Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation | Biochemical...Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation | Biochemical...

... activation-induced cytidine deaminase) [3-5]. AID is a ssDNA (single-stranded DNA)-specific cytidine deaminase, expressed ... activation-induced cytidine deaminase), a DNA cytidine deaminase predominantly expressed in activated B-cells. AID is post- ... 1999) Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in ... Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation. Uttiya Basu, ...
more infohttp://www.biochemsoctrans.org/content/37/3/561

The human cytidine deaminase Apobec3F (h-A3F) a protein linked to the - Aurora Kinases as Druggable Targets in Cancer TherapyThe human cytidine deaminase Apobec3F (h-A3F) a protein linked to the - Aurora Kinases as Druggable Targets in Cancer Therapy

The human cytidine deaminase Apobec3F (h-A3F) a protein linked to the. February 28, 2017. Gap Channels ... The human cytidine deaminase Apobec3F (h-A3F) a protein linked to the previously recognized antiviral factor Apobec3G (h-A3G) ... H-A3F is carefully linked to h-A3G inside the category of cytidine deaminases situated on chromosome 22 (16). h-A3G and h-A3F ... The individual cytidine deaminase Apobec3G (h-A3G) may be a wide antiviral element in human beings against individual ...
more infohttp://www.exposed-skin-care.net/2017/02/28/the-human-cytidine-deaminase-apobec3f-h-a3f-a-protein-linked-to-the/

Affinity maturation and class switching of antibodies requires activation-induced cytidine deaminase | Adenosine Kinase...Affinity maturation and class switching of antibodies requires activation-induced cytidine deaminase | Adenosine Kinase...

Affinity maturation and class switching of antibodies requires activation-induced cytidine deaminase. Posted on July 16, 2017. ... SHM and class switching totally depend on a mutator protein, activation-induced cytidine deaminase (AID or AICD), whose ... The enzyme that initiates antibody gene mutation is definitely activation-induced cytidine deaminase (AID), the 1st protein ... Affinity maturation and class switching of antibodies requires activation-induced cytidine deaminase (AID)-dependent ...
more infohttp://cutelevision.org/affinity-maturation-and-class-switching-of-antibodies-requires-activation-induced-cytidine-deaminase/

Scientists find that proteins involved in immunity potentially cause cancerScientists find that proteins involved in immunity potentially cause cancer

... cytidine deaminases. The investigators found that APOBEC mutations can outnumber all other mutations in some cancers, ... He said scientists knew the main functions of APOBEC cytosine deaminases were to inactivate viruses that attack the body and ...
more infohttp://oncologynews.com.au/scientists-find-that-proteins-involved-in-immunity-potentially-cause-cancer/

Activation-induced cytidine deaminase definition | Drugs.comActivation-induced cytidine deaminase definition | Drugs.com

Definition of activation-induced cytidine deaminase. Provided by Stedmans medical dictionary and Drugs.com. Includes medical ... activation-induced cytidine deaminase. Definition: an enzyme implicated in the processes of somatic hypermutation and isotope ...
more infohttps://www.drugs.com/dict/activation-induced-cytidine-deaminase.html

JCI -
Involvement of activation-induced cytidine deaminase in skin cancer developmentJCI - Involvement of activation-induced cytidine deaminase in skin cancer development

Here, we have proposed that activation-induced cytidine deaminase (AID, encoded by AICDA. ) links chronic inflammation and skin ...
more infohttps://www.jci.org/articles/view/81522/figure/2

JCI -
Involvement of activation-induced cytidine deaminase in skin cancer developmentJCI - Involvement of activation-induced cytidine deaminase in skin cancer development

Here, we have proposed that activation-induced cytidine deaminase (AID, encoded by AICDA. ) links chronic inflammation and skin ...
more infohttps://www.jci.org/articles/view/81522/figure/1

Cytidine deaminase, molecular model - Stock Image A605/0226 - Science Photo LibraryCytidine deaminase, molecular model - Stock Image A605/0226 - Science Photo Library

Computer model of the enzyme, activation-induced (cytidine) deaminase (AID). The tertiary structures of two protein complexes ( ... AID catalyses the breakdown (deamination) of the amino acid cytidine in RNA (yribonucleic acid), changing it to uridine. AID is ... cytidine, cytidine aminohydrolase, cytidine deaminase, cytosine, deaminase, deaminate, deamination, edit, editing, enzyme, ... Caption: Cytidine deaminase. Computer model of the enzyme, activation-induced (cytidine) deaminase (AID). The tertiary ...
more infohttp://www.sciencephoto.com/media/6294/view/cytidine-deaminase-molecular-model

