... "cytochrome P450, be followed by an Arabic number denoting the family, a letter designating the subfamily (when two or more ... This revision supersedes the four previous updates in which a nomenclature system, based on divergent evolution of the ... This nomenclature system is similar to that proposed in our previous updates. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/8845856?dopt=Abstract

Evidence for distinct binding sites in the cumene hydroperoxide-dependent metabolism of benzo[a]pyrene catalyzed by cytochrome...Evidence for distinct binding sites in the cumene hydroperoxide-dependent metabolism of benzo[a]pyrene catalyzed by cytochrome...

A few constitutive cytochrome P-450 isozymes in male rat liver microsomes catalyzed the metabolism of benzo[a]pyrene (BP) in ... N2 - A few constitutive cytochrome P-450 isozymes in male rat liver microsomes catalyzed the metabolism of benzo[a]pyrene (BP) ... AB - A few constitutive cytochrome P-450 isozymes in male rat liver microsomes catalyzed the metabolism of benzo[a]pyrene (BP) ... abstract = "A few constitutive cytochrome P-450 isozymes in male rat liver microsomes catalyzed the metabolism of benzo[a] ...
more infohttps://nebraska.pure.elsevier.com/en/publications/evidence-for-distinct-binding-sites-in-the-cumene-hydroperoxide-d

CYP2C19 | Cancer Genetics WebCYP2C19 | Cancer Genetics Web

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which ... Overall, significantly elevated digestive system cancer risk was associated CYP2C19 PM with OR of 1.66 (95%CI: 1.31-2.10, P. ... BACKGROUND: The enzymes of the cytochrome P450 family (CYPs) play an important role in the metabolism of a great variety of ... RESULTS: For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% in alcoholic ...
more infohttp://www.cancerindex.org/geneweb/CYP2C19.htm

CYP3A5 | Cancer Genetics WebCYP3A5 | Cancer Genetics Web

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which ... Osteosarcoma is an aggressive cancer of the skeletal system, which is associated with a poor prognosis due to the high ... TAM is metabolized by cytochrome P450 (CYP450) enzymes, including CYP2D6, CYP3A5 and CYP2C19, whose genetic variations may have ... that recombinantly express human cytochrome P450 enzymes (CYPs). A direct comparison of CYP3A4 activity gave an eightfold ...
more infohttp://www.cancerindex.org/geneweb/CYP3A5.htm

Catechol estrogen formation in the mouse uterus and its role in implantation.Catechol estrogen formation in the mouse uterus and its role in implantation.

Cytochrome P-450 CYP1A1*. Cytochrome P-450 Enzyme System / metabolism*. Dinoprostone / pharmacology. Embryo Implantation* / ... Under the assay conditions used, E-4-H was the predominant catechol estrogen-forming monooxygenase enzyme. The inhibition of E- ... 0/Estrogens, Catechol; 16205-32-6/2-fluoroestradiol; 4G7DS2Q64Y/Progesterone; 4TI98Z838E/Estradiol; 9035-51-2/Cytochrome P-450 ... Enzyme System; EC 1.14.-/Steroid Hydroxylases; EC 1.14.14.1/Aryl Hydrocarbon Hydroxylases; EC 1.14.14.1/Cytochrome P-450 CYP1A1 ...
more infohttp://www.biomedsearch.com/nih/Catechol-estrogen-formation-in-mouse/2157614.html

Induction of cytochrome(s) P450-dependent drug metabolism in cultured MH1C1 hepatoma cells.Induction of cytochrome(s) P450-dependent drug metabolism in cultured MH1C1 hepatoma cells.

These cells were found to contain different forms of cytochrome P450, as shown by the response to inducers, namely ... Cytochromes / metabolism. Enzyme Induction / drug effects. Liver Neoplasms, Experimental / enzymology*. Methylcholanthrene / ... 10738105 - Influence of melatonin on proliferation and antioxidant system in ehrlich ascites carci.... 21342735 - Design, ... 0/Cytochromes; 56-49-5/Methylcholanthrene; 9035-51-2/Cytochrome P-450 Enzyme System; EC 1.-/Mixed Function Oxygenases; EC 1.14. ...
more infohttp://www.biomedsearch.com/nih/Induction-cytochromes-P450-dependent-drug/6518625.html

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. - NextBio...SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. - NextBio...

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Saskia ... SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic ... Much of the information on the Cytochrome P450 enzymes (CYPs) is spread across literature and the internet. Aggregating ... Cytochrome P-450 Enzyme System Databases, Genetic Databases, Nucleic Acid Databases, Protein Drug Interactions Humans ...
more infohttp://www.nextbio.com/b/search/article.nb?id=19934256

Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. |...Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. |...

