A Novel Theranostic Combination of Near-infrared Fluorescence Imaging and Laser Irradiation Targeting c-KIT for...
GIST-T1 cells pre-incubated with IR700-12A8 were incubated with vehicle, N-acetyl-l-cysteine (NAC), or sodium azide (NaN3) for ... and the media was replaced with phenol red-free RPMI1640 medium containing 10 mM N-acetyl-L-cysteine (NAC), 10 mM, 30 mM sodium ... N-acetyl-L-cysteine; TUNEL: terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling; SD: ...
Development of functional nanomedicines for tumor associated macrophages-focused cancer immunotherapy
Activation of MAPK and NF-κB pathways via the oxidation of cysteine residues of proteins by photo-triggered ROS. Breast cancer ... fabricated mixed polypeptide NPs based on n-butylamine-poly(L-lysine)-b-poly(L-cysteine) (PLL-PLC) polypeptides coated with ... and NF-κB via the oxidation of cysteine residues of proteins [93] (Figure 11A, B). However, some studies proposed the opposite ... L-cysteine); miR155: MicroRNA-155; C: carbon; Si: silicon; P: phosphorus; GO: graphene oxide; HMONs: hollow mesoporous ...
CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders
However, under conditions of low or no DCT and Tyrp-1 expression, it reacts with cysteine and becomes pheomelanin. Thus, the ...
An Activatable Near-Infrared Chromophore for Multispectral Optoacoustic Imaging of Tumor Hypoxia and for Tumor Inhibition
Qi Y, Huang Y, Li B, Zeng F, Wu S. Real-Time Monitoring of Endogenous Cysteine Levels In Vivo by near-Infrared Turn-on ... dye conjugate as an NIR fluorescent probe for the selective detection of mitochondrial glutathione over cysteine and ...
Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications
Connective tissue growth factor expression (CTGF, an inhibitor of angiogenesis), cysteine-rich protein 61 (Cyr61), ...