A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea | ScienceA Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea | Science

A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea ... A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea ... A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea ... A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea ...
more infohttp://science.sciencemag.org/content/324/5927/657.full

The cell cycle restricts activation-induced cytidine deaminase activity to early G1 | JEMThe cell cycle restricts activation-induced cytidine deaminase activity to early G1 | JEM

activation-induced cytidine deaminase. Cμ. constant μ region. CSR. class switch recombination. ER. estrogen receptor ligand- ... The cell cycle restricts activation-induced cytidine deaminase activity to early G1. View ORCID ProfileQiao Wang, Kyong-Rim ... Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase. Annu. Rev. Pathol. 8:79-103. doi:10.1146/ ... Epigenetic targeting of activation-induced cytidine deaminase. Proc. Natl. Acad. Sci. USA. 111:18667-18672. doi:10.1073/pnas. ...
more infohttp://jem.rupress.org/content/early/2016/12/19/jem.20161649

Cytidine deaminase - WikipediaCytidine deaminase - Wikipedia

Taysi S, Polat MF, Sari RA, Bakan E (2003). "Serum adenosine deaminase and cytidine deaminase activities in patients with ... Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene. This gene encodes an enzyme involved in pyrimidine ... 2003). "[Expression of cytidine deaminase mRNA in bone marrow cells from patients with acute leukemia]". Zhongguo Shi Yan Xue ... "Entrez Gene: CDA cytidine deaminase". Wentworth DF, Wolfenden R (1976). "On the interaction of 3,4,5,6-tetrahydrouridine with ...
more infohttps://en.wikipedia.org/wiki/Cytidine_deaminase

Addgene: MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.Addgene: MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase.

MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. Teng G, Hakimpour P, Landgraf P, Rice A, Tuschl ...
more infohttp://www.addgene.org/browse/article/2368/

A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.  - PubMed - NCBIA role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. - PubMed - NCBI

A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.. Gourzi P1, Leonova T ... Activation-induced cytidine deaminase (AID) is specifically expressed in the germinal centers of lymphoid organs, where it ... AICDA (activation-induced cytidine deaminase). *Cytidine Deaminase. Grant support. *R01 AI071029/AI/NIAID NIH HHS/United States ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/16782033?dopt=Abstract

Addgene: The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.Addgene: The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.

The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination. Besmer E, Market E ...
more infohttp://www.addgene.org/browse/article/1664/

Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics |...Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics |...

Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics. ... Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics ... Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics ... Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics ...
more infohttp://clincancerres.aacrjournals.org/content/12/6/1794.figures-only

Activation-induced cytidine deaminase - WikipediaActivation-induced cytidine deaminase - Wikipedia

This gene encodes a DNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic ... Activation-induced cytidine deaminase, also known as AICDA and AID, is a 24 kDa enzyme which in humans is encoded by the AICDA ... Martin A, Bardwell PD, Woo CJ, Fan M, Shulman MJ, Scharff MD (2002). "Activation-induced cytidine deaminase turns on somatic ... Bransteitter R, Sneeden JL, Allen S, Pham P, Goodman MF (2006). "First AID (activation-induced cytidine deaminase) is needed to ...
more infohttps://en.wikipedia.org/wiki/Activation-induced_cytidine_deaminase

The Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites - InfoscienceThe Interplay between Cytidine Deaminases, HIV and Domesticated Genetic Parasites - Infoscience

APOBEC3A, a single-domain cytidine deaminase, can block efficiently the parvovirus adeno-associated virus type 2 (AAV-2) or the ... APOBEC3G is formed of two independent cytidine deaminase domains, only the C-terminal of which is catalytically active. ... APOBEC3 family of cytidine deaminases (section 2). Since certain retrotransposons are related to exogenous retroviruses, it is ... APOBEC ; cytidine deaminase ; KRAB ; KAP1 ; HIV ; AAV ; LINE ; retrovirus ; retrotransposon ; restriction ; innate immunity ; ...
more infohttps://infoscience.epfl.ch/record/149073