We have previously reported that adenoviral-mediated delivery of cytochrome P-450 (CYP) 4A2, which catalyzes the synthesis of ...
more infohttp://www.curehunter.com/public/pubmed19675180.do

MEDLINE - Resultado p gina 1
	MEDLINE - Resultado p gina 1

... moellendorffii have cytochrome P450s in the CYP85 clans which harbors BR biosynthesis enzymes, although the P450 profiles are ... Dynamic reorganization of the endomembrane system during spermatogenesis in Marchantia polymorpha.. [So] Source:. J Plant Res; ... The genome of the liverwort Marchantia polymorpha is an important step toward development of a new plant model system (Bowman ... Furthermore, these basal land plants were found to have multiple P450s in the CYP72 clan which harbors enzymes to catabolize ...
more infohttp://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=B01.650.940.800.575.462.750

MEDLINE - Resultado p gina 1
	MEDLINE - Resultado p gina 1

The activity of the ascorbic acid-dependent demethylating Ten-eleven-translocation (Tet) enzymes was reduced in ascorbic acid ... Correct myelination is crucial for the function of the peripheral nervous system. Both positive and negative regulators within ... 0 (RNA, Messenger); 0 (Tumor Necrosis Factor-alpha); 9035-51-2 (Cytochrome P-450 Enzyme System); EC 1.14.99.1 (Cyclooxygenase 2 ... before and after peripheral nerve system (PNS) injury by Methylated DNA Immunoprecipitation Sequencing (MeDIP-Seq) and seek ...
more infohttp://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=C10.668.829.712

Case Study 8: Carbon Tetrachloride Toxicity | Environmental Medicine: Integrating a Missing Element into Medical Education |...Case Study 8: Carbon Tetrachloride Toxicity | Environmental Medicine: Integrating a Missing Element into Medical Education |...

The human fetus typically develops the enzyme system necessary for the (toxic) metabolism of CCl4 in the later months of ... CCl4toxicity is potentiated by chemicals that activate the cytochrome P-450 system. ... results of studies indicate that the human fetal MFO enzyme system may be operational in the later stages of development and ... The immediate effect of acute CCl4 exposure by all routes is central nervous system (CNS) depression. If the patient survives ...
more infohttps://www.nap.edu/read/4795/chapter/20

Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4 | Journal of...Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4 | Journal of...

1990) Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 45:241-298. ... the mechanisms by which flavonoids might exert their anticancer and other effects is through interaction with the P450 system, ... cytochrome P450. DHBG. 5-[(6,7-dihydroxy-6-keto-2-octenyl)oxy]psoralen. HBBS. Hanks balanced salt solution. HMF. 3,3′,4′,5,6,7 ... Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4. Hitomi Takanaga, Ayako ...
more infohttp://jpet.aspetjournals.org/content/293/1/230?ijkey=29de128ca52cfbe2ffd4fd3129d36a3f3267bef1&keytype2=tf_ipsecsha

Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4 | Journal of...Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4 | Journal of...

1990) Enzyme induction in the cytochrome P-450 system. Pharmacol Ther 45:241-298. ... the mechanisms by which flavonoids might exert their anticancer and other effects is through interaction with the P450 system, ... cytochrome P450. DHBG. 5-[(6,7-dihydroxy-6-keto-2-octenyl)oxy]psoralen. HBBS. Hanks balanced salt solution. HMF. 3,3′,4′,5,6,7 ... Polymethoxylated Flavones in Orange Juice Are Inhibitors of P-glycoprotein but Not Cytochrome P450 3A4. Hitomi Takanaga, Ayako ...
more infohttp://jpet.aspetjournals.org/content/293/1/230?ijkey=b4712a9c42c93f3e87a8232da35f9bcb706ecbe7&keytype2=tf_ipsecsha

TNO Repository search for: subject:Cholesterol 7alpha monooxygenaseTNO Repository search for: subject:'Cholesterol 7alpha monooxygenase'

... enzyme activity · enzyme regulation · feedback system · gene expression regulation · gene repression · genetic transcription · ... Cytochrome P-450 Enzyme System · Gene Expression Regulation, Enzymologic · In Situ Hybridization · Liver · Male · Rats · Rats, ... enzyme isolation · enzyme localization · gene expression · in situ hybridization · liver metabolism · sterol analysis · Animal ... The rate-limiting enzyme in the conversion of cholesterol into bile acids is cholesterol 7alpha-hydroxylase (CYP7A1). An A to C ...
more infohttps://repository.tudelft.nl/search/tno/?q=subject%3A%22Cholesterol%207alpha%20monooxygenase%22

Changes in the mRNA expression of CYPs and mdr1a in the | Open-iChanges in the mRNA expression of CYPs and mdr1a in the | Open-i

Bottom Line: Gene expression of the CYP family of enzymes and mdr1a was measured with quantitative real-time polymerase chain ... Intestinal and hepatic expression of cytochrome P450s and mdr1a in rats with indomethacin-induced small intestinal ulcers. ... Bottom Line: Gene expression of the CYP family of enzymes and mdr1a was measured with quantitative real-time polymerase chain ... Methods: Gene expression of the CYP family of enzymes and mdr1a was measured with quantitative real-time polymerase chain ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4196121_ijmsv11p1208g004&req=4