CDA / Cytidine Deaminase Antibody (AP) for WB/Western LS-C503318CDA / Cytidine Deaminase Antibody (AP) for WB/Western LS-C503318

Cytidine Deaminase antibody LS-C503318 is an AP-conjugated rabbit polyclonal antibody to human Cytidine Deaminase (CDA). ... Cytidine Deaminase antibody LS-C503318 is an AP-conjugated rabbit polyclonal antibody to human Cytidine Deaminase (CDA). ... Cytidine Deaminase antibody LS-C503318 is an AP-conjugated rabbit polyclonal antibody to human Cytidine Deaminase (CDA). ... Popular CDA / Cytidine Deaminase Products. CDA / Cytidine Deaminase Antibody (N‑Terminus) IHC‑plus™ LS‑B1823 ...
more infohttps://www.lsbio.com/antibodies/cda-antibody-cytidine-deaminase-antibody-ap-wb-western-ls-c503318/516879

CDA / Cytidine Deaminase Antibody for WB/Western, ELISA LS-C189974CDA / Cytidine Deaminase Antibody for WB/Western, ELISA LS-C189974

Cytidine Deaminase antibody LS-C189974 is an unconjugated rabbit polyclonal antibody to human Cytidine Deaminase (CDA). ... CDA Antibody, Cytidine aminohydrolase Antibody, Cytidine deaminase Antibody, Small cytidine deaminase Antibody, CDD Antibody, ... About CDA / Cytidine Deaminase. CDA / Cytidine Deaminase is an enzyme involved in pyrimidine salvaging. The encoded protein ... Cytidine Deaminase antibody LS-C189974 is an unconjugated rabbit polyclonal antibody to human Cytidine Deaminase (CDA). ...
more infohttps://www.lsbio.com/antibodies/cda-antibody-cytidine-deaminase-antibody-elisa-wb-western-ls-c189974/197877

Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination | G3: Genes | Genomes | GeneticsActivation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination | G3: Genes | Genomes | Genetics

Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination Message Subject (Your Name) has forwarded a ... Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination. Catarina S. Cortesao, Raquel F. Freitas and ... Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination. Catarina S. Cortesao, Raquel F. Freitas and ... Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination. Catarina S. Cortesao, Raquel F. Freitas and ...
more infohttp://www.g3journal.org/content/3/4/645

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under...Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under...

For example, cytidine deaminase (CDA) deficiency leads to an excess of dCTP, slowing the replication fork. We describe here a ... Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under ... Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under ... Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/26181065?dopt=Abstract

A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin...A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin...

Activation-induced cytidine deaminase (AID) is a DNA mutator enzyme essential for adaptive immunity. AID initiates somatic ... A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin ...
more infohttps://www.sigmaaldrich.com/catalog/papers/23183374

Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute...Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute...

Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute ... "Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute ...
more infohttps://www.hindawi.com/journals/bmri/2015/309491/cta/

A Polymorphism in the Cytidine Deaminase Promoter Predicts Severe Capecitabine-Induced Hand-Foot Syndrome | Clinical Cancer...A Polymorphism in the Cytidine Deaminase Promoter Predicts Severe Capecitabine-Induced Hand-Foot Syndrome | Clinical Cancer...

Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics Clin ... A Polymorphism in the Cytidine Deaminase Promoter Predicts Severe Capecitabine-Induced Hand-Foot Syndrome. Daniela Caronia, ... Experimental Design: We genotyped a total of 13 polymorphisms in the carboxylesterase 2 (CES2) gene, the cytidine deaminase ( ... Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism J Clin Oncol 2007 ...
more infohttp://clincancerres.aacrjournals.org/content/17/7/2006

Immunoglobulin Heavy Chain Locus Events and Expression of Activation-Induced Cytidine Deaminase in Epithelial Breast Cancer...Immunoglobulin Heavy Chain Locus Events and Expression of Activation-Induced Cytidine Deaminase in Epithelial Breast Cancer...

Activation-induced cytidine deaminase expression and germ-line switch transcript analysis. A nested RT-PCR approach to detect ... Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications ... Strikingly, six of six cell lines expressed activation-induced cytidine deaminase (AID) essential for mutational and switch ... Immunoglobulin Heavy Chain Locus Events and Expression of Activation-Induced Cytidine Deaminase in Epithelial Breast Cancer ...
more infohttp://cancerres.aacrjournals.org/content/66/8/3996